Clinical trials: Burns Second Degree
Burn
A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-BI-101 Clinical Trial
This is an open-label follow up study to evaluate the safety for the subjects with ALLO-ASC-DFU treatment in phase 1 clinical trial(ALLO-ASC-BI-101) for 23 months.
- Trial name
- NCT03183622
- Testing
- ALLO-ASC-DFU
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Anterogen Co., Ltd.
Burn Injuries
Mepilex Ag Versus Silver Sulfadiazine in Children and Adults With Burn Injuries.
The purpose is to compare time to healing using absorbent foam silver dressing (Mepilex Ag) compared to a silver sulfadiazine (SSD) 1% cream in the treatment of partial thickness burn injuries.284 in-patients in 8-12 centres in…
- Trial name
- NCT01439074
- Testing
- Mepilex Ag, Silver Sulphadiazine Ag cream
- Where
- 9 sites in China
- Volunteers
- 162 people
- Sponsor
- Molnlycke Health Care AB
Partial-thickness Burn Wounds
Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns
The goal of this randomized controlled clinical trial is to determine whether use of Kericis Intact Fish Skin Graft (IFSG) can decrease the amount of autograft tissue needed for treatment of deep partial-thickness burns in…
- Trial name
- LOGI (NCT07326657)
- Testing
- Intact fish skin graft, autograft
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Kerecis Ltd.
Burn
A Study to Evaluate the Safety of ALLO-ASC-DFU in the Subjects With Deep Second-degree Burn Wound
This is a phase I study to evaluate the safety of ALLO-ASC-DFU for the treatment of deep second-degree burn wound patients. ALLO-ASC-DFU is a hydrogel sheet containing allogenic adipose-derived mesenchymal stem cells.
- Trial name
- NCT02394873
- Testing
- ALLO-ASC-DFU
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Anterogen Co., Ltd.
Partial-thickness Burn
Investigation of the Clinical Performance of Biatain Fiber Ag on Burns
The goal of this study is to test a new gelling fiber wound dressing with silver on patients with a partial thickness burn wound, which is infected or at risk of infection.
- Trial name
- NCT05824026
- Testing
- Gelling fiber wound dressing with silver
- Where
- 5 sites in United Kingdom
- Volunteers
- 52 people
- Sponsor
- Coloplast A/S
Burn Injury
A Clinical Trial to Evaluate the Safety and Efficacy of ALLO-ASC-DFU for Second Deep Degree Burn Injury Subjects
This clinical trial is a Phase II controlled, parallel, open-label trial, designed to test the efficacy and safety of ALLO-ASC-DFU and conventional therapy in Deep Second-degree burn wound subjects.
- Trial name
- NCT02619851
- Testing
- ALLO-ASC-DFU, Conventional Therapy
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Anterogen Co., Ltd.
Burn, Partial Thickness
Using Santyl or Bacitracin on Second Degree Burns
Subjects who have minor, second degree burns may be enrolled in this study. Subjects will receive either Santyl ointment or bacitracin ointment to apply to the burn until it heals.
- Trial name
- NCT01516463
- Testing
- Collagenase Santyl, Bacitracin
- Sponsor
- Healthpoint
Partial-thickness Burn
Effectiveness of KeraStat Gel for Improved Cosmesis of Partial Thickness Burns
A randomized, controlled, 30-subject, within-subject trial for examining the effectiveness of KeraStat Gel, as opposed to the institutional standard of care, silver sulfadiazine, in improving cosmesis of the healed wound.
- Trial name
- NCT03564795
- Testing
- KeraStat Gel, Silver Sulfadiazine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- KeraNetics, LLC
Acute Deep Partial Thickness Thermal Burns
Applying Platelet Rich Plasma (PRP) Gel to Acute Deep Partial Thickness Thermal Injuries
The study will examine the safety of using a concentration of proteins from a patient's own blood, referred to as platelet rich plasma or (PRP) and applying it to a second degree burn wound.
- Trial name
- NCT02169362
- Testing
- Autologous Platelet Rich Plasma (PRP) Gel (Magellan® Bio-Bandage™)
- Where
- 8 sites in United States
- Volunteers
- 36 people
- Sponsor
- Arteriocyte, Inc.
Burn, Burn Wounds - Partial Thickness (2nd Degree)
Phase II Clinical Trial of KJ101in the Treatment of Deep II Degree Burns
This multicentre, randomised, double-blind, dose-finding, active- and placebo-controlled Phase II clinical trial will evaluate the safety, efficacy, pharmacokinetic profile, and immunogenicity of KJ101 for the debridement of deep…
- Trial name
- NCT07025408
- Testing
- KJ101, Chymotrypsin
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Shanghai Bao Pharmaceuticals Co., Ltd.
Burns
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
To compare MW-III to Silvadene® Cream 1% (Silver Sulfadiazine) with respect to "time to healing" (≥95% re-epithelialization) of a partial thickness target thermal burn.
