Clinical trials: CONTROL Condition
Diabetes Mellitus, Type 2, Non-alcoholic Fatty Liver Disease
Efficacy Study of Diacerein on Glycemic Control and Liver Fat in Type 2 Diabetes Subjects
This study is conducted to test the hypothesis that in uncontrolled type 2 diabetic adults treatment with diacerein will improve glycemic control and will reduce liver fat within a 24 month period.
- Trial name
- DGCLFT2DM (NCT02242149)
- Testing
- Diacerein
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Self-Compassion, Physical Inactivity
A Single-arm Pilot and Feasibility Study of the CALM Hearts Intervention
The primary aims of this study are to explore the feasibility, acceptability, and safety, of the Compassionate And Loving Mindset towards heart health risk (CALM Hearts) intervention.
- Conditions
- Self-Compassion, Physical Inactivity, Cardiovascular Diseases
- Trial name
- NCT06576349
- Testing
- Compassionate And Loving Mindset towards Heart Health Risk (CALM Hearts) Intervention
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Manitoba
Multiple Sclerosis, Relapsing-Remitting
Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis (RRMS)
The first major objective of this pilot trial is to demonstrate that it is possible to study myelin repair in relapsing-remitting multiple sclerosis (RRMS) patients with enhancing lesions on MRI by using advanced imaging…
- Trial name
- NCT02493049
- Testing
- Domperidone
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University of Calgary
Gestational Diabetes Mellitus
The Effect of Oral Probiotics on Glycemic Control of Women With Gestational Diabetes Mellitus
Scientific background: Uncontrolled gestational diabetes mellitus (GDM) is associated with severe maternal and neonatal morbidities. Treatment of GDM is multidisciplinary and includes lifestyle changes and medications.
- Trial name
- NCT03864549
- Testing
- Femina II
- Where
- 4 sites in Israel
- Volunteers
- 93 people
- Sponsor
- HaEmek Medical Center, Israel
Diminished Ovarian Reserve, Infertility, Female
Efficacy of Traditional Chinese Medicine on Ameliorating IVF-ET Outcomes of Diminished Ovarian Reserve Patients
Patients with diminished ovarian reserve (DOR) who undergo in vitro fertilization and embryo transfer (IVF-ET) are included as the research subjects.
- Trial name
- NCT05577455
- Testing
- Medical prescription before ovulation, Medical prescription after ovulation
- Volunteers
- 266 people
- Sponsor
- Peking University Third Hospital
Injuries, Spinal Cord, CVA (Cerebrovascular Accident)
Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS)
Comparing the efficacy of Intracthecal Baclofen dose between the Prometra II and Medtronic SynchroMed II for patients with spasticity and with current a current SyncroMed II pump needing replacement.
- Conditions
- Injuries, Spinal Cord, CVA (Cerebrovascular Accident), Traumatic Brain Injury, MS (Multiple Sclerosis)
- Trial name
- NCT04530955
- Testing
- Prometra II Programmable Pump - Flowonix Medical
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Culicchia Neurological Clinic
Brain Tumor, Pediatric
Intensity Modulated PrOton Therapy in Pediatric BRain Tumors (IMPORT)
Children diagnosed with benign or low-grade brain tumors often require radiation therapy to control their disease. While radiation can be effective, traditional techniques using X-rays (photon-based radiotherapy) expose healthy…
- Trial name
- IMPORT (NCT07338526)
- Testing
- Intensity-modulated proton therapy (IMPT), Photon-based intensity-modulated radiation therapy (IMRT).
- Where
- India
- Volunteers
- 94 people
- Sponsor
- Tata Memorial Centre
Renal Stone, Ureter Stone
Comparison Between 6Fr Vs 4Fr Double J Stent
Double J (DJ) Stenting is a commonly done procedure in endourology to ensure ureteric patency following Urological Interventions. DJ stents are available in various sizes.
- Trial name
- NCT05725226
- Testing
- Double J Stent 6Fr x 26cms, Double J Stent 4Fr x26cms
- Where
- Nepal
- Volunteers
- 110 people
- Sponsor
- Tribhuvan University, Nepal
Vaginal Atrophy, Vaginal Relaxation
Evaluation of Efficacy and Safety of Votiva for Vaginal Rejuvenation
This is a multi-site, randomized, prospective study designed to evaluate the safety and efficacy of the Votiva device headpieces through radiofrequency for vaginal rejuvenation.
- Conditions
- Vaginal Atrophy, Vaginal Relaxation, Stress Urinary Incontinence
- Trial name
- NCT03520426
- Testing
- Votiva RF
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Walden, Jennifer L., M.D.,P.L.L.C.
Thrombocytopaenia
SB-497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adult Cancer Patients Receiving Chemotherapy
SB497115 is an oral agent which activates the thrombopoietin receptor and increases platelet counts in healthy volunteers. This study is examining several different doses of SB497115 versus placebo as treatment for patients with…
- Trial name
- NCT00102726
- Testing
- SB497115
- Where
- 95 sites in United States, Argentina and 17 more
- Volunteers
- 183 people
- Sponsor
- GlaxoSmithKline
Myopia
The Effect of +3.00ADD on Myopia Progression in Chinese Children
The purpose of this study is to evaluate the effect of +3.00ADD vs single vision spectacle on the progression of myopia in children.
- Trial name
- NCT03242226
- Testing
- two spectacles, single vision spectacles
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Estazolam-dependent Insomnia
A Randomized Controlled Trial of Auricular Acupressure in Treating Estazolam-dependent Insomnia
Insomnia is a disorder characterized by difficulties in falling asleep, maintaining sleep or waking up too early, and impairment of daytime functioning.
- Trial name
- ESAAEDI (NCT06258226)
- Testing
- Conventional dosage reduction, Auricular acupressure
- Volunteers
- 108 people
- Sponsor
- Wenzhou Central Hospital
Ascites Hepatic
"Exploring the Potential Benefits of Using Dapagliflozin in Cirrhotic Chronic Liver Disease Patients- A Randomized Controlled Trial"
This study aims to evaluate beneficial effects of using dapagliflozin in cirrhotic chronic liver disease patients. We hypnotized that the use of dapagliflozin will be associated with fewer need for large volume paracentesis hence…
- Trial name
- NCT07684326
- Testing
- Dapagliflozin
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Beni-Suef University
Colon Cancer, Rectal Cancer
Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer Survivors
This phase II, randomized pilot trial studies the effect of the consumption of foods made with resistant starch compared to foods made with corn starch on biomarkers that may be related to colorectal cancer progression in stage…
- Conditions
- Colon Cancer, Rectal Cancer, Cancer Survivor, Colorectal Adenocarcinoma
- Trial name
- NCT03781778
- Testing
- Dietary Intervention (resistant starch), Dietary Intervention (regular starch), Questionnaire Administration
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Fred Hutchinson Cancer Center
Physical Functional Performance, Psychological Health
Interactive Exergaming With Otago Exercise Program on Mobility in Community-Dwelling Older Adults
This clinical trial aims to evaluate the effectiveness of interactive exergaming combined with Otago Exercise Program on mobility among community-dwelling older adults aged 65 and above.
- Conditions
- Physical Functional Performance, Psychological Health, Physical Fitness, Mobility Limitation
- Trial name
- GAME-OEP (NCT06814678)
- Testing
- Interactive Exergaming with Otago Exercise Program, Control Group with Usual Care
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University
Behcet Syndrome
Zinc Supplementation and Behçet's Syndrome
To study the effects of zinc gluconate supplementation on patients with Behçet's syndrome, 50 patients will be randomly allocated to two groups: placebo group or zinc group (one tablet of 30 mg/day elemental zinc) for 12 weeks.
- Trial name
- NCT05098678
- Testing
- Zinc gluconate
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Tabriz University of Medical Sciences
Obsessive-Compulsive Disorder and Symptoms
Brief Anxiety Sensitivity Treatment for Obsessive Compulsive Symptoms
Obsessive-compulsive disorder (OCD), characterized by recurrent obsessions and/or compulsions, is a disabling psychiatric condition affecting approximately 2-3% of the population.
- Trial name
- COAST (NCT02635178)
- Testing
- Cognitive Anxiety Sensitivity Treatment, Physical Health Education Training
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Florida State University
Heart Failure, Overweight and Obesity
Mobile Applet for Weight Management in Obese Heart Failure Patients
The objective of this clinical trial is to investigate the effect of weight reduction through a diet management application and an intelligent weight scale on a composite cardiovascular endpoint in obese patients with heart…
- Conditions
- Heart Failure, Overweight and Obesity, Weight Loss, Heart Failure With Reduced Ejection Fraction
- Trial name
- IDEAL-HF (NCT06455878)
- Testing
- Full usage of diet management app group and with the full usage of an intelligent weight scale, Limited usage of diet management app group and with the limited usage of an intelligent weight scale
- Where
- 26 sites in China
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Heart Health Research Center
Anxiety, Pain
Effect of the 4-7-8 Breathing Technique Before Central Venous Catheter Insertion
Purpose: This study aims to evaluate the effect of the 4-7-8 breathing technique applied before central venous catheter (CVC) insertion on patients' anxiety, pain, and vital signs.
- Conditions
- Anxiety, Pain, Vital Sign Evaluation, 4-7-8 Breathing Technique
- Trial name
- NCT07917585
- Testing
- 4-7-8 breathing technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mersin University
Breast Cancer
A Clinical Study of Hetrombopag Olamine Tablets for Thrombocytopenia Induced by Anti-tumor Treatment in Advanced Breast Cancer
This study now plans to explore the efficacy and safety of hetrombopag in cancer therapy-induced thrombocytopenia in advanced breast cancer, so as to further guide the clinical application of hetrombopag in chemotherapy-induced…
- Trial name
- NCT05394285
- Testing
- Hetrombopag
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Henan Cancer Hospital
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