Clinical trials: Burn Patients
Burns
Comparison of Fluid Resuscitation in Pediatric Burn Patients Using Crystalloids and With Albumin on Day Two.
The goal of this comparative, interventional randomized controlled trial is to use albumin during resuscitation in pediatric burn patients on day 2, as it can reduce extravasation of fluids and decrease the overall fluid…
- Trial name
- NCT06224777
- Testing
- 5% Albumin (human) Solution, Paeds solution
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- King Edward Medical University
Burns
Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Children
This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in children with partial deep dermal and full thickness burns.
- Trial name
- NCT03229564
- Testing
- EHSG-KF, STSG
- Where
- 4 sites in Italy, Netherlands and 1 more
- Volunteers
- 12 people
- Sponsor
- CUTISS AG
Pain, Anxiety
Effect of Playing an Audio Clip for Pain and Anxiety Control in Patients While Dressing Burn Wounds
The aim of this clinical trial is to assess the effect of playing patient preferred audio clip for controlling the pain and anxiety in patients while dressing burn wounds.
- Trial name
- NCT05515302
- Testing
- Audio Clip
- Where
- Qatar
- Volunteers
- 100 people
- Sponsor
- Hamad Medical Corporation
Burn Surgery, Dobutamine
Supernormal Oxygen Delivery for Patients With Severe Burns
This is a randomized double-blinded study to investigate in which the groups are designated as the control group and the goal-directed fluid therapy group to further evaluate significant differences in rate of complications…
- Trial name
- NCT05241912
- Testing
- Dobutamine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou Red Cross Hospital
Burn Injury
Vitamin E Supplementation in Burn Patients
Burned patients because of their increased oxidative stress have severely depleted vitamin E, which is a dietary antioxidant. Oxidative stress is responsible for much of the pathophysiology seen in burned patients, which leads to…
- Trial name
- NCT01413620
- Testing
- dl-alpha-tocopheryl acetate
- Where
- United States
- Sponsor
- Shriners Hospitals for Children
Aromatherapy
Effect of Aromatherapy on Pain, Anxiety and Sleep Quality in Burn Patients
This study, which was designed as a randomized placebo-controlled experimental study, was conducted to determine the effect of inhalation aromatherapy with lavender essential oil on pain, anxiety and sleep quality in burn…
- Trial name
- NCT05728190
- Testing
- steril/salin water, Lavender essential oil
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sema Koçaşlı
Full Thickness Skin Defects
The Safety of a Novel Acellular Dermal Template as Treatment for Burns and Scars
In this study the safety and feasibility of an acellular dermal template (Novomaix), combined with split thickness skin grafts, for use in patients with full thickness skin defects, is tested.
- Trial name
- NCT02164760
- Testing
- Novomaix dermal substitute in combination with STSG
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 13 people
- Sponsor
- Association of Dutch Burn Centres
Burn Shock
Evaluation of Sublingual Microcirculation in Burn During Resuscitation
The adequacy of fluid resuscitation will be monitored in burn patients using microcirculation. Microcirculation camera will be placed on the base of the tongue and at different four quadrants.
- Trial name
- NCT05096559
- Testing
- Microcirculation cytocam
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Burns, Growth Factors, Combined Defect of
Keratinocyte Growth Factor and Cytokines in Burns.
KERATINOCYTE GROWTH FACTOR AND CYTOKINES IN SKIN BURNS. INTRODUCTION: Intense inflammatory responses are activated by burns that affect a large total body surface area.
- Conditions
- Burns, Growth Factors, Combined Defect of, Inflammation, Cytokine Storm
- Trial name
- NCT01302223
- Where
- Brazil
- Volunteers
- 8 people
- Sponsor
- Federal University of São Paulo
Burn
Polarity Action in Electrical Stimulation Transcutaneous Donors for Treatment Areas Burned Patients
To evaluate the effect of the polarity of the electric current in healing.
