Clinical trials: CONTROL Condition
Heart Failure
A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy
This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure.
- Trial name
- 8282-Reduced (NCT06979375)
- Testing
- CDR132L
- Where
- 92 sites in Australia, Czechia and 8 more
- Volunteers
- 200 people
- Sponsor
- Novo Nordisk A/S
Opioid Use Disorder
KIOS Mobile App Evaluation
Evaluation of a mobile medical app (KIOS) vs. treatment as usual for the treatment of opioid use disorder (OUD).
- Trial name
- NCT06212557
- Testing
- KIOS App, KIOS App education, Treatment as usual
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
COVID-19 Pneumonia, Virus Diseases
Investigation of Efficacy and Safety of Electrical Signal Therapy Provided by Dr Biolyse® Device in COVID-19 Disease
Dr. Biolyse® is a device with artificial intelligence that works in sync with the immune system and can be integrated like an element of this system. It is designed to develop chemical immunity within the body against infections.
- Conditions
- COVID-19 Pneumonia, Virus Diseases, COVID-19
- Trial name
- DoBiC-19 (NCT06113757)
- Testing
- Signal Therapy provided by Dr.Biolyse device, Liquid Support Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- AVB Biotechnology
Knee Osteoarthritis
Therapeutic Effects of Insoles on Patients With Knee Osteoarthritis
Using double blind, randomized controlled design to study the immediate, short-term and intermediate-term therapeutic effects of ready-made full-length lateral wedged shoe insoles and customized full-length lateral wedged shoe…
- Trial name
- NCT01765101
- Testing
- customized insoles, ready made insoles
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Pathological Gambling
Deep Low-Frequency Repetitive Transcranial Magnetic Stimulation for Cessation of Pathological Gambling
Pathological gambling (PG) is characterized by a persistent pattern of continued gambling behavior despite its adverse consequences.
- Trial name
- NCT01154712
- Testing
- Real Deep TMS
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- BeerYaakov Mental Health Center
Migraine Headache
Cupping and Serkangabin Versus Conventional Migraine Treatment
Migraine is the most common recurrent headache. Current therapy of migraine headache consists of multiple drug groups for control of attack and prophylaxis against recurrent attacks.
- Trial name
- NCT01476930
- Testing
- cupping and serkangabin syrup, conventional migraine drug treatment
- Where
- Iran
- Volunteers
- 391 people
- Sponsor
- Birjand University of Medical Sciences
Heart Failure, Congestive, Heart Decompensation
A Study of Two Doses of Intravenous NATRECOR hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest
The purpose of this study is to assess the safety and efficacy of two doses of intravenous NATRECOR® hBNP (a recombinant form of the natural human peptide normally secreted by the heart) versus placebo in the treatment of…
- Trial name
- NCT00288730
- Testing
- nesiritide
- Volunteers
- 127 people
- Sponsor
- Scios, Inc.
Virtual Reality, Anxiety
The Effect of Virtual Reality Application on Anxiety and Patient Satisfaction During Intrauterine Insemination (IUI)
This study will conduct as a randomized pretest-posttest study to examine the effect of virtual reality glasses (VRG) application during the IUI procedure on anxiety and patient satisfaction.
- Conditions
- Virtual Reality, Anxiety, Patient Satisfaction, Intrauterine Insemination (IUI)
- Trial name
- (IUI) (NCT06346730)
- Testing
- Virtual reality glasses to intervention group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Systemic Lupus Erythematosus
PRV-3279-2a Trial in Systemic Lupus
The PREVAIL-2 study was designed to assess the safety and potential efficacy of PRV-3279 in flare prevention in systemic lupus erythematosus (SLE) participants with active disease after amelioration induced by corticosteroid…
- Trial name
- PREVAIL-2 (NCT05087628)
- Testing
- PRV-3279
- Where
- 36 sites in United States, China and 2 more
- Volunteers
- 28 people
- Sponsor
- Provention Bio, a Sanofi Company
Healthy Aging, Overweight and Obesity
Multi-Domain Exercise Program In Older Women
The goal of this clinical trial is to learn whether a long-term exercise program can improve physical health and well-being in older women aged 60 years and older who live in the community.
- Conditions
- Healthy Aging, Overweight and Obesity, Physical Fitness, Psychological Well-being
- Trial name
- MD-EX Women (NCT07311265)
- Testing
- Supervised Multidomain Exercise Program
- Where
- Brazil
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Universidade do Oeste de Santa Catarina
Osteoarthritis, Hip, Osteonecrosis
Effect of Cycle Ergometer in the Rehabilitation of Elderly Patients With Total Hip Arthroplasty
The aim of this study is to evaluate the effects of an exercise program with a cycle ergometer in functional outcome and related-health quality of life (RHQL) in elderly patients with total hip arthroplasty.
