Clinical trials: CKD - Chronic Kidney Disease
Renal Disease
OPTIMISE-CKD Study_current Clinical Landscape in Spain
OPTIMISE-CKD is a retrospective, observational study, using secondary data. The incidence of renal disease, including CKD, using eGFR or UACR laboratory measurements and diagnostic codes will be assessed in the study population.
- Trial name
- NCT06614712
- Testing
- Pre-pricing & reimbursement, incident renal disease cohort (study observation period 2020- 2024), Post-pricing & reimbursement, incident renal disease cohort (study observation period 2023-2024)
- Where
- Spain
- Volunteers
- 91,628 people
- Sponsor
- AstraZeneca
Focal Segmental Glomerulosclerosis, Chronic Kidney Diseases
Stem Cell Therapy for Patients With Focal Segmental Glomerulosclerosis
The purpose of this study is to analyze the safety, renal function, metabolic disorders and quality of life data in patients with focal segmental glomerulosclerosis treated with endovascular infusion of bone marrow derived…
- Trial name
- STEFOG (NCT02693366)
- Testing
- Bone marrow stem cell
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Chronic Renal Failure, Kidney Transplantation
Fluid Intake in Kidney Failure
Patients with renal impairment are usually advised to increase their fluid intake. There is currently, however, no evidence supporting this recommendation.
- Trial name
- NCT00842322
- Testing
- high fluid intake, normal fluid intake
- Where
- Austria
- Volunteers
- 76 people
- Sponsor
- Medical University of Vienna
Chronic Kidney Diseases
Quality of Life in Patients Transitioning to Home or In-Center Dialysis (QUALIFY CKD-to-HOME)
The goal of this study is to evaluate quality of life (QoL) and frailty trajectories from advanced chronic kidney disease (CKD) to after dialysis initiation, specifically comparing patients choosing home dialysis and in-center…
- Trial name
- NCT06458322
- Testing
- Home dialysis or In-Center dialysis
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Chronic Kidney Disease Requiring Chronic Dialysis
Immuno-nutrition Supplementation in Haemodialysis
The purpose of this pilot study is to test if an "immuno-nutrition" supplement can decrease inflammation in people on haemodialysis.
- Trial name
- NCT05700851
- Testing
- Immuno-nutrition supplement
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Nottingham
Chronic Kidney Failure, Congenital Heart Defects
Chronic Kidney Disease in Teenagers With Congenital Cardiac Disease
The prevalence of chronic kidney injury (CKD) following cardiac surgery during childhood is not known, but there is evidence of CKD in young adults.
- Trial name
- PRECARDIO (NCT01845402)
- Testing
- blood and urine samples
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critical Illness, Acute Kidney Injury
Skeletal Muscle Wasting and Renal Dysfunction After Critical Illness Trauma - Outcomes Study
This study aims to determine changes in kidney function during and after critical illness, comparing conventional creatinine based methods with the gold standard to accurately establish the presence of new or worsened chronic…
- Conditions
- Critical Illness, Acute Kidney Injury, Muscle Loss, Major Trauma
- Trial name
- KRATOS (NCT03736005)
- Testing
- Exposure of significant critical illness
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Queen Mary University of London
Non-ST-segment Elevation Myocardial Infarction, Chronic Kidney Disease
Optimised Procedure in Patients With NSTEMI and CKD
Aim of the study is the determination of the ideal timepoint for the treatment of patients with acute Non-ST-segment Elevation Myocardial Infarction (NSTEMI) and an acute or chronic kidney disease (CKD) with a GRACE score < 140.
- Trial name
- NSTEMI-CKD (NCT02543177)
- Testing
- coronary angiography, ischemic precondition, prior kidney irrigation
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- RWTH Aachen University
End Stage Chronic Renal Failure, Chronic Kidney Disease (Stages 4 and 5)
Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage
The goal of this clinical trial is to test how storage temperature of deceased donor kidneys affects kidney function after transplant in adult patients receiving a kidney transplant.
- Conditions
- End Stage Chronic Renal Failure, Chronic Kidney Disease (Stages 4 and 5), Kidney Transplantation Recipients
- Trial name
- NCT07385651
- Testing
- 10˚C deceased donor kidney storage using Traferox XPort
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Kidney Disease, Heart Failure With Reduced Ejection Fraction (HFrEF)
Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure
This study compares the effects of once-daily versus twice-daily ramipril dosing on renal function in chronic kidney disease (CKD) patients with heart failure with reduced ejection fraction (HFrEF).
- Trial name
- NCT07259512
- Testing
- Ramipril
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Evi Liliek Wulandari
Metabolic Acidosis, CKD
Explorative Study to Investigate the Acid-base Response to Sodium and Potassium Salts in Patients With Chronic Kidney Disease.
With this research the investigators want to study how patients with chronic kidney disease respond to different sodium- and potassium salts.
