Clinical trials: Burn Wound
Insulin Resistance, Hypermetabolism
Mechanisms of Improved Wound Healing and Protein Synthesis of Insulin and Metformin
Massive pediatric burns are associated with a persistent and sustained hypermetabolic response characterized by elevated levels of circulating catecholamine's, cortisol, and glucagon's, which can cause extreme muscle wasting…
- Conditions
- Insulin Resistance, Hypermetabolism, Hyperglycemia
- Trial name
- NCT01666665
- Testing
- Metformin, Sugar pill
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Stress, Well-being
Leading Well-being and the Psychosocial Working Environment - A Cluster-randomized Waitlist Controlled Trial
The design comprises a cluster, randomized waitlist controlled design. The goal of the study is to prevent stress and burnout in middle managers and employees in a hospital setting.
- Conditions
- Stress, Well-being, Burn Out
- Trial name
- Matterhorn (NCT05623371)
- Testing
- Training leaders in leading well-being and the psychosocial working environment, The offer of a webinar and written material
- Where
- Denmark
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Scars, Hypertrophic, Burn Scar
Microneedling Therapy With or Without Amnion Bilayer Sheeting on Scar Tissue
The aim of this study is to compare the outcome of microneedling therapy with or without amnion bilayer sheeting on post-burn hypertrophic scar tissue.
- Trial name
- NCT04995302
- Testing
- Microoneedling and Amnion Bilayer, Microoneedling
- Where
- Indonesia
- Volunteers
- 17 people
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Burn Wound, Second- or Third-degree Burn
MSCs for the Treatment of Burn Wounds
The goal of this study is to evaluate the capacity of allogenic mesenchymal stromal cells form bone marrow (BM-MSC) or adipose tissue(Ad-MSC) to induce wound healing in patients with burn wounds.
- Trial name
- NCT06103409
- Testing
- Implantation of allogeneic MSCs on burn wounds
- Where
- Venezuela
- Volunteers
- 50 people
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Burn Wounds - Partial Thickness (2nd Degree)
Field Shield Wound Dressing Study
This study is to compare the Field Shield Wound Dressing (FSWD) as a treatment for burn wounds to a standard of care burn wound dressing to evaluate healing, infection, pain/discomfort, and deepening of wound over time.
- Trial name
- NCT07337616
- Testing
- Field Shield Wound Dressing, Silverlon
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- KeriCure Medical
Burn
Use of Amnion on Partial Thickness Burns
To determine if Amnion, used on partial thickness burn injuries would provide an improvement in rate of healing, pain control and scarring as compared to standard medical treatments.
- Trial name
- Amnion (NCT00674999)
- Testing
- Amnion, Polysporin/Bacitracin/Mycostatin
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns
Study to Evaluate the Use of Tilapia Skin (Oreochromis Niloticus), in the Treatment of Burn Wounds
Randomised Clinical Study to evaluate the efficacy of Nile tilapia (Oreochromis niloticus) skin as an occlusive biological dressing, in the treatment of humans burn wounds.
- Trial name
- NCT03592498
- Testing
- Sulfadiazine, Silver, Skin of Nile tilapia
- Volunteers
- 63 people
- Sponsor
- Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
Burn, Thermal
StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements
About 70 participants will be enrolled. They will have complex skin defects because of burns caused by heat. The burns will: be on 3-49% of the participant's total body surface area (TBSA) require surgery for skin replacement…
- Trial name
- NCT03005106
- Testing
- StrataGraft Skin Tissue, Autograft
- Where
- 16 sites in United States
- Volunteers
- 71 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Burns
Phase 1 Healthy Volunteer Burn Therapy Study
This is a Phase 1, single-center, randomized, double-blind, placebo-controlled, first-in-human study to evaluate the safety of an investigational drug to treat burns. Participants will be healthy male and female adults.
- Trial name
- NCT06223009
- Testing
- cNP8
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Neomatrix Therapeutics, Inc.
Infections, Gram-Positive Bacterial, Abscess
Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)
Serious infections caused by resistant bacteria are becoming more of a medical problem throughout the world. One of the ways to deal with this problem is to develop new drugs that can control these bacteria.
