Clinical trials: CFS/ME
Cancer Related Fatigue, Fatigue Syndrome, Chronic
Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue (CFS/ME)
Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue Syndrome (CFS/ME) by Lipidomics, Metabolomics, Intestinal and Peritoneal Microbiome Analysis and Exome Analysis and Investigation of a Possible…
- Trial name
- IMPROFA (NCT03773003)
- Testing
- Probiotics
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Chronic Fatigue Syndrome
Use of a Monitor in ME/CFS
The use of an activity monitor to determine increase or decrease of activity in patients suffering from chronic fatigue syndrome.
- Trial name
- NCT01908036
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York CFS Association
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Effect of Probiotics in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a neurological disease. Currently there is no effective treatment for ME/CFS due to unclear etiology of the disease.
- Trial name
- NCT04741841
- Testing
- GutMagnific™ H., GutMagnific™ L.
- Where
- Sweden
- Volunteers
- 74 people
- Sponsor
- ImmuneBiotech Medical Sweden AB
ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis
ME/CFS Brain Fog: Cognitive Rehabilitation Trial
The purpose of this study is to compare two approaches to cognitive rehabilitation in adults with post-viral cognitive syndrome, which resulted in brain fog.
- Conditions
- ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19, Chronic Fatigue
- Trial name
- NCT07523113
- Testing
- Processing Speed Training, In-session Instrumental Activities of Daily Living Training, Transfer Package
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Chronic Fatigue Syndrome/ Myalgic Encephalitis (CFS/ME), Post COVID Syndrome
Effectiveness and Safety of a Tele-Rehabilitation Program on Fatigue and Related Variables in Chronic Fatigue Syndrome and Post COVID Syndrome
This is a randomized, single-blind clinical trial that aims to evaluate the effectiveness of a tele-rehabilitation program based on mindful and conscious movement-based exercise (including adapted yoga, breathing exercises, and…
- Trial name
- NCT06978582
- Testing
- Mindful and conscious movement-based exercise, Conventional exercise
- Where
- Spain
- Volunteers
- 147 people
- Sponsor
- University of Seville
Myalgic Encephalomyelitis, Long-COVID
Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions
The goal of this observational study is to assess the clinical response and the effect of autophagy function in patients before, during and throughout oral low dose sirolimus (rapamycin) therapy.
- Trial name
- NCT06257420
- Testing
- Rapamycin
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Simmaron Research Inc.
Chronic Fatigue Syndrome/ Myalgic Encephalitis (CFS/ME)
B-lymphocyte Depletion Using Rituximab in Chronic Fatigue Syndrome/ Myalgic Encephalopathy (CFS/ME). A Randomized Phase-III Study.
The hypothesis is that a subgroup of patients with Chronic Fatigue Syndrome/ Myalgic Encephalopathy (CFS/ME) have a chronically activated immune system and may benefit from B-lymphocyte treatment using the monoclonal anti-CD20…
- Trial name
- RituxME (NCT02229942)
- Testing
- Rituximab
- Where
- 5 sites in Norway
- Volunteers
- 151 people
- Sponsor
- Haukeland University Hospital
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Bright Light Therapy in ME/CFS Patients
In this study patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) will receive bright light therapy through portable lamps for 2 weeks.
- Trial name
- BLTME (NCT06635928)
- Testing
- Bright light therapy
- Where
- Austria
- Volunteers
- 36 people
- Sponsor
- Medical University of Vienna
Chronic Fatigue Syndrome in Adolescence, Postural Orthostatic Tachycardia Syndrome
POTS-CFS Study: Orthostatic Intolerance in the Context of Pediatric ME/CFS
Pilot-case-control study on exertion and orthostatic intolerance of adolescents with myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) compared to age-matched healthy controls (HC).
