Clinical trials: COPD
COPD
Long-term Activity Coaching in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality and morbidity around the world. Studies revealed that patients with COPD are less active than age-matched healthy controls and activity level decreases…
- Trial name
- NCT04139200
- Testing
- Type 1 physical activity tele coaching intervention, Type 2 physical activity tele coaching intervention
- Where
- 2 sites in Belgium
- Volunteers
- 150 people
- Sponsor
- KU Leuven
COPD
Home-based Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease
This project aims to assess the short-term effectiveness and responsiveness of a home-based pulmonary rehabilitation (PR) program (reabilitAR) in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT04722224
- Testing
- Home-based pulmonary rehabilitation
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Polytechnic Institute of Porto
COPD, Healthy
Femoral Artery Blood Flow During Rest and One-leg Knee Extensor Exercise in Patients With COPD
Doppler ultrasound is generally considered to provide reliable femoral blood flow measurements between rest and exercise, and the blood flow response to exercise is widely believed to be reduced in patients with chronic…
- Conditions
- COPD, Healthy, Chronic Obstructive Pulmonary Disease
- Trial name
- COPD-DOPPLER (NCT06135701)
- Testing
- One-legged knee-extensor exercise with Doppler measurements
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COPD Exacerbation, COPD Exacerbation Acute
Prehospital Non-invasive Ventilation for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The goal of this clinical trial is to test if treatment with prehospital Non-invasive ventilation (NIV) for patients with acute respiratory failure (ARF), due to acute exacerbation of chronic obstructive pulmonary disease…
- Conditions
- COPD Exacerbation, COPD Exacerbation Acute, Noninvasive Ventilation, Emergency Medical Services
- Trial name
- PRENIV (NCT06211920)
- Testing
- Non-invasive ventilation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Central Denmark Region
COPD Exacerbation, Hypercapnia
Comfort of Patients Under Non Invasive Ventilation According to the Mask
A sub-nasal mask with a skirt that fits the nostrils and with a dedicated port for the nasogastric tube has recently been introduced. This interface has never been compared to nasal-oral masks.
- Conditions
- COPD Exacerbation, Hypercapnia, Hypoventilation Obesity Syndrome, Acute Respiratory Failure
- Trial name
- ComPaNIV (NCT06212180)
- Testing
- mask
- Where
- 3 sites in France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COPD, Coping
Health-promoting Competence, Coping and Quality of Life in Patients With COPD
Chronic obstructive pulmonary disease (COPD) is a major cause of mortality and disability, and by 2020, it is expected to be the third leading cause of mortality worldwide.
- Conditions
- COPD, Coping, Quality of Life
- Trial name
- REKV-13/1741 (NCT02479841)
- Testing
- Self management program
- Where
- Norway
- Volunteers
- 225 people
- Sponsor
- Helse Fonna
COPD, Osteoporosis
Thoracic Kyphosis and Osteoporosis: Study of Their Relationship With Respiratory Functions in Chronic Obstructive Pulmonary Disease.
Chronic Obstructive Pulmonary Disease (COPD) is a condition characterized by a progressive and incompletely reversible limitation of airborne gas flow .
- Conditions
- COPD, Osteoporosis, Kyphosis
- Trial name
- CYPHOS (NCT04757714)
- Testing
- The high-resolution peripheral scanner (HRpQCT) of the tibia and radius, a low-dose imaging system exploration of their thoraco-lumbar spine (EOS system), Questionnaires
- Where
- France
- Sponsor
- Centre Hospitalier Régional d'Orléans
COPD
Physical Function in Patients With Chronic Obstructive Pulmonary Disease
The aims of the study are to examine the responsiveness of, and the correlation between field walk tests and physical performance test in patients with chronic obstructive pulmonary disease (COPD) after participating in pulmonary…
- Trial name
- NCT04107831
- Testing
- Pulmonary rehabilitation
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Haukeland University Hospital
Cystic Fibrosis, Asthma
Segmentation of Structural Abnormalities in Chronic Lung Diseases
Lung structural abnormalities are complex, time-consuming, and may lack reproducibility to evaluate visually on CT scans. The study's aim is to perform automated recognition of structural abnormalities in CT scans of patients…
- Conditions
- Cystic Fibrosis, Asthma, COPD, Interstitial Lung Disease
- Trial name
- NOVAA (NCT04760548)
- Testing
- Observational study
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Hôpital Haut Lévêque
COPD
Detect and Infer the Severity of COPD by Intelligent Terminal Device
Chronic obstructive pulmonary disease (COPD) is one of the most common respiratory diseases. Early detection and treatment are critical to prevent the deterioration of COPD.
- Trial name
- NCT05551169
- Where
- 10 sites in China
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
COPD
Effects of Blow Bottle Verses ACBTs Technique in Patients of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease is a common disease worldwide. Pulmonary rehabilitation is an important part to decrease the complications of COPD.
- Trial name
- NCT06189196
- Testing
- BLOW BOTTLE, ACBT
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
COPD Exacerbation
Risk Stratifying COPD Exacerbations
To identify clinical characteristics on presentation which predict differential outcomes in patients with exacerbation of COPD.
- Trial name
- ProECOPD_23 (NCT05852327)
- Testing
- Observation only
- Where
- 2 sites in Hong Kong
- Volunteers
- 500 people
- Sponsor
- Pamela Youde Nethersole Eastern Hospital
COPD Exacerbation Acute
Comparison of Bronchodilator Treatment Practices in Group E COPD Patients
COPD is a heterogeneous condition caused by airway (bronchitis/bronchiolitis) or alveolar (emphysema) abnormality, changes with chronic respiratory changes (dyspnea, dyspnoea, phlegm).
- Trial name
- NCT06178068
- Testing
- Comparison of bronchodilator effectiveness of nebulizer therapy devices
- Volunteers
- 39 people
- Sponsor
- Ataturk University
COPD, Tetrahydrobiopterin Deficiency
O2 Transport and Utilization in Health and Lung Disease
Skeletal muscle dysfunction is a frequent and clinically relevant systemic manifestation of Chronic Pulmonary Obstructive Disease (COPD), which is still poorly understood.
- Conditions
- COPD, Tetrahydrobiopterin Deficiency, Oxidative Stress
- Trial name
- NCT04014712
- Testing
- Tetrahydrobiopterin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Asthma, COPD
A Clinical Study in Healthy Subjects to Evaluate 9MW1911 Injection
This is a Phase 1, randomized, placebo-controlled study, enrolling approximately 38 healthy adult subjects (18-65 yrs). The purpose of this study is to evaluate the safety, tolerability and PK of single ascending dose of 9MW1911…
- Conditions
- Asthma, COPD, Atopic Dermatitis
- Trial name
- NCT05170243
- Testing
- 9MW1911 Injection
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mabwell (Shanghai) Bioscience Co., Ltd.
COPD
Activity, Balance and COPD (ABCOPD)
This research project incorporates a series of studies to investigate the relationship between physical performance (e.g. tests of strength, balance and walking distance) and physical activity (activity measured in day to day…
- Trial name
- ABCOPD (NCT04006015)
- Testing
- No intervention being delivered.
- Where
- United Kingdom
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Chronic Obstructive Pulmonary Disease, Emphysema or COPD
The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility
In some patients with chronic obstructive pulmonary disease (COPD) the breathlessness is caused by hyperinflation of the lungs. This causes difficulty breathing air out and makes it harder to breath in new air and limits the…
- Trial name
- NCT06163131
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Aarhus University Hospital
COPD Exacerbation
Study to Identify the Reduction of Exacerbations Resulting in Hospital Admission in Patients With COPD.
identification of the reduction of exacerbations resulting in hospital admission in COPD patients after the use of the Breath Detect telemedicine platform.
- Trial name
- BDS (NCT05440188)
- Testing
- Breath Detect Platform
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universidad Autonoma de Madrid
COPD (Chronic Obstructive Pulmonary Disease), CHF (Congestive Heart Failure)
A Pilot Observation and Feasibility Study of Prevora, Integrated Into Homecare Visits of High-risk Adults
Prevora is an antiseptic medication and dental treatment approved by Health Canada for reducing root decay (cavities) in adults at high risk of dental decay. An antiseptic kills germs and harmful bacteria.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), CHF (Congestive Heart Failure), Dialysis, Chronic Metabolic Disorder
- Trial name
- NCT06158633
- Testing
- Prevora
- Volunteers
- 30 people
- Sponsor
- CHX Technologies Inc.
COPD
Evaluation of Airway Gene Expression in COPD and Controlled Populations
To explore potential proteins that may be used to develop novel therapies for COPD. This will be accomplished by acquiring material from the lower respiratory tract via endobronchial brushings.
- Trial name
- NCT00571792
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nebraska