- Trial name
- NCT01622465
- Testing
- Ergometer cycling, Conventional exercises
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- University of Campinas, Brazil
Covid19
A Phase 2 Clinical Trial of MW33 Injection in Patients With COVID-19
This study is designed as a multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the clinical efficacy and safety of MW33 injection in patients with mild or moderate COVID-19, and to evaluate its…
- Trial name
- NCT04627584
- Testing
- MW33 injection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Mabwell (Shanghai) Bioscience Co., Ltd.
Stroke, Equinus Deformity
Extracorporeal Shock Wave Therapy on Spastic Equinus Foot in Stroke Patients
The goal of this study is to evaluate long term effects of focused extracorporeal shock wave therapy (fESWT) on triceps surae spasticity in stroke patients according to the number of sessions applied.
- Conditions
- Stroke, Equinus Deformity, Spasticity, Muscle
- Trial name
- NCT06547684
- Testing
- fESWT
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Teresa Mateu Campos
Pneumoconiosis
Evaluating the Efficacy and Safety of Modified Qing-Zao-Jiu-Fei Decoction on Pneumoconiosis Patients
This is a multicenter, randomized, double-blind, placebo-controlled study to investigate the beneficial efficacy and safety of Chinese medicine formula Modified Qing Zao Jiu Fei Decoction (MQZJFD) on pneumoconiosis patients.
- Trial name
- NCT07178184
- Testing
- Modified Qing-Zao-Jiu-Fei Decoction (MQZJFD)
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Pancreatic Ductal Carcinoma
A Study of PEGylated Recombinant Human Hyaluronidase in Combination With Nab-Paclitaxel Plus Gemcitabine Compared With Placebo Plus Nab-Paclitaxel and Gemcitabine in Participants With Hyaluronan-High Stage IV Previously Untreated Pancreatic Ductal Adenocarcinoma
The purpose of this study is to compare the efficacy and safety of PEGylated Recombinant Human Hyaluronidase (PEGPH20) combined with nab-paclitaxel plus gemcitabine (PAG treatment), compared with placebo combined with…
- Trial name
- NCT02715804
- Testing
- Biological: PEGylated Recombinant Human Hyaluronidase (PEGPH20), nab-Paclitaxel, Gemcitabine
- Where
- 217 sites in United States, Australia and 20 more
- Volunteers
- 492 people
- Sponsor
- Halozyme Therapeutics
Postcraniotomy Headache, Intraoperative Analgesic Use
Diclofenac Administered Before Skull Operations Reduces the Severity of Headache After the Intervention
Purpose: According to the proposal of the International Headache Society acute postcraniotomy headache (PCH) is defined as a headache of variable intensity, being most serious at the site of surgical intervention and developing…
- Conditions
- Postcraniotomy Headache, Intraoperative Analgesic Use, Postoperative Analgesic Use, Postoperative Complications
- Trial name
- NCT01907984
- Testing
- Diclofenac, Midazolam
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- University of Debrecen
Elderly (People Aged 65 or More)
Efficacy of an Animated Video-Guided Exercise Intervention in Older Adults
Impaired mobility in older adults significantly exacerbates the risk of falls and subsequent injuries. Beyond physical sequelae, fall precipitate psychological burdens, notably the fear of falling and kinesiophobia.
- Trial name
- NCT07707752
- Testing
- an animation-guided- exercise training program, home based exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mustafa Kemal University
Alzheimer's Disease
Zydena on Cognitive Function of Alzheimer's Disease Patients
The purpose of this study is to determine whether Zydena (Udenafil) has positive effect on cognitive function in patients with Alzheimer's disease. This study is a randomized, double blind, placebo-controlled multicenter study.
- Trial name
- NCT01940952
- Testing
- Zydena (Udenafil) 50mg + Donepezil 5mg or 10mg, Zydena (Udenafil) 100mg + Donepezil 5mg or 10mg
- Where
- South Korea
- Volunteers
- 210 people
- Sponsor
- Samsung Medical Center
Diverticulosis, Colonic
Mechanistic Randomized Controlled Trial (RCT) of Mesalazine in Symptomatic Diverticular Disease
Diverticulosis (bulges in the bowel wall) affects two third of the elderly population in the UK. Diverticular disease and its complications are responsible for 68000 hospital admissions and 2000 deaths per year.
- Trial name
- NCT00663247
- Testing
- Mesalazine
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
Gingival Recession, Localized
Effectiveness of Micro Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects
The objective of this project is to evaluate 1-year outcomes of treatment of MAGRD using a modified coronally advanced tunnel technique (MCAT) with either conventional CTG (control group) or micro-CTG (test group).
- Trial name
- NCT06030947
- Testing
- Coronally Advanced Flap combined with a Connective Tissue Graft, Coronally Advanced Flap combined with micro Connective Tissue Graft, Division of the Connective Tissue Graft into multiple micro Connective Tissue Grafts
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Göteborg University
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