Clinical trials: CIN
Cervical Cancer, Cervical Intraepithelial
Cervical Cancer Early Endpoints and Determinants
This study, conducted by the National Cancer Institute and the University of Oklahoma, will look for changes in cervix cells and other samples that may be signs of cervical disease.
- Conditions
- Cervical Cancer, Cervical Intraepithelial, Neoplasia, CIN
- Trial name
- NCT00339989
- Where
- United States
- Volunteers
- 3,013 people
- Sponsor
- National Cancer Institute (NCI)
Cervical Cancers, Vulvar Cancer
Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
To evaluate the safety and immunogenicity of the 9-valent Human Papillomavirus (Types 6, 11, 16, 18,31,33,45,52 and 58) Recombinant Vaccine (Hansenula Polymorpha) in Chinese Female Subjects Aged 9-45 Years.
- Conditions
- Cervical Cancers, Vulvar Cancer, Vaginal Cancer, CIN1
- Trial name
- NCT03676101
- Testing
- 9-valent HPV Recombinant Vaccine
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
HSIL, HSIL of Cervix
Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection
This study evaluates the use of topical ABI-1968 cream, in the treatment of cervical precancerous lesions in adult women.
- Conditions
- HSIL, HSIL of Cervix, High-Grade Squamous Intraepithelial Lesions, High-grade Cervical Intraepithelial Neoplasia
- Trial name
- NCT03239223
- Testing
- ABI-1968
- Where
- 9 sites in United States, Australia
- Volunteers
- 16 people
- Sponsor
- Antiva Biosciences
CIN
To Compare Intravenous and Oral Hydration of the Prevention for CIN in Elderly Patients Undergoing Intravenous CECT
To Compare Intravenous and Oral Hydration of the Prevention for Contrast-induced Nephropathy in Elderly Patients Undergoing Intravenous Contrast-enhanced Computed Tomography.
- Trial name
- CINOECT (NCT03872739)
- Testing
- enhanced computed tomography
- Where
- China
- Volunteers
- 1,368 people
- Sponsor
- Yu Danqing
CIN
Risk Factors,PREvention and OutComes for CI-AKI in PatientS undErgoing PCI at Intensive Care Unit(PRECISE-ICU)
A retrospective, observational study included all consecutively critically ill patients undergoing percutaneous coronary intervention(PCI) at intensive care unit (ICU) in Fujian Provincial Hospital from January 1st 2012 to…
- Trial name
- PRECISE-ICU (NCT03791606)
- Where
- China
- Volunteers
- 755 people
- Sponsor
- Kaiyang Lin
HPV16 Positive, Cervical Intraepithelial Neoplasia (CIN 2/3)
Therapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3)
This study will test the efficacy and safety of different routes of administration of a DNA vaccine in patients with HPV16+ CIN2/3. Subjects will be enrolled in one of six treatment groups.
- Trial name
- NCT00988559
- Testing
- DNA vaccination, Gene gun vaccine, intramuscular vaccination
- Where
- 3 sites in United States
- Volunteers
- 132 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
CIN 2/3, Cervical Cancer
Vvax001 Cancer Vaccine in (Pre) Malignant Cervical Lesions
Immune modulating effects and safety of Vvax001; different dosages will be tested in patients with a history of (pre) malignant cervical lesions.
- Trial name
- NCT03141463
- Testing
- Vvax001 therapeutic cancer vaccine
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- University Medical Center Groningen
CIN
Pap and HPVDNA Before and After Acetic Acid
This is a pilot study to assess the cell adequacy and quality of Pap smears and adequacy of samples for HPV DNA virus test done after application of 5%acetic acid in a VIA test.Normally a Pap test and HPV DNA test is performed…
- Trial name
- NCT02363244
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tata Memorial Hospital
Contrast Induced Nephropathy (CIN)
AVERT™ Clinical Trial for Contrast Media Volume Reduction and Incidence of CIN
The Osprey Medical AVERT System is indicated to reduce contrast media (CM) exposure to the kidneys during percutaneous coronary procedures thereby reducing the risk of contrast induced nephropathy (CIN).
- Trial name
- AVERT™ (NCT01976299)
- Testing
- AVERT
- Where
- 39 sites in United States, Australia and 1 more
- Volunteers
- 578 people
- Sponsor
- Osprey Medical, Inc
Human Papillomavirus, CIN 2
Natural History of HPV From Infection to Neoplasia in Adolescents and Young Women
The natural history of human papillomavirus (HPV) is most likely influenced by both innate and adaptive mucosal immunity. More specifically, we hypothesize that Toll like receptors (TLR) play an important role in cervical innate…
- Conditions
- Human Papillomavirus, CIN 2, CIN 3
- Trial name
- NCT01366742
- Where
- 2 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Contrast Media Induced Nephropathy (CIN)
Neutrophil Gelatinase-associated Lipocalin (NGAL) and Contrast Media Induced Nephropathy
Introduction: Patients with pre-existing impaired renal function are prone to develop acute contrast media induced nephropathy (CIN).
