Clinical trials: CAD - Coronary Artery Disease
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Coronary Artery Ectasia
Endothelial Function in Patients With Ectatic Compared to Normal Coronary Arteries
The aim of this study is to show the frequency of endothelial dysfunction in patients suffering from ectatic coronary arteries as compared to those who have normal coronary arteries.
- Trial name
- NCT00548457
- Where
- Israel
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Coronary Artery Disease, Heart Failure
Harmonica Exercises for Patients Undergoing Cardiac Rehabilitation.
The study aims to assess the effects of exercises using the harmonica on the exercise capacity, the level of depressive symptoms and disease related quality of life in patients suffering from heart disease attending cardiac…
- Trial name
- HARMONYCR (NCT06647212)
- Testing
- introducing breathing exercises with the harmonica
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Katarzyna Piotrowicz
De Novo Stenosis, Coronary Artery Disease
Paclitaxel-Coated Balloon Versus Zotarolimus-Eluting Stent for Treatment of De Novo Coronary Artery Lesions
Coronary restenosis has been one of the main reasons affecting the prognosis of patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI).
- Conditions
- De Novo Stenosis, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- CAGE-FREEIII (NCT05209412)
- Testing
- Lepu Paclitaxel coated balloon, Resolute Integrity Zotarolimus eluting stents, Aspirin
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Xijing Hospital
Refractory Angina Pectoris, Ischemic Heart Disease
Cardiac Shock Wave Treatment in Patients With Reduced Coronary Flow Reserve
The purpose of the study is to assess the feasibility of Cardiac Shock Wave Treatment in patients with anginal chest pain and evidence of abnormal myocardial perfusion under stress in the absence of significant stenoses of the…
- Conditions
- Refractory Angina Pectoris, Ischemic Heart Disease, Coronary Artery Disease
- Trial name
- NCT03438500
- Testing
- Cardiac Extracorporeal Shockwave Therapy (Modulith SLC)
- Where
- Germany
- Sponsor
- Storz Medical AG
Coronary Heart Disease (CHD), PCI
Effects of Dioscorea Yam Gruel on Blood Lipid Profiles in PCI Patients With Coronary Heart Disease
This randomized controlled trial investigated the effects of Dioscorea yam gruel on blood lipid levels in patients with coronary heart disease after percutaneous coronary intervention (PCI).
- Trial name
- NCT07589036
- Testing
- Standard Post-PCI Care, Dioscorea Yam Gruel
- Where
- China
- Volunteers
- 72 people
- Sponsor
- 900th Hospital of PLA Joint Logistic Support Force
Coronary Artery Disease, Elderly (Aged >70)
Development and Validation of a cCTA and Biomarker Based Risk Model for Coronary Revascularization in Elderly Patients With Coronary Artery Disease
This study is a prospective multi-center observational cohort involving elderly patients (≥70 years old) with multi-vessel coronary disease identified by coronary computed tomography angiography (cCTA) and scheduled for invasive…
- Trial name
- NCT07311954
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 800 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Occlusive Disease
A Trial Comparing the Effect of Pravastatin and Rosuvastatin on Atherosclerosis Progression Measured by Carotid Intima Media Thickness in Patients With Coronary Artery Disease After Biolimus Eluting Stent (Nobori®) Implantation: CPR IMT
Current consensus papers recommend statin medication to reduce Low density lipoprotein (LDL) cholesterol level less than 100mg/dL (optional 70mg/dL) in patients with coronary artery disease.
- Trial name
- NCT01872845
- Testing
- Pravastatin 40mg, Rosuvastatin
- Where
- South Korea
- Volunteers
- 671 people
- Sponsor
- Yonsei University
Coronary Artery Disease
Post Marketing Clinical Trial to Demonstrate the Performance of the MedHub AutocathFFR Device.
Patients with suspected coronary artery disease who are scheduled to undergo a coronary angiography procedure will be enrolled in the study.
- Trial name
- NCT04724057
- Testing
- AutocathFFR
- Volunteers
- 488 people
- Sponsor
- Medhub Ltd.
Frailty, Coronary Artery Disease
Funcional Recovery After Minithoracotomy or Sternotomy for CABG in Frail Patients
Frailty is a major predictor of adverse outcomes following coronary artery bypass grafting (CABG), being associated with increased postoperative complications, prolonged hospitalization, delayed functional recovery, and reduced…
- Conditions
- Frailty, Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
- Trial name
- MINIFRAGILE (NCT07742475)
- Testing
- Minimally Invasive Coronary Artery Bypass Grafting (MICS-CABG), Conventional Coronary Artery Bypass Grafting (Median Sternotomy)
- Volunteers
- 194 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Disease
Comparison of Scoring Balloon and Conventional Balloon Predilation Before Drug Coated Balloon for de Novo Lesion in Patients With High Bleeding Risk
This study is designed to investigate whether scoring balloon (non-slip element, NSE) predilation compared to non-compliant (NC) balloon predilation for de novo lesion in patients with high bleeding risk and planning to receive…
- Trial name
- PREPARE-NSE (NCT03817801)
- Testing
- NSE balloon, NC balloon
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Coronary Artery Disease
ESCALATion of Medical Therapy Following Multimodality Plaque Evaluation in High-risk Chronic Coronary Syndromes
ESCALATE will provide a thorough investigation of how anti-inflammatory therapy, with low-dose colchicine, affects patients with stable coronary artery disease.
