Clinical trials: CD - Crohn's Disease
Crohn's Disease
Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease
The primary objective of this study is to observe the long-term safety of filgotinib in adults who have completed or met protocol specified efficacy discontinuation criteria in a prior filgotinib treatment study in Crohn's…
- Trial name
- DIVERSITY LTE (NCT02914600)
- Testing
- Filgotinib
- Where
- 486 sites in United States, Argentina and 38 more
- Volunteers
- 1,188 people
- Sponsor
- Lakefront Biotherapeutics NV
Inflammatory Bowel Diseases
Intestinal Mesenchymal Stem Stells and Inflammatory Bowel Diseases
The exact origin of inflammatory bowel disease (IBD) is still unknown. The current hypothesis is that IBD is secondary to an abnormal intestinal immun response directed to all or part of the intestinal flora in genetically…
- Trial name
- COSMIC (NCT03115749)
- Testing
- Intestinal biopsies during colonoscopy, Biopsies taken on surgical specimen
- Where
- France
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Crohn's Disease
Open Label Study to Evaluate Long Term Efficacy, Safety and Tolerability of Repeated Dosing in Subjects With Crohn's Disease and Who Participated and Successfully Completed M14-115
The purpose of this study is to evaluate the long term efficacy, safety, and tolerability of repeated administration of adalimumab in participants with Crohn's disease.
- Trial name
- NCT02185014
- Testing
- Adalimumab
- Volunteers
- 252 people
- Sponsor
- AbbVie
Crohn's Disease
Development of Workshop for Lifestyle Changing for Crohn's Disease Patients and Its Affect on the Disease's Indexes
Subjects that participate in the practical workshop will improve their quality of life and will stay longer in remmision , in compare to the participants that will continue their regular threatment
- Trial name
- NCT00376649
- Testing
- lifestyle changing workshop
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Crohn's Disease
CT-P13 (Infliximab) Subcutaneous Administration in Patients With Moderately to Severely Active Crohn's Disease (LIBERTY-CD)
This is Phase 3, Randomized, Placebo-controlled study to demonstrate superiority of CT-P13 SC over Placebo SC in Patients With Moderately to Severely Active Crohn's Disease
- Trial name
- NCT03945019
- Testing
- CT-P13 SC (Infliximab)
- Where
- 29 sites in United States, Belarus and 24 more
- Volunteers
- 396 people
- Sponsor
- Celltrion
Crohn's Disease
COMMIT (Combination Of Maintenance Methotrexate-Infliximab Trial)
The primary objective is to compare the efficacy and safety of infliximab plus methotrexate to infliximab alone for the long-term control of signs and symptoms of Crohn's disease (CD) in patients with symptoms that are persistent…
- Trial name
- NCT00132899
- Testing
- Methotrexate
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- University of Western Ontario, Canada
Crohn Disease
Active Surgical Intervention on Crohn's Disease
The study is to determine whether active surgical intervention promotes disease remission in patients with Crohn's Disease (CD).The management of CD involves both maintenance medication and medication used to control flares of…
- Trial name
- NCT05523050
- Testing
- active surgical intervention
- Volunteers
- 100 people
- Sponsor
- Wuxi People's Hospital
Crohn's Disease, Ulcerative Colitis
The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation, Endothelial Function, and Markers of Inflammation
Fifty patients will get probiotics (109 bacteria [L. acidophilus, B. bifidum, S. thermophilus, L. rhamnosus, L. casei] in 2 capsules) and half will get placebo (2 capsules that look the same like the probiotic capsules and will…
- Trial name
- NCT01078935
- Testing
- probiotics
- Volunteers
- 100 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Crohn's Disease
Specific Carbohydrate Diet as Maintenance Therapy in Crohn's Disease
This study investigates whether the specific carbohydrate diet (SCD) can maintain clinical remission in pediatric and adult patients with Crohn's disease.
- Trial name
- SCD (NCT01749813)
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Crohn's Disease
Evaluation of Capsule Endoscopy in Patients With Suspected Crohn's Disease
The aim of this study is to validate the ability of Capsule Endoscopy (CE) to accurately diagnose small bowel (SB) Crohns disease in patients with symptoms of abdominal pain and diarrhea.
- Trial name
- MA-51 (NCT00487396)
- Testing
- Capsule Endoscopy
- Where
- 11 sites in United States, Canada and 2 more
- Volunteers
- 98 people
- Sponsor
- Medtronic - MITG
Crohn Disease (CD)
Evaluation of Muscle Strength and Muscle Mass in Patients With Inflammatory Bowel Disease
This prospective observational study aims to evaluate the validity of ultrasonographic muscle measurements in patients with inflammatory bowel disease (IBD).
