Clinical trials: Burns Degree Second
Partial Thickness Burn of Hand
A Study to Evaluate the Efficacy of Cytal® Burn Matrix in the Management of Partial-Thickness Burns to the Hand
This is a randomized controlled trial (RCT) aimed at determining if use of Cytal® Burn Matrix in the management of partial-thickness burns to the hand shows improved wound healing times when compared to EZ-Derm Porcine Xenograft.
- Trial name
- NCT03598023
- Testing
- Cytal® Burn Matrix, EZ-Derm® Porcine Xenograft
- Sponsor
- Integra LifeSciences Corporation
Burn, Burn Contracture of Skin
Development and Clinical Study of Burn Wound Nursing Dressing Based on Sodium Hyaluronate Carbomer Composite Hydrogel
Development and clinical study of burn wound nursing dressing based on sodium hyaluronate carbomer composite hydrogel
- Conditions
- Burn, Burn Contracture of Skin, Burn Degree Second
- Trial name
- NCT07568600
- Testing
- sodium hyaluronate carbomer composite hydrogel
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Second Degree Burn
Evaluating the Cost-effectiveness, Efficacy, Safety and Tolerance of Mepilex® Ag Versus Silvadene®
The primary objective is to compare the incremental costs (direct and indirect) and benefits (healing outcomes, quality of life) of using foam silver dressing (Mepilex® Ag) to a Silver sulfadiazine 1% cream (Silvadene®) from the…
- Trial name
- NCT00742183
- Testing
- Mepilex, Silvadene
- Where
- 10 sites in United States
- Volunteers
- 100 people
- Sponsor
- Molnlycke Health Care AB
Second-degree Burn of Children
Evaluation of Efficacy and Safety of Ialuset Cream and Gauze in Second-degree Burns on Child
Observational retrospective monocentric study occured in the univeristy hospital center of Bensançon the department of pediatric surgery.
- Trial name
- NCT04124133
- Testing
- dressing with hyaluronic acid
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Laboratoires Genévrier
Partial-thickness Burn
PermeaDerm® vs. Mepilex-Ag® in Promoting Healing of Partial-thickness Burn Wounds
The purpose of this study is to compare the effectiveness of the wound dressings currently used at our institution for partial-thickness burn wounds: PermeaDerm® (PermeaDerm, Inc., Carlsbad, California, USA) and silver…
- Trial name
- NCT03613870
- Testing
- PermeaDerm, Mepilex Ag
- Sponsor
- The University of Texas Medical Branch, Galveston
Children, Acute Pain
Phoenixin and Pain in Pediatric Burn Patients
This prospective, controlled, observational study aims to investigate the relationship between phoenixin (PNX) levels and pain in pediatric burn patients.
- Conditions
- Children, Acute Pain, Burn Pain, Burn Degree Second
- Trial name
- NCT07858409
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Second- or Third-degree Burns
Allogeneic ADSCs and Platelet-Poor Plasma Fibrin Hydrogel to Treat the Patients With Burn Wounds (ADSCs-BWs)
The purpose of this study is to evaluate safety and efficacy of tissue engineered construct based on allogeneic cultured adipose-derived multipotent mesenchymal stromal cells (ALLO-ADSCs) and platelet-poor plasma fibrin hydrogel…
- Trial name
- ADSCs-BWs (NCT03113747)
- Testing
- ALLO-ASCs
- Where
- Ukraine
- Volunteers
- 20 people
- Sponsor
- A.A. Partners, LLC
Burn
A Study to Evaluate the Safety of ALLO-ASC-DFU in the Subjects With Deep Second-degree Burn Wound
This is a phase I study to evaluate the safety of ALLO-ASC-DFU for the treatment of deep second-degree burn wound patients. ALLO-ASC-DFU is a hydrogel sheet containing allogenic adipose-derived mesenchymal stem cells.
- Trial name
- NCT02394873
- Testing
- ALLO-ASC-DFU
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Anterogen Co., Ltd.
Burn Injury, Burn Scar
Tissue Quality of Integra vs. BTM Treated Burns
An observational analysis of Integra-treated burns and Novosorb Biodegradable Temporizing Matrix (BTM)-treated burns will be undertaken 12-36 months post final skin graft application by retrospectively analyzing the patient's…
- Conditions
- Burn Injury, Burn Scar, Burn Wounds - Partial Thickness (2nd Degree), Skin Grafting
- Trial name
- NCT06760611
- Sponsor
- Integra LifeSciences Corporation
Burns, Self Efficacy
Smartphone Assisted Self-management Education for Adult Burn Patient At Aftercare
Burn rehabilitation management is dependent on the patients themselves, non-treatment adherence may delay the optimal timing of burn rehabilitation and it may not be regained easily.
