Clinical trials: C-Section
Cesarean Section
Closing Uterine Incision During C-section Using Barbed Suture (Stratafix) or Vicryl Suture.
A Randomized prospective single blinded trial. The investigator seek to evaluate the surgical outcome of Stratafix barbed suture compared to standart Vicryl sutures in reducing the suturing time during C-Section.
- Trial name
- NCT03159871
- Testing
- Stratafix suture, Vicryl suture
- Where
- Israel
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Cesarean Section (MeSH: D002585), Postoperative Pain After Cesarean Section
Esketamine Combined With Transcutaneous Electrical Acupoint Stimulation on Postoperative Recovery Quality After Elective Cesarean Section
This study is a prospective randomized controlled trial aimed at evaluating whether the combination of esketamine and transcutaneous electrical acupoint stimulation (TEAS) can improve the quality of postoperative recovery in…
- Conditions
- Cesarean Section (MeSH: D002585), Postoperative Pain After Cesarean Section, Enhanced Recovery After Surgery
- Trial name
- NCT07916051
- Testing
- Esketamine, Active TEAS, Normal Saline
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cesarean Section Complications
Reducing Blood Loss During Cesarean Myomectomy With Tranexamic Acid
This study was a double-blinded randomized controlled study conducted at Aswan University, Egypt from January 2018 to January 2020.
- Trial name
- TA (NCT03505502)
- Testing
- IV tranexamic acid
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Aswan University Hospital
Cesarean Section
Diclofenac vs. Ropivacaine for Cesarean Section
A prospective, randomized, double blind study designed to investigate analgesic efficacy of wound infusion using diclofenac or ropivacaine following Cesarean section performed via a Pfannenstiel incision.
- Trial name
- NCT00801528
- Testing
- Ropivacaine, Diclofenac, Water for injection
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Meir Medical Center
Hypotension
Diastolic Performance and Norepinephrine in Spinal-Induced Hypotension for Cesarean Delivery
Background and rationale: The best agent to prevent spinal-induced hypotension is still uncertain but norepinephrine showed fewer effects on heart rate and cardiac output.
- Trial name
- NORA-CS (NCT04560634)
- Testing
- Norepinephrine, ClearSight®, Edwards Lifescience, Irvine, CA
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Postoperative Pain
Quadratus Lumborum Block vs Tranversus Abdominis Plane Block for Cesarean Section
The Quadratus Lumborum block (QLB) was first described by Blanco in 2007. The main advantage of QLB compared to the Transversus Abdominis Plane block (TAP) is the extension of local anesthetic agent beyond the TAP plane to the…
- Trial name
- NCT02489851
- Testing
- Quadratus Lumborum block, Tranversus Abdominis plane block
- Where
- United Arab Emirates
- Volunteers
- 76 people
- Sponsor
- Corniche Hospital
Obesity, Labor Induction
Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial
Obese pregnant women (BMI ≥ 30 kg/m2) are more likely than their normal-weight counterparts to require induction of labor because of increased rates of obstetric complications including pregnancy related hypertensive disorders…
- Conditions
- Obesity, Labor Induction, Cesarean Delivery
- Trial name
- CROWN (NCT02639429)
- Testing
- Vaginal Misoprostol, Foley Balloon + Vaginal Misoprostol
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Cesarean Section
Perineuraxial Anesthesia Fluid Management and Infant Neurobehaviors
Early change in neurobehavior is strongly associated with the intelligence development of children. Previous studies reported that cesarean section itself could influence the later development of children.
- Trial name
- PAFUMIN (NCT00987701)
- Testing
- Ringer's Lactate, Six percent hydroxyethyl starch
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Nanjing Medical University
Cesarean Section
Misoprostol+Oxytocin vs. Carbetocin in CS
This prospective randomized double-blind clinical trial will be conducted at Ain-Shams University Maternity Hospital, Cairo, Egypt. Patients eligible for elective lower segment cesarean section will be randomized to 2 groups.
- Trial name
- CS (NCT02786992)
- Testing
- Misoprostol, Oxytocin, Carbetocin
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Ain Shams University
Glycopyrrolate, Post-spinal Hypotension
Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia
This is prospective randomised double blind study conducted in parturients planned for non-elective caesarean section under spinal anaesthesia.
