Clinical trials: CONTROL Condition
Attention-Deficit/Hyperactivity Disorder
A Trial of Centanafadine Efficacy and Safety in Adolescents With Attention- Deficit/Hyperactivity Disorder
This trial was conducted to evaluate the efficacy and safety of the Centanafadine once daily (QD) extended release (XR) capsules in adolescent participants (13 - 17 years, inclusive) with attention-deficit/hyperactivity disorder…
- Trial name
- NCT05257265
- Testing
- Centanafadine Hydrochloride
- Where
- United States
- Volunteers
- 459 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Ovarian Neoplasms
A Study Comparing Niraparib Versus Platinum-Taxane Doublet Chemotherapy as Neoadjuvant Treatment in Participants With Homologous Recombination-Deficient Stage III/IV Ovarian Cancer (COHORT-C)
The goal of the study is to learn whether Niraparib or Platinum-Taxane Doublet chemotherapy is better in treating participants with Homologous Recombination Deficient (HRd) Stage III/IV Ovarian Cancer (OC).
- Trial name
- NCT06964165
- Testing
- Niraparib, Carboplatin, Paclitaxel
- Where
- 21 sites in United States, Canada and 1 more
- Volunteers
- 36 people
- Sponsor
- Tesaro, Inc.
Postoperative Cough, Lung Cancer
Maekmoondong-tang on Post-operative Cough in Patients With Lung Cancer
The aim of the present study is to evaluate the efficacy and safety of Maekmoondong-tang on post-operative cough in patients with lung cancer. A randomized, double-blind, placebo-controlled trial will be conducted.
- Trial name
- NCT03384667
- Testing
- Maekmoondong-tang
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seong-Gyu Ko
Meningitis, Cryptococcal, HIV Infections
Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis
The purpose of this study is to examine the antifungal activity of recombinant interferon-gamma 1b (rIFN-gamma 1b) given with standard antifungal therapy.
- Trial name
- NCT00012467
- Testing
- Itraconazole, Flucytosine, Fluconazole
- Where
- 9 sites in United States, Peru
- Volunteers
- 60 people
- Sponsor
- InterMune
Asthma
Clinical Study on the Efficacy and Safety of SHR-4597 Inhalant in Adult Patients With Asthma
To evaluate the efficacy and safety of SHR-4597 inhalants in adults with asthma: a multicenter, randomized, open-label, positive-controlled Phase II clinical study
- Trial name
- NCT06940700
- Testing
- SHR4597, Budesonide inhalant
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangdong Hengrui Pharmaceutical Co., Ltd
Stroke, Inflammation
Combinating Fingolimod With Alteplase Bridging With Mechanical Thrombectomy in Acute Ischemic Stroke
Proof-of concept clinical trials have indicated that the sphingosine-1-phosphate receptor modulator fingolimod may be efficacious in attenuating brain inflammation and improving clinical outcomes in patients with AIS as a single…
- Trial name
- FAMTAIS (NCT02956200)
- Testing
- Fingolimod
- Where
- China
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hot Flashes, Acupuncture Therapy
Effectiveness of Electro-Press Needle and Gamma-Oryzanol for Menopause-associated Hot Flashes
The investigators plan to conduct the randomized controlled trial to evaluate the effectiveness of electro-press needle (EPN), a novel acupuncture needle combining shallow and gentle insertion with transdermal electrical…
- Conditions
- Hot Flashes, Acupuncture Therapy, Perimenopausal Disorder, Postmenopausal Symptoms
- Trial name
- NCT05922800
- Testing
- Electro Press Needle, Gamma-Oryzanol
- Volunteers
- 64 people
- Sponsor
- Dongzhimen Hospital, Beijing
Dermatitis, Atopic, Eczema
Skin Effects of a Topical Amino Acid Moisturizing Cream and Desonide in Atopic Dermatitis
The purpose of this study is to compare the effects of an amino acid moisturizing cream and desonide cream in reducing skin symptoms associated with AD/eczema in subjects with mild to moderate atopic dermatitis/eczema.
- Trial name
- NCT02286700
- Testing
- Desonide Cream, Amino Acid Moisturizing Cream
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- NeoStrata Company, Inc.
Dental Implant, Diabetes
RCT KS-SA Versur KS-BA in Diabetic Patients
The aim of this randomized controlled trial is to evaluate whether is better to place KS Osstem Implants with BA or SA surface placed in patients with type 2 diabetes, and to compare clinical and radiographic data.
- Trial name
- NCT05847907
- Testing
- Implant placement
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Università degli Studi di Sassari
Colonic Polyps, Colonic Neoplasms
Endo-cuff Assisted Vs. Standard Colonoscopy for Polyp Detection in Bowel Cancer Screening
The study evaluates whether the use of a novel endoscopic cap (the endo-cuff) at the tip of a colonoscope improves the numbers of polyps detected during bowel cancer screening colonoscopy.
- Trial name
- E-CAP (NCT02529007)
- Testing
- Endo-cuff, Standard colonoscopy
- Where
- United Kingdom
- Volunteers
- 534 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Celiac Disease
Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Relief of CeD Symptoms
To assess the efficacy and safety of larazotide acetate versus placebo for the relief of persistent symptoms in adult celiac disease patients.
- Trial name
- NCT03569007
- Testing
- Larazotide
- Where
- 160 sites in United States
- Volunteers
- 307 people
- Sponsor
- 9 Meters Biopharma, Inc.
Gastric Cancer, Surgery
3D-4K-ICG Laparoscopic Gastrectomy for Gastric Cancer
Patients with locally advanced gastric adenocarcinoma (CT2-4a N-/+ M0) were selected as study subjects to investigate the safety, efficacy, and feasibility of ICG near-infrared imaging tracing in 3D plus ultra high resolution…
- Trial name
- 3D-4K-ICG (NCT06161207)
- Testing
- Indocyanine Green Tracer Using in 3D plus Ultra High Resolution Laparoscopic Gastrectomy with Lymph Node Dissection
- Where
- China
- Volunteers
- 702 people
- Sponsor
- Fujian Medical University
Malocclusion, Angle Class II
Effect of Low-Intensity Pulsed Ultrasound on Functional Treatment of Class II Malocclusion
This experimental study will evaluate the effect of combined treatment with low-intensity pulsed ultrasound (LIPUS) and functional appliances (twin-block) on the correction of class II malocclusion, compared with the control…
- Trial name
- NCT03251807
- Testing
- Twin-block, LIPUS (Low-intensity pulsed ultrasound)
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Ischemic Stroke
Tongxinluo Capsule in Ischemic Stroke Patients（TISS)
The purpose of this study is to assess the effects in improving life self-care ability of stroke patients after taking Tongxinluo Capsule(within 72 hours after onset) versus Placebos for 90 days.
- Trial name
- NCT01919671
- Testing
- Tongxinluo capsule
- Where
- China
- Volunteers
- 2,007 people
- Sponsor
- yongjun wang
Diabetes Mellitus, Type 1
Smart MDI Study (CIP343)
The purpose of the study is to evaluate the effectiveness of the Smart MDI system with InPen™ and Simplera™ in comparison with Multiple Daily Injection (MDI) therapy with intermittent scanning or real-time Continuous Glucose…
- Trial name
- NCT06645834
- Testing
- Smart MDI System
- Where
- 18 sites in Belgium, Czechia and 4 more
- Volunteers
- 179 people
- Sponsor
- Medtronic MiniMed, Inc.
Overweight and Obesity
Sustaining the Reach of a Scalable Weight Loss Intervention Through Financial Incentives
This study seeks to assess how different incentive strategies may reduce the initial attrition gap when implementing weight management in a primary care clinic predominantly serving African American patients.
- Trial name
- NCT04225234
- Testing
- Financial incentives
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Nebraska
Myopia
Myopia Control With Simultaneous Vision Approach
To determine if the 'Defocus Incorporated Soft Contact' (DISC) lens slows myopia progression in Hong Kong schoolchildren using simultaneous vision approach.
- Trial name
- NCT00919334
- Testing
- Defocus Incorporated Soft Contact (DISC) lens
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Coronary Artery Disease, Percutaneous Coronary Intervention
Anti-platelet Effect of Berberine in Patients After Percutaneous Coronary Intervention
The APLABE-PCI is a single-center, randomized, open-label, controlled, dose-escalating, parallel-group study, which is designed to assess the anti-platelet effect of berberine in approximately 64 patients receiving aspirin and…
- Trial name
- APLABE-PCI (NCT03378934)
- Testing
- Berberine, Standard treatment, Aspirin
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking Union Medical College Hospital
Injuries, Pain
Randomized Double Blind Controlled Trial Comparing a Blind Sciatic Nerve Block in the Popliteal Fossa to Intravenous Morphine for Traumatic Severe Acute Pain in the Prehospital Setting
The purpose of the study is to determine the efficacity of a simple blind technic of loco regional anaesthesia of the sciatic nerve compared to the gold standard in emergency medecine : the intravenous morphine for treated the…
- Conditions
- Injuries, Pain, Emergencies
- Trial name
- BPOP (NCT01522534)
- Testing
- Mepivacaine, Morphine
- Where
- 6 sites in France
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Intracranial Hypertension
Comparison of the Effects of Deep and Moderate Neuromuscular Blockade on Optic Nerve Sheath Diameter
Increased intracranial pressure (IICP) is a common problem in traumatic brain injuries and many medical diseases. Early recognition of IICP can save lives.
- Trial name
- MBLONDE (NCT04211064)
- Testing
- Ultrasonographic measurement of optic nerve sheath diameter, Deep neuromuscular block, Moderate neuromuscular block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
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