- Trial name
- NCT01292317
- Testing
- application of intravenous volume, oral fluid application
- Where
- Austria
- Volunteers
- 819 people
- Sponsor
- Medical University of Graz
CIN, Cervix Cancer
HPV E6/E7 mRNA Versus HPV DNA as Triage for Cervical Cancer Screening
AIM: To develop and standardize a cost effective methodology or algorithm for mRNA E6/E7 for HPV genotypes 16, 18, 31, 33 and 45 as compared to commercially available assays which can be incorporated to triage excess false…
- Trial name
- PODBT (NCT02116920)
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- Tata Memorial Hospital
Renal Adverse Events - Contrast Induced Nephropathy (CIN), Non-renal Adverse Events
Adverse Reactions to MR and CT-examinations (Enhanced and Unenhanced)
Rationale: Contrast agents are important tools for MR/CT- examinations, when it comes to diagnosing diseases. But despite their frequent use in Denmark, they are not free of serious and potentially fatal adverse reactions.
- Trial name
- NCT01132339
- Where
- Denmark
- Volunteers
- 1,467 people
- Sponsor
- Copenhagen University Hospital at Herlev
CIN, Cervical Cancer
New Gentle Biopsy Method of Cervix Lesions Using Superficial Curettage/Protocol ID: CX-CUR
It is to investigate to what extent a gentle tissue extraction of CIN lesions of the cervix will bring the same conclusion than the conventional cervix biopsy, but with less pain and morbidity, after patients were undergoing a…
- Trial name
- NCT01836588
- Testing
- conventional cervix biopsy
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Charite University, Berlin, Germany
Cervical Intraepithelial Neoplasia, Cervix Cancer
Study of the Diagnostic Efficacy of "Real Time" Niris 1300e Optical Coherence Tomography (OCT) Imaging System in the Management of Pre-invasive and Invasive Neoplasia of the Uterine Cervix
Optical Coherence Tomography (OCT) is a technology using harmless near infra-red light scatter to produce an image. Prior studies with OCT have demonstrated that OCT of the uterine cervix can differentiate between grades of…
- Conditions
- Cervical Intraepithelial Neoplasia, Cervix Cancer, Cervical Dysplasia, CIN
- Trial name
- PUSHOCTII (NCT01766284)
- Testing
- NIRIS 1300e
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Preventive Oncology International, Inc.
Cervical Cancer Cin Grade
New Methods of Distribution of a Self Sampler Kit for Cervical Cancer Screening
The opportunity of a home, self-collected sample, opens the chance to remove some of the barriers that may discourage women from participating to screening programmes or performing HPV (Human Papilloma Virus)-test.
- Trial name
- NMDSS2 (NCT01647724)
- Where
- Italy
- Volunteers
- 15,000 people
- Sponsor
- Azienda Sanitaria Locale 4, Teramo
Cervical Intraepithelial Neoplasia Grade 1 (CIN 1)
Diagnostic and Prognostic Value of p16INK4a Expression in Low Grade Squamous Intraepithelial Lesions of the Cervix.
P16INK4a has recently been described as a surrogate marker for HR-HPV associated squamous and glandular intraepithelial lesions of the cervix.
- Trial name
- NCT00343213
- Testing
- colposcopy
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Patient With Invasive Cervical Carcinoma, Patient With CIN Lesion
Evaluation of ELISA Assay on Human Papilloma Viruses (HPV) Infection Population
Cervical cancer the most frequent neoplasm and the fifth mortality rate of malignancies of the women in the world. It results in about 1,000 women in Taiwan and about 200,000 women worldwide dying of cervical cancer each year.
- Conditions
- Patient With Invasive Cervical Carcinoma, Patient With CIN Lesion, Patient With HPV Infected Patients Without Histopathologic Lesion, Normal Populations.
- Trial name
- NCT00673192
- Testing
- peripheral blood isolation
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
CIN
A Study of Two Iodinated Contrast Agents in Renally Impaired Patients Undergoing Cardiac Angiography
The main purpose of this study is to compare the incidence of contrast induced nephrotoxicity following the administration of Isovue or Visipaque in patients with moderate to severe renal insufficiency undergoing cardiac…
- Trial name
- NCT00289029
- Testing
- Iopamidol 370 mgI/mL
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Bracco Diagnostics, Inc