Clinical trials: CES
Breast Cancer, Breast Diseases
Evaluation of TaiHao Breast Ultrasound Diagnosis Software RN-CES Descartes
A standard of truth "SOT" is determined based on the interpretation results of the case data by interpretation experts, and the SOT is compared with the detection results of this program's function for detecting suspected breast…
- Trial name
- NCT05792475
- Testing
- Define Standard of Truth (SOT) by Taihao Breast Cancer Diagnostic Software
- Where
- Taiwan
- Volunteers
- 3 people
- Sponsor
- TaiHao Medical Inc.
Chronic Pulmonary Thromboembolism
Early Detection of CTEPH in Patients After APE
The project is a national, prospective, multicenter, observational pilot project of screening CTEPH in pacients after APE in the Czech Republic.
- Trial name
- CTEPH (NCT06865326)
- Testing
- Standardized CTEPH Screening Protocol
- Where
- 10 sites in Czechia
- Volunteers
- 500 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Obstetric Anesthesia Care
Obstetric Anesthesia and Analgesia Month Attributes in Czech Republic
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia in Czech Republic.
- Trial name
- OBAAMA (NCT01830218)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 1,940 people
- Sponsor
- Charles University, Czech Republic
Smoking Cessation
UK-Czech E-cigarette Study
Currently available smoking cessation treatments help only about 15% of smokers to quit long-term. These treatments do not typically address the behaviours and sensations associated with the act of smoking (e.g.
- Trial name
- (SUKCES) (NCT01842828)
- Testing
- Standard care plus electronic cigarettes, Standard care
- Where
- United Kingdom
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Depression
Neural Mechanisms With CES in Depression
This study will examine the effect of cranial electrotherapy stimulation (CES) treatment on adults with depression. Scalp based electroencephalogram (EEG) will be utilized to record the brain activity of participants whilst they…
- Trial name
- NCT04587531
- Testing
- Cranial Electrotherapy Stimulation
- Where
- United Kingdom
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Electromedical Products International, Inc.
Fibromyalgia
Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia
The purpose of this study is to determine the effects of mild cranial electrical stimulation on pain, fatigue, sleep disturbances, perceived stress, blood pressure, and functional status in persons with fibromyalgia.
- Trial name
- NCT00928720
- Testing
- CES device
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Virginia
Postoperative Delirium (POD), Perioperative Neurocognitive Disorders
Ortopod CZ Pilot Study
ORTOPOD PILOT STUDY is a non-randomized, non-interventional clinical study that addresses the issue of perioperative neurocognitive disorder (deterioration of cognitive functions in the preoperative and perioperative period) and…
- Trial name
- ORTOPODCZ (NCT06869876)
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Tomas Bata Hospital, Czech Republic
Prostate Cancer, High Risk Prostate Cancer
Predictors of Nodal and Distant Metastatic Disease Detected by PSMA PET in Treatment-Naïve High-Risk Prostate Cancer: A Czech Multicentre Cohort Study
Prostate cancer is the second most common malignancy worldwide and the fifth leading cause of male cancer-related mortality. Approximately 15% of localized cases are classified as high-risk for biochemical recurrence.
- Conditions
- Prostate Cancer, High Risk Prostate Cancer, PSMA PET, Staging
- Trial name
- CZECH-PSMA (NCT07608419)
- Testing
- PSMA PET
- Volunteers
- 400 people
- Sponsor
- General University Hospital, Prague
Preeclampsia (PE), Fetal Growth Restriction
The Combined First Trimester Screening
The project is a national, prospective, multicenter pilot project. The project is focus on setting up the combined first trimester screening in the Czech Republic.
- Conditions
- Preeclampsia (PE), Fetal Growth Restriction, Congenital Abnormalities, Preterm Labor
- Trial name
- NCT07015203
- Where
- 3 sites in Czechia
- Volunteers
- 2,000 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Cauda Equina Syndrome
Brief ES for Recovery of Autonomic Function in CES
BESCES is a study that aims to explore the feasibility of intraoperative brief epidural electrical stimulation (ES) for patients undergoing routine decompression for cauda equina syndrome.
- Trial name
- BESCES (NCT06416878)
- Testing
- Brief ES at the time of decompression for cauda equina syndrome, Brief ES to facilitate mcturition/removal of catheter
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Liverpool
Urinary Bladder, Overactive
A Study to Evaluate Quality of Life in Patients Switched to Solifenacin From Other Antimuscarinics
This is a 12 month non-interventional study with solifenacin succinate, evaluating the effect of solifenacin on quality of life (QoL) of patients previously treated with antimuscarinics (Males and Females with Overactive Bladder…
- Trial name
- VEST (NCT02087098)
- Testing
- Solifenacin
- Where
- 60 sites in Czechia
- Volunteers
- 2,000 people
- Sponsor
- Astellas Pharma Europe B.V.
