Clinical trials: CONTROL Condition
Dental Plaque
Efficacy of a Triclosan Formulation to Control the Initial Subgingival Biofilm Formation
The aim of the study is to compare the effect of a suspension containing Triclosan in dynamic of the subgingival biofilm formation versus a Placebo suspension.
- Trial name
- NCT02192060
- Testing
- Test - Using of a suspension containing Triclosan, Control - Using of a suspension without Triclosan
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Parkinson's Disease
Tango for Treatment of Motor and Non-motor Manifestations in Parkinson's Disease.
Parkinson's disease involves many motor difficulties as well as non-motor ones. Recent research has strongly suggested that exercise is very important for Parkinson's disease.
- Trial name
- NCT01573260
- Testing
- Argentinean Tango classes, Simple pamphlet about the exercise in PD
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Bladder Cancer
A Study of Intravesical Qapzola (Apaziquone) as a Surgical Adjuvant in Participants Undergoing Transurethral Resection of Bladder Tumor (TURBT)
This is a randomized, multicenter, two-arm, double-blind, placebo-controlled study of Qapzola in participants with low- to intermediate-risk non-muscle invasive bladder cancer (NMIBC), assessed according to the 2016 American…
- Trial name
- NCT03224182
- Testing
- Qapzola
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Spectrum Pharmaceuticals, Inc
Peri-Implantitis
Peri-implantitis Surgical Regenerative Therapy Using Bovine Bone Substitute With Hyaluronic Acid
The study aimed to assess 6- and 12-months evaluation of clinical, microbiological, and radiography outcomes after performing peri-implantitis regenerative surgical therapy with the bovine bone substitute with or without…
- Trial name
- NCT05171582
- Testing
- Surgery 1 (Test group), Surgery 2 (Control group)
- Where
- Serbia
- Volunteers
- 25 people
- Sponsor
- Botiss Medical AG
Affect, Alcohol Consumption
Automated Telephone Follow-up in the Swedish Prison and Probation Services
The purpose of this study is to investigate whether automated telephony may be used for daily assessments of paroled offenders, and whether a brief intervention based on these daily assessments may result in a more positive…
- Conditions
- Affect, Alcohol Consumption, Substance Abuse
- Trial name
- NCT01727882
- Testing
- Brief feedback, Daily assessments
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Region Skane
Endometriosis, Uterine Fibroids
A Phase 1 Clinical Study to Evaluate the Effects of SHR7280 on the Pharmacokinetics of Midazolam, S-warfarin, Omeprazole, Digoxin, and Rosuvastatin in Healthy Subjects
The purpose of this study is to evaluate the effects of SHR7280 on the pharmacokinetics of midazolam, S-warfarin, omeprazole, digoxin and rosuvastatin in healthy subjects.
- Conditions
- Endometriosis, Uterine Fibroids, Assisted Reproduction
- Trial name
- NCT06949124
- Testing
- SHR7280 Tablets
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
General Medical Inpatient Conditions
IMPaCT (Individualized Management Towards Patient-Centered Targets)
The investigators propose a pilot randomized controlled trial of a care transitions intervention in which trained Community Health Workers will act as supports for socioeconomically vulnerable patients who are being discharged…
- Trial name
- PaCT (NCT01346462)
- Testing
- Patient-Centered Transition Intervention
- Where
- United States
- Volunteers
- 513 people
- Sponsor
- University of Pennsylvania
Pregnancy, Pregnancy-Related Pain
Integrated Medical, Surgical and Physiotherapy Care for Pregnant Women With Chronic Diseases
This non-randomized controlled quasi-experimental study evaluates the effectiveness of an integrated medical-surgical and physiotherapy community-based care model for pregnant women with chronic diseases.
- Conditions
- Pregnancy, Pregnancy-Related Pain, Musculoskeletal Disorders, Physical Therapy
- Trial name
- IMSP-PregCD (NCT07589946)
- Testing
- Physiotherapy-based Care, control group
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sinai University
Low-level Laser Acupuncture in Patients With Total Knee Arthroplasty
Low-level Laser Acupuncture Reduces Postoperative Pain and Morphine-related Side Effects in Patients With Total Knee Arthroplasty:
Total knee arthroplasty is a common and effective surgical procedure for patients with end-stage knee osteoarthritis, and wound pain is still a problem for many of the patients.
- Trial name
- NCT03995446
- Testing
- low-level laser
- Where
- Taiwan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Post Operative Pain
Ultrasound-guided Transversus Abdominis Plane Block After Hysterectomy
In this randomized, controlled, observer-blinded study we plan to evaluate ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management in patients undergoing abdominal hysterectomy.
- Trial name
- TAP (NCT01153503)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Autism Spectrum Disorder (ASD), Autism
Xenon Therapy for Children With Autism Spectrum Disorder
This study aims to evaluate the efficacy and safety of inhaled xenon for the treatment of children with autism spectrum disorder (ASD).
- Trial name
- ASD; Xe (NCT07435103)
- Testing
- Xenon
- Where
- China
- Volunteers
- 72 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Infertility
Trial Comparing hCG Triggering Versus hCG Associated With GnRH Agonist
The purpose of this study is to see whether patients triggered with only human Chorion Gonadotropin (hCG) have higher number of Metaphase II oocytes (MII) and implantation rate than patients triggered with hCG combined with…
- Trial name
- NCT01607203
- Testing
- Decapeptyl Daily, pregnyl
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- AZ Jan Palfijn Gent
Breast Cancer
Study to Examine the Effect of HKI-272 on Rhythms of the Heart (Cardiac Repolarization)
The purpose of this study is to determine whether HKI-272 affects the rhythms of the heart (cardiac repolarization).
- Trial name
- NCT00708903
- Testing
- neratinib, Moxifloxacin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Puma Biotechnology, Inc.
Asthma
Effect of a Mobile App on Improving Asthma Control in Patients With Persistent Asthma
mINSPIRERS_RCT aims to assess the magnitude of the effect of a mobile app for improving asthma control in adolescents and adults with persistent asthma, followed at primary and secondary care in Portugal.
- Trial name
- mINSPIRERS_RCT (NCT05129527)
- Testing
- InspirerMundi app, Usual care
- Where
- Portugal
- Volunteers
- 124 people
- Sponsor
- Universidade do Porto
Diabetes Mellitus, Type 2
Lantus Versus NPH: Comparison in Insulin Naive People Not Adequately Controlled With at Least One Oral Anti Diabetics (OAD) Treatment
Primary Objective: To demonstrate the superiority of insulin glargine over insulin NPH (Neutral Protamin Hagedornon) the change in HbA1c from baseline to the end of the treatment period.
- Trial name
- LANCELOT (NCT00949442)
- Testing
- Insulin Glargine (HOE901) [Lantus], Glimepiride, human insulin [NPH]
- Where
- 87 sites in Brazil, Czechia and 15 more
- Volunteers
- 708 people
- Sponsor
- Sanofi
Depression, Type 2 Diabetes Mellitus
Vortioxetine vs Sertraline in Mexicans
Depression in patients with type 2 diabetes is often undiagnosed and remains untreated, leading to poor therapy adherence and ill health-related outcomes.
- Trial name
- NCT03978286
- Testing
- Vortioxetine, Sertraline
- Volunteers
- 21 people
- Sponsor
- Universidad Juárez Autónoma de Tabasco
Shoulder Pain
Effectiveness of Pain Education Elderly Subacromial Pain
Objective: To verify the effectiveness of education in pain added to other treatment modalities (manual therapy and exercises) in the outcomes of pain, functionality, depression, anxiety, stress, kinesiophobia, self-efficacy and…
- Trial name
- Subacromial (NCT04941586)
- Testing
- Education in pain, Manual Therapy and Exercises, Manual Therapy and Exercises
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Rodrigo Gustavo da Silva Carvalho
Irritable Bowel Syndrome With Diarrhea (IBS-D)
G-PUR® for Symptomatic Treatment in Irritable Bowel Syndrome With Diarrhea
A randomized, double-blind, placebo-controlled pilot study in patients with IBS-D according to Rome IV criteria evaluating the clinical efficacy and safety of oral administration of 2g G-PUR® tid compared to placebo in a cohort…
- Trial name
- NCT04138186
- Testing
- 2.0g G-PUR®, oral administration
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Glock Health, Science and Research GmbH
Chronic Kidney Disease Requiring Chronic Dialysis, Sarcopenic Obesity
Oral Nutritional Supplement Intervention Among Hemodialysis Patients With Sarcopenic Obesity
Chronic kidney disease patients with sarcopenic obesity are noted to have impairment in physical performance and reducing their quality of life, and the investigators also founded these patients are at higher risk of mortality.
- Conditions
- Chronic Kidney Disease Requiring Chronic Dialysis, Sarcopenic Obesity, Body Composition
- Trial name
- NCT03347773
- Testing
- ReGen 18%
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Atopic Disease (Including Allergic Conjunctivitis)
A Multi-Center Study Evaluating the Safety of AC-170 0.24%
The purpose of this study is to evaluate the safety of AC-170 0.24% used twice daily in Healthy Adult Subjects and in Pediatric subjects with a history or family history of atopic disease (including allergic conjunctivitis).
- Trial name
- NCT02132169
- Testing
- Drug: AC-170 0.24%, AC-170 0%
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- Aciex Therapeutics, Inc.
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