Clinical trials: Burn Patients
Pain, Burn Injury
The Effect of Neurontin on Pain Management in the Acutely Burned Patient
Burn patients have extreme pain. Opioids are the main agents used for analgesia. We therefore propose a single center study to fruther assess the efficacy of neuropathic agents in controlling the pain associated with acute…
- Trial name
- NCT01265056
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Lucy A Wibbenmeyer
Spinal Cord Injuries, Polytrauma
Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Intensive Rehabilitation
The use of conditioning open-label placebo (COLP) will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury.
- Conditions
- Spinal Cord Injuries, Polytrauma, Burn Injury, Pain Management
- Trial name
- COLP (NCT03906721)
- Testing
- Oxycodone, Essential Oil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Spaulding Rehabilitation Hospital
Burns, Pharmacokinetics
Pharmacokinetics of Ceftolozane/Tazobactam in Patients With Burns
This study will help provide information about how patients with burn handle two antibiotics (ceftolozane and tazobactam) and use that information to guide dosing recommendations for these patients.
- Trial name
- NCT03002506
- Testing
- Ceftolozane/tazobactam
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Texas Tech University Health Sciences Center
Burns
Pilot Trial of Statin Use in Burn Patients
This is a 90 day study, with patients receiving either oral Rosuvastatin or placebo for up to 28 days. The study will assess the affect of statins administered soon after burn injury on C-reactive protein (CRP) levels, patient…
- Trial name
- BURNSTAT (NCT00978419)
- Testing
- Rosuvastatin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Burns
Effects of Therapy With Sulfamylon® 5% Topical Solution Compared to a Historical Control Group
The primary objective is to compare the effectiveness of treatment with Sulfamylon® solution as the initial topical moist dressing over meshed autografts following the initial graft procedure on preventing graft loss in a…
- Trial name
- NCT00634166
- Testing
- Sulfamylon® For 5 % Topical Solution, Topical Antimicrobial/Antifungal Medications
- Where
- 9 sites in United States
- Volunteers
- 220 people
- Sponsor
- Mylan Inc.
Burn
Use of Rotational Thromboelastometry (ROTEM) to Characterize Coagulation Abnormalities in Burn Patients
This is an interventional pilot study of 40 burn inpatients. Specific aims of the proposed pilot study are to use bedside blood analysis with rotational thromboelastometry (ROTEM) in severe burn patients to provide preliminary…
- Trial name
- NCT02388776
- Testing
- ROTEM
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Weill Medical College of Cornell University
Inhalation Injury, Pneumonitis
Prophylactic Bronchoscopy After Inhalation Injury in Burn Patients
The investigators hypothesize that the scheduled use of bronchoscopy on a regular basis after inhalation injury in burn patients will improve outcome by providing pulmonary hygiene, decrease the incidence of pneumonia, and detect…
- Conditions
- Inhalation Injury, Pneumonitis, Pneumonia
- Trial name
- NCT00997555
- Testing
- bronchoscopy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Hurley Medical Center
Complicated Skin and Soft Tissue Infection
Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections.
The purpose of this study is to evaluate the effects of Ceftaroline Fosamil versus Vancomycin plus Aztreonam in treatment of patients with complicated bacterial skin and soft tissue infections.
- Trial name
- NCT02202135
- Testing
- Ceftaroline fosamil, Vancomycin, Aztreonam
- Where
- 22 sites in Argentina, Brazil and 11 more
- Volunteers
- 4 people
- Sponsor
- Pfizer
Burns
Pharmacokinetic Response to BPI in Burns
The purpose of this study is to evaluate the safety of a protein called BPI that is naturally made by the body's white blood cells to fight infection.
- Trial name
- NCT00462904
- Testing
- BPI
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Texas Southwestern Medical Center
Burns
The Effect of Selenium Supplementation Among Pediatric Patients With Burns
The selenium status of children with major burns is suboptimal which may increase the incidence of infection. Se requirements during critical illness are not known.
- Trial name
- NCT00860379
- Testing
- Selenium1, Selenium2
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Shriners Hospitals for Children
Burns, Sedation
Dexmedetomidine Cardiovascular Safety in Pediatric Burn Patients
Dexmedetomidine is a sedative drug approved for adult patients, intubated, in intensive care units. We are studying whether this drug is cardiovascularly safe in pediatric patients who have recently been burned.
- Trial name
- NCT00697788
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital