Clinical trials: CABG
Cardiovascular Diseases, Coronary Disease
Effects of Personality and Context on Recovery From Coronary Artery Bypass
To study the personality and environmental factors that may determine the short-term and long-term sequelae of coronary artery bypass surgery (CABS).
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Depression
- Trial name
- NCT00005334
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Bypass Surgery, Cognitive Impairment
Evaluation of the Safety and Efficacy of Ang-(1-7) to Enhance Cognitive Function in Participants Undergoing CABG
Coronary Artery Bypass Graft (CABG) is a surgical procedure known to be associated with cognitive impairment. Mechanisms of cognitive impairment are complex but may include insufficient oxygenation and inflammation due to…
- Trial name
- NCT03252093
- Testing
- Angiotensin-(1-7)
- Where
- 5 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Arizona
Coronary Artery Bypass, Thrombosis
Evaluating the Role of Thrombin in Saphenous Vein Graft Failure After Heart Bypass Surgery
Heart bypass surgery, also known as coronary artery bypass graft (CABG) surgery, creates a detour around the blocked part of a heart artery to restore blood supply to the heart muscle.
- Trial name
- NCT00481806
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Arizona
Anxiety, Postoperative Pain
The Effect of Video-assisted Mobilisation Training on Mobility, Anxiety and Pain After Coronary Artery Bypass Surgery
This study is a Randomized Controlled trial.The aim of this study was to investigate the effect of preoperative routine patient education and video-assisted mobilization training on postoperative mobility, anxiety level and pain…
- Trial name
- NCT06117033
- Testing
- video assisted mobilization training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Namik Kemal University
Coronary Artery Disease
Bypass Surgery Versus Everolimus-Eluting Stent Implantation for Multivessel Coronary Artery Disease (BEST)
The purpose of this study is to determine whether the safety and efficacy of coronary stent implantation using Everolimus-Eluting Coronary Stent System (Abbott, Boston Scientific) is not inferior to coronary artery bypass…
- Trial name
- BEST (NCT00997828)
- Testing
- everolimus-eluting stent, coronary artery bypass graft surgery
- Where
- 27 sites in China, Malaysia and 2 more
- Volunteers
- 888 people
- Sponsor
- Seung-Jung Park
Atrial Fibrillation
Effect of Venous Cannulation on the Incidence of Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass
Context Atrial fibrillation is the most frequent arrhythmia following coronary artery bypass grafting. POAF is associated with worse outcomes following CABG.
- Trial name
- NCT04641611
- Testing
- Bicaval cannulation, Cavoatrial cannulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Jean-Francois Morin
Ischaemic Heart Disease, Prehabilitation
CABGpreHAB - a Feasibility Study Protocol
Patients with ischemic heart disease (IHD) awaiting coronary artery bypass graft (CABG) surgery often face challenges like advanced age, frailty, comorbidities, and physical inactivity.
- Conditions
- Ischaemic Heart Disease, Prehabilitation, Coronary Artery Bypass, Feasibility Studies
- Trial name
- NCT07035171
- Testing
- Multimodal prehabilitation intervention, Control (Standard treatment)
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Myocardial Ischemia, Coronary Artery Bypass Surgery
Humanin Isoforms in Cardiac Muscle and Blood Plasma and Major Complications After Cardiac Operation
Objective of the study is to clarify humanin-like peptide concentration in myocard tissue and in blood and to study if its concentration level is related to early complication occurrence and frequency after cardiac operation.
- Trial name
- NCT03431844
- Where
- 2 sites in Estonia
- Volunteers
- 106 people
- Sponsor
- University of Tartu
Coronary Artery Disease, Postoperative Complications
Intraoperative Targeted Versus Liberal Blood Pressure Management in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
The goal of this clinical trial is to learn whether two approaches to anesthesia and blood pressure management can improve care for adults having off-pump coronary artery bypass grafting (OPCAB).
- Trial name
- NCT07787364
- Testing
- Targeted Blood Pressure Management, Liberal Blood Pressure Management, Remimazolam
- Volunteers
- 416 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Bypass Graft, CABG
High-intensity Inspiratory Muscle Training as a Pre-cardiac Rehabilitation in Heart Disease
Background/aim: Endothelial function is closely associated with coronary artery health among individuals being treated for heart disease.
