Clinical trials: CLBP - Chronic Low Back Pain
Low Back Pain
Comparing Yoga Nidra, Yoga, and Control Condition on Pain in Individuals With Chronic Low Back Pain
Individuals with chronic low back pain will undergo a yoga, yoga nidra, and control condition on separate visits. Each visit, before and after the intervention, participants with rate their pain in response to heat stimuli, a sit…
- Trial name
- NCT07543835
- Testing
- Yoga, Yoga Nidra, Control Condition
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Central Florida
Chronic Low-back Pain
Persica 002 Phase 1b PP353 vs Placebo in the Treatment of Low Back Pain
A Phase 1b study to investigate the efficacy of PP353 compared to placebo in the treatment of chronic low back pain associated with bone oedema.
- Trial name
- NCT04238676
- Testing
- PP353
- Where
- 10 sites in Denmark, New Zealand and 2 more
- Volunteers
- 43 people
- Sponsor
- Persica Pharmaceuticals Ltd
Low Back Pain
Traditional Acupuncture and Myofascial Trigger Point Dry Needling and Acupressure for Chronic Low Back Pain
The purpose of this study is to compare the therapeutic effects of acupuncture using traditional acupoints and Ashi points with myofascial trigger points superficial dry needling and acupressure, followed by postisometric…
- Trial name
- NCT00804089
- Testing
- Traditional needle acupuncture, Myofascial trigger point dry needling, Myofascial trigger point acupressure
- Where
- 2 sites in Ecuador
- Volunteers
- 90 people
- Sponsor
- Hermano Miguel Foundation
Low Back Pain, Chronic Pain
The Effects of Dance Therapy in Women With Chronic Low Back Pain
The aim of this study is to investigate the effect of dance therapy on balance, falling, body awareness and functionality parameters in patients with chronic low back pain.
- Conditions
- Low Back Pain, Chronic Pain, Chronic Low-back Pain
- Trial name
- NCT05301491
- Testing
- Dance Therapy Group, Exercise Group, Pyhsiotherapy Modalities
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Chronic Low Back Pain (CLBP)
Assessment of Different Clinical Techniques to Treat Patients With Chronic Low Back Pain
This clinical trial aims to assess the effectiveness of different clinical techniques in treating patients with chronic low back pain (CLBP).
- Trial name
- CLBP (NCT06453291)
- Testing
- NSAIDs (Nonsteroidal Anti-Inflammatory Drugs):, Standard Physical Therapy, Neuromodulation via Dorsal Root Ganglion (DRG):
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Iffat Anwar Medical Complex
Post-Dural Puncture Headache, Chronic Headache
Long Term Outcomes After Accidental Dural Puncture ADP Study
Post Dural Puncture Headache (PDPH) causes significant short-term disability, prevents mobilisation, affects childcare activities and results in prolonged hospital stay.
- Conditions
- Post-Dural Puncture Headache, Chronic Headache, Chronic Low Back Pain
- Trial name
- NCT03080779
- Where
- 3 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- University Hospitals, Leicester
Chronic Low Back Pain
Pulsed Shortwave Therapy Treatment for Chronic Musculoskeletal Low Back Pain
The ActiPatch is a cutaneous device which is CE marked approved for relief of pain and has FDA clearance as an over the counter device for the adjunctive treatment of osteoarthritis of the knee and plantar fasciitis.
- Trial name
- PSWT (NCT03240146)
- Testing
- Pulsed Shortwave Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- BioElectronics Corporation
Low Back Pain, Amputation
The Association Between Amputation Level and Chronic Low Back Pain After Combat-Related Amputation
Patients with combat-related lower limb amputations frequently experience chronic low back pain during long-term rehabilitation and prosthetic use.
- Trial name
- LEVEL-BACK (NCT07626294)
- Where
- Ukraine
- Volunteers
- 300 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Chronic Low Back Pain
Laser and Therapeutic Ultrasound in the Management of the Chronic Non-specific Low Back Pain
The objective of this study is evaluate the laser and ultrasound effect on pain and disability in women with non-specific chronic low back pain.
- Trial name
- NCT02150096
- Testing
- continuous ultrasound group, pulsed ultrasound group, low level laser therapy group
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Low Back Pain
Assessment of LTP-like Pain Amplification in Chronic Low Back Pain Patients
The present study is aimed to assess the LTP-like pain amplification in chronic low back pain patients to explore the central and peripheral effect for pain LTP.