- Trial name
- ESCALATE (NCT06469528)
- Testing
- Colchicine 0.5 MG
- Volunteers
- 50 people
- Sponsor
- King's College Hospital NHS Trust
Atherosclerosis, Cardiovascular Diseases
Multi-Ethnic Study of Atherosclerosis (MESA) - Ancillary Eye Study
To evaluate the relation of retinal microvascular characteristics to subclinical cardiovascular disease, clinical disease, and their risk factors in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease
- Trial name
- MESA-Eye (NCT00041444)
- Volunteers
- 6,176 people
- Sponsor
- University of Wisconsin, Madison
Coronary Artery Disease
Scoring-Balloon Angioplasty and Sirolimus-Eluting Balloon Angioplasty for the Treatment of Diffuse, Small Vessel Coronary Artery Disease (SCA-DEB Study)
This is a prospective, single-center, single-arm study to evaluate the feasibility and safety of the combination of Scoring-Balloon Angioplasty and Sirolimus-Eluting Balloon Angioplasty for the treatment of diffuse, small vessel…
- Trial name
- SCA-DEB (NCT06197022)
- Testing
- Mozec™ SEB Sirolimus Eluting Rx PTCA Balloon Dilatation Catheter
- Where
- Bulgaria
- Volunteers
- 106 people
- Sponsor
- University National Heart Hospital
Coronary Artery Disease, CT
Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention
The CT-PLAN PCI trial will evaluate whether CCTA-guided PCI improves procedural efficiency compared with routine PCI (without pre-procedural CCTA-guidance for PCI planning) using procedural time as the primary endpoint.
- Trial name
- CT-PLAN-PCI (NCT07691502)
- Testing
- CT-guided PCI, Routine PCI
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Minneapolis Heart Institute Foundation
To Assess the Presence of Internal Pudendal Artery Disease in Patients With Erectile Dysfunction Undergoing Coronary Angiography
Prevalence Of Internal Pudendal Artery Disease In Patients With Erectile Dysfunction Undergoing Diagnostic Coronary Angiography
Subjects in this study have recently had or are scheduled for a coronary angiography as part of their normal, routine medical care. This procedure uses x-ray imaging to see the inside of the heart's blood vessels.
- Trial name
- NCT01276145
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Chicago
Coronary Artery Disease
CYPHERTM Stent Post-Marketing Surveillance Registry (US-PMS)
The purpose of this PMS registry, named e-CYPHER Stent Registry, is to collect post marketing surveillance data on the CYPHERTM Sirolimus-eluting Coronary Stent following marketing approval, when used in normal clinical practice…
- Trial name
- NCT00245401
- Testing
- CYPHERTM Sirolimus-Eluting Coronary Stent
- Volunteers
- 2,070 people
- Sponsor
- Cordis US Corp.
Cardiovascular Diseases, Coronary Artery Disease
Senescence in Myocardial Infarction
The investigators of this study have found that after a heart attack, some heart cells rapidly age (become senescent) and release proteins that make the heart disease worse.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Aging, Atherosclerosis
- Trial name
- SMI (NCT07693712)
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Acute STEMI, PPCI
On vs Off-hour PPCI in STEMI Patients
ST-elevation myocardial infarction (STEMI) remains a leading cause of morbidity and mortality globally, and timely reperfusion with primary percutaneous coronary intervention (PPCI) is the gold-standard treatment1.
- Conditions
- Acute STEMI, PPCI, Observational Study, Coronary Artery Disease (CAD)
- Trial name
- On vs Off PPCI (NCT07860086)
- Where
- Egypt
- Volunteers
- 450 people
- Sponsor
- Assiut University
Coronary Artery Disease, Diabetes Mellitus, Type 2
PIPAF Platelets in the Pathogenesis of Ageing Associated Frailty
This is a prospective observational study aimed at testing the existence of an association between frailty, inflammatory status, and degree of platelet activation and reactivity in elderly subjects with type 2 diabetes or…
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Type 2, Alzheimer Disease
- Trial name
- PIPAF (NCT05798637)
- Testing
- Standard of care
- Where
- 2 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Perugia
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