Clinical trials: Burn Injury
Burn Hand
Effects of Visual Feedback Therapy on Post Burn Children
Visual feedback therapy is a cheap, easy, and, most importantly, patient-directed treatment that may improve the recovery of hand motor functional skills.
- Trial name
- NCT06231173
- Testing
- Visual Feedback Therapy and Conventional Therapy, Conventional Therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Burn Injury
Module on Preventing Fire, Burns and Scalds Injury Among Children
The main aim of this intervention study is to test the hypothesis if school based educational intervention program will significantly improve the knowledge of primary school student on childhood burn prevention in Kuala Lumpur.
- Trial name
- NCT03618940
- Testing
- Knowledge and Attitude on burn prevention
- Where
- Malaysia
- Volunteers
- 2,335 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Pruritus, Burns
Study of the Efficacy, Safety & Tolerability of Serlopitant for Pruritus (Itch) After Burn Injury
Study of the Efficacy, Safety \& Tolerability of Serlopitant for Pruritus (Itch) After Burn Injury
- Trial name
- AUBURN (NCT02975271)
- Testing
- Serlopitant
- Where
- 7 sites in United States
- Volunteers
- 1 people
- Sponsor
- Vyne Therapeutics Inc.
Trauma, Burns
Inflammation and the Host Response to Injury (Burns)
The purpose of this study is to help improve our understanding of the biology involved in the body's response to serious trauma or burn injury.
- Conditions
- Trauma, Burns, Multiple Organ Failure
- Trial name
- NCT00257244
- Where
- 4 sites in United States
- Volunteers
- 280 people
- Sponsor
- Massachusetts General Hospital
Burned Children, Ceftazidime Treatment
Ceftazidime in Burn Children
Concentrations and effects of Ceftazidime in critically ill burn children are unpredictable and the risk of under-exposure may be associated with poor clinical outcomes.
- Trial name
- CEFTAZOPTIM (NCT03881800)
- Testing
- titration- blood sample
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Wounds, Venous Leg Ulcers (VLUs)
Efficacy of Carbonlife Amniotic Tissue Product in the Treatment of Chronic Wounds
Chronic wounds constitute a significant global health burden, affecting millions of individuals and contributing to increased morbidity, diminished quality of life, and rising healthcare costs.
- Conditions
- Chronic Wounds, Venous Leg Ulcers (VLUs), Diabetic Foot Ulcers (DFUs), Arterial Ulcers
- Trial name
- NCT07223892
- Testing
- Amniotic Tissue Allograft
- Volunteers
- 600 people
- Sponsor
- Bardia Anvar
Burns
Response of Muscle Mechanical Properties to Early Multi-angles Isometric Exercises in Acute Burn Patients
This study will be conducted to investigate the effect of early multi-angle isometric exercise on muscle properties in post-burn patients.
- Trial name
- ABP (NCT07832955)
- Testing
- isometric exercise program, conventional physical therapy
- Volunteers
- 40 people
- Sponsor
- Cairo University
Skin Graft
Effect of Platelet Rich Plasma and Keratinocyte Suspensions on Wound Healing
This prospective randomized trial evaluated the impact of autologous keratinocytes suspended in platelet concentrates on healing skin graft donor site wounds.
- Trial name
- NCT00856934
- Testing
- Autologous Platelet Rich Plasma, Keratinocyte suspension, Standard dressings
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Skin Burn Degree Second
Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds
The purpose of this study is to determine the extent to which Keramatrix dressing promotes the healing of second-degree burn wounds in pediatric patients.
- Trial name
- NCT01790763
- Testing
- Keramatrix, Mepilex
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Infections, Gram-Positive Bacterial, Abscess
Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)
Serious infections caused by resistant bacteria are becoming more of a medical problem throughout the world. One of the ways to deal with this problem is to develop new drugs that can control these bacteria.
- Conditions
- Infections, Gram-Positive Bacterial, Abscess, Burns, Cellulitis
- Trial name
- FAST (NCT00061633)
- Testing
- Telavancin, Vancomycin or antistaphylococcal penicillin
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Cumberland Pharmaceuticals
Skin Condition, Cleft Lip and Palate
Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study
A visible difference can have a profound impact in a society with a massive emphasis on appearance and "looks". A vulnerable group is adolescents with a condition affecting their appearance as a result of injuries (burns…
- Conditions
- Skin Condition, Cleft Lip and Palate, Burns, Other Conditions Leading to a Visible Difference
- Trial name
- UNGFaceIT (NCT03165331)
- Testing
- Ung Face IT
- Where
- Norway
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Mesenchymal Stem Cell-derived Pleiotropic Factor in Treating Residual Burn Wound
Mesenchymal Stem Cell Conditioned Medium-derived Pleiotropic Factor in Treating Residual Burn Wound
Treatment of extensive deep burn residual wounds is a common problem in burn plastic surgery. Due to bacterial invasion, excessive maturation of granulation tissue, poor abrasion resistance of new epithelium, and coexistence of…
- Trial name
- NCT04235296
- Testing
- epidermal growth factor, mesenchymal stem cell conditioned medium-derived pleiotropic factor
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Smoke Inhalation Patients
Impact of Hydroxocobalamine on Outcome of Smoke Inhalation Injury Admitted to the ICU
In Europe, hydroxocobalamin (cyanokit) has been used for suspicion of cyanide intoxication associated with the inhalation of fire smoke (1). However, the impact of hydroxocobalamin on outcome has never been thoroughly evaluated.
- Trial name
- COB-AKI (NCT03558646)
- Testing
- There is no intervention planned (observational)
- Where
- France
- Volunteers
- 739 people
- Sponsor
- Saint-Louis Hospital, Paris, France
Burn Injury, Acute Wound
Cutaneous Microcirculation After Remote Ischemic Preconditioning
In plastic and reconstructive surgery, treatment strategies of second-degree burns, superficial wounds and chronic wounds aim at reducing infection and improving microcirculation.
- Conditions
- Burn Injury, Acute Wound, Chronic Wound
- Trial name
- NCT02417805
- Testing
- Intervention: Remote Ischemic Preconditioning
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Schleswig-Holstein
Burn Scar, Scar
Mechanistic Basis of Ablative Carbon Dioxide Laser in Treating Hypertrophic Scars
This is an observational cohort study which will look at the biomarkers from blood and tissue sample for adult patients with hypertrophic scarring due to burns/trauma incident over 12 months from date of recruitment.
- Trial name
- SMOOTH (NCT04736251)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Naiem Moiemen
Cryotherapy Effect, Burn Scar
Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars.
To investigate the effect of 10,600 nm CO2 laser combined with Zimmer Cryo 6 forced cold air device on the comfort and efficacy of patients with burn scars or post-operative linear scars, and to provide a safer, more effective…
- Conditions
- Cryotherapy Effect, Burn Scar, Scar; Previous Cesarean Section
- Trial name
- NCT05555602
- Testing
- Cold-air cooling
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaiyang Lv, MD-PhD
Burn
Low Dose Ketamine VR Analgesia During Burn Care Procedure
The purpose of the research is to see whether a low dose of ketamine, a medication used to reduce pain, enhances the effectiveness of a virtual reality video game, which is used as a form of distraction from pain during a painful…
- Trial name
- VRK (NCT01889537)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Burn
Burn Micronutrient Repletion Pilot Study
Burn injury patients undergo a series of metabolic changes that, if untreated, could lead to reduced health outcomes. Nutrition is thought to play a vital role in post-burn recovery.
- Trial name
- NCT00879723
- Testing
- Vitamin and Mineral supplementation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Southern Illinois University
Burns
Platelet-Rich Plasma (PRP) in Reconstructive Surgery on Children With Retractable Burn Sequelae on Extremities
Does the addition of Platelet-Rich Plasma (PRP) to release of burn contractures and skin graft on the limbs of children with retractable burn sequelae reduce the initial time of the compressive treatment and maintain or lower the…
- Trial name
- NCT00858442
- Testing
- With PRP
- Where
- Chile
- Volunteers
- 44 people
- Sponsor
- Corporation for the Aid of Burned Children
Burn, Child
Virtual Reality Distraction for Procedural Pain Management and Anxiety in Children With Burn Injuries : A Pilot Study
Procedural pain is the most intense and often undertreated pain associated with burn injuries. The use of analgesics does not always provide optimal relief and is accompanied by several side effects.
- Conditions
- Burn, Child, Pain, Anxiety
- Trial name
- NCT02794103
- Testing
- Virtual Reality Distraction
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- St. Justine's Hospital