Clinical trials: CKD - Chronic Kidney Disease
Chronic Kidney Disease
Efficacy and Safety of Abelmoschus Manihot for Chronic Kidney Disease
Huangkui Capsule is a single medicament of traditional Chinese medicine consists of Abelmoschus manihot and has been widely used to treat kidney disease.
- Trial name
- NCT02231138
- Testing
- Abelmoschus manihot (AM)
- Where
- 78 sites in China
- Volunteers
- 1,600 people
- Sponsor
- Chinese PLA General Hospital
Diabetes with Diabetic Chronic Kidney Disease (Diagnosis)
Flash Glucose Monitoring in Reduction of Hypoglycaemia in Diabetic Patients with Chronic Kidney Disease
This will be a single centre study at the Prince of Wales Hospital, Hong Kong. Patients will be identified from an existing registry of diabetes patients with CKD.
- Trial name
- NCT04016155
- Testing
- Abbott FreeStyle Libre, Patient Own SMBG
- Where
- Hong Kong
- Volunteers
- 94 people
- Sponsor
- Chinese University of Hong Kong
Chronic Kidney Disease Mineral and Bone Disorder
Artificial Intelligence: a New Alternative to Analyse CKD-MBD in Hemodialysis
The regulation of calcium, phosphate and parathyroid hormone in hemodialysis is complex and each parameter is not independently regulated.
- Trial name
- NCT02697578
- Where
- Spain
- Volunteers
- 197 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Focus Chronic Kidney Disease With Hypertension
Exercise as an Adjunct Therapy to Reduce Blood Pressure in Chronic Kidney Disease
The general objective of the study is to investigate the effect of regular aerobic exercise on resting and 24-hr blood pressure levels in men and women with stage 3-4 kidney disease and hypertension.
- Trial name
- PACE (NCT02112825)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Chronic Kidney Diseases
Respiratory Training in Hemodialysis Patients
Patients with chronic kidney disease in hemodialysis have complex syndrome with diverse effects on cardiovascular, nervous, respiratory, musculoskeletal, immune and endocrine-metabolic systems.
- Trial name
- NCT03153124
- Testing
- Respiratory muscle training
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
A Disease Area Study on the Awareness and Perceptions of Systemic Inflammation and hsCRP as a biomARKer in Patients With ASCVD and CKD in China Among Cardiologists and Nephrologists
This is a survey-based study with the objective to understand the awareness, perceptions and potential clinical management patterns among Chinese cardiologists and nephrologists towards the role of systemic inflammation in…
- Trial name
- SPARK-CVD (NCT06589791)
- Testing
- No treatment given
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Novo Nordisk A/S
Chronic Kidney Disease, Congestive Heart Failure
Peritoneal Ultrafiltration to Treat Congestive Heart Failure
The purpose of this study is to determine whether the treatment of peritoneal ultrafiltration can improve survival and quality of life of refractory congestive heart failure with special accent on preserving residual renal…
- Trial name
- NCT02829450
- Testing
- peritoneal ultrafiltration
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Soroka University Medical Center
Female With Osteoporosis and Chronic Kidney Disease
Study Evaluating Denosumab on Bone and Vascular Metabolism in Osteoporotic Chronic Kidney Disease
Aim of this study is to evaluate in a population of old osteoporotic chronic kidney disease females the effect of denosumab: on bone mineral density (femoral T-score) at 24 months on bone mineral density evolution (femoral…
- Trial name
- HDENO (NCT02792413)
- Testing
- Denosumab
- Where
- 9 sites in France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Diseases, Hyperphosphatemia
A Study to Evaluate Safety and Efficacy of AP-306 in Hyperphosphatemia Patients
The goal of this clinical trial is to learn about the following questions in the patients receiving maintenance hemodialysis with elevated blood phosphorus: How much effect AP-306 has assessed by blood phosphorus lowering; How…
- Trial name
- NCT05764590
- Testing
- AP-306, Sevelamer Carbonate
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Alebund Pharmaceuticals
Chronic Kidney Disease(CKD), Myosteatosis
The Effect of the Nutraceutical (-)- Epicatechin on Myosteatosis in Patients With Advanced CKD
Some foods have components that can prevent and treat some diseases and provide beneficial effects for health. These components naturally occurring in foods are called nutraceuticals.
- Conditions
- Chronic Kidney Disease(CKD), Myosteatosis, Mitochondrial Dysfunction, Muscle Function
- Trial name
- EPIC-CKD (NCT06631820)
- Testing
- Epicatechin extract
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
Diabetes Mellitus, Type 2, Chronic Kidney Disease
Carotid Doppler Screening for Subclinical Atherosclerosis in Diabetic CKD Patients.
This study is being done at Assiut University to look for early signs of hardening of the arteries (atherosclerosis) in people who have both diabetes and chronic kidney disease (CKD).