- Trial name
- NCT06127147
- Testing
- IMT
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- University of Illinois at Chicago
Unconscious State
The Effect of BIS Monitorization to Intraoperative Anesthetic Consumption During Coronary Artery Surgery
213 patients undergoing elective on-pump coronary artery bypass grafting (CABG) were enrolled into this prospective-clinical trial.After hundred and sixty three patients were excluded due to various reasons, 50 patients were…
- Trial name
- NCT02520947
- Testing
- BIS, Desflurane
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Microcirculation, Fluid Therapy
Effects of Fluid Therapy on Microcirculatory Reactivity
Through preoperative fluid therapy, to investigate whether it can alleviate the microcirculation dysfunction after induction of anesthesia, and reduce the incidence of perioperative fluid therapy-related complications, thereby…
- Trial name
- NCT04982016
- Testing
- crystal therapy, colloid therapy
- Volunteers
- 126 people
- Sponsor
- Beijing Anzhen Hospital
Fracational Flow Reserve, Coronary Artery Disease
Preoperative Use of Fractional Flow Reserve in CABG Use and Effectiveness of FFR-based CABG in Real-life Practice
The use of fractional flow reserve (FFR) to guide coronary artery bypass graft (CABG) is controversial and not ubiquitously adopted across the units.
- Conditions
- Fracational Flow Reserve, Coronary Artery Disease, Coronary Artery Bypass Surgery
- Trial name
- NCT04379947
- Testing
- Fractional Flow reserve
- Sponsor
- University of Glasgow
Coronary Artery Disease, Stroke
Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass
Surgical occlusion of the left atrial appendage (LAAO) is sometimes performed during the cardiac surgery to reduce long-term risk of stroke.A previous study found that LAAO may be associated with increased risk of postoperative…
- Conditions
- Coronary Artery Disease, Stroke, Atrial Fibrillation
- Trial name
- NCT04220047
- Testing
- Left Atrial Appendage Resection and Marshall Ligament Amputation
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease, Coronary Artery Bypass
Glycemic Control Using Mobile-based Intervention in Patients With Diabetes Undergoing Coronary Artery Bypass to Promote Self-management
The study is a two-arm parallel, randomized clinical trial. The purpose of the study is to evaluate the effectiveness and feasibility of using high-quality medication reminder smartphone application as a tool for secondary…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass, Diabetes Mellitus
- Trial name
- GUIDEME (NCT04192409)
- Testing
- Smartphone Application
- Where
- China
- Volunteers
- 1,038 people
- Sponsor
- China National Center for Cardiovascular Diseases
Paroxysmal Atrial Fibrillation, Coronary Artery Disease
The Assessment of Progression of Paroxysmal AF After CABG
The aim of this study is a comparative evaluation of progression of paroxysmal atrial fibrillation in patients with coronary artery disease after isolated CABG and CABG combined with pulmonary vein isolation.
- Trial name
- NCT02246803
- Testing
- CABG+Pulmonary vein isolation procedure, Isolated CABG
- Where
- Russia
- Volunteers
- 72 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Anemia, Iron Deficiency
Nutritional Optimization in Anemic Patients Scheduled for Elective Open-Heart Surgery
1. To test the effect and feasibility of culturally relevant SNP program in Anaemic patients scheduled for elective open-heart surgery versus those getting usual preoperative care in a public sector hospital. 2.
- Trial name
- Prehab_Nutri (NCT07801469)
- Testing
- Immune Modulating Formula, Whey Protein, Multivitamins and Iron Supplements
- Volunteers
- 140 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
D017202
ADR-002K for Patients With Ischemic Cardiomyopathy Who Undergo Coronary Artery Bypass Surgery
Ischemic cardiomyopathy undergoing coronary artery bypass surgery
- Trial name
- NCT04695522
- Testing
- ADR-002K administration
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Osaka University
Protective Effects of Acupuncture in Cardiac Surgery
Investigation of the Effectiveness of Electroacupuncture in Patients Undergoing Coronary Artery Bypass Surgery.
In China, acupuncture has been used for nearly 5,000 years to treat diseases and symptoms. Increasing evidence suggests that acupuncture, acupressure, and electroacupuncture (EA) may be useful in treating patients with…
- Trial name
- NCT06110780
- Testing
- acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Respiratory Rehabilitation
Pre-operative Respiratory Rehabilitation in Coronary Artery Bypass Graft Patients
To compare the effects of conventional preoperative respiratory rehabilitation and specific preoperative respiratory rehabilitation program on pulmonary functions in coronary artery bypass graft patients.
- Trial name
- NCT05736770
- Testing
- Respiratory rehabilitation and out of bed mobilization, conventional treatment
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Riphah International University