Clinical trials: CES
Neurological Complication, in Particular TNS or CES
Observational Study on 2-chloroprocaine Hydrochloride 1%
The present study aims to evaluate the relationship between spinal block with 1% solution of 2-chloroprocaine hydrochloride and the onset of all possible neurological adverse events, with particular attention to Transient…
- Trial name
- PASS (NCT02067806)
- Testing
- 2-chloroprocaine hydrochloride, 1%
- Where
- Belgium
- Volunteers
- 394 people
- Sponsor
- Sintetica SA
Genital Psoriasis
A Study of Tildrakizumab in the Treatment of Genital Psoriasis (CZATCH-Genital-PsO)
The main aim of this study is to check the safety and effectiveness of tildrakizumab regarding the alleviation of symptoms in the genital area after administration according to the summary of product characteristics (SmPC) and to…
- Trial name
- NCT06029257
- Testing
- Tildrakizumab
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Almirall, S.A.
Rhinitis Allergic, Persistent
Evaluation of Safety of Levocetirizine in Routine Clinical Practice-non- Interventional Study
To evaluate over a period of 6 months the safety and the treatment satisfaction of newly prescribed levocetirizine in patients of age ≥ 2 years with persistent allergic rhinitis.
- Trial name
- NCT00598780
- Where
- United States
- Volunteers
- 7,870 people
- Sponsor
- UCB Pharma
Breast Cancer, Breast Diseases
Evaluation of TaiHao Breast Ultrasound Diagnosis Software RN-CES Descartes
A standard of truth "SOT" is determined based on the interpretation results of the case data by interpretation experts, and the SOT is compared with the detection results of this program's function for detecting suspected breast…
- Trial name
- NCT05792475
- Testing
- Define Standard of Truth (SOT) by Taihao Breast Cancer Diagnostic Software
- Where
- Taiwan
- Volunteers
- 3 people
- Sponsor
- TaiHao Medical Inc.
Depression
Neural Mechanisms With CES in Depression
This study will examine the effect of cranial electrotherapy stimulation (CES) treatment on adults with depression. Scalp based electroencephalogram (EEG) will be utilized to record the brain activity of participants whilst they…
- Trial name
- NCT04587531
- Testing
- Cranial Electrotherapy Stimulation
- Where
- United Kingdom
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Electromedical Products International, Inc.
Urinary Bladder, Overactive
A Study to Evaluate Quality of Life in Patients Switched to Solifenacin From Other Antimuscarinics
This is a 12 month non-interventional study with solifenacin succinate, evaluating the effect of solifenacin on quality of life (QoL) of patients previously treated with antimuscarinics (Males and Females with Overactive Bladder…
- Trial name
- VEST (NCT02087098)
- Testing
- Solifenacin
- Where
- 60 sites in Czechia
- Volunteers
- 2,000 people
- Sponsor
- Astellas Pharma Europe B.V.
Nocturia
A Study of Minirin Melt in Patients With Nocturia
This is a confirmation of safety profile for Minirin Melt in clinical practice.
- Trial name
- NCT01212224
- Where
- 81 sites in Czechia
- Volunteers
- 2,187 people
- Sponsor
- Ferring Pharmaceuticals
Obesity
A Study to Understand the Distribution of Obesity Classes and Obesity Related Diseases in People With Obesity Across Countries in Czech Republic, Hungary and Poland
The study is intended to understand the distribution of different obesity classes and obesity related diseases (diseases that present along with obesity) in patients with body mass index (BMI) ≥ 30 kg/m^2.
- Trial name
- ExplorEUEast (NCT05795166)
- Testing
- No treatment given
- Volunteers
- 1,241 people
- Sponsor
- Novo Nordisk A/S
Preterm Labor, Preterm Birth
Cervical Stiffness in Women With Threatened Preterm Labor
Women giving birth prematurely due to spontaneous preterm labor may exhibit signs and symptoms of preterm labor (PTL) which are mostly nonspecific.
- Trial name
- CZECH-TPTL (NCT07840235)
- Testing
- Pregnolia System
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Pregnolia AG
Major Depressive Disorder Co-Occurrent With Anxiety, Adult Patients
First choIce Antidepressants: General Practitioner's Treatment Approach in the Czech Republic
According to the local guidelines (Recommendation for General Practitioners), the first choice Anti-Depressant (AD) in Major Depressive Disorder (MDD) in primary care should be selective serotonin reuptake inhibitors (SSRI), e.g.
- Conditions
- Major Depressive Disorder Co-Occurrent With Anxiety, Adult Patients, Newly Diagnosed Depression
- Trial name
- FIAT (NCT05291897)
- Where
- 6 sites in Czechia
- Volunteers
- 28 people
- Sponsor
- Angelini Pharma Česká republika s.r.o.