- Conditions
- Chronic Fatigue Syndrome in Adolescence, Postural Orthostatic Tachycardia Syndrome, Orthostatic Intolerance
- Trial name
- POTS-CFS (NCT06054958)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Post-COVID-19 Syndrome
Prednisolone and Vitamin B1/6/12 in Patients With Post-Covid-Syndrome
This is a multicenter, randomized, placebo controlled, double-blind phase III trial with four parallel groups studying studying the feasibility of RCT in primary care as well as the effectiveness of treatment with prednisolone…
- Trial name
- PreVitaCOV (NCT05638633)
- Testing
- Prednisolone 20 mg/ 5 mg, Vitamin B compound (100mg B1, 50 mg B6, 500 µg B12)
- Where
- 3 sites in Germany
- Volunteers
- 321 people
- Sponsor
- Wuerzburg University Hospital
Encephalomyelitis, Chronic Fatigue Syndrome
A Study Of Remote Voice Analysis Tool For Diagnosing And Monitoring ME/CFS
The purpose of this research is to evaluate the use of a voice-based tool in the diagnosis and management of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Trial name
- NCT07551999
- Testing
- Voice Recording
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Post-COVID / Long-COVID, ME/CFS
Vagus Nerve Stimulation to the Ear to Improve Symptoms in Post-COVID-19 and ME/CFS
This study is testing whether a gentle electrical stimulation of a nerve in the ear, called the vagus nerve, can help reduce fatigue and improve symptoms in people with Post-COVID Syndrome or Myalgic Encephalomyelitis/Chronic…
- Trial name
- STIMPACT (NCT06968104)
- Testing
- transcutaneous vagus nerve stimulation
- Where
- Luxembourg
- Volunteers
- 48 people
- Sponsor
- University of Luxembourg
Long COVID, Chronic Fatigue Syndrome
tVNS in Long COVID-19
A prior open label study has shown that transcutaneous vagus nerve stimulation [tVNS] can improve the health of some patients with postacute sequelae of SARS-CoV-2 infection (PASC), severely affected enough to also fulfill…
- Trial name
- NCT06585254
- Testing
- Transcutaneous vagus nerve stimulator
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Covid19, ME/CFS
Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry (INSPIRE)
The Innovative Support for Patients with SARS COV-2 Infections Registry (INSPIRE) study is a CDC-funded COVID-19 project to understand the long-term health outcomes in recently tested adults, both negative and positive, who have…
- Conditions
- Covid19, ME/CFS, SARS COV2, Novel Coronavirus Infection
- Trial name
- INSPIRE (NCT04610515)
- Where
- 8 sites in United States
- Volunteers
- 6,000 people
- Sponsor
- Rush University Medical Center
Chronic Fatigue Syndrome (CFS), Post-COVID ME/CFS
RCT of Efficacy and Safety of CP003 on CFS/ME or Post COVID-19 Fatigue
The goal of this clinical trial is to test if a Lingzhi supplement (CP003) helps people with chronic fatigue or post-COVID fatigue feel better. It will also check if the supplement is safe to use.
- Trial name
- NCT06739720
- Testing
- LingZhi capsule
- Where
- Hong Kong
- Volunteers
- 130 people
- Sponsor
- The University of Hong Kong
Chronic Fatigue Syndrome
Hydrogen Water Intervention With Heart Rate Variability as an Outcome Biomarker in ME/CFS
The goal of this clinical trial is to learn if the OTC supplement, hydrogen water, works to treat the fatigue-related symptoms and functional limitations in adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Trial name
- NCT07009691
- Testing
- Hydrogen water which is prepared from an OTC supplement.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stony Brook University
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
ME/CFS, Long COVID
Is Swimming a More Tolerable Form of Movement for Individuals With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome?
Individuals with ME/CFS experience profound exercise intolerance and post-exertional malaise. This remote (app-based) pilot study explores whether light, fully self-paced, swimming may be a tolerable form of movement for people…
- Conditions
- ME/CFS, Long COVID, Post- COVID-19 Syndrome, POTS - Postural Orthostatic Tachycardia Syndrome
- Trial name
- ME/CFS (NCT07454395)
- Testing
- Swimming, Cycling
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Chronic Fatigue Syndrome
The Feasibility, Acceptability and Clinical Utility of a New Remote-mobile Technology Intervention (ASARM) for CFS/ME in a Paediatric Population
This study aims to improve on the delivery of treatment for people with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). People with CFS/ME have low energy.
- Trial name
- ASARM (NCT02082730)
- Testing
- ASARM
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Chronic Fatigue Syndrome
Blood-Brain Barrier Integrity and Immune Dynamics in Neuropsychiatric Sequelae of Post-SARS-CoV-2 Onset ME/CFS Versus Pre-Pandemic ME/CFS Patients
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex chronic illness impacting multiple body systems and characterized by activity-limiting fatigue and post exertional symptom exacerbation, affecting over 3.5…
- Trial name
- MECFS BBB (NCT07256795)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University