Clinical trials: CBD, open to volunteers
Advanced Malignant Solid Tumor
Cannabis extrAct in Oncology Patients for the Treatment of TUmor Related Symptom Burden
CAPTURE is a prospective, interventional, randomized, phase 2, double-blind, placebo-controlled study assessing the therapeutic add-on effect of the balanced THC/CBD extract (Cannabis extract Avextra 10/10 oral solution) on…
- Trial name
- CAPTURE (NCT07459920)
- Testing
- Cannabis Extract Oil
- Where
- Italy
- Volunteers
- 156 people
- Sponsor
- National Cancer Institute, Naples
Alcohol Use Disorder (AUD), Withdrawal From Addictive Substance; Detoxification
Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving
Cannabidiol (CBD), one of the most prevalent cannabinoids in cannabis (marijuana) has been shown to reduce alcohol withdrawal symptoms in laboratory animals.
- Conditions
- Alcohol Use Disorder (AUD), Withdrawal From Addictive Substance; Detoxification, Craving
- Trial name
- NCT07148843
- Testing
- Cannabidiol (CBD)
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Johns Hopkins University
Sickle Cell Disease
Cannabidiol in Sickle Cell Disease
Randomized, placebo-controlled, double masked, dose finding study of twice daily cannabidiol given at 3 dose levels, 200mg, 400mg, and 600mg, compared to placebo for 4 weeks.
- Trial name
- SPICE (NCT06930703)
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
HIV, Cannabis
Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV
This study has the potential to contribute to a more complete understanding of the independent and combined effects of cannabis use and HIV on the brain and on inflammation.
- Conditions
- HIV, Cannabis, THC, Neuroinflammatory Disease
- Trial name
- CAMI (NCT05514899)
- Testing
- THC, CBD
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Cancer Stage I, Breast Cancer Stage II
Study Assessing the Efficacy and Safety of cANnabidiol Oral Solution for Joint Pain of Adjuvant enDOcrine theRApy in Patients With Early Breast Cancer
Phase III, single-center, randomized, double-blind, placebo-controlled, 2x2 cross- over study, assessing the efficacy of CBD in patients with early HR+ BC, presenting aromatase inhibitor-related musculoskeletal pain
- Conditions
- Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III, HR+ Breast Cancer
- Trial name
- PANDORA (NCT06787118)
- Testing
- CBD oil
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Chronic Pruritus, Eczema
Efficacy of Topical Cannabidiol for Eczema
Itching is a common symptom encountered in general medical practice. It can cause significant discomfort, disrupt sleep, and impair patients' quality of life.
- Conditions
- Chronic Pruritus, Eczema, Nummular Eczema, Atopic Dermatitis
- Trial name
- NCT06994520
- Testing
- Cannabidiol (CBD), Triamcinolone (TAC) 0.1% cream
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Khon Kaen University
Plantar Fasciitis
A Double-Blinded Study on Rapid and Sustained Pain Relief Topical Cannabidiol for Plantar Fasciitis
This prospective, double-blinded, placebo-controlled study evaluates the efficacy of a 6000 mg transdermal CBD cream in adults with plantar fasciitis. Fifty participants will apply either CBD or placebo once daily for one month.
- Trial name
- NCT07776405
- Testing
- transdermal CBD cream (Tolcylen®, Marlinz Pharma)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Osteoarthritis, Knee
CBD for Knee Osteoarthritis
Osteoarthritis is a disease that affects millions of Americans and is the leading cause of persistent pain and physical disability in the older adult population.