COVID-19, SARS-CoV-2
Molnupiravir and COVID-19 Mortality Reduction in the Omicron Era
This retrospective real-world target trial emulation uses complete Czech nationwide registry data to evaluate whether molnupiravir treatment is associated with lower COVID-19 mortality during the Omicron era.
- Trial name
- MOLCOVred (NCT07720596)
- Testing
- Molnupiravir
- Where
- Czechia
- Volunteers
- 1,795,570 people
- Sponsor
- Charles University, Czech Republic
Non-technical Skills
Observation of Non-technical Skills in the Pre-hospital Care in the Czech Republic
The aim of the study is to find out if the Emergency Medical Services (EMS) crews are using the non-technical skills (e.g. communication, decision making, situational awareness etc.) in the real practice and how well they use…
- Trial name
- NTS (NCT04503369)
- Testing
- Non-technical skills
- Where
- 3 sites in Czechia
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- David Peran
Anxiety, Depression
New Mothers Alpha-Stim
The birth of a child is a major life event that can be filled with excitement, anticipation and joy. However, the transition and adaptation to new demands, roles, responsibilities, and changes in relationships can be stressful…
- Conditions
- Anxiety, Depression, Insomnia, Sleep Quality
- Trial name
- NCT04770181
- Testing
- Alpha-Stim AID CES (Active Comparator)
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Christina Murphey, RN, PhD
Trauma, Brain
Risk Assessment of Mild Traumatic Brain Injury in Military Training
The SNIPER-TBI study aims to identify and quantify the risk of mild traumatic brain injury (mTBI) in soldiers of the Czech Armed Forces during specific high-risk training activities, including parachute jumps, high-caliber…
- Trial name
- NCT06992570
- Testing
- Quantification of mild trauma brain injury risk, Biomechanical Analysis of Head Impact Forces
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Autonomic Nervous System Imbalance
Effect of CES on Parasympathetic Tone
The hypothesis is that CES stimulation will dose dependently increase parasympathetic tone. Healthy subjects will have three 20 minute sessions of CES stimulation, at three different intensities of stimulation, with each session…
- Trial name
- NCT02163967
- Testing
- Cranial Electrical Stimulation Fisher-Wallace Stimulator (Model FW100)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Nocturia
A Study of Minirin Melt in Patients With Nocturia
This is a confirmation of safety profile for Minirin Melt in clinical practice.
- Trial name
- NCT01212224
- Where
- 81 sites in Czechia
- Volunteers
- 2,187 people
- Sponsor
- Ferring Pharmaceuticals
Covid19, Distress, Emotional
The Practice of Providing Palliative Care in the Situation of the COVID-19 (Coronavirus Disease 2019) Pandemic in Czech Republic
Pandemic of coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2) causing the disease COVID-19 (Coronavirus Disease 2019) overwhelmed healthcare and brought new challenges and stressful situations.
- Trial name
- PEOpLe-C19 (NCT04910243)
- Testing
- Questionnaire Survey
- Where
- Czechia
- Volunteers
- 307 people
- Sponsor
- Brno University Hospital
Chronic Kidney Diseases
Description of Treatment Patterns and Population Characteristics of Pre-dialysis CKD Patients in the Czech Republic
The decision making in the Czech nephrology offices depends on the local common practice which is likely to be heterogenous. In other words, the same patient would be indicated to different therapy and regimen at different sites.
- Trial name
- NCT05380843
- Where
- 5 sites in Czechia
- Volunteers
- 1,200 people
- Sponsor
- Value Outcomes Ltd.
Algorithm for Cervix Carcinoma Screening
Algorithm for Cervix Carcinoma Screening in CZ Using the Detection of HPV DNA and CINtec Plus
Cervix carcinoma has been a serious, long-term issue in the Czech Republic. The cause of nearly all cervix carcinomas is human papilomavirus (HPV).
- Trial name
- LIBUSE (NCT05578833)
- Testing
- HPV DNA test with selective HPV 16/18 genotyping (cobas® 4800 HPV Test, Roche), p16 and Ki-67 biomarker detection in the form of dual cytological staining (CINtec Plus, Roche), standard conventional cytology PAP test
- Where
- Czechia
- Volunteers
- 2,426 people
- Sponsor
- AeskuLab Pathology Prague