Clinical trials: Burn, open to volunteers
Scar Conditions and Fibrosis of Skin, Scar Quality Assessment and Safety
Scar Remodeling After Burn Injury Using Allogeneic Adipose-derived Stromal Cells
The present project serves to test whether stem cell therapy offers a new treatment option for the scars of burn survivors. In Denmark, 12.000 people seek medical assistance every year for burn injuries leaving thousands of…
- Conditions
- Scar Conditions and Fibrosis of Skin, Scar Quality Assessment and Safety, Scar Tissue
- Trial name
- ScarASC (NCT07635875)
- Testing
- Allogeneic adipose-Derived Mesenchymal Stromal Cells, Cryostor CS10 + Ringers Lactate
- Where
- Denmark
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Pain, Pediatric ALL
VR-PAT and fNIRS to Identify CNS Biomarkers of Pain
This study aims to use functional near-infrared spectroscopy (fNIRS) to identify and quantify pain biomarkers during burn dressing changes and pain relief induced by virtual reality (VR).
- Conditions
- Acute Pain, Pediatric ALL, Procedural Pain, Burns
- Trial name
- NCT06303687
- Testing
- VR-PAT
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Nationwide Children's Hospital
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Burn Scar, Burn Wound
Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients
The goal of this study is to see how an ingredient called kynurenic acid (which we named "FS2") affects scar formation in people with burn injuries that need skin graft surgery.
- Trial name
- NCT06807021
- Testing
- IP1 control cream (Vehicle base), IP2 - 0.5% w/w FS2
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Birch BioMed Inc
Burns, Burn Injury
Deepview HHF Training and Validation Study
The purpose of this Study is to help expand the use of the DeepView AI System so that it can assess burn injuries on the hands, head/face, and feet. To do this, the Study will collect new images of burns in these areas.
- Conditions
- Burns, Burn Injury, Diagnostic
- Trial name
- UK HHF (NCT07677657)
- Testing
- DeepView AI System
- Volunteers
- 280 people
- Sponsor
- SpectralMD
Burn Wounds, Burn
The Effect of Hologram Application on Pain, Anxiety, and Fear Levels in Children During Burn Dressing
The process of dressing burn injuries has been shown to cause both physical and psychological difficulties. In children, this process is particularly associated with intense pain and anxiety.
- Trial name
- NCT06992895
- Testing
- The visual presentation utilizes a three-dimensional holographic fan device.
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Impact of ROM Exercises on Pain and Functional Ability in Patients With Second -Degree Burns
Impact of Range of Motion Exercises on Pain and Functional Ability
The goal of this quasi-experimental study is to evaluate the effect of range of motion (ROM) exercises on pain and functional ability among adult patients of both genders with second-degree burn injuries affecting the upper…
- Trial name
- ROM-SDB (NCT07883863)
- Testing
- Range of Motion exercises
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Facial Scarring, Facial Trauma
Tools for Return of Facial Function
This study will evaluate novel intraoral (inside-the-mouth) splints designed to gently stretch facial tissues that have become tight or scarred following facial trauma, including burn injuries and gunshot wounds.
- Conditions
- Facial Scarring, Facial Trauma, Burn, Orofacial Contracture
- Trial name
- NCT07825844
- Testing
- Intraoral Stretching Splints
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns
Effect of Core Stability and Sensorimotor Training Exercises on Postural Stability Post Lower Limb Burn
The purpose of the study is to determine the effect of core stability and sensorimotor training exercises on postural stability post lower limb burn.
- Trial name
- NCT06718829
- Testing
- Core Stability Exercises, Sensorimotor Training Exercises, Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Sepsis, Burn Injury
Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1
This study is following adult patients with serious burn injuries to better understand how their bodies respond to treatment and recovery.
- Conditions
- Sepsis, Burn Injury, Wound Healing, Critical Illness
- Trial name
- NCT07249762
- Testing
- Observational Cohort (No Intervention)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Burn Wounds, Third-Degree Burn Wounds
HUMSCs Combined With Col I to Third-Degree Burn Wound
To evaluate the safety and tolerability of human umbilical cord mesenchymal stem cells combined with bovine type I collagen in the treatment of third-degree burn wounds.