- Trial name
- NCT02679703
- Testing
- High voltage, Neuromuscular transcutaneous electrical stimulation (TENS), Control Group
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Burn Injury, Major Trauma
Study of Fibrinogen Metabolism During Severe Trauma and Burns
To study the fibrinogen metabolic changes in relation to coagulation disorder in patients with severe burns and trauma injuries. As a result of the burn or trauma injury breakdown of fibrinogen is accelerated.
- Trial name
- NCT00588796
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- United States Army Institute of Surgical Research
Burns Surgery
Antibioprophylaxis for Excision-graft Surgery in Burn Patient (A2B-TRIAL)
The indication of antibiotic prophylaxis in burn patients remains highly controversial and hasn't reached a consensus. The objective of antibiotic prophylaxis would be to reduce the risk of post-operative local and systemic…
- Trial name
- A2B (NCT04292054)
- Testing
- active intervention
- Where
- France
- Volunteers
- 506 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Burn Shock
Effect of Pre-emptive Intravenous Immunoglobulin (IVIG) on the Incidence of Septic Episodes in Pediatric Burn Patients
Effect of pre-emptive intravenous immunoglobulin administration on the incidence of septic episodes in pediatric burn patients: A randomized controlled study.
- Trial name
- NCT05134792
- Testing
- intravenous immunoglobulin
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neuropathic Pain
Comparison of Pain-Related Changes in Cerebral Blood Volume in Burn Patients With Neuropathic Pain
The investigators will observe increased or decreased CBV in patients with thermal injury compared with the CBV in healthy controls.
- Trial name
- NCT04125576
- Testing
- magnetic resonance imaging(MRI)
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hangang Sacred Heart Hospital
Thermal Hyperalgesia, Anxiety
A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients
Burn-related pain is severe and often difficult to manage. Healthcare workers struggle with keeping burn patients comfortable, especially when these patients undergo dressing changes of their burn wounds of their skin since these…
- Conditions
- Thermal Hyperalgesia, Anxiety, Pain
- Trial name
- NCT02336308
- Testing
- Ketamine
- Where
- United States
- Sponsor
- University of Colorado, Denver
Burns
The Effects of Robot-assisted Gait Training(RAGT) On Patients With Burn
This study aimed to elucidate the efficacy and investigate the mechanism of motor recovery after RAGT on patients with lower extremity burn.
- Trial name
- NCT03992547
- Testing
- Robot-assisted Gait Training
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Hangang Sacred Heart Hospital
Burns
Efficacy and Safety Study of Caldolor (Intravenous Ibuprofen) in Hospitalized Adult and Pediatric Burn Patients
The primary objective of this study of Caldolor administered to hospitalized adult and pediatric burn patients is to determine the efficacy of Caldolor on reducing fever when compared to placebo when administered every 6 hours…
- Trial name
- NCT00606489
- Testing
- Caldolor
- Where
- 5 sites in United States, India
- Volunteers
- 61 people
- Sponsor
- Cumberland Pharmaceuticals
Burns
Response of Muscle Mechanical Properties to Early Multi-angles Isometric Exercises in Acute Burn Patients
This study will be conducted to investigate the effect of early multi-angle isometric exercise on muscle properties in post-burn patients.
- Trial name
- ABP (NCT07832955)
- Testing
- isometric exercise program, conventional physical therapy
- Volunteers
- 40 people
- Sponsor
- Cairo University
Second Degree Burns
Heparin for the Treatment of Burn Wound Pain
Pain Associated with partial thickness burns (PTB) is very severe and distressing for the patients.Topical conventional treatment of superficial PTB wounds includes application of polyfax skin ointment plus lignocain gel twice a…
- Trial name
- NCT02497326
- Testing
- Polyfax & Lignocain gel or silvazine cream, Topical Heparin, Tramadol
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- King Edward Medical University
Scars, Hypopigmented Scar
Treatment of Hypopigmented Scars With Bimatoprost
Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR).
- Conditions
- Scars, Hypopigmented Scar, Hypopigmented Skin, Burn Scar
- Trial name
- NCT06122090
- Testing
- Bimatoprost, Saline
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute