Clinical trials: CKD - Chronic Kidney Disease
Chronic Kidney Diseases
Peoples Perceptions of Forms of Renal Replacement Therapy
Chronic kidney disease (CKD) causes symptoms and potential loss of independence. These effects are increased as the disease progress to endstage renal disease (ESRD), particularly when external intervention (i.e.
- Trial name
- NCT04427800
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Portsmouth
Chronic Kidney Disease
Effect of Low Frequency Ultrasound on Kidney Function
The purpose of this study is to find out what effect, if any, Low Frequency Therapeutic Ultrasound (LOTUS) has on kidney function in patients with chronic kidney disease.
- Trial name
- NCT02026544
- Testing
- Low Frequency Therapeutic Ultrasound
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sonogenix
Chronic Kidney Disease 5D
Bio-ADM as a Biomarker of Refilling in Chronic Hemodialysis Patient
Aim of this study is to evaluate in a population of chronic kidney disease patients on dialysis (Stage 5D) the predictive value of bio-adrenomedullin (bio-ADM) level on vascular refilling rate.
- Trial name
- REFILBIOADM (NCT05339009)
- Testing
- BioADM determination in plasma
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Disease
Low Phosphate Diets in Patients With Early Stages of Chronic Kidney Disease
The purpose of this study is to learn more about how the kidneys control the blood levels of phosphorus in patients with early chronic kidney disease.
- Trial name
- NCT00438932
- Testing
- Lanthanum Carbonate, Low Phosphorus Diet, Unrestricted Phosphorus Diet
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Massachusetts General Hospital
Chronic Kidney Disease, End Stage Kidney Disease
Reduction of Mortality Prior to and During the First 90 Days of Dialysis Through a Renal Rehabilitation Program
The mortality rate of treated patients with end stage renal disease(ESRD)is 22 deaths patient-years at risk in 2006. Incident patients with ESRD are most vulnerable within the first 90 days of dialysis, with an annualized…
- Conditions
- Chronic Kidney Disease, End Stage Kidney Disease, Cardiovascular Disease
- Trial name
- NCT00792454
- Testing
- exercise training
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- MaineHealth
Liver Transplantation, Chronic Renal Insufficiency
Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver Transplantation
A prospective, non-randomized two stage monocentric phase II clinical trial to evaluate a de-novo calcineurin-inhibitor (CNI)-free immunosuppressive regimen based on induction therapy with anti-CD25 monoclonal anti-body…
- Trial name
- CILT (NCT00890253)
- Testing
- Basiliximab (Simulect), Myfortic, everolimus
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- Armin Goralczyk
Renal Insufficiency, Chronic, Potassium Depletion
Potassium Supplementation in CKD
The current high-sodium, low-potassium diet contributes to the high prevalence of high blood pressure (hypertension). Indeed, the anti-hypertensive effects of potassium supplementation are well-established.
- Conditions
- Renal Insufficiency, Chronic, Potassium Depletion, Hypertension, Hyperkalemia
- Trial name
- K+ in CKD (NCT03253172)
- Testing
- Potassium Chloride, Potassium Citrate
- Where
- 4 sites in Netherlands
- Volunteers
- 532 people
- Sponsor
- Erasmus Medical Center
Anemia Associated With Chronic Kidney Disease
Investigating the Efficacy, Safety and PK of Roxadustat (FG-4592) for Treatment of Anemia in Pediatric Patients With CKD
This open-labeled, multicenter study is designed to evaluate the efficacy, safety and PK/PD of roxadustat in ESA-naïve and ESA-treated pediatric patients with CKD Stages 3, 4, and 5, as well as end-stage renal disease (ESRD) who…
- Trial name
- NCT04621331
- Testing
- Roxadustat
- Where
- 4 sites in United States
- Sponsor
- Kyntra Bio
Chronic Kidney Disease, Chronic Renal Failure
A Phase 3 Study Comparing the Effects of Intravenous Epoetin Hospira and Epoetin Alfa [Epogen] (Amgen) in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
The purpose of this study is to demonstrate therapeutic equivalence of IV Epoetin Hospira compared to IV Epogen (Amgen), based on maintenance of Hb levels and study drug dose requirements in patients treated for anemia associated…
- Trial name
- AiME - 01 (NCT01473407)
- Testing
- Epoetin Hospira, Epogen (Amgen)
- Where
- 85 sites in United States, Puerto Rico
- Volunteers
- 612 people
- Sponsor
- Pfizer
Hemodialysis Chronic Kidney Disease Patients With Anemia
A Study of Intermittent Oral Dosing of ASP1517 in Hemodialysis Chronic Kidney Disease Patients With Anemia
The objective of this study is to evaluate the safety and efficacy of ASP1517 compared to darbepoetin alfa in hemodialysis chronic kidney disease patients with anemia.
