Clinical trials: C-Section
Cesarean Section, Restless Leg Syndrome
Neuraxial Anesthesia and Restless Leg Syndromes in Cesarean
The restless leg syndromes is a common sensorimotor disorder of unknown cause affecting approximately 10% of the population. Different literature had different views on the association between neuraxial anesthesia and the…
- Trial name
- NARELESS (NCT00872248)
- Testing
- Spinal anesthesia, Epidural anesthesia
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Nanjing Medical University
Post Spinal Anesthesia Hypotension
Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial
Neuraxial blockade such as spinal anaesthesia can cause severe hypotension due to pharmacological sympathectomy resulting in potential deleterious consequences for the patient, Prevention of this spinal anaesthesia induced…
- Trial name
- NCT06213935
- Testing
- Norepinephrine, Midodrine
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Post Spinal Anesthesia Shivering
Clonidine Versus Granisetron for Shivering Prevension
Prevention of post spinal anesthesia shivering during cesarean section with its associated discomfort, distress, aggravation of pain, increased metabolic demands, and increased oxygen consumption
- Trial name
- NCT06031090
- Testing
- Clonidine Injection, Granisetron Injection, Normal Saline 10 mL Injection
- Where
- Egypt
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cesarean Section; Infection
Evaluation of Triclosan Coated Suture in Obstetrical Surgery
A prospective comparative randomized blinded study conducted in the obstetrics gynecology department of Ben Arous hospital over an eight-month period between November 2020 and June 2021.
- Trial name
- NCT05330650
- Testing
- Coated Vicryl+, Vicryl
- Where
- Tunisia
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Tunis University
Antenatal Corticosteroids
Effect of Antenatal Corticosteroids on Neonatal Hypoglycemia
Comparing the incidence of neonatal hypoglycemia in infants born to mothers who received antenatal corticosteroids to those who did not.
- Trial name
- NCT06716918
- Testing
- Corticosteroid Injection
- Where
- Egypt
- Volunteers
- 188 people
- Sponsor
- Assiut University
Intracranial Pressure
Evaluation of the Effect on Optic Nerve Sheath Diameter in Patients Undergoing Cesarean Section
Depending on the physiology of pregnancy, the risk of increased aspiration, difficult airway, increased oxygen consumption and reduced functional residual capacity, breathing problems make general anesthesia application risky.
- Trial name
- EONSDCS (NCT03853889)
- Testing
- USG guided ONSD measurement preepidural
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Pain, Postoperative, Postoperative Nausea and Vomiting
Local Infiltration Analgesia With Ropivacaine Versus Placebo in Caesarean Section
The purpose of this study is to compare systematic local infiltration with Ropivacaine 0.5 % versus Ropivacaine 0.2 % versus Placebo in patients undergoing elective caesarean section.
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Cesarean Section
- Trial name
- NCT00891540
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Hvidovre University Hospital
Cesarean Section Wound
Interrupted Versus Continuous Subcuticular Skin Suturing in Elective Cesarean Section.
Non-diabetic pregnant women who undergo elective CS will be randomized into two groups: group I included women who has their skin closed with subcuticular interrupted mattress suture using non-absorbable polypropylene, and group…
- Trial name
- NCT03120806
- Testing
- Interrupted subcuticular skin closure, continuous subcuticular skin closure
- Where
- Egypt
- Volunteers
- 169 people
- Sponsor
- Cairo University
Anesthesia, Obstetrical
The Comparison Of Nerve Blocks In Cesarean Delivery
The purpose of this study is to investigate the effect of different kinds of popular peripheral nerve blocks for postoperative analgesia after cesarean delivery is completed, compared with traditional epidual analgesia.
- Trial name
- NCT03333902
- Testing
- QLB, Intravenous patient controlled analgesia (PCA)
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Feng Xia
Postoperative Pain After Cesarean Section
Interferential Current and Transcutaneous Electrical Nerve Stimulation for Pain After Cesarean Section
This study aims to compare the immediate and short-term effects of interferential current therapy and conventional transcutaneous electrical nerve stimulation (TENS) with placebo stimulation on pain and postpartum comfort…
- Trial name
- IC-TENS-CS (NCT07847502)
- Testing
- Conventional TENS, Interferential Current Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Dilara Özen Oruk
Chronic Pain, Cesarean Section Complications
Reducing Chronic Pain Following Cesarean Delivery
This pilot study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain relief skills class, to postpartum women with ongoing pain and/or pain interference following cesarean…
- Conditions
- Chronic Pain, Cesarean Section Complications, Postpartum
- Trial name
- NCT07799883
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Post-operative Pain
Intraoperative TAP Block After Repeat Cesarean
The aim of this study is to perform a randomized trial to investigate if intraoperative surgeon administered TAP block reduces pain and use of oral and parenteral pain medications after repeat cesarean delivery.