Major Depressive Disorder
Efficacy of Cranial Electrotherapy Stimulation (CES) for the Treatment of Major Depressive Disorder
Efficacy of Cranial Electrotherapy Stimulation (CES) for the treatment of Major Depressive Disorder
- Trial name
- NCT03222752
- Testing
- Cranial Electrotherapy Stimulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Electromedical Products International, Inc.
Hepatitis B, Hepatitis A
Evaluation of Antibody Persistence & Immune Memory in Subjects Vaccinated During Adolescence With Twinrix™
This study will evaluate the immune response against Hepatitis-A (HAV) and Hepatitis B surface (HBs) antigen in healthy subjects aged 12 to 15 years (at the time of primary vaccination), who received vaccination course with GSK…
- Trial name
- NCT00875485
- Testing
- Blood sampling, Additional challenge dose
- Where
- 2 sites in Belgium, Czechia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Primary Immunodeficiency Diseases (PIDD)
Expanded Access to TAK-881 for People With Primary Immunodeficiency Diseases in the USA and Czech Republic
The expanded access program allows people to gain access to an unlicensed treatment on compassionate grounds. This study will provide access to TAK-881 for participants with PIDD who have completed study TAK-881-3002…
- Trial name
- NCT06955793
- Testing
- TAK-881, SC Investigational Needle Sets
- Sponsor
- Takeda
Asthma
Utilization of Fixed Combination (Budesonide/Formoterol and Salmeterol/Fluticasone and Beclomethasone/Formoterol) in Treatment of Asthma Patients
Moderate and severe asthma bronchiale is treated by fixed combination (budesonide/formoterol or salmeterol/fluticasone) in the Czech Republic.
- Trial name
- UFO (NCT01327001)
- Where
- 100 sites in Czechia
- Volunteers
- 2,815 people
- Sponsor
- AstraZeneca
Overactive Bladder
Efficacy and Safety Evaluating Study to Compare Uritos® (Imidafenacin) and Urotol® (Tolterodine) for Treatment of Overactive Bladder.
Objective of this study was confirmation on non-inferiority and validation of similar safety profile of new anti-muscarinic medicinal product Uritos® (Imidafenacin) in comparison with other product from m-cholinergic antagonists…
- Trial name
- NCT03575702
- Testing
- Uritos®, Urotol®
- Where
- 11 sites in Russia
- Volunteers
- 300 people
- Sponsor
- R-Pharm
Atopic Dermatitis
A Study to Evaluate the Quality of Life of Male and Female Adult Patients With Severe Refractory Atopic Dermatitis Treated With Dupilumab in Czech Republic
Assessment of the relationship between treatment response (EASI75) and change in quality of life (EQ-5D) by week 24. Description of the: Change in disease activity after 16 and 24 weeks Change in subject and family quality of…
- Trial name
- NCT05527964
- Where
- Czechia
- Volunteers
- 146 people
- Sponsor
- Sanofi
Dyslipidaemia
Statin Therapy Results in the Real World Practice in the Czech Republic
Statins are the first choice treatment of dyslipidemia, a major contributor to cardiovascular diseases. Statins also have enough evidence to demonstrate decrease of morbidity and mortality from cardiovascular diseases.
- Trial name
- STEP (NCT01055977)
- Where
- 95 sites in Czechia
- Volunteers
- 3,253 people
- Sponsor
- AstraZeneca
Hepatitis C, Chronic, Hepatitis C
Pharmacoeconomic Study Assessing the Cost of Chronic Hepatitis C Treatment With Peginterferon Alfa-2b (PegIntron) and Ribavirin (Rebetol) in the Czech Republic (Study P04588)(COMPLETED)
The objective of the study is to evaluate the costs associated with peginterferon alfa-2b (PegIntron) plus ribavirin (Rebetol) treatment for chronic hepatitis C in the Czech Republic.
- Trial name
- NCT00723632
- Testing
- peginterferon alfa-2b, ribavirin
- Volunteers
- 901 people
- Sponsor
- Merck Sharp & Dohme LLC
Osteoarthritis, Osteoarthritis, Knee
Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis
Osteoarthritis (OA) of the knee is the most frequent cause of knee pain after the age of 50 years. OA is a joint disease characterised by articular cartilage loss associated with structural changes in the cartilage and adjacent…
- Trial name
- DISSCO (NCT02688400)
- Testing
- Diacerein, Celecoxib
- Where
- 22 sites in Austria, Belgium and 3 more
- Volunteers
- 380 people
- Sponsor
- TRB Chemedica International SA
Anxiety
Clinical and Cost Effectiveness of Alpha-Stim AID CES
This is a single-centre research study in patients seen within an NHS Improving Access to Psychological Interventions (IAPT) service with suspected generalised anxiety disorder (GAD).
- Trial name
- NCT02901080
- Testing
- Alpha Stim AID cranial electrotherapy stimulation, Pregnancy test, Anxiety questionnaire
- Where
- United Kingdom
- Volunteers
- 161 people
- Sponsor
- Electromedical Products International, Inc.