- Trial name
- NCT02952092
- Testing
- roxadustat, Darbepoetin alfa
- Where
- 57 sites in Japan
- Volunteers
- 303 people
- Sponsor
- Astellas Pharma Inc
Chronic Renal Insufficiency
Redox State in the Course of Chronic Renal Insufficiency and Hemodialysis: Implications in Morbimortality
The influence of hemodialysis on oxidative stress, endothelial activation, inflammation and on the redox state of lymphocytes should be clarified as well as the putative relationships between all these parameters.
- Trial name
- NCT00684034
- Testing
- Sampling of blood
- Where
- France
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Chronic Kidney Diseases
Resistant Starch Prebiotic Effects in Chronic Kidney Disease
In patients with Chronic Kidney Disease (CKD), there is a buildup of nitrogenous uremic toxins of gut microbiome origin, which can contribute to uremic symptoms, reduced quality of life, and earlier progression to dialysis.
- Trial name
- ReSPECKD (NCT04961164)
- Testing
- Resistant Potato Starch, Corn Starch, Corn Starch, Resistant Potato Starch
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Chronic Kidney Diseases, Dementia
BRINK (BRain In Kidney Disease) Memory Study 2.0
In this study, the investigators will be looking at results of tests of memory and thinking and daily activities in a group of people without known chronic kidney disease (CKD) , and a group of CKD patients, and follow the…
- Conditions
- Chronic Kidney Diseases, Dementia, Dementia, Vascular, Stroke
- Trial name
- BRINK (NCT04975464)
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Anne Murray
Anemia of Chronic Kidney Disease
Roxadustat for Anemia in Patients With CKD
A number of RCT studies have shown the safety and effectiveness of oral Roxadustat in the treatment of renal anemia, but there is a lack of evidence from cohort studies.
- Trial name
- NCT04502537
- Testing
- Roxadustat, erythropoietin
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shenzhen Second People's Hospital
Metabolic Acidosis
Correction of Metabolic Acidosis in End Stage Renal Disease (ESRD)
The investigators want to evaluate whether an original action based on the administration of alkali (mainly sodium bicarbonate) is able to significantly modify renal death and to reduce mortality due to cardiovascular events.
- Trial name
- UBI (NCT01640119)
- Testing
- Bicarbonate
- Where
- 2 sites in Italy
- Volunteers
- 728 people
- Sponsor
- Azienda Sanitaria ASL Avellino 2
Chronic Kidney Disease
Canadian Study of Prediction of Risk and Evolution to Dialysis, Death and Interim Cardiovascular Events Over Time
This study will follow 2500 prevalent Chronic Kidney Disease (CKD) patients with Glomerular Filtration Rate (GFR) from 15-45 ml/min for 30 months with serial measurements every 6 months and subsequent annual chart review up to 60…
- Trial name
- CanPREDDICT (NCT00826319)
- Where
- 25 sites in Canada
- Volunteers
- 2,602 people
- Sponsor
- University of British Columbia
Kidney Disease, Chronic, End Stage Kidney Disease
An Observational Study of Patients With Chronic Kidney Disease
TARGET-KIDNEY is an observational research study to conduct a comprehensive review of outcomes for patients with chronic kidney disease (CKD) and end-stage renal disease (ESKD).
- Trial name
- NCT05774392
- Testing
- Observational
- Sponsor
- Target PharmaSolutions, Inc.
Diabetes Mellitus, Type 2, Renal Insufficiency, Chronic
Comparative Effectiveness of Metformin for Type 2 Diabetes With Chronic Kidney Disease
This is a proposal for a retrospective observational study of the safety of metformin use in patients with chronic kidney disease, compared to other commonly used diabetes drugs.
- Trial name
- NCT03921242
- Testing
- Metformin, Sulfonylurea, DPP-4 inhibitor
- Where
- 2 sites in United States
- Volunteers
- 4,888 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
CKD, Renal Insufficiency Chronic
The CPH-MBD Cohort Dietary Substudy - Comparison of Methods for Dietary Registrations
The aim of the study is to assess the association between the calcium and phosphorus balance and the stage of kidney disease measured by creatinine clearence in patients with chronic kidney disease stage 4 and 5.
- Conditions
- CKD, Renal Insufficiency Chronic, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder, Pre-dialysis
- Trial name
- NCT07312981
- Where
- 2 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- University of Copenhagen
Chronic Kidney Diseases
everlinQ Endovascular Access Systems Enhancements (EASE-2) Study
Prospective, single-center study to evaluate the everlinQ endoAVF System when used to create an endoAVF in hemodialysis patients.
- Trial name
- NCT03708562
- Testing
- everlinQ endoAVF System
- Where
- Paraguay
- Volunteers
- 24 people
- Sponsor
- C. R. Bard
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