Clinical trials: CHD
Pulmonary Hypertension
Study of Inhaled Iloprost in Pediatric Pulmonary Hypertension (PH) After Surgery
The aim of this study is to determine whether inhaled iloprost can be used to prevent and treat PH and PHC while in children after operation of CHD
- Trial name
- NCT01310751
- Testing
- iloprost nebuliser solusion, distilled water
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Angina Pectoris, Coronary Artery Disease
Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern
To investigate whether the use of Corus CAD (Age/Sex/Gene Expression score - ASGES) blood assay changes the diagnostic testing pattern in patients referred to a cardiologist for the evaluation of chest pain or anginal equivalent…
- Conditions
- Angina Pectoris, Coronary Artery Disease, Chest Pain, Cardiovascular Diseases
- Trial name
- IMPACT-CARD (NCT01251302)
- Testing
- Corus CAD (ASGES)
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- CardioDx
End Stage Renal Disease
Conventional Hemodialysis Vs Short Daily Hemodialysis for Patients Coming From Peritoneal Dialysis (HAPD/CAPD)
The purpose of this randomized study is to determine if the home SDHD is a suitable alternative to conventional dialysis performed in a dialysis center for patients suffering from chronic kidney disease from Peritoneal Dialysis…
- Trial name
- CHDvsSDHD (NCT02002949)
- Testing
- Short daily hemodialysis, Conventional hemodialysis
- Where
- 31 sites in Italy
- Volunteers
- 144 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Liver Injury, Hepatitis B Virus Infection History
Liver Injury by Statins in Patients With History of Hepatitis B Virus Infection
The purpose of this study is to investigate the incidence of liver injury by statins in coronary heart disease (CHD) patients with history of hepatitis B virus (HBV) infection.
- Trial name
- LISHBV (NCT02808299)
- Testing
- HBV infection history
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Hypercholesterolemia, Dyslipidemia
Follow-on Protocol of Pitavastatin Versus Simvastatin in Patients With Hypercholesterolemia or Dyslipidemia and Coronary Heart Disease Risk Factors
This is a sixteen-week follow-on and 28 week single-blind extension study for patients who participated in study NK-104-304.
- Conditions
- Hypercholesterolemia, Dyslipidemia, Coronary Heart Disease
- Trial name
- NCT00344175
- Testing
- pitavastatin, simvastatin
- Where
- 28 sites in Denmark, Netherlands and 2 more
- Volunteers
- 178 people
- Sponsor
- Kowa Research Europe
Augmented Reality, Nursing Education
Effect of Immersive Interactive Nursing Guidance on Anxiety, Cognition, and Self-efficacy in CHD Patients Undergoing Cardiac Catheterization
The purpose of this study is to explore the effect of immersive interactive nursing guidance on anxiety, disease cognition, self-efficacy and satisfaction in patients undergoing cardiac catheterization for coronary heart disease.
- Conditions
- Augmented Reality, Nursing Education, Anxiety, Immersive
- Trial name
- NCT07012200
- Testing
- Immersive Interactive Nursing Instruction, Routine Nursing Instructions
- Where
- Taiwan
- Volunteers
- 108 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Bone Diseases, Metabolic Syndrome X
Effect of Exercise and Phytoestrogen on Bone, Metabolic Syndrome Criteria and Complaints of the Early Menopause
The aim of the study is to compare the effect of a progressive, periodized exercise training designed to impact bone, CHD-risk-factors and menopausal complaints versus the combined effect of exercise and "phytoestrogen"…
- Conditions
- Bone Diseases, Metabolic Syndrome X, Coronary Disease
- Trial name
- NCT00663104
- Testing
- exercise, exercise + cimicifuga racemosa
- Where
- Germany
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Percutaneous Coronary Intervention, Coronary Heart Disease
Clinical Study of Endovascular Interventional Surgical Instrument Control System and Related Consumables in Percutaneous Coronary Intervention
The goal of this study is to evaluate the safety and effectiveness of endovascular interventional surgery instrument control system （ALLVAS®robot）and supporting consumables for coronary artery interventional surgery.
- Conditions
- Percutaneous Coronary Intervention, Coronary Heart Disease, Robotic Surgical Procedures
- Trial name
- NCT05642286
- Testing
- ALLVAS® robotic-assisted PCI
- Volunteers
- 218 people
- Sponsor
- Shanghai Operation Robot Co., Ltd.
Hypercholesterolaemia
PULSAR - A Prospective Study to Evaluate the Utility of Low Doses of the Statins Atorvastatin and Rosuvastatin.
