Clinical trials: CHF - Congestive Heart Failure
End Stage Chronic Renal Failure, Congestive Heart Failure (CHF)
The FILTRATE Trial: High-Rate Ultrafiltration for Intravascular Congestion
The purpose of this study is to evaluate whether a personalized, high-rate fluid removal strategy guided by ultrasound is as safe and effective as the standard fluid removal rate for patients with advanced kidney disease who are…
- Conditions
- End Stage Chronic Renal Failure, Congestive Heart Failure (CHF), Intravascular Congestion, Fluid Overload
- Trial name
- FILTRATE (NCT07705269)
- Testing
- High-rate ultrafiltration, Standard fluid removal
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Congestive Heart Failure, Diastole
Aldosterone Antagonism in Diastolic Heart Failure
The primary purpose of this study is to determine whether eplerenone has a beneficial effect on improving exercise ability in patients with diastolic heart failure.
- Trial name
- NCT00108251
- Testing
- Eplerenone
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- US Department of Veterans Affairs
Congestive Heart Failure
CardioBreathApp vs IMT in Heart Failure
Heart failure (HF) is a systemic clinical syndrome defined as cardiac dysfunction, which causes inadequate blood supply to meet metabolic needs.
- Trial name
- CardioBreath (NCT06139653)
- Testing
- Moment 1: IMT. Moment 2 CardioBreath., Moment 1: CardioBreath and moment 2: IMT.
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Cardiovascular Diseases, Coronary Disease
Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease
This study will compare medical therapy with coronary bypass surgery and/or surgical ventricular reconstruction for patients with congestive heart failure and coronary artery disease (CAD).
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Failure, Congestive, Heart Diseases
- Trial name
- STICH (NCT00023595)
- Testing
- CABG surgery plus MED, Active Medication Alone, CABG plus MED and SVR
- Where
- United States
- Volunteers
- 2,136 people
- Sponsor
- Duke University
Heart Failure, Congestive
Effects of Carvedilol on Health Outcomes in Heart Failure
The purpose of our study was to determine if a strategy of starting a heart medication (Beta-blocker) before patients leave the hospital and then being seen by a nurse manager would reduce subsequent hospitalizations compared to…
- Trial name
- NCT00381030
- Testing
- carvedilol plus nurse management
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Denver Health and Hospital Authority
Right Ventricular Dysfunction, Right Heart Failure
Paceport Swan-Ganz Data Collection Study
RV dysfunction has been associated with increased mortality in the ICU and cardiac surgical patients. Thus, early identification of RV dysfunction at less severe stages will allow for earlier intervention and potentially better…
- Conditions
- Right Ventricular Dysfunction, Right Heart Failure, Congestive Heart Failure
- Trial name
- NCT04782154
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- Montreal Heart Institute
Heart Failure, Congestive
Clinical Reminders in Test Reports to Improve Guideline Compliance
Although beta-blockers are known to prolong survival for patients with reduced left ventricular ejection fraction, their use in the community and the VA is suboptimal.
- Trial name
- NCT00414401
- Testing
- Clinical Reminder
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- US Department of Veterans Affairs
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms
- Trial name
- PICSI-H (NCT04283994)
- Testing
- Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 756 people
- Sponsor
- University of Washington
Diabetes Mellitus, Type 2
Effects of Rosiglitazone on Plasma BNP Levels and Left Ventricular Dysfunction
The present study aimed to evaluate the effect of rosiglitazone treatment on cardiac function compared with metformin
- Trial name
- NCT00300911
- Testing
- Rosiglitazone(drug), cardiac adverse effects
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Baskent University
Congestive Heart Failure
Evaluation of the BodyGuardian End-to-end Remote Monitoring Platform in an Outpatient Heart Failure Population
We will evaluate the end to end remote monitoring system in a less controlled environment and concurrently develop the infrastructure to support the back end of the system
- Trial name
- R01-Aim2 (NCT01975402)
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Mayo Clinic
Chronic Heart Failure, Central Sleep Apnea
French Cohort Study of Chronic Heart Failure Patients With Central Sleep Apnoea Eligible for Adaptive Servo-Ventilation (PaceWave, AutoSet CS)
The purpose of FACE study is to provide in routine practice complementary long-term data on the mortality and morbidity of Chronic Heart Failure (CHF) patients with Central Sleep Apnea eligible for Adaptative Servo-Ventilation…
- Trial name
- FACE (NCT01831128)
- Testing
- ASV Treatment
- Where
- 18 sites in France
- Volunteers
- 509 people
- Sponsor
- ResMed
Heart Failure, Systolic
Patient and Physician Survey Determinants of Appropriate ICD Utilization
To better understand the reasons for underutilization of defibrillator therapy in selected populations, the investigators propose a study to assess heart failure patient knowledge and attitudes toward device therapy.
