Clinical trials: CKD
Heart Failure, Chronic Obstructive Pulmonary Disease (COPD)
Epidemiological Cluster Evaluation in Patients Admitted to Internal Medicine, With at Least One of the Following Diagnoses: Heart Failure, COPD, Renal Failure. The FADOI IN-CluDiMI Study
Improved medical care has led to an increase in both the age and clinical complexity of patients admitted to Internal Medicine wards, characterized by multiple chronic diseases.
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease (COPD), Chronic Kidney Disease (CKD)
- Trial name
- IN-CluDiMI (NCT07660757)
- Where
- Italy
- Volunteers
- 4,500 people
- Sponsor
- Fadoi Foundation, Italy
Mafld in Ckd Patients
Association Betweenq MAFLD ( Metabolic Associated Fatty Liver Disease) and Chronic Kidney Disease
Assess frequency of renal affection in mafld
- Trial name
- NCT06135467
- Volunteers
- 150 people
- Sponsor
- Assiut University
Arthritis, Asthma
Mobility Assessment in Multi-morbidity
Multimorbidity (the presence of two or more coexisting long-term conditions) is a significant challenge facing the NHS, especially given UK's ageing population and the association with high levels of illness burden and healthcare…
- Conditions
- Arthritis, Asthma, Atrial Fibrillation, Bronchiectasis
- Trial name
- Multi-mobility (NCT06473168)
- Volunteers
- 55 people
- Sponsor
- Northumbria University
Chronic Kidney Disease
Supplemented Very Low Protein Diet and the Progression of Chronic Kidney Disease
This is a prospective single center randomized controlled trial with a total duration of 18 months aiming to evaluate the effectiveness and the safety of a very low protein diet supplemented with ketoanalogues of essential…
- Trial name
- KETOPROG (NCT02031224)
- Testing
- Conventional low protein diet, Very low protein diet supplemented with Ketosteril
- Where
- Romania
- Volunteers
- 250 people
- Sponsor
- Anemia Working Group Romania
Gout, Chronic Kidney Diseases
CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat
This trial will compare two effective therapies, allopurinol and febuxostat, to lower serum uric acid and therefore prevent further gout attacks. These therapies have never been compared at appropriate doses.
- Trial name
- NCT02579096
- Testing
- allopurinol capsule, 100-800 mg by mouth once daily, febuxostat tablet 40-120 mg by mouth once daily
- Where
- 23 sites in United States
- Volunteers
- 950 people
- Sponsor
- VA Office of Research and Development
End-Stage Renal Disease (ESRD) Chronic Kidney Disease, Stage 5 Renal Regeneration Anuria Diabetic Nephropathy, Anuria
Clinical Observation of Renal Function Reactivation Following a GRAS-Based Protocol in Patients With Chronic Kidney Disease and Long-Term Renal Arrest.
This observational study documents the impact of a specific oral protocol (based on FDA-GRAS ingredients) on patients with Stage 5 Chronic Kidney Disease (CKD).
- Conditions
- End-Stage Renal Disease (ESRD) Chronic Kidney Disease, Stage 5 Renal Regeneration Anuria Diabetic Nephropathy, Anuria, End-Stage Renal Disease (ESRD), Chronic Kidney Disease, Stage 5
- Trial name
- NCT07555327
- Testing
- CSR-CKD Oral Protocol
- Where
- Algeria
- Volunteers
- 8 people
- Sponsor
- Amar h Zireg
Chronic Kidney Insufficiency, Hypertension
Renal and Systemic Vascular Resistance in Chronic Kidney Disease (CKD)
Patients with reduced kidney function have a higher risk of heart disease and death. Studies have shown that blood vessels in patients with hypertension change with a decrease of lumen size and growth of the vessel wall.
- Conditions
- Chronic Kidney Insufficiency, Hypertension, Vasodilation
- Trial name
- RenVas (NCT01380717)
- Testing
- Beta-blocker, ACE-inhibitor, Calcium Channel Blockers, ACE-Inhibitor
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Chronic Kidney Diseases
External Validation of Clinical Prediction Tools for Estimating Salt and Potassium Intake in Nephrology Patients.
There is no validated self-questionnaire to assess salt and potassium intake in nephrology patients. Using Bayesian models, researchers developed clinical prediction tools to estimate salt and potassium intake in nephrology…
- Trial name
- UniverSel (NCT05783960)
- Testing
- administration questionary
- Where
- 5 sites in France
- Volunteers
- 629 people
- Sponsor
- Hospices Civils de Lyon
Chronic Renal Failure
Renal Sympathetic Modification in Patients With Chronic Renal Failure
The purpose of this study is to observe the incident of uremia and dialysis requirement after renal sympathetic modification using THERMOCOOL® catheter in patients with chronic renal failure, and evaluate safety and efficacy of…
- Trial name
- NCT01418560
- Testing
- renal sympathetic modification
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Renal Cell Carcinoma (Kidney Cancer), Renal Cell Carcinoma (RCC)
Efficacy and Safety of Finerenone and Empagliflozin in Delaying Renal Function Progression After Radical Nephrectomy in High-Risk CKD Patients: A Multicenter RCT
The goal of this clinical trial is to evaluate whether Finerenone and Empagliflozin, either alone or in combination, can delay the progression of renal function decline in patients at high risk for chronic kidney disease (CKD)…
- Conditions
- Renal Cell Carcinoma (Kidney Cancer), Renal Cell Carcinoma (RCC), Nephrectomy, Chronic Kidney Disease(CKD)
- Trial name
- EmFin-Nx (NCT06818305)
- Testing
- Finerenone (BAY 94-8862), Empagliflozin 10 mg
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Jinling Hospital, China
Chronic Kidney Disease, Patients Requiring Heparin Free Dialysis Treatments
HepZero:Heparin Free Dialysis With Evodial
The study hypothesis is that with Evodial in patients requiring heparin free dialysis, the heparin free treatment can be performed easily (without saline flushes or blood predilution) and is at least not inferior and maybe…
- Trial name
- NCT01318486
- Testing
- Heparin free dialysis technique, Evodial
- Where
- 10 sites in Belgium, Canada and 5 more
- Volunteers
- 265 people
- Sponsor
- Vantive Health LLC
Diabetic Kidney Disease, CAKUT
A Study of Participants With Chronic Kidney Disease Previously Treated With REACT
The purpose of this study is to evaluate the safety of supplemental REACT injections in participants with chronic kidney disease (CKD) who have previously received REACT treatment.