- Conditions
- Diabetes Mellitus, Type 2, Chronic Kidney Disease, Atherosclerosis
- Trial name
- DiCKD-CAROTID (NCT07266220)
- Volunteers
- 96 people
- Sponsor
- Abdallah Ali Mohammed
Chronic Kidney Diseases
Effects of Cinnamomum Supplementation in Chronic Kidney Disease Patients
Patients with chronic kidney disease (CKD) experience many complications related to inflammation and oxidative stress that are closely related to the progression of kidney failure and increased mortality.
- Trial name
- NCT06286735
- Testing
- cinnamomum
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Chronic Kidney Diseases
A Study of Patients With Chronic Kidney Disease to Assess the Safety of a Single Dose of COR-001
This is a randomized, double-blind, placebo-controlled trial designed to evaluate the safety, pharmacokinetics, and pharmacodynamic effects of a single dose of the study drug or placebo administered subcutaneously to patients…
- Trial name
- COR-001-SC1 (NCT03126318)
- Testing
- COR-001
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Colorado, Denver
Chronic Renal Failure, Dialysis
The Use of Electrical Bioimpedance to Evaluate Dry Weight in Patients With Chronic Renal Failure in Hemodialysis
INTRODUCTION: Accurate estimation of dry weight (DW) is an important and difficult problem in clinical practice. DW is defined as the lowest weight after hemodialysis (HD) where the patient will not develop symptoms of…
- Conditions
- Chronic Renal Failure, Dialysis, Dry Weight, Blood Pressure
- Trial name
- NCT03232515
- Testing
- To estimate the dry weight of patients with chronic renal failure under hemodialysis treatment using BIVA
- Where
- Mexico
- Volunteers
- 38 people
- Sponsor
- Universidad de Sonora
Kidney Disease, Chronic Kidney Disease
Study Evaluating Darbepoetin Alfa in Subjects With Chronic Kidney Disease (CKD) Receiving Dialysis
The proposed study is designed to test a novel dosing paradigm that would facilitate the treatment of anemia in CKD patients on dialysis.
- Trial name
- NCT00096915
- Testing
- Darbepoetin Alfa
- Volunteers
- 110 people
- Sponsor
- Amgen
Kidney Disease, Kidney Transplantation
BIOmarkers Before and After Kidney Transplantation
In clinical nephrology, the search for urinary, blood and tissue biomarkers of specific kidney diseases is an important goal. In recent years, the use of these biomarkers has made it possible to diagnose many renal diseases that…
- Trial name
- PROBIOT (NCT06810258)
- Testing
- Blood sample during native kidney biopsy, Blood sample during renal graft biopsy, Urine sample during renal graft biopsy
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Insufficiency, Chronic, Nephrotic Syndrome
Rituximab Combined With MSCs in the Treatment of PNS (3-4 Stage of CKD)
Primary nephrotic syndrome(PNS) is a group of clinical symptoms caused by a variety of factors, including immune,environmental, genetic, et al.
- Trial name
- CKD (NCT02966717)
- Testing
- Rituximab, conventional therapy, Mesenchymal stem cells
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Zhujiang Hospital
Transplant Recipient (Kidney), Primary Kidney Transplantation
Posttranslationally Modified Fetuin-A in Urine as a Marker for Renal Dysfunction (Patients With Chronic Kidney Disease - With or Without Kidney Transplantation).
Kidney transplantation is the preferred treatment method for patients with chronic kidney disease. Standard parameters (estimated glomerular filtration, albuminuria) of renal function detection are limited by many factors…
- Trial name
- (uPTM-FetA) (NCT06950931)
- Testing
- uPTM-FeA
- Where
- Slovakia
- Volunteers
- 86 people
- Sponsor
- University Hospital, Martin
Chronic Kidney Disease(CKD), Nocturnal Hypertension
Protecting Renal Function in Chronic Kidney Disease Patients with Isolated Nighttime Hypertension
Hypertension guidelines recommend the application of ambulatory blood pressure monitoring in the diagnosis and treatment of patients with hypertension.
- Trial name
- PRECISE (NCT06780865)
- Testing
- Antihypertensive treatment with Arotinolol or Amlodipine or Clonidine
- Volunteers
- 200 people
- Sponsor
- Shanghai Institute of Hypertension
Kidney Disease, Chronic
Oral Findings in a Group of Egyptian Pediatric Patients at Endstage Renal Disease
In Egypt, the prevalence of end stage renal disease in pediatric population has never been estimated on a national scale. The patients at end stage renal disease encounter oral and dental problems that emphasize regular and…
- Trial name
- NCT03590067
- Testing
- Questionnaire
- Volunteers
- 150 people
- Sponsor
- Cairo University
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