- Conditions
- Metabolic Acidosis, CKD, Electrolyte and Fluid Balance Conditions
- Trial name
- 5S (NCT06237712)
- Testing
- Dietary supplement consisting of 40 mmol/daily of potassium chloride, Dietary supplement consisting of 40 mmol/daily of potassium gluconate, Dietary supplement consisting of 40 mmol/daily of potassium bicarbonate
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Erasmus Medical Center
Influenza, Vaccine Reaction
Effectiveness of Trivalent Influenza Vaccine (TIV) in Type 2 Diabetes Mellitus (T2DM) Patients With and Without Complications of Chronic Kidney Disease (CKD)
This study assesses the effectiveness of the seasonal flu vaccine in individuals with Type 2 Diabetes Mellitus (T2DM) with and without Chronic Kidney Disease (CKD), as well as in healthy individuals.
- Conditions
- Influenza, Vaccine Reaction, Diabetes Mellitus, Chronic Kidney Diseases
- Trial name
- NCT06252051
- Testing
- Trivalent Influenza Vaccine
- Where
- Indonesia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Anemia Associated With Chronic Kidney Disease
Investigating the Efficacy, Safety and PK of Roxadustat (FG-4592) for Treatment of Anemia in Pediatric Patients With CKD
This open-labeled, multicenter study is designed to evaluate the efficacy, safety and PK/PD of roxadustat in ESA-naïve and ESA-treated pediatric patients with CKD Stages 3, 4, and 5, as well as end-stage renal disease (ESRD) who…
- Trial name
- NCT04621331
- Testing
- Roxadustat
- Where
- 4 sites in United States
- Sponsor
- Kyntra Bio
Cushing Syndrome
Appropriate Limit Value for 1 mg DST in Patients With Chronic Renal Failure
In this study, we aimed to determine a specific cut-off value for 1mg DST to prevent false positivity usually seen in CRF patients according to the standard cut-off value of 1.8 mcg/dl.
- Trial name
- NCT05568602
- Testing
- Dexamethasone suppression test
- Where
- Turkey (Türkiye)
- Volunteers
- 1,034 people
- Sponsor
- Marmara University
Growth Hormone Deficiency, Turner Syndrome
Long-term Safety and Effectiveness of Growth Hormone With GHD, TS, CRF, SGA , ISS and PWS in Children
The purpose of this study is to evaluate the long-term safety and effectiveness of growth hormone (Eutropin Inj./Eutropin plus Inj.) treatment with GHD (Growth Hormone Deficiency), TS (Turner Syndrome),CRF (Chronic Renal…
- Conditions
- Growth Hormone Deficiency, Turner Syndrome, Chronic Renal Failure, Small for Gestational Age
- Trial name
- LGS (NCT01604395)
- Where
- South Korea
- Volunteers
- 6,000 people
- Sponsor
- LG Chem
Renal Anaemia
Biosimilar Erythropoietin in Anaemia Treatment (Correction Phase Study)
This study is aimed to comprehensively establish the biosimilarity/bioquivalence in EPIAO® and EPREX® in terms of 52-week comparisons in efficacy,safety and immunogenicity.The targeted population is anaemia patients with chronic…
- Trial name
- BEAT_001 (NCT02522975)
- Testing
- EPIAO®, EPREX®
- Where
- 8 sites in Thailand
- Volunteers
- 16 people
- Sponsor
- Shenyang Sunshine Pharmaceutical Co., LTD.
Limb Ischemia, Critical
Role and Outcome of Endovascular Revascularization of Chronic Limb Ischaemia
identify the safety and efficacy of percutaneous transluminal angioplasty in critical limb ischaemia patients with chronic kidney dieases
- Trial name
- NCT05643378
- Volunteers
- 100 people
- Sponsor
- Mahmoud Abdelmohsen Mostafa Osman
Chronic Kidney Disease Requiring Chronic Dialysis
Orthostatic Hypotension and Blood Pressure Variability in Persons Undergoing Hemodialysis
High blood pressure is a risk factor for end-stage renal disease and is common in patients undergoing maintenance hemodialysis. Intradialytic hypotension is associated with an adverse prognosis.
- Trial name
- NCT06348589
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Vrinnevi Hospital
Overweight, Obesity
A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes
We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or without type 2 diabetes (T2D). The study will last about 56 weeks and include up to 12 visits.
- Conditions
- Overweight, Obesity, Chronic Kidney Disease, Type 2 Diabetes
- Trial name
- TREASURE-CKD (NCT05536804)
- Testing
- Tirzepatide
- Where
- 27 sites in United States, Austria and 4 more
- Volunteers
- 134 people
- Sponsor
- Eli Lilly and Company
Chronic Kidney Diseases
A Minute for my Kidneys
The purpose of this study is to evaluate the effectiveness of the "One Minute for My Kidneys" program in reducing the time it takes for participants with stage V chronic kidney disease and other comorbidities to begin dialysis.
- Trial name
- UMPMR-V (NCT07869849)
- Testing
- Dialysis
- Where
- France
- Volunteers
- 312 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
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