Clinical trials: CKD - Chronic Kidney Disease
Chronic Kidney Disease
Study of the Compliance With Phosphorus Restricted Diet and Phosphate Binder Therapy in Hemodialysis Patients
Hyperphosphatemia is a common and severe complication in chronic kidney disease patients treated with hemodialysis. A phosphate restricted diet and oral phosphate binders are the cornerstones in the prevention and treatment of…
- Trial name
- NCT01509027
- Testing
- education by DVD, Standard care, Education by DVD and dietician
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Renal Failure, Sleep Disorder
Light Therapy on Sleep Quality in Dialysis Patients
Sleep disorders are common in dialysis patients. At present, the management of insomnia in patients with chronic renal failure is not significantly different from that of the general population, which focuses on the management of…
- Conditions
- Chronic Renal Failure, Sleep Disorder, Hemodialysis, Light Therapy
- Trial name
- LUMIDIAL (NCT04089397)
- Testing
- Light Therapy
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Chronic Kidney Failure, End-stage Renal Disease
Fosrenol and Phosphorus Balance - Lanthanum Carbonate
Positive phosphorus balance and hyperphosphatemia (increased serum phosphorus levels) are very common complications of people with advanced chronic kidney disease (i.e., stage 5 CKD), including chronic dialysis patients, and are…
- Conditions
- Chronic Kidney Failure, End-stage Renal Disease, Disorders Associated With Peritoneal Dialysis
- Trial name
- NCT01581996
- Testing
- lanthanum carbonate
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Radiocontrast-induced Nephropathy
Mechanisms for the Effect of Acetylcysteine on Renal Function After Exposure to Radiographic Contrast Material
Millions of people receive radiographic contrast material for investigations like CT and coronary angiography. While considered safe in healthy patients, it can cause acute renal impairment.
- Trial name
- NCT00558142
- Testing
- Acetylcysteine, Visipaque 320
- Where
- United Kingdom
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Chronic Kidney Disease, Cardiovascular Diseases
SEDentary Lifestyle, Mortality and Major Adverse Clinical Outcomes in Chronic KIDney Disease
The goal of this study is to learn if a simple home exercise program can benefit patients with advanced chronic kidney disease. There is also an observational part of the study without an exercise program.
- Conditions
- Chronic Kidney Disease, Cardiovascular Diseases, Frailty
- Trial name
- SEDKID (NCT06935786)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Where
- 3 sites in Finland
- Volunteers
- 400 people
- Sponsor
- Turku University Hospital
Ferric Compounds, Magnetic Resonance Angiography
Ferumoxytol Enhanced Magnetic Resonance Angiography in Chronic Kidney Disease
Conventional vascular imaging techniques are often either contra-indicated in chronic kidney disease (CKD) patients due to their relative invasiveness, risks and cost.
- Conditions
- Ferric Compounds, Magnetic Resonance Angiography, Vascular Grafting, Arteriovenous Fistula
- Trial name
- FeMRA in CKD (NCT02997046)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Sokratis Stoumpos
Chronic Kidney Diseases, Protein-Energy Malnutrition
Effect of a Specialized Oral Supplement on Nutritional Status and Quality of Life in Non-dialysis CKD
Patients whit chronic kidney disease (CKD) there is a high prevalence of nutritional disorders and negative changes in body composition, which is strongly associated with an increased risk of morbidity and mortality.
- Trial name
- NCT06576479
- Testing
- Nutritious Shake, Nutritional counseling
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- NIN Institute
Chronic Kidney Disease, Stage 5, Sarcopenia
Effects of Intradialytic Exercise on Muscle Oxygenation and Dialysis Adequacy
This randomized controlled trial will evaluate the effects of a 12-week intradialytic combined exercise program, consisting of aerobic and resistance training, in patients with stage 5 chronic kidney disease receiving maintenance…
- Trial name
- NCT07151742
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
Chronic Kidney Disease, Hypertension
Lifestyle Intervention In CKD
This research study will test whether a 12-week healthy lifestyle program offered through a cardiac rehabilitation center can help lower blood pressure and improve kidney health in adults with advanced chronic kidney disease.
- Trial name
- CKD-LIFE (NCT07633145)
- Testing
- Multi-component lifestyle intervention, Usual Care Control
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Duke University
Uremic Toxin
Evaluation of Protective Effect of Activated Charcoal and Probiotic Against Progression of Chronic Kidney Disease
Investigate the nephroprotective effect of Activated Charcoal and Probiotic in limiting the progression of renal impairment in patients with chronic kidney disease and improving of renal function test and phosphate level.
- Trial name
- NCT05540431
- Testing
- Activated Charcoal, Probiotic, No intervention
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Waleed Khaild Rahman Kareem Al-kabi
Chronic Kidney Disease, Dialysis
A Phase III, Multi-Centre, Randomised, Placebo-Controlled Study in Combination With Ca-based P Binders in Patients With Hyperphosphatemia
This study consists of a 4 week run-in period with a Ca based phosphate binder and 12 weeks treatment period by MCI-196 or placebo, (both on Ca based phosphate binder).
