Clinical trials: Butyrate
Gut Health
A Study to Evaluate the Effects of a Butyrate-Polyphenol Formulation on Gut Health and Associated Symptoms
The purpose of the study is to evaluate the efficacy of a butyrate/polyphenol formulation on modulation of the gut microbiome and gastrointestinal symptoms using questionnaires in individuals with self-reported gastrointestinal…
- Trial name
- NCT07371975
- Testing
- Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Gastro-Intestinal Disorder
A Pharmacokinetic Comparison of Three Butyrate Products
This study is a randomized, three-arm, interventional study of N=10 apparently healthy men. This study will quantify plasma butyrate responses to a single dose of three different butyrate products.
- Trial name
- NCT06700785
- Testing
- Lysine butyrate, Sodium Butyrate, Tributyrin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Radiodermatitis, Dermatitis, Radiation-Induced
Efficacy and Tolerability Evaluation of a Topical MD Based on SHBF in Management of Radiodermatitis.
This is a post marketing, interventional, randomized, single-center, prospective, controlled study, for the evaluation of the clinical performance and tolerability of a cream-based medical device (DermoRelizemaTM cream) in the…
- Trial name
- DRESDA (NCT04483856)
- Testing
- DermoRelizema cream, Dexeryl
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Relife Italia S.r.l.
EBV Lymphomas, Lympho-proliferative Diseases
Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies
The purpose of this study is to assess whether administration of Arginine Butyrate + ganciclovir/valganciclovir for up to three 21-day cycles is tolerable, and results in partial or complete responses in patients with EBV(+)…
- Trial name
- NCT00917826
- Testing
- Arginine Butyrate, Ganciclovir, Valganciclovir
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- HemaQuest Pharmaceuticals Inc.
Irritable Bowel Syndrome
The Efficacy of Sodium Butyrate and Probiotics in Patients With Irritable Bowel Syndrome
According to current IBS management guidelines, probiotic administration reduces IBS-associated symptoms and improves the quality of life.
- Trial name
- IBS-Plus (NCT05013060)
- Testing
- Probiotics and microcapsulated sodium butyrate, Maltodextrin
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Nordic Biotic Sp. z o.o.
Hypertensive Emergency
Safety and Efficacy Study of Clevidipine Butyrate Injection in Hypertensive Emergencies
The purpose of this study was to determine the efficacy and safety of clevidipine for treating Hypertensive emergencies（defined as systolic blood pressure >180 mmHg and/or diastolic blood pressure >120 mmHg, accompanied by acute…
- Trial name
- NCT04670809
- Testing
- Clevidipine Butyrate Injection, Ncardipine Hydrochloride Injection
- Where
- 2 sites in China
- Volunteers
- 262 people
- Sponsor
- Nanjing Yoko Biomedical Co., Ltd.
Hypertensive Emergency
A Study of Clevidipine Butyrate Injectable Emulsion in the Treatment of Hypertensive Emergency and Sub-emergency
A randomized, double-blind, active-compared phase Ш clinical trial to evaluate clevidipine butyrate injectable emulsion in the treatment of Hypertensive Emergency and Sub-emergency.
- Trial name
- NCT05783557
- Testing
- Clevidipine Butyrate Injectable Emulsion, Cleviprex®
- Volunteers
- 398 people
- Sponsor
- CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
Healthy, Gastrointestinal Discomfort
Effects of an Encapsulated Calcium Butyrate Dietary Supplement on Gut Health
The primary objective of this single-arm pilot study is to investigate the effects of an encapsulated calcium butyrate dietary supplement on gastrointestinal (GI) health outcomes in healthy adults, including GI symptom severity…
- Trial name
- NCT06397482
- Testing
- Encapsulated Calcium Butyrate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Eczema
Randomised, Double-blind, Placebo-controlled Study of Topical Clobetasone Butyrate 0.05% Cream in Subjects With Eczema for Two Weeks to Evaluate the Efficacy and Safety
This was a multicenter, randomised, double-blind, two treatment arms, vehicle (cream base) -controlled, parallel-group study in subjects with moderate to severe eczema (defined by investigators global assessment (IGA) score…
- Trial name
- NCT01567995
- Testing
- Clobetasone Butyrate 0.05% Cream, Vehicle (base cream)
- Where
- 7 sites in China
- Volunteers
- 240 people
- Sponsor
- GlaxoSmithKline
Hypercholesterolemia
Pharmacokinetics of Butyrate Tablet BKR-017
The purpose of this study is to evaluate the pharmacokinetic profile and systemic exposure of BKR-017 in individuals on statin therapy after a single dose and at steady state after seven days repeated twice daily dosing.
- Trial name
- NCT06556745
- Testing
- BKR-017
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- BioKier Inc.
Healthy
ButyraGen™, Short Chain Fatty Acids and Gut Microbiome
This study is being conducted to demonstrate short chain fatty acid (SCFA), specifically butyrate, generation in stool, blood and urine in response to oral intake of ButyraGen™.
- Trial name
- BG (NCT05601635)
- Testing
- ButyraGen™
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Gastrointestinal, Microbiota Balance
The Effects of a Postbiotic Supplement on Biomarkers of Gut Health
This study is a randomized, double-blind, two-arm, placebo-controlled trial of N=80 (40/arm) apparently healthy men and women between 18 and 65 years old to be recruited at a single investigational center in Northeast Ohio (i.e.…
- Conditions
- Gastrointestinal, Microbiota Balance, Microbiota, Cortisol
- Trial name
- NCT07527286
- Testing
- Postbiotic
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Verb Biotics LLC
Gut Health
Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms
The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms
- Trial name
- NCT06419231
- Testing
- Butyrate Formulation, Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Contact Dermatitis
Clinical Evaluation of T.R.U.E. TEST® : Safety and Efficacy
We propose an open, prospective, multi-center Phase III study to evaluate the diagnostic performance and safety of seven new T.R.U.E.
- Trial name
- NCT00640614
- Testing
- T.R.U.E. TEST® Skin Patch Test: Dose Response Allergens
- Where
- 5 sites in United States, Denmark
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Allerderm