Clinical trials: C.Surgical Procedure
Heart; Dysfunction Postoperative, Cardiac Surgery, C.Surgical Procedure; Cardiac
Goal Directed Therapy Aiming to Optimise Oxygen Central Venous Saturation in Children Undergoing Cardiac Surgery
The purpose of this study is evaluate goal-directed therapy with continuous central venous saturation compared to standard therapy in children undergoing cardiac surgery.
- Trial name
- NCT03469440
- Testing
- Continuous central venous oxygenation monitoring, Standard protocol
- Where
- Brazil
- Volunteers
- 65 people
- Sponsor
- Instituto do Coracao
C.Surgical Procedure; Cardiac, Blood Transfusion
Cost-Utility Analysis of Management of Peri Operative Haemorrhage Following Cardiac Surgery With Cardiopulmonary Bypass
Peri operative haemorrhage following cardio Pulmonary Bypass may occur in 5 to 10% of cardiac surgical interventions. Treatment of such complication often necessitates various combinations therapeutic intervention including…
- Conditions
- C.Surgical Procedure; Cardiac, Blood Transfusion, Blood Coagulation Disorders, Bypass, Cardiopulmonary
- Trial name
- IMOTEC (NCT02972684)
- Testing
- Thrombo-elastometry POC testing
- Where
- 15 sites in France
- Volunteers
- 1,098 people
- Sponsor
- Nantes University Hospital
Perioperative/Postoperative Complications, C.Surgical Procedure; Digestive System
Non-invasive Early Goal Directed Therapy in Colorectal Surgery: a Feasibility Study
The Nexfin monitoring system offers a complete non-invasive approach to a continuously estimation of blood pressure, CI and PPV by means of finger-cuff based pulse contour analysis.
- Trial name
- NCT02559141
- Testing
- Dobutamine
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Schleswig-Holstein
C.Surgical Procedure; Vascular (Peripheral)
Seal-V Safety and Performance Study
The purpose of this study is to further assess the safety and performance of Seal-V as an adjunct to standard surgical procedure for achieving hemostasis in patients undergoing peripheral vascular reconstruction surgeries using…
- Trial name
- NCT01625481
- Testing
- Seal-V
- Where
- 3 sites in Israel
- Volunteers
- 23 people
- Sponsor
- Sealantis Ltd.
C.Surgical Procedure
Assessement of the C-ARM ARCO FP-Rk521 S in Surgical Conventional Practice
THALES-EVAQUAL study assesses the quality of the images generated by C-ARM ARCO FP-Rk521S and its ability to be used during surgery.
- Trial name
- NCT03241290
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Grenoble
C.Surgical Procedure; Cardiac, Cardiac Dysrhythmia
Bridge Occlusion Balloon in Lead Extraction Procedure
To evaluate the use of an occlusion balloon (Bridge™ Occlusion Balloon, Spectranetics) within the Superior Vena Cava in lead extraction patients.
- Conditions
- C.Surgical Procedure; Cardiac, Cardiac Dysrhythmia, Disorder of Pacing Function
- Trial name
- NCT02714153
- Testing
- Bridge Balloon
- Where
- 7 sites in United States
- Volunteers
- 23 people
- Sponsor
- Yale University
C.Surgical Procedure, Stress
Music Therapy as an Adjunct in CIED Lead Extraction Procedures
The study will investigate possible effects of music therapy as an adjunct in an invasive cardiac procedure where infected or broken pacemaker leads, or leads from implantable cardioverter-defibrillators are removed from inside…
- Conditions
- C.Surgical Procedure, Stress, Pain, Procedural, Anxiety
- Trial name
- MATH (NCT04172662)
- Testing
- Facilitated Music Listening
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- Oslo University Hospital
C.Surgical Procedure; Cardiac
A Case Control Study to Identify the Role of Epigenetic Regulation of Genes Responsible for Energy Metabolism and Mitochondrial Function in the Obesity Paradox in Cardiac Surgery
This is a prospective, single-centre case control comparison of expression of target genes responsible for energy utilisation, mitochondrial function and oxidative stress and levels of histone acetylation/ DNA methylation in…
- Trial name
- Ob-Card (NCT02908009)
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Leicester
C.Surgical Procedure; Cardiac
Effects on Organ Damage and Surgical Outcome of a New Cardiopulmonary Pass System (EVADO)
The primary purpose of this study is to assess the effects of the use of EVADO with respect to a conventional cardio-pulmonary bypass (CBP) system on surgical morbidity and mortality.
- Trial name
- EVADO (NCT01805466)
- Testing
- EVADO, Conventional CPB
- Where
- 4 sites in Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS San Raffaele Roma
C.Surgical Procedure; Cardiac
HELIox CardiOPlegia Trial During Cardiac surgERy
The HELICOPTER-1 Trial is a single centre pilot study to determine the feasibility of administering Heliox in cardioplegia during cardiac surgery and whether it has the potential to reduce the incidence and severity of myocardial…
- Trial name
- HELICOPTER-1 (NCT02745951)
- Testing
- Heliox, Standard of care
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Unity Health Toronto
C.Surgical Procedure; Cardiac
Prospective Trial of Autologous Platelet Rich Plasma in Aortic Surgery
The purpose of this study is to determine whether autologous platelet rich plasma (APRP)is effective in reducing allogeneic blood transfusions during aortic surgery using deep hypothermic circulatory arrest.
- Trial name
- NCT02513862
- Testing
- Autologous Platelet-Rich Plasma Harvest Technique
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Hongwen Ji
Anesthesia, Airway Device
Laryngeal Mask in Upper Gastrointestinal Procedures
Diagnostic and operative procedures of upper gastrointestinal (GI) tract are very common in all patients. Some procedures are difficult to tolerate because of long duration, prone position or significant stimulation of the upper…
- Conditions
- Anesthesia, Airway Device, C.Surgical Procedure; Gastrointestinal
- Trial name
- SeoMask (NCT03567928)
- Testing
- Sedation with Gastro Cuff Pilot Laryngeal Mask, Propofol
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Ospedale San Raffaele
C.Surgical Procedure; Cardiac
Acute Normovolemic Hemodilution in High Risk Cardiac Surgery Patients.
Transfusions are one of the most overused treatments in modern medicine, and saving blood is one important issue all around the world.
- Trial name
- ANH (NCT03913481)
- Testing
- Acute normovolemic hemodilution, Standard care
- Where
- 32 sites in United States, Bahrain and 9 more
- Volunteers
- 2,000 people
- Sponsor
- Università Vita-Salute San Raffaele
C.Surgical Procedure; Cardiac, Acute Kidney Injury
Portal Flow Pulsatility as a Risk Factor for Acute Kidney Injury After Cardiac Surgery
The purpose of this study is to evaluate the possible association between portal vein flow pulsatility and acute kidney injury after cardiac surgery.
- Conditions
- C.Surgical Procedure; Cardiac, Acute Kidney Injury, Postoperative Complications, Right-Sided Heart Failure
- Trial name
- PP-AKI (NCT02831907)
- Testing
- Cardiac surgery
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- Montreal Heart Institute
C.Surgical Procedure; Cardiac, Blood Coagulation Disorders
Fibrinogen Concentrate In Children Cardiac Surgery 2
The purporse of this study is evaluate whether fibrinogen concentrate reduces postoperative bleeding in pediatric cardiac surgery with cardiopulmonary by-pass.
- Conditions
- C.Surgical Procedure; Cardiac, Blood Coagulation Disorders, Hypofibrinogenemia
- Trial name
- FiCCS2 (NCT03884725)
- Testing
- Fibrinogen Concentrate, control
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Filomena R B G Galas