Clinical trials: Burning Mouth Syndrome
Burning Mouth Syndrome
The Role of Xerostomia in Burning Mouth Syndrome: Case - Control Study
Objectives: to evaluate xerostomia and salivary flow in patients with burning mouth syndrome (BMS) treated with amitriptyline before and after the use of antixerostomic topical medication.
- Trial name
- BMS (NCT01754740)
- Testing
- Uréia
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo General Hospital
Burning Mouth Syndrome
Neurogenic Mechanisms in Burning Mouth Syndrome
Burning mouth syndrome (BMS) is characterized by a bilateral burning sensation in the anterior tongue, hard palate and lips in the absence of any clinical or laboratory findings.
- Trial name
- BMS17 (NCT00875537)
- Testing
- Capsaicin oral gel 0.025%, Capsaicin oral gel 0.01%
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Pain
Assessment of Peripheral GABA Receptors for Local Pain Relief
The effect of peripheral GABAA receptor activation on pain and sensitivity in healthy human subjects has never been investigated.
- Trial name
- NCT02928328
- Testing
- GABA oral solution, Intramuscular GABA, Pain modulation
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Caffeine, Burning Mouth Syndrome
Caffeine vs. ALA in BMS Treatment. (BMS: Burning Mouth Syndrome. ALA: Alpha-Lipoic Acid.)
The aim of this study was to evaluate the efficacy of caffeine and alpha-lipoic acid in the treatment of burning mouth syndrome by symptom assessment with visual analogue scale.
- Trial name
- NCT06195137
- Testing
- Caffeine, Alpha Lipoic Acid
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Lu Jiang
Burning Mouth Syndrome
Botulinum Toxin in Burning Mouth Syndrome
The effect of botulinum neurotoxin type A intradermal injection in will be evaluated in 4 patients with clinical diagnosis of burning mouth syndrome involving the anterior two-thirds of the tongue and the lower lip for at least 6…
- Trial name
- NCT02964728
- Testing
- Botulinum Neurotoxin Type A, Normal saline
- Volunteers
- 6 people
- Sponsor
- Presidio Ospedaliero Garibaldi-Centro
Burning Mouth Syndrome
Effects of Photobiomodulation in Burning Mouth Syndrome
The main objective of this study is to assess the effects of Photobiomodulation with Low-level Laser Therapy to the pain management in Burning Mouth Syndrome patients, besides assessing their impact on the different aspects of…
- Trial name
- NCT04034849
- Testing
- Photobiomodulation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Rosa María López-Pintor Muñoz
Burning Mouth Syndrome
Comparison Between Two Treatments for Burning Mouth
Introduction: The management of patients with chronic burning mouth is a challenge in clinical dentistry. Objective: To compare the effect of Low Level Laser Therapy (LLLT) and Transcutaneous Electrical Nerve Stimulation (TENS)…
- Trial name
- NCT05816200
- Testing
- Low-Level Light Therapy, Transcutaneous Electric Nerve Stimulation
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Aphthous Stomatitis, Burning Mouth Syndrome
Evaluation and Treatment of Oral Soft Tissue Diseases
This study offers evaluation and treatment of patients with diseases of the mouth or systemic diseases that involve the mouth. The protocol is not designed to test new treatments; rather, patients will receive current standard of…
- Conditions
- Aphthous Stomatitis, Burning Mouth Syndrome, Lichen Planus, Mouth Disease
- Trial name
- NCT00001601
- Testing
- Electrocardiogram, Biopsies, Diagnostic imaging
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Burning Mouth Syndrome, Oral Mucosa Disease
Head Yuanshi Dian Therapy in Burning Mouth Syndrome
Burning mouth syndrome is one of the most common oral mucosal diseases in clinic. It is a chronic pain syndrome with extensive burning pain of oral mucosa as its main symptoms.
- Trial name
- NCT04481841
- Testing
- oryzanol + vitamin B2 (riboflavin) + vitamin E
- Where
- 3 sites in China
- Volunteers
- 290 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Burning Mouth Syndrome, Burning Mouth
Burning Mouth Syndrome Mouth Guard Prospective Study
This study will seek to test the effectiveness of a nonpharmacologic therapy for burning mouth syndrome (BMS). This nonpharmacologic therapy approach will be the fabrication a protective acrylic mouthguard for the maxillary arch…
- Trial name
- NCT04203134
- Testing
- Mouthguard
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Burning Mouth Syndrome, Taste Disorder
Burning Mouth Disorder (BMD) - A Neuropathic Pain Disorder
Oral burning can have a multitude of reasons. Recent neurophysiologic study results suggest that a primary burning mouth disorder (BMD) may be a peripheral and/or a central neuropathic disorder.