- Trial name
- NCT01297400
- Testing
- Investigational Drug, MW-III, Silvadene® Cream 1% [Silver Sulfadiazine]
- Where
- 6 sites in United States, Mexico
- Volunteers
- 60 people
- Sponsor
- Skingenix, Inc.
Wound Healing
An Open Single-centre Investigation Evaluating Efficacy in Second Degree Partial Thickness Burns Using a Silicone Contact Layer Containing Silver.
Approximately 10 subjects from one clinic having sustained a burn injury covering 1-25% or the Total Body surface Area (TBSA)and assessed as superficial partial-thickness or superficial deep-partial-thickness.
- Trial name
- NCT01734317
- Testing
- Mepilex Transfer Ag
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Molnlycke Health Care AB
Partial Thickness Burn of Hand
A Study to Evaluate the Efficacy of Cytal® Burn Matrix in the Management of Partial-Thickness Burns to the Hand
This is a randomized controlled trial (RCT) aimed at determining if use of Cytal® Burn Matrix in the management of partial-thickness burns to the hand shows improved wound healing times when compared to EZ-Derm Porcine Xenograft.
- Trial name
- NCT03598023
- Testing
- Cytal® Burn Matrix, EZ-Derm® Porcine Xenograft
- Sponsor
- Integra LifeSciences Corporation
Surgical Wound, Trauma Wound
Randomized Controlled Trial to Investigate Clinical Outcomes and Associated Costs When PermeaDerm is Used as Temporary Dressing for Surgical Wounds
The goal of this study is to compare the cost and clinical outcomes for two temporary dressings (Allograft and PermeaDerm) used in patients that need a skin graft to heal their wound.
- Conditions
- Surgical Wound, Trauma Wound, Autografts, Partial-thickness Burn
- Trial name
- NCT06750809
- Testing
- PermeaDerm Biosynthetic Wound Matrix, Frozen Human Cadaveric Allograft (FHCA)
- Where
- 13 sites in United States
- Volunteers
- 40 people
- Sponsor
- Avita Medical
Second Degree Burn
Evaluating the Cost-effectiveness, Efficacy, Safety and Tolerance of Mepilex® Ag Versus Silvadene®
The primary objective is to compare the incremental costs (direct and indirect) and benefits (healing outcomes, quality of life) of using foam silver dressing (Mepilex® Ag) to a Silver sulfadiazine 1% cream (Silvadene®) from the…
- Trial name
- NCT00742183
- Testing
- Mepilex, Silvadene
- Where
- 10 sites in United States
- Volunteers
- 100 people
- Sponsor
- Molnlycke Health Care AB
Burns
Oleogel-S10 Versus Standard of Care in Healing of Grade 2a Burn Wounds
The main goal of this phase III clinical trial is to show safety and efficacy of Oleogel-S10 in the acceleration of wound healing of grade 2a burn wounds.
- Trial name
- NCT01657292
- Testing
- Oleogel-S10 ointment, Octenilin® wound gel
- Where
- 9 sites in Germany, Sweden and 2 more
- Volunteers
- 61 people
- Sponsor
- Birken AG
Deep Partial-thickness Burn
StrataGraft® Skin Tissue Expanded Access at Specific Study Sites ( StrataCAT )
An autograft is a piece of skin taken from a healthy area of the body to be used to treat severe burns on another part of the same body.
- Trial name
- NCT04123548
- Testing
- StrataGraft skin tissue
- Where
- 10 sites in United States
- Volunteers
- 52 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Second-degree Burn of Children
Evaluation of Efficacy and Safety of Ialuset Cream and Gauze in Second-degree Burns on Child
Observational retrospective monocentric study occured in the univeristy hospital center of Bensançon the department of pediatric surgery.
- Trial name
- NCT04124133
- Testing
- dressing with hyaluronic acid
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Laboratoires Genévrier
Wound Infection
Phage Therapy for the Prevention and Treatment of Wound Infections in Burned Patients
The central aim of this trial is to investigate the safety and tolerability of Phage Cocktail-SPK as an adjunct to standard therapy for the prevention and treatment of burns susceptible to infection/or infected by S. aureus, P.
- Trial name
- NCT04323475
- Testing
- Bacteriophage cocktail spray, Xeroform
- Volunteers
- 12 people
- Sponsor
- Precisio Biotix Therapeutics, Inc.
Acute Burns
Using Autologous Platelet Rich Plasma (PRP) Gel to Treat Deep 2nd and 3rd Degree Burns
This study will demonstrate the safety of the application of autologous platelet rich plasma (PRP) gel following excision and autologous skin grafting of acute deep 2nd and 3rd degree burns.
- Trial name
- NCT01843686
- Testing
- Magellan®
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Arteriocyte, Inc.