Clinical trials: C Section
Anesthesia, Obstetrical
Subarachnoid Bupivacaine in Obese Patients Undergoing Cesarean Delivery
This study evaluates the effect of subarachnoid hyperbaric bupivacaine on mean arterial blood pressure (MAP) of pregnant patients with obesity undergoing cesarean section half of the patients will receive subarachnoid hyperbaric…
- Trial name
- NCT04205344
- Testing
- Bupivacaine 5 mg, Bupivacaine 10 mg
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Civil de Guadalajara
Uterine Scar
Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars
The purpose of this study is to evaluate the safety of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of uterine scars by a prospective, single-center, open, and single-arm clinical trial.
- Trial name
- NCT03181087
- Testing
- Umbilical cord MSCs
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Elective Cesarean Section
Antibiotic Prophylaxis Before Surgery Versus After Cord Clamping in Elective Cesarean Delivery - a Double-blind, Prospective, Randomized Placebo-controlled Trial
In this prospective, randomized, placebo controlled trial the investigators were able to demonstrate the usefulness of prophylactic cefazolin in elective caesarean section versus placebo, irrespective of the timing of…
- Trial name
- NCT01248078
- Testing
- Keflex, saline solution
- Where
- Austria
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Cesarean Section; Infection, Scar
Evaluation of Wound Infection Rates and Cosmetic Results of Different Suture Materials in Cesarean Skin Incision
Our primary aim is to determine the most beneficial suture in order to reduce complications due to skin incision in common surgeries such as cesarean section, and our secondary aim is to evaluate the suture material used in terms…
- Trial name
- NCT06119113
- Testing
- Evaluation of the wound infection at the 10th day post-op check-up among all groups, Evaluation of the cosmetic results of the incision line at the 2nd month post-op check-up among all groups, Evaluation of the cosmetic results of the incision line at the 6th month post-op check-up among all groups
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ayşenur Çalış Özbayram
Pregnancy
Dermabond Skin Adhesives vs Skin Staples for Closure of Repeat Cesarean Section Skin Incisions
The use of dermabond skin adhesive vs. skin staples for the closure of repeat c-section incisions.
- Trial name
- NCT00505856
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Pregnant Women, Cesarean Section
Evaluation of the Absence of Intraoperative Bladder Catheterization in Case of Planned Cesarean Section
The hypothesis of this trial is that the absence of systematic bladder catheterization in patients performing spontaneous urination in the hour preceding the planned cesarean section under spinal anesthesia would not lead to more…
- Trial name
- C2S (NCT06357546)
- Testing
- Spontaneous urination during the hour before caesarean section., Systematic bladder catherization during caesarean section.
- Where
- 2 sites in France
- Volunteers
- 550 people
- Sponsor
- University Hospital, Montpellier
Respiratory Distress Syndrome, Newborn
Antepartum Betamethasone Treatment for Prevention of Respiratory Distress in Infants Born by Elective Cesarean Section
This is a randomized, multicenter, double blind, placebo controlled trial of betamethasone versus a placebo given prior to the mothers at term and near term gestation (>34 and <40 weeks of gestation) who are scheduled to undergo…
- Trial name
- NCT00139256
- Testing
- Betamethasone
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Emory University
Cesarean Section; Complications, Wound, Infection (Following Delivery)
Patient Reported Experiences and Outcomes Associated with Standard C-Section Wound Closure Versus STRATAFIX/DERMABOND PRINEO Wound Closure (CS-PREO)
The aim of the study is to compare outcomes between patients receiving standard C-section wound closure compared to a wound closure bundle that includes Stratafix sutures and Dermabond PRINEO.
- Trial name
- CS-PREO (NCT06614829)
- Testing
- Stratafix Suture, DERMABOND PRINEO
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- North York General Hospital
Cesarean Section; Dehiscence, Uterine Bleeding
Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial
The objective of this randomized monocentric study is to assess potential variations in the incidence and severity of isthmocele morbidity among women undergoing cesarean section with either single or double-layer closure of the…
- Conditions
- Cesarean Section; Dehiscence, Uterine Bleeding, Uterus; Scar, Uterus Abnormal
- Trial name
- NCT06308172
- Testing
- Hysterotomy closure
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Pruritus, Pregnancy Related
Treatment of Pruritus With Intramuscular Promethazine
Neuraxial narcotics are commonly used in obstetric patients for cesarean delivery to help with pain control over the first 24 hours after the surgery.
