Clinical trials: C Section
Cesarean Delivery, Postpartum Comfort
Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks.
- Conditions
- Cesarean Delivery, Postpartum Comfort, Postpartum Pain, Post-operative Pain
- Trial name
- PACESS (NCT07102641)
- Testing
- Acetaminophen, NSAID (Ketorolac/Ibuprofen)
- Where
- United States
- Volunteers
- 825 people
- Sponsor
- Thomas Jefferson University
Microbiota, Postoperative Recovery
The Effect of Oral Gan Shuangbi During the Perinatal Period on the Recovery of Intestinal Function After Cesarean Section in Pregnant Women- A Multicenter, Double-blind, Randomized Controlled Clinical Trial
This study aims to evaluate the effect of probiotics 7 days before cesarean section (CS) on postoperative recovery and the change of gut microbiota in pregnant women.
- Trial name
- NCT06347770
- Testing
- Probiotic Blend Oral Tablet
- Where
- 2 sites in China
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Zhe Li
Uterine Scar
Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars
This is a single center, randomized, double blind, placebo controlled study to evaluate the safety and efficacy of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of caesarean section uterine…
- Trial name
- NCT02968459
- Testing
- Umbilical cord MSCs, 0.9% Saline
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Postnatal Pulmonary Adaptation, Cesarean Section
Inhaled Salbutamol in Elective Caesarean Section
The lungs of the fetus are filled with fluid and it is essential that fetal lung fluid is cleared at birth. This process is mediated through the activation of airway epithelial sodium channels (ENaC).
- Trial name
- SAISTY (NCT01978418)
- Testing
- salbutamol
- Where
- Finland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sture Andersson
Contraception Behavior
Utility of Immediate Post Placental Insertion of Intrauterine Device During Cesarean Delivery
Iraq is a country that ranks 33rd around world population growth rate. Meanwhile it is one of the counties in the middle east with the highest fertility rate, In addition to the considerable number of unintended pregnancy mainly…
- Trial name
- NCT04136613
- Testing
- Copper Intra uterine contarceptive device ( Cu-T 380A)
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- Taghreed Alhaidari
Microbial Colonization, Antibiotic Side Effect
Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome
In this study, investigators seek to determine whether the timing of antibiotics given to mothers during an elective C-section affects the composition of their infant's gut microbiome.
- Conditions
- Microbial Colonization, Antibiotic Side Effect, Cesarean Section Complications
- Trial name
- CSBabyBiome (NCT06030713)
- Testing
- Cefazolin
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Intraoperative Pain
Sensory Stimuli During Cesarean Delivery
During a cesarean delivery (C-section), most patients are awake and receive spinal or epidural anesthesia to block pain from the lower body.
- Trial name
- PIONEER-MC (NCT07340970)
- Testing
- Patient-initiated request for pharmacological intervention during cesarean delivery
- Where
- Canada
- Volunteers
- 1,005 people
- Sponsor
- University of British Columbia
Pain, Postoperative, Depression, Postpartum
Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1)
The purpose of this study is to identify a tolerable dose for postpartum ketamine infusion using a maximum tolerated dose (MTD) 3+3 design.
- Trial name
- NCT05907213
- Testing
- Ketamine (Ketalar) Dose Level 1, Ketamine (Ketalar) Dose Level 2, Ketamine (Ketalar) Dose Level 3
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Respiratory Aspiration, Pregnancy
Gastric Sonography in the Fasted Term Pregnant Patient for Elective Cesarean Delivery
Food residue in the stomach of patients scheduled to have surgery is considered a major risk factor for pulmonary aspiration of gastric contents.
- Trial name
- NCT01980121
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy
Maternal Microcirculation & SDF Imaging
This is a study of pregnant women undergoing a cesarean delivery. It will compare their microcirculation before and after the anesthetic. Microcirculation means blood flow to the extremely small blood vessels in the body.
- Trial name
- NCT02376192
- Testing
- Initial MicroScan® (Microvision Medical) SDF Measurement, Spinal Anesthesia- Bupivacaine, Comparative MicroScan® (Microvision Medical) SDF Measurement
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- IWK Health Centre
Cesarean Section; Dehiscence, Postoperative Pain
The Effect of Music Postoperative Period
This randomized controlled trial aimed to evaluate the effects of music listening on anxiety and pain among women following cesarean delivery. A total of 110 women who had undergone cesarean section were included.