- Trial name
- SLACK-OA (NCT06414473)
- Testing
- Cannabidiol (CBD) Extract
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Hepatocellular Carcinoma, Cannabis
A Pilot Study on the Effect of Cannabis Oil in Untreatable Liver Cancer Patients
to study the anti-tumor effect of cannabis oil (THC10% / CBD5%) in untreatable HCC patients based on mRECIST and RECIST criteria
- Trial name
- CanHep (NCT06518434)
- Testing
- Medical Cannabis
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Migraine Disorders
Evaluation of Efficacy and Safety of Topical Cannabidiol (Canvert-M Produced by Alasht Pharmed co. Iran) in the Treatment of Migraine Attacks
Canvert-M (manufactured by Alasht Pharmed Co. Iran) is a topical roll-on formulation that contains cannabidiol, peppermint, lavender, rosemary, eucalyptus, wintergreen, basil oil, etc.
- Trial name
- NCT07093138
- Testing
- Canvert-M (Produced by Alasht Pharmed co. Iran)
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Alasht Pharmed
Cannabis Use Disorder
Cannabidiol and Cannabis Concentrate Users
This study is a randomized, placebo-controlled, dose-ranging trial of plant-derived cannabidiol (CBD) among people who regularly use cannabis concentrates but are not trying to stop or cut down on their use.
- Trial name
- NCT06575751
- Testing
- Broad Spectrum Cannabidiol (bsCBD) 400 mg, Broad Spectrum Cannabidiol (bsCBD) 200 mg
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Complex Regional Pain Syndrome
The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome
The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS).
- Trial name
- NCT06393101
- Testing
- BRC-002
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- University of California, San Diego
Cannabis, Abuse Liability
Repeated CBD Administration and Cannabis Outcomes
This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.
- Conditions
- Cannabis, Abuse Liability, Experimental Pain in Healthy Human Participants
- Trial name
- NCT07434895
- Testing
- Cannabidiol, Medium Dose, Cannabidiol, Higher Dose, Active Inhaled Cannabis
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hannah Harris
Endometriosis, Adenomyosis
Assessing the Mechanisms and Impact of a Novel Cannabinoid Product for Gynecologic Pain
Despite recent increases in both medical and recreational cannabis use in the United States and globally, little research has been conducted to determine the potential applications for womens health.
- Conditions
- Endometriosis, Adenomyosis, Chronic Pelvic Inflammatory Disease
- Trial name
- PAIN-GP (NCT07728695)
- Testing
- Custom-formulated, high-CBD study product
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Staci Gruber, Ph.D.
Healthy Aging, Cognition
Effects of Cannabidiol on Memory and Attention in Adults Aged 60-70: A Pilot Study
This pilot study aims to investigate the effects of a single oral dose of cannabidiol (CBD) on memory and attention in healthy adults aged 60 to 70 years.
- Trial name
- CBD-MAP (NCT07910292)
- Testing
- Cannabidiol (CBD)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Chronic Migraine
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain.
- Trial name
- CAN-CHA (NCT05337033)
- Testing
- MPL-001
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Mediciine, Systemic Sclerosis (SSc)
Topical Cannabidiol Lotion for Pruritus Relief in Scleroderma
Itching is one of the common symptoms found in patients with scleroderma, with a prevalence of about 42-62%, and it often occurs in the early stages of the disease.
- Conditions
- Mediciine, Systemic Sclerosis (SSc), Intervention Study
- Trial name
- cannabidiol (NCT07245238)
- Testing
- 10% urea lotion plus 1% cannabidiol, Control
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Khon Kaen University
Osteoarthitis
CBD Knee Osteoarthritis Study
Osteoarthritis of the knee is a common cause of pain in the US. The currently available medicines for knee osteoarthritis sometimes are not effective at relieving the pain or have unacceptable side effects.
- Trial name
- NCT07638189
- Testing
- Cannabidiol (CBD)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Tennessee
Alzheimer Disease
Cannabidiol Medication Intervention Trial
CALM-IT is a Randomized, double-blind, placebo-controlled cross-over clinical trial. Safety and efficacy of cannabidiol (CBD) capsules assessed for managing agitation in patients with AD and to identify novel biomarkers of…
- Trial name
- CALM-IT (NCT06014424)
- Testing
- CBD
- Where
- 5 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Sunnybrook Health Sciences Centre