Clinical trials: Burned Children
Burn Injuries
Mepilex Ag Versus Silver Sulfadiazine in Children and Adults With Burn Injuries.
The purpose is to compare time to healing using absorbent foam silver dressing (Mepilex Ag) compared to a silver sulfadiazine (SSD) 1% cream in the treatment of partial thickness burn injuries.284 in-patients in 8-12 centres in…
- Trial name
- NCT01439074
- Testing
- Mepilex Ag, Silver Sulphadiazine Ag cream
- Where
- 9 sites in China
- Volunteers
- 162 people
- Sponsor
- Molnlycke Health Care AB
Burns, Smoke Inhalation Injury
Helping Children's Centres to Enhance Home Safety
Many children have accidents, some are very serious and they are a major cause of death in children aged 1-4 years. Many accidents are preventable This study aims to find out the best way to help Children's Centres to provide…
- Trial name
- NCT01452191
- Testing
- Injury Prevention Briefing Plus facilitation, Injury Prevention Briefing
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Posttraumatic Stress Disorder, Depression
A Study of Sertraline to Prevent PTSD
The broad, long-term objectives of this proposal are to prevent the emergence of posttraumatic stress and depressive symptoms in children admitted for an acute burn, reconstructive surgery, or non-burn injury.
- Trial name
- NCT00182078
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Massachusetts General Hospital
Sleep, Burns
Differential Effects of Zolpidem Versus Ramelteon in Burned Children
To examine sleep changes following therapeutic drug interventions designed to promote sleep.
- Trial name
- Sleep3 (NCT00539110)
- Testing
- zolipidem, ramelteon
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shriners Hospitals for Children
Burns
Platelet-Rich Plasma (PRP) in Reconstructive Surgery on Children With Retractable Burn Sequelae on Extremities
Does the addition of Platelet-Rich Plasma (PRP) to release of burn contractures and skin graft on the limbs of children with retractable burn sequelae reduce the initial time of the compressive treatment and maintain or lower the…
- Trial name
- NCT00858442
- Testing
- With PRP
- Where
- Chile
- Volunteers
- 44 people
- Sponsor
- Corporation for the Aid of Burned Children
Burns
RES® Prepared With RECELL® Compared to Standard of Care Dressings of Partial-thickness Burns in Ages 1-16 Years
A prospective, parallel-arm, randomized (1:1) multicenter trial to demonstrate that RECELL treatment of partial-thickness burn injuries, can safely and effectively increase the incidence of Day 10 healing compared with a…
- Trial name
- NCT03626701
- Testing
- RES (Regenerative Epidermal Suspension) prepared using the RECELL® Autologous Cell Harvesting Device, Mepilex® Ag Wound Dressing, Conventional autografting (only when indicated)
- Where
- 9 sites in United States
- Volunteers
- 19 people
- Sponsor
- Avita Medical
Burn, Child
Virtual Reality Distraction for Procedural Pain Management and Anxiety in Children With Burn Injuries : A Pilot Study
Procedural pain is the most intense and often undertreated pain associated with burn injuries. The use of analgesics does not always provide optimal relief and is accompanied by several side effects.
- Conditions
- Burn, Child, Pain, Anxiety
- Trial name
- NCT02794103
- Testing
- Virtual Reality Distraction
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- St. Justine's Hospital
Burns
Evaluation of Hand Assessments in Children With Severe Hand Burns
This study is designed to see if some tests of hand movement, strength, and function are valid for children with burns.
- Trial name
- NCT00363675
- Testing
- Functional hand tests
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Massachusetts General Hospital
Burns, Wound Care
Comparison of Virtual Reality and Passive Distraction on Burn Wound Care Pain in Adolescents
Relief of severe burn wound care pain may require both medications to relieve pain and non-medication interventions,such as distraction. Little is known about distraction's effectiveness.
- Conditions
- Burns, Wound Care, Pain
- Trial name
- NCT01812655
- Testing
- Virtual Reality, Passive Distraction
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Stress, Psychological, Post-Traumatic Stress Disorder
Intervention to Reduce Stress in 0-5 Year Olds With Burns
The objectives of this study are to test and validate a simple, feasible intervention to reduce pediatric burn traumatic stress in 0-5 year old children and their parents.
- Conditions
- Stress, Psychological, Post-Traumatic Stress Disorder, Major Injury
- Trial name
- NCT00844896
- Testing
- DEF-only, DEF + COPE
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Massachusetts General Hospital
Thermal Burns
A Study to Evaluate the Efficacy and Safety of NexoBrid in Children With Thermal Burns Compared the Standard of Care
This study will be a two-arms study intending to demonstrate superiority of NexoBrid treatment over SOC in children with thermal burns.
- Trial name
- NCT02278718
- Testing
- NexoBrid, Standard of Care
- Where
- 36 sites in United States, Belgium and 12 more
- Volunteers
- 145 people
- Sponsor
- MediWound Ltd
Pain, Anxiety
The Use of Clonidine in Pain and Anxiety Associated With Acute Burn Injury in Children
Some of the children who suffer acute burn injury do not have adequate pain and anxiety management with the current regimen of scheduled opiates (morphine) and benzodiazepines (lorazepam).
- Trial name
- clonidine (NCT00580151)
- Testing
- clonidine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The University of Texas Medical Branch, Galveston