To compare reduction of LDL-C and safety between 10mg rosuvastatin and 20mg atorvastatin after 6 weeks treatment
- Trial name
- NCT00329173
- Testing
- Rosuvastatin, Atorvastatin
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
Hypercholesterolemia
Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)
A 12 week clinical trial in patients 65 years of age and older with hypercholesterolemia at high risk for coronary heart disease to study the effects of atorvastatin and ezetimibe given in combination and two higher doses of…
- Trial name
- NCT00418834
- Testing
- ezetimibe and atorvastatin, atorvastatin
- Volunteers
- 1,053 people
- Sponsor
- Organon and Co
Coronary Heart Disease
Innovation Research of Differentiation and Treatment Methods Based on CHD Phlegm and Blood Stasis Syndrome
Coronary heart disease is still the major cause of death in China. Chinese medicine plays more and more important role in CHD prevention and treatment. Phlegm and blood stasis are its major pathological basis.
- Trial name
- NCT02967718
- Where
- China
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- Jingqing Hu
Pulmonary Hypertension
Multicenter Study of Iloprost Inhaled in Pulmonary Hypertension After Repair of Congenital Heart Diseases (CHD)
This study was designed to investigate treatment of postoperative pulmonary hypertension by iloprost inhalation in children with congenital heart defects.
- Trial name
- NCT01598441
- Testing
- iloprost nebuliser solution, distilled water
- Where
- 3 sites in China
- Volunteers
- 8 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Coronary Artery Disease
Influencing Factors and Outcomes of DCB Angioplasty
This ambiprospective observational study evaluates the long-term safety and efficacy of Paclitaxel Drug-Coated Balloon (DCB) angioplasty in approximately 20,000 patients withcoronary artery lesions in large vessels.
- Trial name
- FWHZ-DCB (NCT06620458)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Respiratory Syncytial Virus Infections
A Study to Assess Safety, Pharmacokinetics Anti-Drug Antibody and Anti-RSV Antibody After 2 Doses of Nirsevimab
The purpose of this study is to measure the safety, PK, occurrence of ADA to nirsevimab, and anti-RSV neutralizing Ab in Japanese children with certain health conditions or pre-term infants aged ≤12 months.
- Trial name
- JUBILUS (NCT06042049)
- Testing
- Nirsevimab
- Where
- 9 sites in Japan
- Volunteers
- 33 people
- Sponsor
- AstraZeneca
Congenital Heart Disease, Psychological Well-being
The Living Experience of Hong Kong Chinese Adolescents With CHD.
This study aims to explore the impacts of CHD and its limitations on adolescents and the living experience of adolescents living with CHD.
- Conditions
- Congenital Heart Disease, Psychological Well-being, Quality of Life, Adolescent
- Trial name
- NCT03677232
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
Coronary Heart Disease (CHD)
Continuous Comprehensive Nursing for Post-CABG Recovery
This study evaluates the effectiveness of a continuous comprehensive nursing (CCN) system compared to routine care for patients after coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT07062432
- Testing
- Continuous Comprehensive Nursing System, Routine Postoperative Care
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Hospital of Hebei Medical University
Cardiovascular Disease
Predictive Value of Coronary Heart Disease (CHD) Biomarkers for CHD Death
The overall objective of this research proposal is to determine whether the predictive value of using plasma concentrations of selected nutrient biomarkers of food intake determined using a single plasma sample either alone or in…
- Trial name
- WHI (NCT01864122)
- Where
- United States
- Volunteers
- 2,448 people, healthy volunteers welcome
- Sponsor
- Tufts University
Obesity
Vivamos Activos Fair Oaks Program for Weight Loss in Low Income Latinos
Physician-based primary care has thus far failed to address the obesity epidemic. In this randomized clinical trial of 200 obese patients with heart disease risk factors, the investigators will evaluate the impact of nurse and…
- Trial name
- VAFO (NCT01242683)
- Testing
- Vivamos Activos Fair Oaks Program
- Where
- 4 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
Coronary Heart Disease
Study of Herbal Formula Corresponding to Syndrome in Treating Post Percutaneous Coronary Intervention (PCI) Patients With Coronary Heart Disease (CHD)
We conduct this clinical trial to determine the effects of Xuefu Zhuyu capsule (based on TCM "Zheng Hou" theory) in helping recovery from coronary heart disease(CHD)after PCI and find out whether this kind of effecacy is much…
- Trial name
- NCT00817024
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Congenital Heart Disease (CHD)
Mesenchymal Stromal Cells for Infants With Congenital Heart Disease (MedCaP)
The proposed study will be a prospective, open-label, single-center, safety and feasibility phase 1 trial of allogeneic bone marrow-derived mesenchymal stromal cell (BM-MSC) delivery though cardiopulmonary bypass (CPB) using a…
- Trial name
- MedCaP (NCT04236479)
- Testing
- BM-MSC
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Catherine Bollard