Clinical trials: CHILD Syndrome
Human Immunodeficiency Virus (HIV)
Assessment of Group Peer Support to Children With HIV in Vietnam
This project aims to assess the effect of group peer support to children with HIV in relation to adherence, virological treatment failure as well as physical development.
- Trial name
- NCT02035969
- Testing
- Enhanced Treatment Support (ETS)
- Where
- Vietnam
- Volunteers
- 520 people
- Sponsor
- Karolinska Institutet
Pneumonia, Human Immunodeficiency Virus (HIV)
CPAP Improving Mortality for Pneumonia in African Children Trial
Pneumonia mortality rates in African countries like Malawi are high and increased further in children -exposed or infected with human immunodeficiency virus (HIV) as well as those that are severely malnourished or severely…
- Conditions
- Pneumonia, Human Immunodeficiency Virus (HIV), Malnutrition, Hypoxemia
- Trial name
- IMPACT (NCT02484183)
- Testing
- bubble continuous positive airway pressure (CPAP)
- Where
- Malawi
- Volunteers
- 646 people
- Sponsor
- Johns Hopkins University
Critical Illness
Use of In-Line Filtration in Critically Ill Children
The purpose of this study is to determine whether the use of in-line filtration shows any effect on the outcome of sepsis, systemic inflammatory response syndrome (SIRS), thrombosis, or organ failure in critically ill children…
- Trial name
- NCT00209768
- Testing
- Filter: NOE96E, ELD96E, NLF1E, TNA1E
- Where
- Germany
- Volunteers
- 821 people
- Sponsor
- Hannover Medical School
Fragile X Syndrome
Trial of Sertraline to Treat Children With Fragile X Syndrome
This study is a control trial of sertraline (Zoloft) in fragile X syndrome children aged 2 years to 5 years 8 months old. The trial is six months long, and each participant will receive a series of tests at both the beginning and…
- Trial name
- NCT01474746
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Randi J. Hagerman, MD
Fetal Alcohol Syndrome, Attention Deficit Hyperactivity Disorder (ADHD)
Open-Label Study of the Long Term Tolerability and Safety of Atomoxetine in Children With FASD and ADD/ADHD
Determine if atomoxetine is safe and well tolerated by children with fetal alcohol syndrome.
- Trial name
- B4Z-US-050 (NCT00418262)
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Oklahoma
HIV Infections
The Safety and Effectiveness of Zidovudine in the Treatment of HIV-Infected Children With Mild to Moderate Symptoms
To determine the safety and usefulness of zidovudine (AZT) for the treatment of children 3 months to 12 years of age. This study is designed to determine if children who are infected with HIV and who have a special type of lung…
- Trial name
- NCT00000990
- Testing
- Zidovudine
- Where
- 33 sites in United States
- Volunteers
- 224 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
A Double-Blind, Placebo-Controlled Trial To Evaluate Intravenous Gamma Globulin in Children With Symptomatic HIV Infection Receiving Zidovudine
To evaluate the clinical, immunologic, and virologic effects of oral zidovudine (AZT) plus intravenous immunoglobulin (IVIG) versus AZT plus placebo (albumin).
- Trial name
- NCT00000720
- Testing
- Globulin, Immune, Zidovudine
- Where
- 51 sites in United States, Puerto Rico
- Volunteers
- 250 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Epilepsy, Lennox-Gastaut Syndrome
A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults
To evaluate the efficacy of GWP42003-P as adjunctive treatment in reducing the number of drop seizures when compared with placebo, in participants with Lennox-Gastaut Syndrome (LGS).
- Trial name
- GWPCARE4 (NCT02224690)
- Testing
- GWP42003-P 20 mg/kg/day Dose
- Where
- 24 sites in United States, Netherlands and 1 more
- Volunteers
- 171 people
- Sponsor
- Jazz Pharmaceuticals
Down Syndrome
Delivering Early Intervention to Children With Down Syndrome
Children with Down syndrome (DS) are at risk for significant language and communication impairments. Enhancing the service delivery of early intervention for children with DS is a key research and policy issue given the…
- Trial name
- NCT03935620
- Testing
- Enhanced Milieu teaching
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Oregon Health and Science University
Dermatologic Disease, Epidermolysis Bullosa
The State of Sexual Development in Children With Inherited Epidermolysis Bullosa
The aim of the study is to determine the state of sexual development in patients with inherited epidermolysis bullosa; the study is planned to include boys and girls aged 8 to 18 years with a diagnosis of epidermolysis bullosa…
- Conditions
- Dermatologic Disease, Epidermolysis Bullosa, Epidermolysis Bullosa Simplex, Epidermolysis Bullosa Dystrophica
- Trial name
- NCT05033574
- Testing
- Biochemical study of hormone levels, Ultrasound examination, Radiography of the hands
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- National Medical Research Center for Children's Health, Russian Federation
Nephrotic Syndrome
Efficacy and Safety of Rituximab to That of Calcineurin Inhibitors in Children With Steroid Dependent Nephrotic Syndrome
Nephrotic syndrome in children is primarily caused by minimal change disease. Majority of these patients respond well to corticosteroids.
