Clinical trials: CKD - Chronic Kidney Disease
Hypertension, Diabetes Mellitus
Community Based Multiple Risk Factors Intervention Strategy
Randomized controlled trial of CORFIS Programme. The study objectives are as follows: 1. To determine the efficacy of a community based multiple risk factors interventional strategy (CORFIS) for a treatment period of 6 months in…
- Conditions
- Hypertension, Diabetes Mellitus, Hyperlipidemia
- Trial name
- CORFIS (NCT00490672)
- Testing
- No Active Intervention., Community Based Multiple Risk Factor Intervention Strategies
- Where
- 78 sites in Malaysia
- Volunteers
- 770 people
- Sponsor
- Ministry of Health, Malaysia
Brain Injuries, Malaria
An MRI Ancillary Study of a Malaria Fever Investigation
This study will seek consent from parents of children enrolled in the Malaria FEVER study to obtain neuroimaging and 12-month neuropsychiatric outcomes data and kidney function on their child.
- Conditions
- Brain Injuries, Malaria, MRI Imaging, Neurocognitive Deficits
- Trial name
- MRIA (NCT05746819)
- Testing
- Aggressive antipyretics therapy of fever vs usual care in the Malaria RCT study
- Where
- 2 sites in Malawi, Zambia
- Volunteers
- 181 people
- Sponsor
- University of Rochester
HIV
Does Micro-albuminuria is a Predictive Factor for Cognitive Impairment in Persons Living With HIV (PLHIV) Who Achieve cART-sustained Immunovirological Control ?
Chronic kidney disease (CKD), frequent in PLHIV, is a risk factor for cognitive impairment. Micro-albuminuria is an early manifestation of CKD and a marker of vascular risk, notably affecting the small vessels.
- Trial name
- ALCOVE (NCT02852772)
- Testing
- Cognitive function tests
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
End Stage Renal Disease, Anemia
Study of Roxadustat (FG-4592) in Participants With End-Stage Renal Disease Receiving Maintenance Hemodialysis
The primary objective of this study is to evaluate the efficacy and safety of roxadustat in participants with end-stage renal disease (ESRD) on maintenance hemodialysis (HD) therapy, previously treated with intravenous (IV)…
- Trial name
- NCT01147666
- Testing
- Roxadustat, Epoetin Alfa
- Where
- 25 sites in United States
- Volunteers
- 161 people
- Sponsor
- Kyntra Bio
Chronic Renal Disease
The Lighthouse Tenofovir Cohort Study
Lighthouse, in cooperation with the University Heidelberg Public Health Institute and the University Köln (Cologne) would like to set up a cohort to study baseline characteristics and long-term clinical outcomes of patients using…
- Trial name
- LighTen (NCT02381275)
- Testing
- Tenofovir Disoproxil Fumarate
- Where
- Malawi
- Volunteers
- 1,500 people
- Sponsor
- Lighthouse Trust
Heart Failure, Chronic Obstructive Pulmonary Disease (COPD)
Epidemiological Cluster Evaluation in Patients Admitted to Internal Medicine, With at Least One of the Following Diagnoses: Heart Failure, COPD, Renal Failure. The FADOI IN-CluDiMI Study
Improved medical care has led to an increase in both the age and clinical complexity of patients admitted to Internal Medicine wards, characterized by multiple chronic diseases.
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease (COPD), Chronic Kidney Disease (CKD)
- Trial name
- IN-CluDiMI (NCT07660757)
- Where
- Italy
- Volunteers
- 4,500 people
- Sponsor
- Fadoi Foundation, Italy
Chronic Kidney Disease
A Study to Learn More About How Safe Nurandociguat is and How it Affects the Way the Body Processes Rosuvastatin and Dabigatran in Healthy Adults
Researchers are looking for a better way to treat people who have chronic kidney disease. Chronic kidney disease (CKD) is a long-term condition where the kidneys do not work as well as they should.
- Trial name
- NCT07515339
- Testing
- Nurandociguat, Rosuvastatin, Dabigatran etexilate
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bayer
Chronic Kidney Disease
Senescence in Chronic Kidney Disease
The study goal is to assess the effect of senescent cell clearance on senescence burden, physical ability or frailty, and adipose tissue-derived mesenchymal stem cell (MSC) functionality in patients with chronic kidney disease…
- Trial name
- NCT02848131
- Testing
- Group 2: Dasatinib, Group 2: Quercetin
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Anemia
A Study of Mircera in Hemoglobin Control of Patients Transitioning to Dialysis.