- Conditions
- Diabetic Kidney Disease, CAKUT, Chronic Kidney Diseases
- Trial name
- NCT05694169
- Testing
- Renal Autologous Cell Therapy (REACT)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Prokidney
Kidney Disease, Chronic
An Observational Study to Evaluate the Effectiveness of Mircera Treatment for Renal Anemia in Pre-dialysis Participants With Chronic Kideny Disease (CKD)
This observational trial will examine the efficacy and safety of Mircera for renal anemia in participants with stage III-IV CKD in daily clinical practice.
- Trial name
- NCT02547454
- Testing
- Methoxy polyethylene glycol-epoetin beta
- Where
- 12 sites in Slovenia
- Volunteers
- 393 people
- Sponsor
- Hoffmann-La Roche
Iron Deficiency Anemia, Chronic Kidney Disease
Iron Isomaltoside 1000 (Monofer®) in Non-Dialysis Dependent Chronic Kidney Disease and With Renal-Related Anaemia
The study is designed to determine the effects of an investigational drug Monofer in subjects with non-dialysis dependent chronic kidney disease (NDD-CKD) subjects and with iron deficiency anaemia (IDA).
- Trial name
- NCT01102413
- Testing
- Monofer, Iron Sulphate
- Where
- Denmark
- Volunteers
- 351 people
- Sponsor
- Pharmacosmos A/S
Chronic Kidney Disease, Inflammation
Anti-Inflammatory Effects of Rosiglitazone in Patients With Stage 4 and 5 Chronic Kidney Disease
The purpose of this study in patients with stage 4 and 5 chronic kidney disease is to determine whether rosiglitazone can reduce inflammatory markers and to investigate its effect on intima media thickness, calcification and…
- Trial name
- Hercules (NCT00169923)
- Testing
- rosiglitazone
- Where
- 2 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Leiden University Medical Center
Eye Diseases, Renal Impairment
Frequency Of Eye Problems In Type 2 Diabetes With Chronic Kidney Disease
This study evaluate the frequency and type of eye problem among Type 2 Diabetics with renal impairment and effect of renal impairment and haemodialysis on diabetic retinopathy
- Conditions
- Eye Diseases, Renal Impairment, Type2 Diabetes
- Trial name
- NCT03330054
- Testing
- fundoscope
- Volunteers
- 100 people
- Sponsor
- Mohammed Ramadan Abdallah
Chronic Kidney Disease (CKD)
Retrospective Analysis Assessing Clinical Risk Factors for Cardiovascular Events and Mortality and Development of a Risk Calculator in Chronic Kidney Disease Stage 5 on Dialysis
The purpose of this study is to evaluate which clinical and laboratory factors are associated with major adverse cardiovascular event (MACE) in chronic kidney disease (CKD) patients on dialysis.
- Trial name
- NCT04042350
- Testing
- Non-interventional
- Where
- Sweden
- Volunteers
- 2,773 people
- Sponsor
- Astellas Pharma Europe Ltd.
Chronic Kidney Disease, Hypertension
Early Identification and Action in CKD
Chronic kidney disease (CKD) is highly prevalent and associated with significantly increased risk of cardiovascular morbidity and end-stage renal disease.
- Trial name
- NCT02208674
- Testing
- Protocolized, pharmacist-delivered CKD Action Plan
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Geisinger Clinic
Chronic Kidney Disease, Unspecified Complication of Kidney Transplant
SodiUm Burden Lowered by Lifestyle Intervention: Self-Management and E-health Technology
The purpose of this study is to evaluate the effects and efficacy of dietary sodium restriction by mean of a new healthcare approach in patients with chronic kidney disease.
- Trial name
- SUBLIME (NCT02132013)
- Testing
- Intervention SUBLIME
- Where
- 4 sites in Netherlands
- Volunteers
- 99 people
- Sponsor
- University Medical Center Groningen
Chronic Kidney Diseases
Digital Dyadic Empowerment Program on Lifestyle Modification for Chronic Kidney Disease Management
The goal of this clinical trial is to find out if the Digital Dyadic Empowerment Program (DDEP) can help people with chronic kidney disease (CKD) and their care partners make healthy lifestyle changes.
- Trial name
- DDEP (NCT06756113)
- Testing
- Digital Dyadic Empowerment, Usual Care
- Where
- Taiwan
- Volunteers
- 208 people
- Sponsor
- National Cheng Kung University