- Conditions
- Chronic Kidney Disease, Dialysis, Hyperphosphatemia
- Trial name
- NCT00451295
- Testing
- MCI-196(colestilan(INN), Colestimide(JAN), CHOLEBINE®)
- Where
- 25 sites in Czechia, France and 8 more
- Volunteers
- 6 people
- Sponsor
- Tanabe Pharma Corporation
Chronic Kidney Diseases
Telemonitoring of Hypertensive Patients With Chronic Kidney Disease
Background: Hypertension, together with poorly controlled blood pressure (BP) are known risk factors for kidney disease and progression to kidney failure as well as increased cardiovascular (CV) morbidity and mortality.
- Trial name
- NCT04098354
- Testing
- home BP telemonitoring system .
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- University of Alberta
Kidney Diseases, Chronic Kidney Diseases
NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities
The overarching goal of this project is to refine and adapt previous work on the NAVIGATE-Kidney project for individuals with CKD.
- Trial name
- NAV-Kidney (NCT06810622)
- Testing
- Community health worker intervention, Standard Care (in control arm)
- Where
- 2 sites in United States
- Volunteers
- 448 people
- Sponsor
- University of Colorado, Denver
Contrast Induced Nephropathy
Oral Versus Intravenous Hydration to Prevent Contrast Induced Nephropathy
The increased risk for contrast-induced nephropathy (CIN) in patients with chronic kidney disease (CKD) undergoing coronary angiography (CAG) has been established.
- Trial name
- HYDRATE (NCT01093131)
- Testing
- Oral hydration, Oral sodium bicarbonate, Intravenous Hydration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Western Pennsylvania Hospital
Diabetes Mellitus, Type 2
A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease
The researchers are doing this study to see if semaglutide can slow down the growth and worsening of chronic kidney disease in people with type 2 diabetes.
- Trial name
- FLOW (NCT03819153)
- Testing
- Semaglutide
- Where
- 413 sites in United States, Argentina and 26 more
- Volunteers
- 3,533 people
- Sponsor
- Novo Nordisk A/S
Anemia, Chronic Kidney Disease
Efficacy and Safety of Peginesatide (AF37702) in the Treatment of Anemia in Participants With Chronic Kidney Disease
The purpose of this study is to evaluate the ability of peginesatide (AF37702) to increase and maintain increased hemoglobin levels in participants with chronic kidney disease (CKD) (either not on dialysis, receiving regular…
- Conditions
- Anemia, Chronic Kidney Disease, Chronic Renal Failure, Pure Red Cell Aplasia
- Trial name
- NCT00314795
- Testing
- Peginesatide
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 22 people
- Sponsor
- Takeda
Kidney Diseases, Metabolic Acidosis
Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5
The goal of this clinical trial is to learn about and test the effect of an acid/base diet, in chronic kidney patients with CKD stage 4 and 5 in an interventional study with a historical control.
- Conditions
- Kidney Diseases, Metabolic Acidosis, Renal Insufficiency, CKD
- Trial name
- REMA-CKD (NCT05970094)
- Testing
- Low PRAL
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Copenhagen
Chronic Kidney Disease stage4, Kidney Diseases
Medico-economic Impacts of NeLLY Service for Not on Dialysis Severe Chronic Kidney Disease
This medico-economic research project (PRME) aim to analyse NeLLY service efficiency for not on dialysis severe chronic kidney disease (DFG < 30ml/mn) patients care.
- Trial name
- NCT03348839
- Testing
- NeLLY service
- Where
- 10 sites in France
- Volunteers
- 600 people
- Sponsor
- Calydial
Lung Transplantation, Cystic Fibrosis
Predictive Value of PIIINP Urinary for the Development of Chronic Renal Failure in Patients With Cystic Fibrosis After Lung Transplantation (MUCO-IRC)
Chronic renal failure is a serious complication of lung transplantation especially in patients with cystic fibrosis. Their medical history prior to the Lung Transplantation has already exposed to kidney damage.
- Conditions
- Lung Transplantation, Cystic Fibrosis, Renal Failure
- Trial name
- MUCO-IRC (NCT01572194)
- Testing
- Urinary levels of PIIINP as a marker of changes in renal function
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Nantes University Hospital
Renal Disease
Investigation of the Effect of Intradialytic Exercise on Functional Capacity,Quality of Life in Hemodialysis Patients
Chronic renal failure (CKD) is defined as a chronic, progressive degeneration in the kidney's fluid-electrolyte balance and metabolic-endocrine functions as a result of the glomerular filtration rate (GFR) falling below 60…
- Trial name
- NCT05246956
- Testing
- Intradialytic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul Medipol University Hospital
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