Clinical trials: CONTROL Condition
Opioid-Induced Bowel Dysfunction, Constipation
The Effect of Naldemedine on Opioid-induced Bowel Dysfunction
Opioid-induced bowel dysfunction is a frequent condition during opioid therapy for chronic pain. Indeed, up to 90% of people on opioid treated patients experience constipation.
- Trial name
- NCT06334198
- Testing
- Naldemedine, Tramadol
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asbjørn Mohr Drewes
Dental Caries, Pulpotomy
BiodentineTM Versus Formocresol Pulpotomy Technique in Primary Molars
The objective of this clinical study was to prospectively compare the clinical and radiographic success rates of BiodentineTM pulpotomies versus formocresol pulpotomies in children vital primary molars.
- Trial name
- NCT03779698
- Testing
- BiodentineTM, Formocresol
- Where
- Saudi Arabia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Amyotrophic Lateral Sclerosis
Investigation of Cannabinoid 2-receptor Expression in the Brain and Spine of ALS-patients Compared to Healthy Controls With PET (18F-RoSMALS)
This clinical trial is a phase 1 study in which investigations with the weakly radioactive substance [18F]-RoSMA-18-d6 are being carried out for the first time.
- Trial name
- 18F-RoSMALS (NCT05880563)
- Testing
- [18F]-RoSMA-18-d6
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Markus Weber
Appetite Suppression, Weight Loss
Effects of a Dietary Fibre Supplementation of a Low Calorie Diet on Appetite and Body Weight
This 18 week, randomized, double blind, placebo controlled trial will examine the effects of thick dietary fibre (PGX) supplementation of a low calorie diet (LCD) on appetite, weight loss, body composition, and compliance in…
- Trial name
- NCT01109199
- Testing
- PolyGlycopleX (PGX), Rice flour
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Canadian Center for Functional Medicine
Charcot-Marie-Tooth Disease
A Study to Assess the Safety and Effectiveness of FLX-787 in Subjects With Charcot-Marie-Tooth Disease Experiencing Muscle Cramps.
The COMMIT Study will assess the safety and effectiveness of FLX-787 in men and women with Charcot-Marie-Tooth disease (CMT) experiencing muscle cramps.
- Trial name
- COMMIT (NCT03254199)
- Testing
- FLX-787-ODT (orally disintegrating tablet)
- Where
- 20 sites in United States
- Volunteers
- 27 people
- Sponsor
- Flex Pharma, Inc.
Stroke, Multiple Sclerosis
Mobility Enhancing Nursing Intervention
Objectives: This parallel RCT investigated the effect of a new nursing intervention (Mobility Enhancing Nursing Intervention - MFP) designed to improve the rehabilitation programs' outcomes and patients' quality of life.
- Trial name
- MFP (NCT02198599)
- Testing
- Mobility-enhancing-nursing intervention
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- Zurich University of Applied Sciences
Obesity, Overweight
PACE-CALL: A Weight Control Intervention for Survivors of Childhood Leukemia
The purpose of this National Cancer Institute (NCI) funded study is to develop and test the acceptability and usability of a web \& text message based weight loss intervention for childhood acute lymphoblastic leukemia (ALL)…
- Conditions
- Obesity, Overweight, Weight Loss, Weight Maintenance
- Trial name
- PACE-CALL (NCT01171599)
- Testing
- Fit4Life
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Diego
Hypertension, Cerebral Small Vessel Diseases
Songling Xuemaikang Capsules for Cerebral Small Vessel Disease
Cerebral small vessel disease (CSVD) is a common age-related microvascular disease related to the slow accumulation of damage to small arteries, veins, and capillaries.
- Trial name
- SXC-CSVD (NCT07271732)
- Testing
- Songling Xuemaikang Capsule
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Dongzhimen Hospital, Beijing
Amblyopia, Visual Training
A Randomized Controlled Trial of Autostereoscopic 3D Vision Therapy for Amblyopia
The goal of this clinical trial is to learn if an autostereoscopic 3D amblyopia training system works to improve vision in children and adolescents with amblyopia.
- Conditions
- Amblyopia, Visual Training, Visual Functions, Visual Health
- Trial name
- NCT07709832
- Testing
- Autostereoscopic 3D Training, Conventional Patching
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Beijing Tongren Hospital
Type 2 Diabetes Mellitus (T2DM)
Sitagliptin Mechanism of Action Study in Patients With Type 2 Diabetes Mellitus (0431-059)
A clinical study to determine the safety, efficacy and the way sitagliptin works in patients with Type 2 Diabetes Mellitus who have inadequate glycemic (blood sugar) control.
- Trial name
- NCT00704132
- Testing
- Comparator: sitagliptin phosphate
- Volunteers
- 57 people
- Sponsor
- Merck Sharp & Dohme LLC
Cardiometabolic Syndrome, Glucose Metabolism Disorders
The Effect of Flexitarian, Time-restricted Eating on Cardiometabolic Traits in Normal Weight, Young Men
The goal of this factorial randomized controlled trial is to find out whether time-restricted eating and flexitarian diet (on its own and combined) can improve cardiometabolic health markers in normal weight, young men with…
- Conditions
- Cardiometabolic Syndrome, Glucose Metabolism Disorders, Blood Pressure, Lipid Metabolism Disorders
- Trial name
- FlexiFast (NCT05762263)
- Testing
- Dietary
- Where
- Poland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury in Olsztyn
Heart Failure With Reduced Ejection Fraction, Iron Deficiency
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life(COREVIVE-HFrEF)
This study will address whether the additional use of Ferric Derisomaltose on top of standard care will improve exercise capacity and quality of life in patients with acute heart failure and iron deficiency.
- Conditions
- Heart Failure With Reduced Ejection Fraction, Iron Deficiency, Acute Heart Failure
- Trial name
- COREVIVE-HFrEF (NCT05971732)
- Testing
- Ferric derisomaltose
- Where
- China
- Volunteers
- 146 people
- Sponsor
- China-Japan Friendship Hospital
Children, Preschool, Pain and Anxiety
Storytelling Caterpillar - Pain, Anxiety, and Satisfaction
This randomized controlled trial aims to evaluate the effect of using the "Storytelling Caterpillar" toy on pain, anxiety, and parental satisfaction during blood draw procedures in children aged 3 to 6 years.
- Trial name
- SC-PAS (NCT07127432)
- Testing
- The Storytelling Caterpillar
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Koç University
Post-Measles Pneumonia, Measles
Prophylactic Antibiotics in Measles
Objective It is the objective to test whether the use of prophylactic antibiotics in measles infection will reduce the incidence of post-measles pneumonia and/or admissions to hospital with 50%.
- Trial name
- NCT00168532
- Testing
- Sulfamethoxazole-Trimethoprim
- Where
- Guinea-Bissau
- Volunteers
- 218 people
- Sponsor
- Bandim Health Project
Osteoarthritis of the Knee
MINIMALLY INVASIVE SURGERY in Total Knee Arthroplasty
Overall study design: A prospective, randomized, multi-center clinical studies comparing the minimal invasive and the standard surgical total knee replacement technique (control) using the Genesis II total knee system.
- Trial name
- MIS GEN II (NCT00853398)
- Testing
- surgical technique
- Where
- Germany
- Sponsor
- Smith & Nephew Orthopaedics AG
Knee Arthropathy, Knee Osteoarthritis
NLR and PLR Levels Following IPACK Block in Knee Arthroplasty
Effect of iPACK block on NLR and PLR following knee arthroplasty
- Conditions
- Knee Arthropathy, Knee Osteoarthritis, Knee Pain Chronic
- Trial name
- NCT06304298
- Testing
- 0.9% Sodium Chloride Injection, Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Hirschsprung Disease, Febrile Urinary Tract Infection (Disorder)
Does Hirschsprung Disease Increase the Risk of Febrile Urinary Tract Infection in Children
Febrile urinary tract infection (FUTIs) are the most common bacterial infections in children under the age of 2 years. They represent 7% of children presenting with fever without a source.
- Trial name
- NCT04837963
- Where
- France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Montpellier
Pancreatitis Relapsing
Simvastatin in the Prevention of Recurrent Pancreatitis
Recurrent acute pancreatitis and recurrent relapses of inflammation in chronic pancreatitis are an important problem. In some cases, prevention of these acute flares of inflammation is not possible.
- Trial name
- SIMBA-16 (NCT04021498)
- Testing
- Simvastatin 40mg
- Where
- Spain
- Volunteers
- 83 people
- Sponsor
- Enrique de-Madaria
Myocardial Infarction
Firibastat or Ramipril After Acute Myocardial Infarction for Prevention of Left Ventricular Dysfunction
This is a multicenter, randomized, double-blind, active-controlled, dose-titrating phase 2 study to evaluate the safety and efficacy of firibastat administered orally BID (2 daily doses) versus ramipril administered orally BID…
- Trial name
- QUORUM (NCT03715998)
- Testing
- Ramipril, Firibastat
- Where
- 7 sites in France, Germany and 5 more
- Volunteers
- 295 people
- Sponsor
- Quantum Genomics SA
Covid19
A Study to Evaluate the Efficacy and Safety of Proxalutamide (GT0918) in Hospitalized COVID-19 Subjects
This study is an adaptive Phase III randomized double-blind placebo-controlled trial to evaluate the efficacy and safety of Proxalutamide (GT0918) in hospitalized adults diagnosed with COVID-19.
- Trial name
- NCT05009732
- Testing
- GT0918, Standard of care
- Where
- 30 sites in United States, China and 3 more
- Volunteers
- 139 people
- Sponsor
- Suzhou Kintor Pharmaceutical Inc,
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.