This study will assess the efficacy and safety of methoxy polyethylene glycol-epoetin beta (Mircera) in the maintenance of hemoglobin levels in patients who have previously received treatment with epoetin alfa or darbepoetin…
- Trial name
- NCT00454246
- Testing
- methoxy polyethylene glycol-epoetin beta, epoetin alfa, darbepoetin alfa
- Where
- 78 sites in United States
- Volunteers
- 111 people
- Sponsor
- Hoffmann-La Roche
End Stage Renal Disease, Chronic Kidney Disease Requiring Chronic Dialysis
Pumpkin Seed Oil as a Nutraceutical for Hemodialysis Patients
Patients with end-stage renal disease (ESRD) on maintenance hemodialysis experience chronic systemic inflammation, oxidative stress, and dyslipidemia, which together drive much of the excess cardiovascular morbidity and mortality…
- Conditions
- End Stage Renal Disease, Chronic Kidney Disease Requiring Chronic Dialysis, Inflammation, Oxidative Stress
- Trial name
- NCT07710183
- Testing
- Pumpkin Seed Oil 1000 mg, Standard hemodialysis care
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Al-Mustansiriyah University
Xerostomia, Chronic Renal Failure
Effects of Photobiomodulation in Salivary Analysis of Chronic Renal Failure Patients
End-stage renal disease patients undergoing hemodialysis can present alteration in flow, concentrations and composition of saliva affecting oral health.
- Trial name
- NCT03647813
- Testing
- Photobiomodulation
- Volunteers
- 44 people
- Sponsor
- University of Nove de Julho
Diabetic Nephropathies
Low Energy Shockwave Therapy (LE-SWT): A Novel Treatment for Chronic Kidney Disease
The investigators aim to investigate whether low energy shockwave therapy (LE-SWT) can preserve kidney function in diabetic patients. Participants in this study will receive LE-SWT treatment 6 times over 3 weeks.
- Trial name
- NCT02515461
- Testing
- Low energy shockwave therapy
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
THROMBOSED AV GRAFTS
Pilot Study of IVUS Imaging During Endovascular Interventions of Failing Hemodialysis Access Grafts
This pilot study will provide data to aid in the planning of a follow-up multi-center randomized, controlled trial (RCT). As such, the sample size for this pilot is not driven by formal statistical hypothesis testing.
- Trial name
- NCT01929369
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Volcano Corporation
Chronic Kidney Diseases
Cerebrovascular Dysregulation in Chronic Kidney Disease
The purpose of this study is to test whether or not regular exercise training may improve brain blood flow regulation in patients with chronic kidney disease (CKD).
- Trial name
- NCT05571605
- Testing
- Exercise, Stretching
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of North Texas, Denton, TX
Chronic Kidney Disease Requiring Chronic Dialysis
Integrating BIA and eGFR for Nutritional Status in Hemodialysis Patients
This study looks at how measurements of body composition from Bioelectrical Impedance Analysis (BIA) and estimates of kidney function (eGFR) can be applied together to better assess the health of people on hemodialysis.
- Trial name
- NCT06873880
- Where
- Estonia
- Volunteers
- 30 people
- Sponsor
- University of Tartu
Chronic Kidney Disease (Stage 3-4)
Effect Of Education On Adherence, Self Care And Well-Being Of Patients With Chronic Kidney Disease
ABSTRACT Aim: The aim of the study was evaluate the effect of education provided to patients diagnosed with chronic kidney disease on adherence to illness, self-care, and well-being. Design: A randomised controlled trial.
- Trial name
- NCT07309861
- Testing
- Educational with chronic kidney disease
- Where
- Turkey (Türkiye)
- Volunteers
- 119 people
- Sponsor
- Trakya University
Chronic Kidney Disease, End Stage Kidney Disease
Reduction of Mortality Prior to and During the First 90 Days of Dialysis Through a Renal Rehabilitation Program
The mortality rate of treated patients with end stage renal disease(ESRD)is 22 deaths patient-years at risk in 2006. Incident patients with ESRD are most vulnerable within the first 90 days of dialysis, with an annualized…
- Conditions
- Chronic Kidney Disease, End Stage Kidney Disease, Cardiovascular Disease
- Trial name
- NCT00792454
- Testing
- exercise training
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- MaineHealth
Chronic Kidney Disease
An Observational Study to Learn More How Chronic Kidney Disease Gradually Changes Over Time in Adults Using Electronic Healthcare Records (CKD Natural History Study)
This is an observational study in which the health data of people with chronic kidney disease are studied using electronic healthcare records.
- Trial name
- CKD-NH (NCT05914259)
- Testing
- No Intervention
- Where
- Germany
- Volunteers
- 969,394 people
- Sponsor
- Bayer
Diabetes
Clinical Characteristics and Disease Burden of Diabetic Patients Based on Tianjin Regional Database
The study aims to investigate the clinical characteristics, treatment, and economic burden of disease of Chinese diabetic/non-diabetic patients with/without established cardiovascular disease (CVD), chronic kidney disease (CKD)…
- Trial name
- NCT04903496
- Where
- China
- Volunteers
- 1,233,162 people
- Sponsor
- Boehringer Ingelheim
Hyperphosphatemia, End Stage Renal Disease
Ferric Citrate for the Treatment of Hyperphosphatemia in Patients With Chronic Kidney Disease Undergoing Hemodialysis
To evaluate the efficacy and safety of ferric citrate tablet in the control of serum phosphorus levels in patients with chronic kidney disease undergoing hemodialysis.
- Conditions
- Hyperphosphatemia, End Stage Renal Disease, ESRD
- Trial name
- NCT04456803
- Testing
- Ferric citrate tablet, Sevelamer carbonate tablet
- Where
- 20 sites in China
- Volunteers
- 239 people
- Sponsor
- Sinomune Pharmaceutical Co., Ltd
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