- Trial name
- NCT05393908
- Testing
- TAP Block Group
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Surgery, Opioid Use
Opioid Prescribing After Cesarean Delivery
The number of opioid overdose deaths in the United States has quadrupled in 15 years, a dramatic manifestation of the current opioid abuse epidemic.
- Trial name
- NCT03168425
- Testing
- Tailored prescription, Control
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cesarean Delivery Affecting Newborn, Cesarean Delivery Affecting Fetus
Continuous Non-invasive Blood Pressure Measurement in C-section
The caesarean section is a frequently performed procedure in obstetrics and accounts for about 30% of all births in Germany. 55% to 68% of all caesarean sections are performed under spinal anesthesia.
- Conditions
- Cesarean Delivery Affecting Newborn, Cesarean Delivery Affecting Fetus, Cesarean Section Complications
- Trial name
- ClearBirth (NCT03402685)
- Testing
- ClearSight
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Charite University, Berlin, Germany
Hypotension
ET 50 for Post Caesarean Section Spinal Hypotension
Hypotension is extremely common after induction of spinal anesthesia for cesarean delivery. Anesthetic blockade of the sympathetic outflow of the spinal cord causes vasodilation, and is one cause of this hypotension.
- Trial name
- ET-50 (NCT01561274)
- Testing
- 2 ml bupivacaine, 1.5 ml bupivicaine.
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cesarean Delivery
Does Warming Mothers During Cesarean Delivery Help Keep Babies Warm When Delivered?
The purpose of this study to investigate whether using a special warming blanket during Cesarean delivery helps maintain a normal body temperature in the baby when compared to mothers that are not warmed (standard care at BC…
- Trial name
- NCT00616174
- Testing
- Active warming with Bair Hugger blanket
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Isthmocele, Cesarean Scar Defect
Clinical Impact of Uterine Repair During Cesarean Section With Barbed Suture on the Incidence of Isthmocele
Pregnant women, irrespective of their pregnancy risk, who undergo a cesarean section for any reason will be randomized to one of two suturing techniques: conventional suture or barbed suture for uterine repair after the cesarean…
- Conditions
- Isthmocele, Cesarean Scar Defect, Pelvic Pain, Spotting
- Trial name
- CESARIS (NCT06691750)
- Testing
- Barbed suture, Conventional smooth suture
- Where
- Spain
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Post-spinal Hypotension, Cesarean Section
Epinephrine Infusion for Prophylaxis Against Maternal Hypotension During Caesarean Section
Maternal hypotension after spinal block is a common complication after subarachnoid block in this population. The incidence of maternal hypotension is nearly 60% when prophylactic vasopressors are not used.
- Trial name
- NCT05051150
- Testing
- Epinephrin 0.03, Epinephrin 0.05, Epinephrin 0.07
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Kasr El Aini Hospital
Venous Thromboembolism, Postpartum Period
Pilot PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity
The pilot PARTUM trial is a randomized, multicenter, placebo-controlled trial. Women who are at modest risk of VTE (as defined by the inclusion criteria) will be identified during pregnancy, labor and delivery and up to 48 hours…
- Conditions
- Venous Thromboembolism, Postpartum Period, Aspirin
- Trial name
- PARTUM (NCT04153760)
- Testing
- Aspirin 81 mg
- Where
- 7 sites in Canada, France and 2 more
- Volunteers
- 257 people
- Sponsor
- University of Calgary
Breastfeeding
The Effect of Mindfulness-Based Breastfeeding Programme in Mothers After Cesarean Delivery
The study is a randomised controlled trial designed to determine the effect of the Mindfulness-Based Breastfeeding Programme on maternal breastfeeding awareness, breastfeeding attitudes and breastfeeding continuation among…
- Trial name
- NCT06252311
- Testing
- Mindfulness-Based Breastfeeding Programme
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
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