- Conditions
- Burns, Self Efficacy, Burn Second Degree, Burns Third Degree
- Trial name
- NCT06263296
- Testing
- Self Management Education
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Wounds and Injuries
Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing
This study is being performed to assess the effectiveness of Altrazeal(R) Transforming Powder Dressing (TPD) in patients with partial thickness burns compared to the current standard of care (SOC) dressing.
- Trial name
- NCT05424354
- Testing
- Altrazeal (R) Transforming Powder Dressing, Standard of Care burn dressing
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ULURU Inc.
Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn
Safety, Tolerability and Efficacy of Nefopam Cream in Burn Patients
Burn patients very commonly develop abnormal scars after injury which can be red, raised or elevated, painful and very itchy. They can prevent normal movement of hands and other joints and lead to ugly deformities which makes…
- Conditions
- Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn, Burn Degree Second
- Trial name
- NCT04685577
- Testing
- Nefopam
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Burns, Wound Healing
A Clinical Investigation to Evaluate Efficacy of Mepitel Ag in Partial Thickness Second Degree Burns
Approximately 55-65 subjects from 3-6 sites suffering from a burn injury covering 1-25% Total Body Surface Area (TBSA) will be evaluated providing they fulfill all inclusion and none of the exclusion criteria and have given a…
- Trial name
- NCT01636362
- Testing
- Mepitel Ag
- Where
- 6 sites in United States
- Volunteers
- 45 people
- Sponsor
- Molnlycke Health Care AB
Burns, Partial-thickness Burn
A Randomized Trial Evaluating EARLY Application of a Surfactant Dressing in Thermal Injury (EARLY)
The purpose of this study is to test the following hypotheses: 1. Early use of water-soluble surfactant dressing (WSD) on partial-thickness burn wounds will result in tissue salvage and reduce surgical burden. 2.
- Trial name
- EARLY (NCT04880655)
- Testing
- WSD, Dressed with bacitracin and petrolatum gauze
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Tennessee
Burn Wound and Skin Graft Healing
Healing of Burns and the Effect of Shockwave Therapy on the Recovery of Skin Grafts
The study is to review whether musculoskeletal shockwave therapy (ESWT) can speed up the healing of second-degree burns as well as skin-graft donor sites.
- Trial name
- NCT01242423
- Testing
- extracorporeal shockwave therapy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Unfallkrankenhaus Berlin
Burns, Pain, Burning
Effects of Applying Streaming Media on Reducing Pain in Patient With Second-degree Burn During Changing Dressing
During the acute phase of burn injuries, the focus for patients is primarily on wound pain and infection care. Patients often describe the pain during dressing changes as a sharp, stabbing sensation.
- Conditions
- Burns, Pain, Burning, Anxiety
- Trial name
- NCT06076031
- Testing
- Streaming Media
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital
Skin Burn Degree Second
Stem Cell Therapy to Improve Burn Wound Healing
This study will determine the safety of allogeneic stem cell therapy from healthy donors, for 2nd degree burn wounds of less than 20% Total Body Surface Area (TBSA), at four different dose levels.
- Trial name
- NCT02104713
- Testing
- Allogeneic (MSC's) Application to the Burn Wounds
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- E.Badiavas
Second or Third Degree Burns
Hypoalbuminemia in Burn Patients
The purpose of this study is to determine whether 5% human albumin solution, given to correct hypoalbuminemia, could improve organ dysfunction in burn patients as assessed by a change in the SOFA score from baseline to day 7 (or…
- Trial name
- Halburns (NCT01436292)
- Testing
- 5% human albumin solution (HAS)
- Where
- Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Second Degree Burns
Comparison of Amniotic Membrane Dressing and Aquacel®Ag in Second-degree Burns
To compare the outcome of amniotic membrane dressing versus Aquacel® Ag dressing with respect to the duration of healing in patients with second-degree burns within the local demographic setting.
- Trial name
- NCT07300137
- Testing
- preserved amniotic membrane dressing
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Patel Hospital, Pakistan
Burns, Second Degree Burn
4-Aminopyridine to Treat Skin Burns
Many patients suffer from traumatic burns and current treatments do not increase the regenerative potential of either skin grafts or the remaining uninjured skin.
- Conditions
- Burns, Second Degree Burn, Wounds and Injuries
- Trial name
- NCT06596434
- Testing
- Drug: 4-Aminopyridine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- John Elfar