Clinical trials: CKD on Hemodialysis Patients
CKD (Chronic Kidney Disease) Stage 5D, Hemodialysis
Effect of Kidney Replacement Therapy with Polymethylmethacrylate Membranes on Pruritus-related Quality of Life in Patients Receiving Maintenance Haemodialysis
This randomized controlled trial aims to evaluate the effect of polymethylmethacrylate dialysis membranes use on the intensity of pruritus in patients with CKD stage 5D receiving maintenance hemodialysis.
- Conditions
- CKD (Chronic Kidney Disease) Stage 5D, Hemodialysis, Pruritis
- Trial name
- NCT06671535
- Testing
- Polymethylmethacrylate membrane, polysulfone membranes
- Where
- Russia
- Volunteers
- 62 people
- Sponsor
- Saint Petersburg State University, Russia
End-stage Kidney Disease
Symptom Management in Patients on Dialysis
This is a parallel arm, pilot study used to examine the feasibility of electronic patient reported outcome measures (ePROMs) for symptom assessment and monitoring as well as a linked self-management support and decision support…
- Trial name
- NCT05515991
- Testing
- SUPPORT-DIALYSIS with Access to Output Report and Information Hub, SUPPORT-DIALYSIS Only
- Where
- 2 sites in Canada
- Volunteers
- 36 people
- Sponsor
- University Health Network, Toronto
Anemia, Kidney Failure, Chronic
A Phase 2 Study of Intravenous or Subcutaneous Dosing of Sotatercept (ACE-011) in Patients With End-Stage Kidney Disease on Hemodialysis
To determine the optimal route of administration, dose level, and safety of intravenous and subcutaneous dosing of sotatercept for maintaining hemoglobin levels in subjects who are on hemodialysis.
- Trial name
- NCT01999582
- Testing
- Sotatercept
- Where
- 23 sites in Belgium, Germany and 3 more
- Volunteers
- 50 people
- Sponsor
- Celgene
Chronic Renal Failure, Sleep Disorder
Light Therapy on Sleep Quality in Dialysis Patients
Sleep disorders are common in dialysis patients. At present, the management of insomnia in patients with chronic renal failure is not significantly different from that of the general population, which focuses on the management of…
- Conditions
- Chronic Renal Failure, Sleep Disorder, Hemodialysis, Light Therapy
- Trial name
- LUMIDIAL (NCT04089397)
- Testing
- Light Therapy
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Atrial Fibrillation, Heart Diseases
Left Atrial Appendage Occlusion With WATCHMAN® Device in Patients With Non-valvular Atrial Fibrillation and End-stage Chronic Kidney Disease on Hemodialysis
Atrial fibrillation (AF) is more common in patients with renal disease compared to the general population an risk increase to as much as 10 times in patients on hemodialysis (HD).
- Conditions
- Atrial Fibrillation, Heart Diseases, Renal Disease, Bleeding
- Trial name
- WATCH-HD (NCT03446794)
- Testing
- Non Intervention
- Where
- 20 sites in Spain
- Volunteers
- 300 people
- Sponsor
- Fundación EPIC
Hemodialysis, Endothelial Dysfunction
Impact of Garlic on the Clinical Outcome in Chronic Hemodialysis Patients
Chronic kidney disease (CKD) is an irreversible condition marked by reduced kidney function or structural abnormalities lasting over three months, affecting a significant portion of the global population.
- Conditions
- Hemodialysis, Endothelial Dysfunction, CKD, Inflammation
- Trial name
- NCT07461012
- Testing
- Dried garlic powder (Garlic extract) - Allium sativum.
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Ain Shams University
Chronic Kidney Diseases, Hemodialysis Complication
Clinical Outcomes of Hemodialysis in Brazil (COHEBRA): a Prospective Cohort Study
Introduction: Chronic kidney disease (CKD) is characterized by progressive decrease in glomerular filtration rate (GFR), eventually reaching the end-stage renal disease (ESRD) requiring renal replacement therapy (RRT).
- Trial name
- COHEBRA (NCT05273424)
- Where
- Brazil
- Volunteers
- 500 people
- Sponsor
- Catholic University of Pelotas
Chronic Kidney Disease Stage 5 on Dialysis
Inspiratory Muscle Training for Chronic Kidney Disease Patients on Hemodialysis
Chronic Kidney Disease (CKD) is a global public health problem with an increasing prevalence and incidence, poor prognosis, and high costs.
- Trial name
- NCT05241652
- Testing
- Inspiratory Muscle Training with an intensity of 50% MIP, Inspiratory Muscle Training with an intensity of 10% MIP
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Padjadjaran
Chronic Kidney Disease, Hemodialysis
Resistant Starch Supplementation Effects on the Intestinal Tract Profile and Cardiovascular Markers in Renal Patients
The objective of this study is to assess whether supplementation with resistant starch from the rice-flour coffee developed by EMBRAPA, as well as from an already industrialized product (Hi-Maize of Ingredion®) could modulate the…
- Conditions
- Chronic Kidney Disease, Hemodialysis, Non-dialysis Patients
- Trial name
- Starch (NCT02706808)
- Testing
- 'resistance starch for CKD
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Kidney Disease, Kidney Failure
Hemodialysis in the Elderly (70yrs & Older)
This will be a prospective, single institution, parallel-group, single-blinded, randomized-controlled, two-arm, effectiveness study comparing autologous arteriovenous fistula versus hemodialysis access grafts in the elderly.