- Trial name
- NCT01514773
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- Todd M Koelling, MD
Outcome, Fatal
Oxygen Pulse and Its Curve Patterns in Male Patients With Heart Failure and Chronic Obstructive Pulmonary Disease With and in Healthy Men
Background: In non-invasive cardiopulmonary exercise testing (CPET), oxygen pulse (O2P) is defined as oxygen uptake divided by heart rate and is equal to the product of stroke volume and oxygen extraction by cells.
- Trial name
- NCT05189301
- Testing
- first pass study, cardiopulmonary exercise testing
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chung Shan Medical University
Heart Failure, Congestive
Dose Escalation Study of KW-3902 on Diuresis in Subjects With Congestive Heart Failure (CHF).
The purpose of this study is to evaluate the safety of KW-3902IV compared to placebo and to determine the diuretic effect of KW-3902IV compared to placebo in patients hospitalized with volume overload due to CHF who are…
- Trial name
- NCT00159627
- Testing
- KW-3902IV
- Where
- 10 sites in United States
- Volunteers
- 52 people
- Sponsor
- NovaCardia, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Acute Heart Failure, Congestive Edema
EMEPIC : Value of a Mobile Team of Cardiologist Using Echocardiography for Managing Patients With Acute Heart Failure
The aim of the study is to compare clinical management of patients with acute decompensation of heart failure, hospitalized in non cardiological ward, with the use of a mobile team including a cardiologist with portable…
- Conditions
- Acute Heart Failure, Congestive Edema, Cardiac Disease
- Trial name
- EMEPIC (NCT00568165)
- Testing
- Mobile team, Standard care
- Where
- France
- Volunteers
- 504 people
- Sponsor
- University Paris 7 - Denis Diderot
Heart Failure, Congestive
Renal Effects of Intrarenal Nesiritide
The impact of nesiritide in CHF is unclear, but it is possible that systemic vasodilation leads to adverse consequences even if the direct renal effects are positive.
- Trial name
- NCT00270829
- Testing
- nesiritide
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Maryland, Baltimore
Cancer, Congestive Heart Failure
Outlook Quality of Life Intervention
The purpose of this study is to determine whether discussions of life story, forgiveness, and future goals improve quality of life for patients with serious illness.
- Conditions
- Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00784095
- Testing
- Life completion and preparation, Attention Control
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Congestive Heart Failure
Multiparametric Heart Failure Evaluation in Internal Cardioverter Defibrillators (ICD) Patients
The Boston Scientific Energen family is capable of measuring the respiratory rate trend (RRT) on a daily basis and transmission of data via the Remote Monitoring technology.
- Trial name
- MULTITUDE-HF (NCT01501331)
- Testing
- CRTD or ICD (Energen)
- Where
- 2 sites in Italy
- Volunteers
- 180 people
- Sponsor
- University of Rome Tor Vergata
Mitral Valve Insufficiency, Heart Failure
Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure
Mitral regurgitation (MR), also known as mitral insufficiency, is a condition in which the heart's mitral valve, located between two of the heart's main chambers, does not firmly shut, allowing blood to leak backwards within the…
- Trial name
- SMMART-HF (NCT00608140)
- Testing
- Surgical mitral valvuloplasty with placement of annular ring (SMVR), Optimal medical therapy (OMT)
- Where
- 9 sites in United States, Canada
- Volunteers
- 2 people
- Sponsor
- Duke University
Congestive Heart Failure
Cardiovascular Diagnosis Using µ-Cor - an Interventional Pilot Trial
Subjects that are being treated at the Congestive Heart Failure clinic in Nazareth will be given the µ-Cor system to be added to their standard care, and randomized 1:1 to an interventional arm or a control arm.
- Trial name
- NCT02700191
- Testing
- uCor
- Sponsor
- Zoll Medical Corporation