Clinical trials: CMC Arthritis
Arthritis Wrist
Orthotic Management of CMC Osteoarthritis
This study will investigate the effectiveness of 3D printed splints for the treatment of thumb osteoarthritis (CMC OA). Currently, these splints are made by Occupational Therapists and Physical Therapists out of low temperature…
- Trial name
- NCT04297943
- Testing
- Orthosis fabrication, Thermal Sensor Monitoring of Orthosis Use, 4D CT Scan
- Volunteers
- 68 people
- Sponsor
- Western University, Canada
CMC Arthritis
Thumb Metacarpophalangeal Hyperextension in an Arthritic Population; Part 2
This is the second phase of a clinical study to assess MP hyperextension in CMC arthritis. In the first phase, submitted for publication, the investigators demonstrated that there is poor correlation between dynamic control of…
- Trial name
- NCT05835830
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana Hand to Shoulder Center
CMC Joint Arthritis
Thumb Hemi-Arthroplasty With Natural Kinematics; a Prospective Multicenter Study to Confirm the Safety and Efficacy of the InDx Implant
Prospective, multicentric non-comparative confirmatory study to evaluate the safety and performance of the InDx CMC implant for the treatment of CMC joint arthritis.
- Trial name
- THANKS PRO (NCT06467760)
- Testing
- InDx CMC Implant
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 14 people
- Sponsor
- Loci Orthopaedics
Arthritis of Carpometacarpal Joint of Left Thumb, Arthritis of Carpometacarpal Joint of Right Thumb
Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis
The goal of this clinical trial is to learn about the use of turmeric (Curcumin) as a treatment for pain of thumb-joint arthritis. Turmeric is commonly being used as an over-the-counter treatment for musculoskeletal pain.
- Trial name
- NCT06359665
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brent DeGeorge
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Use of FlexHD as Post Trapeziectomy Spacer
The objective of this study is to show that using FlexHD® (or HADM) to fill the empty space created by removal of the trapezium improves the subject's outcome and subsequent functionality of the basilar joint arthroplasty…
- Trial name
- MTF (NCT01998594)
- Testing
- Arthroplasty
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Osteoarthritis
Ligament Reconstruction in an Accelerated Rehabilitation Protocol
The investigators have found that their patients who get earlier rehabilitation following ligament reconstruction and tendon interposition (LRTI) surgery with interference screws have experienced better outcomes.
- Trial name
- NCT05571241
- Testing
- Fast rehabilitation program
- Where
- Canada
- Sponsor
- Dr. David Pichora
Carpometacarpal (CMC) Joint Arthritis
Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting
The oval-8 splint has been developed for many uses in finger pathology and trauma. It has not, however, been used to treat thumb carpometacarpal (CMC) joint arthritis.
- Trial name
- Oval-8 (NCT02266095)
- Testing
- Oval-8 Splint, Tee Pee Splint, Forearm Based Splint
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Osteoarthritis
Double-Blind,Randomized,Placebo-Controlled Efficacy & Safety Study of EUFLEXXA™ for Treatment of OA of the First CMC
This multicenter, double-blind, randomized, parallel-group, active-controlled trial will be performed in approximately 80 subjects with chronic idiopathic osteoarthritis (OA) of the first carpo-metacarpal joint (CMC).
- Trial name
- NCT00423371
- Testing
- sodium hyaluronate
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Ferring Pharmaceuticals
Osteoarthritis
Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)
This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the first CMC joint in the hand compared to LRTI.
- Trial name
- GRIP 2 (NCT03247439)
- Testing
- Cartiva
- Where
- 9 sites in United States, United Kingdom
- Volunteers
- 74 people
- Sponsor
- Cartiva, Inc.
Osteoarthritis
Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis
This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the CMC joint in the hand.
- Trial name
- GRIP (NCT02391506)
- Testing
- Cartiva
- Where
- 9 sites in Canada, United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cartiva, Inc.
Thumb Osteoarthritis
Artificial Intelligence in Trapeziometacarpal Joint Osteoarthritis: Improving Assessment and Clinical Decision-Making
This is a retrospective cohort study utilizing radiographic and computed tomography (CT) imaging data collected during routine clinical care at Schulthess Klinik Zürich.
- Trial name
- TMCAI (NCT07148349)
- Testing
- No Intervention: Observational Cohort
- Where
- Switzerland
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Arthritis, Thumb Osteoarthritis
Thumb Basal Joint (CMC I) Arthritis - Preoperative Anxiety/Depression, Outcome Instruments, Carpal Cinematics and Cost-utility
A project aiming to promote evidence based practice when treating thumb basal joint (CMC I) arthritis. We will aim to: 1) provide the minimal clinical difference of two general outcome instruments, 2) evaluate the association…
- Conditions
- Arthritis, Thumb Osteoarthritis, Arthropathy, Quality of Life
- Trial name
- NCT04826380
- Testing
- Trapeziectomy
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- Töölö Hospital
Carpometacarpal (CMC) Joint Arthritis
Mini TightRope Suspensionplasty Versus Ligament Reconstruction and Tendon Interposition for Thumb Carpometacarpal Osteoarthritis
Thumb carpometacarpal osteoarthritis is a common cause of pain, weakness and functional disability. Trapeziectomy with ligament reconstruction and tendon interposition (LRTI) is considered a standard surgical procedure, whereas…
- Trial name
- NCT07698301
- Testing
- Mini tightrope suspensionplasty, Ligament Reconstruction and Tendon Interposition (LRTI)
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Theodoros Mylonas
Pain, Osteoarthritis
Psychosocial Factors a Prognostic Study of Pain in Patients With CMC Osteoarthritis
In this clinical trial, females with a diagnosis of thumb CMC OA, will be recruited. The primary outcome of potential risk factors of osteoarthritis, pain and function will be measured using the demographic data, visual analog…
- Trial name
- CMC (NCT03821298)
- Testing
- Standard of Care Hand Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gannon University