- Conditions
- Kidney Disease, Kidney Failure, Chronic Kidney Disease
- Trial name
- ELDERLY (NCT03065972)
- Testing
- Surgical fistula creation from patient's anatomy, Surgical Graft implant
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- E. Peden, MD
End Stage Renal Disease, Chronic Kidney Disease Stage 5
Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis
The purpose of this study is to determine if the study drug is safe, tolerable and active in reducing fluid overload/weight gain between dialysis sessions for patients with End Stage Renal Disease on Hemodialysis.
- Conditions
- End Stage Renal Disease, Chronic Kidney Disease Stage 5, ESRD
- Trial name
- NCT01764854
- Testing
- AZD1722 (in-patient), AZD1722 (out-patient)
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Ardelyx
Chronic Kidney Disease
Impact of Presurgical Exercise on Hemodialysis Fistula Outcomes
The purpose of this research study is to determine whether two different types of forearm exercise, performed before fistula creation surgery, can improve surgery success and fistula maturation.
- Trial name
- NCT02205944
- Testing
- Progressive Handgrip Exercise
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- University Health Network, Toronto
Iron Deficiency Anemia Treatment, Chronic Kidney Disease(CKD)
Compare Efficacy/Safety of Repeat Doses of Ferumoxytol With Iron Sucrose in CKD Subjects With IDA and on Hemodialysis
The objectives of this study are to compare the efficacy and safety of repeat doses of intravenous (IV) ferumoxytol with IV iron sucrose for the treatment of IDA in subjects with hemodialysis-dependent CKD.
- Trial name
- NCT01227616
- Testing
- Ferumoxytol, Iron Sucrose
- Where
- 43 sites in United States, Canada and 1 more
- Volunteers
- 296 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Kidney Failure, Chronic, Dietary Modification
Dietary Sodium-Restriction (DIS) and Renal Meals (RM) for Hemodialysis (HD)(DISaRM-HD)
Chronic volume overload (VO) is a primary factor responsible for the excessive cardiovascular morbidity and mortality in hemodialysis (HD) patients.
- Trial name
- DISaRM-HD (NCT04991441)
- Testing
- Controlled Dietary Sodium Restriction, Control Diet & Controlled Dietary Sodium Restriction
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Illinois at Urbana-Champaign
Secondary Hyperparathyroidism (SHPT) in Subjects With Chronic Kidney Disease (CKD) on Hemodialysis
Investigating the Safety and Efficacy of SHR6508 Injection in the Treatment of Secondary Hyperparathyroidism in Hemodialysis Patients : A Multicenter, Long-term Clinical Trial
This is a multicenter, single-arm, long-term safety and tolerability trial. A total of 300 subjects with chronic kidney disease on hemodialysis are planned to be enrolled.
- Trial name
- NCT06236295
- Testing
- SHR6508
- Where
- China
- Volunteers
- 303 people
- Sponsor
- Shanghai Hengrui Pharmaceutical Co., Ltd.
Kidney Diseases
Conversion From Standard Phosphate Binder Therapy to Fosrenol® (Lanthanum Carbonate) in Chronic Kidney Disease Stage 5
The main aim of this research study is to see if giving Fosrenol®, a chewable tablet, to patients on haemodialysis works as well as other treatments currently used to lower blood phosphorus levels.
- Trial name
- NCT00452478
- Testing
- Lanthanum carbonate
- Where
- 14 sites in Austria, Belgium and 4 more
- Volunteers
- 68 people
- Sponsor
- Shire
Coronary Calcification
Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients
Until 2013 the reported incidence of chronic kidney disease varied widely between countries, reporting the highest prevalence Taiwan, the region of Jalisco in Mexico and United States, with 458, 421 and 363 individuals per…
- Trial name
- NCT04247087
- Testing
- phytomenadione
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Mexicano del Seguro Social
Hyperparathyroidism, Secondary, Kidney Failure, Chronic
Hyperparathyroidism and Dialysis Adequacy in Hemodialysis Patients
This cross-sectional study aims to determine the prevalence of secondary hyperparathyroidism among end-stage renal disease patients on regular hemodialysis and to evaluate its relationship with dialysis adequacy at Assiut…
- Conditions
- Hyperparathyroidism, Secondary, Kidney Failure, Chronic, Chronic Kidney Diseases
- Trial name
- NCT07820150
- Volunteers
- 130 people
- Sponsor
- Assiut University
Renal Osteodystrophy
12-month Study of AMG 073 in Renal Osteodystrophy
4 doses of AMG 073 or placebo over 52 weeks after a 30-day screening period. Throughout the study, labs will be drawn to measure analytes such as iPTH and corrected calcium.
- Trial name
- NCT00527085
- Testing
- AMG 073
- Volunteers
- 45 people
- Sponsor
- Amgen
Chronic Kidney Disease on Hemodialysis
Experience of Young Adult Kidney Patients Requiring Haemodialysis
This study has been designed with individuals with lived experience of kidney disease and is a mixed methods study. The aim is to explore experiences of young adults (16-30) receiving haemodialysis in a centre or in a hospital…
- Trial name
- YAoHD (NCT07494695)
- Where
- United Kingdom
- Volunteers
- 92 people
- Sponsor
- University of Hertfordshire