- Trial name
- NCT04805073
- Testing
- Promethazine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Florida
Postoperative Nausea and Vomiting
Comparison Between Intravenous Ondanosteron and Metclopromide Versus Ondanesteron and Dexamethasone Effects on the Prevention of Postoperative Nausea and Vomiting in Cesarean Section
The goal of this clinical trial is to prevent intraoperative nausea and vomiting (IONV) and postoperative nausea and vomiting (PONV) through comparing the efficacy of combination ondanosteron plus metclopromide versus…
- Trial name
- NCT06810531
- Testing
- Ondanesterone plus dexamethasone combination, ondanesterone plus metoclopramide combination
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Aiman Al-Touny
Postoperative Pain Control
Ultrasound-guided TAP Block Vs Local Wound Infiltration for Analgesia After Cesarean Section.
Adequate pain control after cesarean delivery is a major concern for both parturients and obstetrician, and it usually comprise a combination of systemic and regional techniques.
- Trial name
- NCT04711096
- Testing
- Ultrasound-guided transversus abdominis plane (TAP) block 0.25% bupivacaine.
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Anesthesia
Impact of Pre-spinal Atropine on Post Spinal Hemodynamics and Cardiac Output Measured by Electrical Cardiometry in Caesarean Delivery
Cesarean section is one of the most commonly performed surgical procedures; approximately 80-90% of elective cesarean sections are conducted using spinal anesthesia .
- Trial name
- NCT05658380
- Testing
- atropine, Isotonic saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Anesthesia
Comparison of 3 Different Density Levobupivacaine Solutions + Fentanyl for Spinal Anaesthesia for Caesarean Delivery.
The investigator's aim is to compare the efficacy of 3 levobupivacaine solutions with different density on spinal anesthesia for caesarean delivery.
- Trial name
- NCT03956303
- Testing
- Chirocaine %0.5, Chirocaine Heavy 40, Chirocaine Heavy 60
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Spinal Anesthesia
Minimum Effective Dose of Ropivacaine for Spinal Anesthesia for Cesarean Delivery
Ropivacaine is one of commonly used anesthetics for spinal anesthesia. Usually L2-3 or L3-4 intervertebral space is chosen for spinal anesthesia.
- Trial name
- NCT02565303
- Testing
- Intervertebral space, Ropivacaine
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai 6th People's Hospital
Post Cesarean Section Pain
Rectus Muscle Re-approximation at Cesarean Delivery
We include in our study 200 pregnant women, primigravidas, at term who underwent elective lower segment Cesarean section for the first time among the age group of 20 - 35 years.
- Trial name
- NCT03296969
- Testing
- cesarean section, Rectus muscle approximation
- Volunteers
- 200 people
- Sponsor
- Cairo University
Thrombophilia
Thromboelastography to Assess Age-Related Coagulation Differences in Patients Undergoing Cesarean Delivery
The purpose of the study is to assess potential age-related differences on coagulation profile of patients undergoing Cesarean Section, using thromboelastography (TEG).
- Trial name
- NCT01416454
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cesarean Section Complications, Hemodynamic Instability
Norepinephrine in Caesarian Section
Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion.
- Conditions
- Cesarean Section Complications, Hemodynamic Instability, Foetal Stress
- Trial name
- NCT05264870
- Testing
- Norepinephrine
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Pain
Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section
For post-Cesarean analgesia, the investigators will compare the efficacy of single-shot epidural preservative free morphine with a continuous epidural fentanyl infusion.
- Trial name
- NCT01362998
- Testing
- Preservative free morphine, Fentanyl
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Goodman, Evan, M.D.
Labor
The Endocannabinoid System in Human Gestational Tissues in Labor
The purpose of this research study is to determine if the endocannabinoid (a biological system) plays a role in the labor process.
- Trial name
- NCT03752021
- Testing
- Myometrial Sampling
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
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