- Trial name
- NCT03362827
- Testing
- Chronic low back pain patients, Subjects without chronic low back pain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Chronic Pain, PERIPHERAL NEUROPATHY
Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.
- Conditions
- Chronic Pain, PERIPHERAL NEUROPATHY, Occipital Neuralgia, Chronic Hip Pain
- Trial name
- NCT07639060
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Chronic Non-Specific Low Back Pain
Dynamic Versus Traditional Core Strengthening Exercises in Patients With Chronic Non-specific Low Back Pain
This research investigated the effectiveness of two different types of core strengthening exercises: dynamic versus traditional exercises.
- Trial name
- CNLBP (NCT07884396)
- Testing
- Routine Physiotherapy, Dynamic Core Strengthening Exercises, Traditional Core Strengthening Exercises
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- University of Lahore
Chronic Low Back Pain
Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)
The primary purpose of the study was to test the efficacy of 2 tablets (twice daily) of ABT-712, compared to placebo, administered over a 4-week period in participants with moderate to severe mechanical chronic low back pain…
- Trial name
- NCT00761150
- Testing
- ABT-712
- Where
- 32 sites in United States
- Volunteers
- 308 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Low Back Pain
Effects of Kinesio Tape on Chronic Low Back Pain
This clinical trial aims to examine kinesiotape's (KT) short-term effect on individuals with nonspecific chronic LBP (CLBP), including back-specific body perception, pain, functional disability, and physical activity.
- Trial name
- NCT05866159
- Testing
- Kinesiotape using Rocktape®
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
Chronic Low Back Pain
VRFR- Immersive Virtual Reality Use in a Spine Functional Restoration Program - A Feasibility Study
This clinical trial investigates the feasibility of integrating immersive virtual reality (VR) technology into a functional restoration program (FRP) for patients with chronic low back pain (CLBP).
- Trial name
- VRFR (NCT06724679)
- Testing
- Utilisability of an immersive VR device in a functional restoration program (FRP) for patients with chronic low back pain.
- Where
- 5 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Chronic Low Back Pain, Facet Joint Syndrome
MRgFUS and RFA for Treatment of Facet-joint Osteoarthritis Low Back Pain
This is a prospective, randomized, two-arm, phase II study. The purpose of this study is: To evaluate and compare the efficacy and safety of magnetic resonance-guided focused ultrasound (MRgFUS) and radiofrequency ablation (RFA)…
- Trial name
- NCT03168802
- Testing
- MRgFUS ablation, Radiofrequency ablation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Medical University Hospital
Chronic Low-back Pain (cLBP)
Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain
Chronic low back pain (CLBP) is a major health challenge in Canada, leading to substantial disability and socioeconomic burden, particularly among Veterans. In military Veterans, LBP is the most common chronic pain condition.
- Trial name
- NCT06999772
- Testing
- Active rTMS, Psychologically-informed physiotherapy (PiP), Usual physiotherapy
- Where
- 2 sites in Canada
- Volunteers
- 96 people
- Sponsor
- Laval University
Low Back Pain
Assessment of Activities of Daily Living in Adults With Chronic Low Back Pain Using a Nonoperative Treatment Modality
The investigators hypothesize that treatment with non-invasive spinal decompression reduces discogenic low back pain (LBP), decreases visual analog pain scale scores, increases activities of daily living and decreases medication…
- Trial name
- NCT02729181
- Testing
- DRX9000
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Integrity Life Sciences
Low Back Pain
Long Term Safety and Efficacy Study of Tanezumab in Japanese Adult Subjects With Chronic Low Back Pain
This study will investigate the long-term safety and efficacy of a fixed dose of tanezumab 5 mg and 10 mg administered subcutaneously (SC) seven times at 8 week intervals.
- Trial name
- TANGO (NCT02725411)
- Testing
- Celecoxib, Tanezumab 5 mg, Tanezumab 10 mg
- Where
- 55 sites in Japan
- Volunteers
- 277 people
- Sponsor
- Pfizer
Low Back Pain, Pain
D-cycloserine in the Management of Chronic Low Back Pain
Pre-clinical studies in rats suggest that D-cycloserine (DCS) is effective in the management of chronic neuropathic pain. This pilot study will attempt to determine the effect of D-cycloserine in the treatment of chronic low back…
- Trial name
- NCT00125528
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Thomas J. Schnitzer