Clinical trials: Bupivacaine
Posterior Lumbosacral Spine Fixation Surgeries
Dexmedetomidine Combined With Bupivacaine for Erector Spinae Plane Block
As the posterior lumbosacral spine fixation surgeries are common spine procedures done nowadays due to different causes and as this spine procedure is mostly accompanied with moderate to severe postoperative pain, so it is…
- Trial name
- NCT05590234
- Testing
- Dexmedetomidine injection, Bupivacaine 0.25% Injectable Solution, normal saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- October 6 University
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Undergoing Hysterectomy
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing hysterectomy on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993226
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 14 sites in France, Germany and 4 more
- Volunteers
- 115 people
- Sponsor
- Durect
Open Reduction Internal Fixation(ORIF) of Lateral Malleolus
Sciatic Nerve Block for Ankle/Foot Surgeries. A Comparison Between a Premixed Solution of Lidocaine Plus Bupivacaine and Consecutive Infiltration of Lidocaine and Bupivacaine
Regional anaesthesia has become the cornerstone of multimodal analgesia. With the advent of ultrasound guided nerve blocks regional anaesthesia has achieved both greater efficacy and a better safety profile as the injection of…
- Trial name
- NCT01756443
- Testing
- 2% lidocaine/adrenaline and 0.5% bupivacaine
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Cork University Hospital
Breast Cancer
Bupivacaine Versus Liposomal Bupivacaine For Breast Pain Management After Breast Recontruction
The purpose of this study is to determine the most effective way to control post-operative breast pain for patients undergoing a unilateral, immediate breast reconstruction.
- Trial name
- NCT03393117
- Testing
- Liposomal Bupivacaine, Bupivacaine, Patient-Controlled Analgesia Pump
- Sponsor
- Case Comprehensive Cancer Center
Colorectal Surgery
Comparing Liposomal Bupivacaine Versus Standard Bupivacaine in Colorectal Surgery
The purpose of this study is to compare the difference between two different pain control methods in patients who will be having a colorectal surgery
- Trial name
- NCT03702621
- Testing
- liposomal Bupivacaine, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Indiana University
Pelvic Organ Prolapse, Postoperative Pain
Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain?
In current practice, packing in the vagina overnight after vaginal surgery is typically used to prevent post-surgical vaginal bleeding.
- Trial name
- NCT03266926
- Testing
- Bupivacaine, Premarin Vaginal cream
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Acute Cholecystitis, Postoperative Pain
Irrigation of Bupivacaine at the Surgical Bed for Postoperative Pain Relief After Laparoscopic Cholecystectomy for Acute Cholecystitis
This study aims to compare the effectiveness of irrigation of 0.5% bupivacaine versus normal saline at the gallbladder surgical bed in reducing postoperative pain following laparoscopic cholecystectomy for acute cholecystitis.
- Trial name
- NCT07851935
- Testing
- Bupivacaine 0.5%, Normal Saline 0.9%
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Ziauddin University
Anesthesia, Local
Bupivacaine Supplementation For Postoperative Pain Control In Surgical Removal Of Mandibular Third Molars
Control of postoperative pain is a foremost goal in achieving a satisfactory postoperative recovery. Surgical removal of lower third molars is accompanied by postoperative pain that is at its peak in the first 12 hours.
- Trial name
- NCT02353676
- Testing
- Bupivacaine, SALINE
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cosmozone Dental Clinic
Caudal Block for Postoperative Analgesia
Effect of Adding Different Concentrations of Dexmedetomidine to Bupivacaine in Caudal Block for Pediatrics
Pain is one of the medical problems frequently misdiagnosed, undertreated, and poorly under-stood, particularly in children.Poor pain management during childhood may have long-term deleterious impacts, including damaging…
- Trial name
- NCT06668220
- Testing
- Dexmedetomidine, Bupivacain
- Volunteers
- 50 people
- Sponsor
- Assiut University
Laparoscopic Orcheopexy
Transversus Abdominis Plane Block Using Dexmedetomidine and Bupivacaine
Pediatric laparoscopy has been first described in 1923 by Kelling but its use has increased since last decade. A laparoscopic approach offers several advantages over an open procedures; potentially reduces the surgical stress and…
- Trial name
- NCT03156296
- Testing
- Dexmedetomidine, Bupivacaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Paravertebral Block
Effect of Addition of Fentanyl or Dexamethasone or Both to Bupivacaine in Paravertebral Block for Patients Undergoing Major Breast Surgery
This study evaluated the analgesic efficacy of fentanyl and dexamethasone in combination with bupivacaine for single-shot paravertebral block (PVB) in patients undergoing major breast surgery.
- Trial name
- NCT03480308
- Testing
- Fentanyl, Dexamethasone, Bupivacaine
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Assiut University
Laparoscopic Cholecystectomy
Intraperitoneal Analgesia After Laparoscopic Cholecystectomy
Although laparoscopic cholecystectomy is associated with less pain than contemporary open procedures; it is definitely not pain free and the magnitude of postoperative shoulder and abdominal pain in the early postoperative period…
- Trial name
- NCT00950625
- Testing
- lignocaine, bupevacaine
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Aga Khan University
Knee Osteoarthritis
Liposomal Bupivacaine vs Adductor Canal Block in Total Knee Arthroplasty
This study is being done to evaluate the outcomes of patients undergoing total knee replacement with two different methods of local pain control:shots of liposomal bupivacaine, a long acting anesthetic, directly into the knee…
- Trial name
- NCT02863120
- Testing
- liposomal bupivacaine, bupivacaine HCl, Ropivacaine
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Texas Orthopaedics, Sports and Rehabilitation Associates
Liposomal Bupivacaine, Preperitoneal Infiltration
Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy
Upper abdominal open surgery is associated with significant trauma, and postoperative pain management poses considerable challenges.
- Conditions
- Liposomal Bupivacaine, Preperitoneal Infiltration, Analgesia
- Trial name
- NCT07271979
- Testing
- Liposomal bupivacaine, ropivacaine
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Qilu Hospital of Shandong University
Abdominal Cancer
Effect of Wound Infiltration by Ketamine Versus Dexmedetomidine Added to Bupivacaine on Surgical Stress
This study aims to compare the effects of local wound infiltration with ketamine versus dexmedetomidine when added to bupivacaine on stress response and postoperative pain in lower abdominal cancer surgery.
- Trial name
- NCT02927379
- Testing
- Dexmedetomidine, Ketamine, Bupivacaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Pain
Peritubal Infiltration of Bupivacaine in PCNL
Patients may feel significant pain at the surgery site after they wake up from the surgery. Usually pain is managed in the ward by giving strong pain medication that may slow down your mobilization and recovery process.
- Trial name
- NCT02198027
- Testing
- Bupivacaine, Normal saline infiltration
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Indus Hospital and Health Network
Rib Fractures
Continuous Intercostal Nerve Blockade for Traumatic Rib Fractures
Rib fractures are common injuries in accident patients and can be associated with significant pain during recovery. If poorly controlled, pain from splinting due to rib fractures can result in difficulty in breathing leading to…
- Trial name
- NCT02604589
- Testing
- hydromorphone hydrochloride, Infusion catheter placement, bupivicaine 0.25%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Anthony Iacco
More Effective Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination, More Prolonged Duration of Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination
Comparing Effect of Adding Ketamine Versus Dexmedetomidine to Bupivacaine in Pec 11 Modified Block on Postoperative Pain Control in Patients Undergoing Breast Surgery
in our study we are trying to reach to the preferred adjuvant from either ketamine or dexmedetomidine to be added to bupivacaine local anesthetic during pec 11 modified block as regard its efficacy and duration of postoperative…
- Trial name
- NCT04380168
- Testing
- Modified pec11 trunk block
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Ain Shams University
Postoperative Pain, Breast Reconstruction
Effectiveness of Exparel TAP Block in Breast Free Flap Reconstruction
Transversus Abdominis Plane (TAP) block is a useful tool in pain management after abdominal surgery. It is a regional nerve block that targets T6-L1 thoracolumbar nerves running in the plane between internal oblique and…
- Trial name
- NCT04777591
- Testing
- Liposomal bupivacaine TAP block, Bupivacain
- Where
- 2 sites in United States
- Volunteers
- 117 people
- Sponsor
- University of Virginia
Obesity
Intraperitoneal Dexmedetomidine Versus Ketamine With Bupivacaine For Postoperative Analgesia
Post-laparoscopic sleeve pain management is essential for early mobilization of the patient and so on decrease post-operative complication.
- Trial name
- NCT04525274
- Testing
- normal saline, dexmedetomidine, Ketamine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University