- Trial name
- NCT02438982
- Testing
- Tacrolimus, Rituximab
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Nilratan Sircar Medical College
Congenital Amegakaryocytic Thrombocytopenia, Diamond-blackfan Anemia
Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders
RATIONALE: Monoclonal antibodies, such as alemtuzumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread.
- Conditions
- Congenital Amegakaryocytic Thrombocytopenia, Diamond-blackfan Anemia, Leukemia, Myelodysplastic Syndromes
- Trial name
- NCT00301834
- Testing
- alemtuzumab, busulfan, cyclosporine
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Francisco
Candidiasis, Candidemia
Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal Infection
In this study we will measure the concentration of the drug called voriconazole which is used to fight infections caused by fungus in children who usually are cancer patients and have their immune system down.
- Trial name
- NCT00739934
- Testing
- voriconazole (Vfend)
- Where
- 14 sites in United States
- Volunteers
- 40 people
- Sponsor
- Pfizer
Genetic Disorder, Metabolic Disease
Studies of Children With Metabolic and Other Genetic Disorders
This study will provide medical evaluations for patients with known or suspected metabolic and genetic disorders. It will allow NICHD investigators and trainees experience in diagnosing, managing, and treating patients with…
- Trial name
- NCT00025870
- Where
- United States
- Volunteers
- 1,090 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Down Syndrome
Motor Intervention Whit the Intorus Tool on Children With Down Syndrome
The goal of this clinical trial is to test in people with down syndrome how does the INTORUS tool influence their psychomotor development.
- Trial name
- NCT05740046
- Testing
- INTORUS
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Extremadura
Anxiety
The Effect of Emotion Recognition and Empathy Focused Education Program Applied to Earthquake Survivors on Anxiety, Rumination and Post-traumatic Growth Levels of Children
Earthquakes cause increased mental health problems in the communities they hit. Few attempts have been made to develop effective psychological care strategies for earthquake survivors.
- Trial name
- NCT05815966
- Testing
- The effect of emotion recognition and empathy focused education program
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Sensenbrenner Syndrome
Sensenbrenner Clinical Study
Sensenbrenner syndrome, also known as cranioectodermal dysplasia (CED), is a rare autosomal-recessive disorder belonging to the ciliopathy group of diseases.
- Trial name
- Sensenbrenner (NCT04184531)
- Testing
- Medical Data Collect
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Hospices Civils de Lyon
Crohn's Disease, Nephrotic Syndrome
Glucocorticoid-induced Osteopenia in Children
The purpose of this study is to characterize the skeletal deficits and risk factors for impaired skeletal development in children requiring glucocorticoid therapy.
- Trial name
- NCT00289328
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pit and Fissure Caries, Glass Ionomer Cements
Glass Ionomer Sealant Versus Fluoride Varnish on Occlusal Caries Prevention
The current study compares the efficacy of glass ionomer fissure sealant versus topical application of 5% sodium fluoride varnish in prevention of occlusal caries among preschool children.
- Conditions
- Pit and Fissure Caries, Glass Ionomer Cements, Tooth, Deciduous, Child
- Trial name
- NCT04163354
- Testing
- 5% sodium fluoride varnish (NaF), Glass ionomer sealant (GIS)
- Where
- Hong Kong
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Down Syndrome, Congenital Heart Disease
Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)
The study objective is to compare neurodevelopmental (ND) and behavioral outcomes between children with Down syndrome (DS) who had complete atrioventricular septal defect (CAVSD) repair and children from the same clinical sites…
- Trial name
- CHILD-DS (NCT05312177)
- Testing
- Stanford Binet Intelligence Scales, Fifth Edition, Vineland Adaptive Behavior Scales Third Edition, Peabody Picture Vocabulary Test, Fifth Edition
- Where
- 14 sites in United States, Canada
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Carelon Research
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