- Trial name
- IBDSARC (NCT07441447)
- Testing
- Muscle Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sakarya University
Spondyloarthropathy, Crohn Disease
The SpACE Study - Small Bowel Crohn's Disease and Spondyloarthropathies
Inflammatory bowel disease is clinically associated with spondylarthropathies in 5-15% of cases. Protocol colonoscopic assessment demonstrated asymptomatic inflammation characteristic of Crohn's disease in up to 1/3 of SpA…
- Trial name
- SpACE (NCT03064815)
- Testing
- Videocapsule endoscopy, colonoscopy, PROMETHEUS® IBD sgi Diagnostic™
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Crohn Disease
Discontinuation of Infliximab Therapy in Patients With Crohn's Disease During Sustained Complete Remission
The purpose of this study is to determine whether infliximab can favourably and safely be discontinued in patients with Crohn's disease in sustained complete clinical, biochemical, and endoscopic remission on infliximab.
- Trial name
- STOP IT (NCT01817426)
- Testing
- Infliximab
- Where
- 13 sites in Denmark, Finland and 2 more
- Volunteers
- 115 people
- Sponsor
- Copenhagen University Hospital at Herlev
Crohn's Disease
Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety Study of MT-1303 in Subjects With Crohn's Disease
The purpose of this study is to evaluate PK, PD and safety of a single oral dose of MT-1303 in subjects with Crohn's disease.
- Trial name
- NCT02148185
- Testing
- MT-1303
- Where
- 2 sites in Japan
- Volunteers
- 1 people
- Sponsor
- Tanabe Pharma Corporation
Inflammatory Bowel Disease, Crohn's Disease
Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease
Background: Inflammatory bowel disease (IBD) is a term used to describe disorders that cause long-term inflammation in the digestive tract. Symptoms include stomach pain, diarrhea, and bleeding.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT07619547
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Inflammatory Bowel Diseases, Crohn Disease
MOdel-Informed Precision Dosing of Ustekinumab and VEdolizumab in Inflammatory Bowel Disease
The goal of this clinical trial is to investigate if dosage of Ustekinumab (UST) and Vedolizumab (VDZ) based on Model-Informed Precision Dosing (MIPD) is equally as efficient in keeping adults with Inflammatory Bowel Disease…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- MOVE-IT (NCT06788340)
- Testing
- PK-model to decide when to dose Vedolizumab and Ustekinumab
- Where
- 6 sites in Denmark
- Volunteers
- 166 people
- Sponsor
- Odense University Hospital
Crohn Disease
Regulatory T-cells and Crohn's Disease
Aim: the main aim of this study is to investigate if immune cells (regulatory T-cells, Th17 cells and other immune cell types) or biomarkers can be used to predict the response or lack of response to treatment with Infliximab.
- Trial name
- CrohnReg (NCT02060318)
- Testing
- Infliximab
- Where
- Denmark
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Crohn's Disease
Autologous Hematopoietic Stem Cell Transplantation for Crohn's Disease Treatment
The purpose of this study is to evaluate the safety and potential clinical benefit of lymphoablation followed by autologous HSCT rescue in therapy refractory Crohn's disease
- Trial name
- HSCT (NCT01932658)
- Testing
- Hematopoietic stem cell transplantation
- Where
- United States
- Sponsor
- University of California, Los Angeles
Crohn's Disease
Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis
This study proposes a randomized prospective study comparing the Kono-S anastomosis to the standard side-to-side anastomosis.This will be a multi-center randomized prospective trial.
- Trial name
- NCT03256240
- Testing
- side-to-side functional end anastomosis, Kono-S analstomosis
- Where
- 15 sites in United States, Belgium and 4 more
- Volunteers
- 600 people
- Sponsor
- Weill Medical College of Cornell University
Crohn's Disease
A Study of Mirikizumab (LY3074828) in Participants With Active Crohn's Disease
The purpose of this study is to evaluate the safety and effectiveness of the study drug Mirikizumab in participants with active Crohn's Disease.
- Trial name
- SERENITY (NCT02891226)
- Testing
- Mirikizumab
- Where
- 108 sites in United States, Australia and 12 more
- Volunteers
- 191 people
- Sponsor
- Eli Lilly and Company
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.