- Trial name
- EMPP (NCT07164521)
- Testing
- Music Listening (Relaxing Classical Music)
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Pain, Postoperative, Ambulation Difficulty
Comparison of FAUCS vs. Misgav Ladach
This study aims to compare two techniques for performing a cesarean delivery: Misgav Ladach versus French Ambulatory Cesarean Section (FAUCS).
- Trial name
- NCT03812406
- Testing
- French Abulatory Cesrean Section, Misgav-Ladach
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Postoperative Pain, Caesarean Section
Intraperitoneal Hydrocortisone for Postoperative Pain and CRP Following Caesarean Section
The purpose of this study is to evaluate the clinical efficacy of intraperitoneal hydrocortisone 100 mg administration in reducing postoperative pain and inflammatory response in patients undergoing elective Caesarean section…
- Conditions
- Postoperative Pain, Caesarean Section, Peritoneal Inflammation
- Trial name
- NCT07892547
- Testing
- hydrocortisone, Nornal Saline
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Raditsya Mada Gautama, MD
Evaluate to Effects of Two Antiseptic Products and Showering
CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE
The study was planned to evaluate the effects of two most commonly used antiseptic products and showering on the healing process, such as wound healing and postoperative maternal comfort in cesarean section.
- Trial name
- NCT05953714
- Testing
- incision side cleaning with antiseptic products
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Sakarya University
Postpartum Hemorrhage
Four Different Methods of Performing External Aortic Compression After Caesarean Section
After childbirth, bleeding from the uterus occurs, which can quickly become very profuse if the uterus does not contract. Annually, around 80000 women die because profuse bleeding associated with childbirth, mainly in low -and…
- Trial name
- KEXAC (NCT06157307)
- Testing
- Aortic compression
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Transversus Abdominis Plane (TAP) Block, Wound Infiltration
Ultrasound-guided Transversus Abdominis Plane Block Versus Local Wound Infiltration (TAP_WI)
The goal of this clinical trial is to learn if transversus abdominis plane (TAP) block will reduce the cumulative opioid consumption compared to local wound infiltration (WI).
- Conditions
- Transversus Abdominis Plane (TAP) Block, Wound Infiltration, Pain Score (VAS), Opioid Analgesia
- Trial name
- TAP (NCT06627946)
- Testing
- TAP group
- Where
- Bhutan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Cesarean Section
Use of Cesarean Birth at Private Health Facilities in Lilongwe and Blantyre, Malawi
The purpose of the research study is to collect preliminary data to which future outcomes after implementing quality improvement projects or research will be compared.
- Trial name
- NCT04442997
- Where
- 3 sites in Malawi
- Volunteers
- 260 people
- Sponsor
- University of Colorado, Denver
Dehydration
Impact of Oral Carbohydrate Consumption Prior to Cesarean Section
For more than 15 years, traditional fasting regimens prior to scheduled surgeries have been called into question, yet prolonged preoperative fasting remains common practice.
- Trial name
- NCT02684513
- Testing
- Oral Carbohydrate Beverage, Rehydration beverage
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Florida
Postoperative Pain
Quadratus Lumborum Block vs Intrathecal Morphine for Post-Cesarean Analgesia
İn this study, planned to compare the post-operative analgesic efficacy of Intrathecal Morphine Administration and anterior Quadratus lumborum Block in elective cesarean section operations.
- Trial name
- NCT06612424
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, İNTRATECHAL MORPHİNE GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Postoperative Pain, Cesarean Section
Intrathecal Morphine 75 mcg Versus 100 mcg for Post-Cesarean Analgesia: A Randomized Double-blind Trial
This study evaluates the efficacy and safety of two different doses of intrathecal morphine (75 mcg versus 100 mcg) for postoperative analgesia in patients undergoing elective cesarean delivery under spinal anesthesia.
- Conditions
- Postoperative Pain, Cesarean Section, Obstetric Anesthesia
- Trial name
- ITM-CESAREAN (NCT07516717)
- Testing
- Intrathecal Morphine
- Where
- Venezuela
- Volunteers
- 240 people
- Sponsor
- Hospital Universitario de Caracas
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