- Conditions
- Glycopyrrolate, Post-spinal Hypotension, Effect of Drug, Hemodynamic Instability
- Trial name
- NCT04401345
- Testing
- Glycopyrrolate 0.2 MG/ML, Normal saline
- Where
- Nepal
- Volunteers
- 258 people
- Sponsor
- Rajesh Deshar
Effect of Drug
Determination of Blood Loss After CS
Comparing betweeen tranexamic acid plus oxytocin and oxytocin alone in their efficacy in reducing blood loss following CS
- Trial name
- NCT04549012
- Testing
- Tranexamic acid, Oxytocin
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Microbial Colonization
Restoration of the Gut Microbiome After Cesarean Section
This study aims to develop a therapy for restoring the gut microbiome in infants born via CS. The Study will conduct a randomized, placebo-controlled feasibility trial to assess the ability of microbiome restoration by FMT and…
- Trial name
- RestoreGut (NCT06264219)
- Testing
- Microbiome restoration - FMT, Microbiome restoration - FVT, Vaginal birth, untreated control
- Where
- 2 sites in Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jakob Stokholm
Pregnancy
Effectiveness of 10% Lidocaine on Relieving Pain Caused by Intravenous Intubation
The goal of this clinical trial is to learn if 10% Lidocaine spray can reduce local pain caused by intravenous (IV) intubation among women.
- Trial name
- NCT07212192
- Testing
- Lidocain spray, Sterilized saline solution
- Where
- Vietnam
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Phenikaa University
Breech Presentation
Comparison of Efficiency Between Practicing of Knee Chest Position and External Cephalic Version in Cases of Breech Presentation.
Background: The incidence of breech presentation in pregnant women is 4%. The situation can be treated by two methods. The first is a version of the fetus from breech presentation to head presentation, which can be performed in…
- Trial name
- NCT02167841
- Testing
- Knee-Chest Position
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Supine Hypotensive Syndrome, Cesarean Section Complications
Arm and Ankle Blood Pressure Cuffs During C-Section
This is a single center prospective self-control study to validate the effectiveness of left uterine displacement after subarachnoid block (SAB) with simultaneous measurements of blood pressure (BP) on the arm and left ankle…
- Conditions
- Supine Hypotensive Syndrome, Cesarean Section Complications, Anesthesia Complication
- Trial name
- NCT04934995
- Testing
- Blood Pressure Cuff
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Opioid Use, Pain, Postoperative
Ibuprofen and Acetaminophen Versus Ibuprofen and Acetaminophen Plus Hydrocodone for Analgesia After Cesarean Section
Postpartum patients delivered by cesarean section will be randomized to NSAIDS Vs NSAIDS plus opioid
- Trial name
- IVY (NCT03372382)
- Testing
- Ibuprofen, Acetaminophen, Norco
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Microbiota, Postoperative Recovery
The Effect of Oral Gan Shuangbi During the Perinatal Period on the Recovery of Intestinal Function After Cesarean Section in Pregnant Women- A Multicenter, Double-blind, Randomized Controlled Clinical Trial
This study aims to evaluate the effect of probiotics 7 days before cesarean section (CS) on postoperative recovery and the change of gut microbiota in pregnant women.
- Trial name
- NCT06347770
- Testing
- Probiotic Blend Oral Tablet
- Where
- 2 sites in China
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Zhe Li
Hypothermia; Anesthesia
Evaluation of the Active Warming Effects on Maternal and Neonatal Outcome During Cesarean Delivery
A prospective randomized study of healthy term parturients undergoing cesarean delivery was designed to assess the impact of the active warming on perioperative and postoperative temperature.
- Trial name
- NCT03473470
- Testing
- forced air warming and warmed intravenous fluids, warmed intravenous fluids
- Where
- Italy
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Cesarean Wound Disruption With Postnatal Complication
Impact of Preoperative Bathing on Post Caesarean Section Surgical Site Infection
Surgical site infection (SSI) is the commonest hospital-acquired infection globally, and prevalence is much higher in the low-income countries. Caesarean delivery carries a 5-20 fold risk for developing postpartum sepsis.
- Trial name
- SSI-MUST (NCT03544710)
- Testing
- preoperative bathing with antiseptic
- Where
- Uganda
- Volunteers
- 96 people
- Sponsor
- Mbarara University of Science and Technology
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