- Conditions
- Burning Mouth Syndrome, Taste Disorder, Orofacial Pain
- Trial name
- NCT00504387
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Markus R. Fussnegger
Burning Mouth Syndrome
Efficacy of Melatonin in Burning Mouth Syndrome (BMS)
The purpose of this study is to determine whether melatonin is effective in the treatment of burning mouth syndrome (BMS).
- Trial name
- BMS2013 (NCT02580734)
- Testing
- melatonin
- Volunteers
- 20 people
- Sponsor
- University of Milan
Burning Mouth Syndrome, Orofacial Pain
Burning Mouth Syndrome: Effects of Occlusal Splint Therapy
Burning Mouth Syndrome (BMS) causes chronic oral pain and significantly affects quality of life. Effective treatments are limited and often provide only temporary relief.
- Conditions
- Burning Mouth Syndrome, Orofacial Pain, Mouth Dryness
- Trial name
- NCT07344909
- Testing
- Essix splint
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Malmö University
Burning Mouth Syndrome
Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine and Western Medicine
This study is an open-label randomized controlled trial of the efficacy of the integration of Traditional Chinese medicine (TCM) and western medicine based on TCM syndrome differentiation.
- Trial name
- NCT04189367
- Testing
- Traditional Chinese Medicine, Western medicine
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Primary Burning Mouth Syndrome
Identification of Pathophysiological Pathways and Therapeutic Targets in Primary Stomatodynia by Salivary Metabolomics
Burning mouth syndrome (BMS) is defined by a chronic oral pain affecting especially postmenopausal women. Its physiopathology is still unknown and several hypotheses have been put forward to explain this syndrome, such as…
- Trial name
- SESAME (NCT04704128)
- Testing
- Salivic sample
- Where
- France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Burning Mouth Syndrome
A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome
This is a case control study of the association between burning mouth syndrome and sleep dysfunction. Cases will comprise of patients diagnosed with burning mouth syndrome at the UCSF oral medicine clinic.
- Trial name
- NCT00862576
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, San Francisco
Atrophic Glossitis, Burning Mouth Syndrome
HLA-DRB1 and HLA-DQB1 Genotyping for Autoantibody-positive and -Negative Patients With Atrophic Glossitis or Burning Mouth Syndrome
Patients with atrophic glossitis (AG) or burning mouth syndrome (BMS) are frequently encountered in the oral mucosal disease clinic.
- Trial name
- NCT01931293
- Testing
- Supplementation of vitamin B complex, C, B12, folic acid, Iron and Zinic
- Where
- Taiwan
- Volunteers
- 750 people
- Sponsor
- National Taiwan University Hospital
Burning Mouth Syndrome
Effect of Gluten Free Diet in Patients With Burning Mouth Syndrome
Gluten free diet (GFD) is now being tested in patients affected by schizophrenia, autism and multiple sclerosis, making GFD a possible therapeutic weapon not only for celiac disease or gluten sensitivity.
- Trial name
- NCT01867151
- Testing
- Gluten Free Diet, Normal Diet
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Burning Mouth Syndrome, Progesterone
Hormonal Status and Quality of Life in Female Postmenopausal Patients With Burning Mouth Syndrome
The aim of this study was to determine the level of salivary estradiol, progesterone and dehydroepiandrosterone in female postmenopausal women with and without burning mouth syndrome.
- Conditions
- Burning Mouth Syndrome, Progesterone, Dehydroepiandrosterone, Quality of Life
- Trial name
- NCT04535973
- Testing
- unstimulated saliva sample for hormone analysis, quality of life questionnaire
- Where
- Croatia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Burning Mouth Syndrome, Melatonin
Salivary Melatonin Levels and Sleep Quality in Patients With Burning Mouth Syndrome
Burning mouth syndrome is an idiopathic condition characterized by symptoms burning and / or pain of the oral mucosa with an orderly clinical finding. So far not found a unique way of treatment.
- Trial name
- NCT05309681
- Testing
- Epworth's sleepiness scale; unstimulated saliva sample
- Where
- Croatia
- Volunteers
- 45 people
- Sponsor
- University of Zagreb