- Trial name
- NCT07530003
- Testing
- HUMSCs combined with bovine type I collagen, bovine type I collagen, Sterile blank dressing / Vaseline gauze
- Where
- China
- Volunteers
- 108 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Burns, Pain, Procedural
Virtual Reality for Pain and Fear in Children With Burns
Burn injuries are very painful for children, especially during dressing changes when the wound is cleaned and re-bandaged. This procedure, while necessary, can cause pain, fear, and distress that may make children afraid of…
- Conditions
- Burns, Pain, Procedural, Pain, Acute, Fear
- Trial name
- VR-PFB (NCT07740980)
- Testing
- Virtual Reality (VR) Distraction, Standard Burn Dressing Care
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Burn Injury, Hypoxia
Comparison of High Flow Nasal Oxygen and Nasal Cannula in Burn Patients Under Sedation
Burn-related pain is severe and often difficult to manage. Burn patients often require high doses of opioids and anxiolytics. Anesthetic agents used during sedation such as benzodiazepines, propofol and opioids can cause…
- Conditions
- Burn Injury, Hypoxia, Sedation
- Trial name
- NCT06756906
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Pain
Virtual Reality for Pain Management in Burn Patients
This study is a randomized proof-of-concept study to assess the efficacy of Virtual Reality (VR) vs standard of care in 50 adult patients in the New York Presbyterian Burn Unit.
- Trial name
- NCT04685486
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Burns, Gait Dysfunction
The Effect of Mobile Robot Assisted Gait Training on Gait Performance in Chronic Patients With Impaired Gait Function After Burn Injury
This study aims to examine the clinical effectiveness of gait training using wearable robots in patients with impaired gait function after burn injury.
- Conditions
- Burns, Gait Dysfunction, Robot Training
- Trial name
- NCT07277166
- Testing
- wearable robot training
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Hangang Sacred Heart Hospital
Donor Site Complication, Burn
Blue Light for Donor Site Healing in Burn Patients
The goal of this clinical trial is to learn whether blue light (BL) photobiomodulation can improve the healing of donor site (DS) wounds in patients with burn injuries who are treated surgically.
- Conditions
- Donor Site Complication, Burn, Photobiomodulation Therapy, Blue Light
- Trial name
- CGU01_BL (NCT07453927)
- Testing
- Photobiomodulation with blue light
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- AUSL Romagna Rimini
Partial-thickness Burn Wounds
Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns
The goal of this randomized controlled clinical trial is to determine whether use of Kericis Intact Fish Skin Graft (IFSG) can decrease the amount of autograft tissue needed for treatment of deep partial-thickness burns in…
- Trial name
- LOGI (NCT07326657)
- Testing
- Intact fish skin graft, autograft
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Kerecis Ltd.
Burn, Fracture
Clinical Effectiveness of Robot-assisted Gait Training in Patients With Lower Limb Burns Accompanied by Fractures: Pilot Study
Gait dysfunction, common in patients with lower limb burns accompanied by fractures, requires acute rehabilitation. This study investigated the clinical effects of robot-assisted gait training (RAGT) on gait function in patients…
- Conditions
- Burn, Fracture, Robot Assisted Gait Training
- Trial name
- NCT07578753
- Testing
- robot assisted gait training
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Hangang Sacred Heart Hospital
Reconstruction of First Web Space
Reconstruction of First Web Space After Trauma and Burn
assess and compare the functional and aesthetic outcomes of different surgical techniques used for reconstruction of post-traumatic and post-burn first web space obliteration.
- Trial name
- NCT07762404
- Testing
- Reconstruction of post burn first web space obliteration in hand, First web space Reconstruction, Reconstruction of first web space
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Partial-thickness Burn, Pain
Banana Leaves as a Wound Dressing for Partial Thickness Second Degree Burns in Adult Patients.
This study plans to look at the benefits of banana leaves as a primary burn wound dressing. Study patients will be compared to historical patients
- Conditions
- Partial-thickness Burn, Pain, Second Degree Burn
- Trial name
- NCT07453732
- Testing
- Banana leaf dressing
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver