Clinical trials: Butyrate
Irritable Bowel Syndrome
The Efficacy of Sodium Butyrate and Probiotics in Patients With Irritable Bowel Syndrome
According to current IBS management guidelines, probiotic administration reduces IBS-associated symptoms and improves the quality of life.
- Trial name
- IBS-Plus (NCT05013060)
- Testing
- Probiotics and microcapsulated sodium butyrate, Maltodextrin
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Nordic Biotic Sp. z o.o.
Irritable Bowel Syndrome (IBS), Healthy
Mode of Action of Butyrate in the Human Colon
Butyrate has recently gained attention as an important microbial compound in human colon health. Several diseases, including Irritable Bowel Syndrome (IBS), have been linked with a loss of butyrate in the colon resulting in the…
- Trial name
- NCT05249023
- Testing
- Sodium butyrate bolus
- Where
- Sweden
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Type1diabetes
Butyrate Adjuvant Therapy for Type 1 Diabetes
The investigators are interested to evaluate the effect of BKR-017 (colon-targeted 500 mg butyrate tablets) as adjuvant therapy on metabolic control in type 1 diabetes (TID) subjects.
- Trial name
- NCT03999853
- Testing
- BKR-017
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Health, Subjective, Healthy
RIGHTWHEY - Responders In Gut HealTh Markers Using Fermented WHEY
This 8-week intervention will investigate the effect of daily consumption of a fermented whey concentrate on the short-chain fatty acid profile of faeces in healthy individuals.
- Conditions
- Health, Subjective, Healthy, Microbial Colonization
- Trial name
- RIGHTWHEY (NCT03844152)
- Testing
- Fermented whey concentrate
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Obesity, Childhood
Effects of Butyrate Against Pediatric Obesity
Worldwide obesity is a public health concern that is defined by the World Health Organization as abnormal or excessive fat accumulation that may impair health.
- Trial name
- BAPO (NCT04620057)
- Testing
- butyrate
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Federico II University
Healthy
Effects of the Short-Chain Fatty Acids-Targeted Dietary Interventions on the Selected Autonomic Functions in Humans
Recent data feature short-chain fatty acids (SCFAs), products of gut microbial fermentation, as modulators of the blood pressure of the host.
- Trial name
- NCT06851039
- Testing
- Potato starch supplementation, Sodium butyrate supplementation, Accessible starch supplementation
- Where
- Poland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Graft Versus Host Disease, Postbiotics
Intestinal Microbiome-based Research for the Prevention of Acute GVHD
Hematopoietic stem cell transplantation consists of preconditioning chemotherapy, stem cell infusion, and engraftment of hematopoietic stem cells.
- Conditions
- Graft Versus Host Disease, Postbiotics, Butyrate
- Trial name
- NCT05808985
- Testing
- sodium butyrate
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Soonchunhyang University Hospital
EBV Lymphomas, Lympho-proliferative Diseases
Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies
The purpose of this study is to assess whether administration of Arginine Butyrate + ganciclovir/valganciclovir for up to three 21-day cycles is tolerable, and results in partial or complete responses in patients with EBV(+)…
- Trial name
- NCT00917826
- Testing
- Arginine Butyrate, Ganciclovir, Valganciclovir
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- HemaQuest Pharmaceuticals Inc.
Overweight and Obesity
Plasma SCFAs After Fermentable Cereal Fibres - A Postprandial Study
Circulating SCFAs reflect the net effect of what is produced in the large intestine from dietary fibre fermentation, bioavailability after considerable absorption by the enterocytes and in the liver and the elimination.
- Trial name
- FIFERM (NCT05443828)
- Testing
- Breakfast Control Meal, Breakfast Test Meal
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University