- Conditions
- Infections, Gram-Positive Bacterial, Abscess, Burns, Cellulitis
- Trial name
- FAST (NCT00061633)
- Testing
- Telavancin, Vancomycin or antistaphylococcal penicillin
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Cumberland Pharmaceuticals
ARDS, Human, Burns
Predictive Factors, Demographics and Mortality for ARDS in Burn Patients
This retrospective study characterizes the clinical course and identifies four independent predictors of Acute Respiratory Distress Syndrome (ARDS) after burn injury (post-burn ARDS; pbARDS).
- Conditions
- ARDS, Human, Burns, Lung Diseases
- Trial name
- NCT03807232
- Volunteers
- 400 people
- Sponsor
- University of Zurich
Pediatric Nursing
The Effect of Digital and Classical Education Based on Planned Behavior Theory Given to Mothers in the Risk Group on Their Self-Efficacy in Identifying Safety Measures and First Aid for Home Accidents
Childhood home accidents are a significant health problem in our country and the world. Home accidents are more common in children aged 1-5, and cause temporary and permanent disabilities in deaths.
- Trial name
- Home Accidents (NCT06981416)
- Testing
- Digital education group, classical education group
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cancer
CH1701 for Prevention and Treatment of Radiation Burns
A combined Phase I\&II, randomized, double-blind, placebo-controlled clinical trial to evaluate efficacy and safety for prevention and treatment of radiation therapy burn of CH1701
- Trial name
- CH1701 (NCT04386343)
- Testing
- CH1701 for prevention and treatment of radiation burns., Safety assessment of CH1701
- Where
- Vietnam
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Vietlife Healthcare Corporation
Grafting, Skin, Burn
Fixation of Skin Grafts in Patients With Burns: Comparison Between Cyanoacrylate Glue and Skin Staples
Skin graft fixation is essential for the success of its survival. There are several common methods for skin graft fixation including sutures, skin staples and glue.
- Trial name
- NCT00363558
- Where
- Israel
- Volunteers
- 44 people
- Sponsor
- Rabin Medical Center
Burns Greater Than 20% BSAB, Burns
Microbiome Changes in Severe Burns
The purpose of the study is characterizing changes in the microbiome of severely-injured adult patients as they progress through stages of injury, reconstruction, and recovery from burns.
- Trial name
- Microbiome (NCT03130868)
- Testing
- Characterizing changes in the microbiome
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- HealthPartners Institute
Fat Burn, Diabetes Mellitus, Type 2
Physical Exercise, Diet, and Health in People With Type 2 Diabetes: Longitudinal Design of the EDUGUTION Study
This longitudinal design study is a continuation of the EDUGUTION project (Ref: PID2019-110063RA-I00; Clinical Trial: NCT05261373), a randomized controlled trial that was approved by the Clinical Research Ethics Committee of…
- Conditions
- Fat Burn, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Metabolism Disorder
- Trial name
- NCT06219850
- Testing
- No intervention
- Volunteers
- 120 people
- Sponsor
- University of Cadiz
Scars
Burn Scar Appearance After Treatment With Fractional Carbon Dioxide (CO2) Laser
The purpose of this study is to determine if fractional carbon dioxide laser treatment of a burn scar is a more effective method for improving the appearance of scars than the current available treatments.
- Trial name
- NCT00969215
- Testing
- Lumenis fractional carbon dioxide laser
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Moy-Fincher Medical Group
Hypertension, Heart Failure
LSFG-SKIN, Laser Speckle Flowgraphy
The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or…
- Conditions
- Hypertension, Heart Failure, Vascular Ischemia, Burns
- Trial name
- NCT03660618
- Testing
- laser speckle flowgraphy
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Full Thickness Skin Defects
The Safety of a Novel Acellular Dermal Template as Treatment for Burns and Scars
In this study the safety and feasibility of an acellular dermal template (Novomaix), combined with split thickness skin grafts, for use in patients with full thickness skin defects, is tested.
- Trial name
- NCT02164760
- Testing
- Novomaix dermal substitute in combination with STSG
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 13 people
- Sponsor
- Association of Dutch Burn Centres
Burn Scar Patients
Fractional Nonablative 1540 nm Laser Resurfacing for Burn Scars- A Randomised Controlled Trial
The objective was to evaluate the efficacy of 1540 nm fractional laser treatment of mature burn scars.
- Trial name
- NCT00689650
- Testing
- 1540 nm fractional laser
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital