Clinical trials: COPD (Chronic Obstructive Pulmonary Disease)
Pulmonary Disease, Chronic Obstructive
Determining Optimal Free Dose Combination of Tiotropium Bromide and BI 1744 CL in Chronic Obstructive Pulmonary Disease (COPD)
The primary objective of this study is to determine the optimum once daily dose of BI 1744 CL and tiotropium in free dose combination (delivered by the Respimat inhaler) after four week treatment in patients with COPD.
- Trial name
- NCT01040403
- Testing
- olodaterol (BI 1744) low, low tiotropium bromide, olodaterol (BI 1744) high
- Where
- 33 sites in Canada, Germany and 2 more
- Volunteers
- 233 people
- Sponsor
- Boehringer Ingelheim
COPD
Objective Assessment of Adherence to Inhalers by COPD Patients
Rationale: Objective adherence to inhaled therapy by patients with chronic obstructive pulmonary disease (COPD) has not been reported.
- Trial name
- NCT04025242
- Volunteers
- 244 people
- Sponsor
- Beaumont Hospital
Pulmonary Disease, Chronic Obstructive
Efficacy and Safety of Tiotropium and Atrovent in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
To compare the bronchodilator efficacy and safety of tiotropium inhalation capsules (18 µg once daily) and Atrovent® MDI (2 puffs of 20µg q.i.d.) among Filipino patients with COPD
- Trial name
- NCT02172469
- Testing
- Tiotropium inhalation powder capsule, Ipratropium Bromide Metered Dose Inhaler
- Volunteers
- 215 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Long-term Oxygen Treatment (LTOT) in Chronic Obstructive Pulmonary Disease: Factors Influencing Survival
The purpose of this prospective cohort study is to determine factors involved in survival in new COPD patients treated by long-term oxygen therapy. Background: long-term oxygen therapy is indicated in patients with severe COPD.
- Trial name
- NCT00871962
- Testing
- OXYGEN SUPPLEMENTATION
- Where
- France
- Volunteers
- 750 people
- Sponsor
- Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Chronic Obstructive Pulmonary Disease
Observational Study to Evaluate Health Status of Chronic Obstructive Pulmonary Disease (COPD) Patients in Response to Real-life Treatments in Thailand
The purpose of this study is to evaluate health status of uncontrolled Chronic Obstructive Pulmonary Disease (COPD) patients in response to treatments in clinical practice.
- Trial name
- NCT01169727
- Where
- 20 sites in Thailand
- Volunteers
- 684 people
- Sponsor
- AstraZeneca
Pulmonary Disease, Chronic Obstructive
Testing Cognitive Functions in Patients With COPD Using a Driving Simulator
Little is known about the causes and degree of cognitive dysfunction in patients with Chronic Obstructive Pulmonary Disease (COPD), especially their driving abilities.
- Trial name
- NCT02740673
- Testing
- Driving simulator
- Where
- Denmark
- Sponsor
- Aarhus University Hospital
COPD
Influence of PESF on Oxygen Saturation, Quality of Life and Exercise Capacity in COPD
The effect of PESF (Pulsating Electrostatic Field) on the oxygen saturation, quality of life and the exercise capacity will be studied in a randomized, dubbel blind, placebo-controlled parallel design with 32 COPD patients GOLD…
- Trial name
- NCT03797794
- Testing
- Pulsating Electrostatic Field
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- University Medical Center Groningen
Chronic Obstructive Pulmonary Disease, Respiratory Disease
A Wireless Bed Sensor for Monitoring Coughs
Aging of the population is dramatically increasing the number of hospitalized patients, with the consequent challenges of limited medical personnel and resources in hospitals.
- Trial name
- "MoniToux" (NCT03177694)
- Testing
- Wireless bed sensor
- Volunteers
- 20 people
- Sponsor
- Ligue Pulmonaire Neuchâteloise
Asthma, COPD
Bioequivalence Study to Assess Systemic Exposure of FP and SAL FDC From Different DPIs
This is a crossover study to assess the systemic pharmacokinetics of fluticasone propionate (FP) and salmeterol (SAL). Study medication will be administered as fixed dose combinations (250 µg FP and 50 µg SAL) from the Advair®…
- Trial name
- NCT02215122
- Testing
- MGR001, Advair® Diskus®, Seretide™ Accuhaler™
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mylan Pharma UK Ltd.
Pulmonary Disease, Chronic Obstructive
Comparative Study of Fluticasone Furoate(FF)/Umeclidinium Bromide (UMEC)/ Vilanterol (VI) Closed Therapy Versus FF/VI Plus UMEC Open Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
This multicenter study will be conducted to compare the effect of FF/UMEC/VI with FF/VI plus UMEC on lung function after 24 weeks of treatment.
- Trial name
- NCT02729051
- Testing
- FF/UMEC/VI, FF/VI, UMEC
- Where
- 127 sites in Argentina, Australia and 10 more
- Volunteers
- 1,055 people
- Sponsor
- GlaxoSmithKline
Dyspnea
Walking Football for People With Chronic Breathlessness
The objective of this study is to evaluate the feasibility of a walking football intervention for people with chronic breathlessness.
- Trial name
- NCT05575102
- Testing
- Walking Football
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Teesside University
Multimorbidity, Population Medicine
Impact of Multi-Component Interventions on High Risk COPD Population
Study Participants: High-risk COPD population, defined as individuals whose score of COPD-SQ is 16 and above and whose age is 35 and above.
- Conditions
- Multimorbidity, Population Medicine, Chronic Obstructive Pulmonary Disease
- Trial name
- POPMIX-COPD (NCT06456996)
- Testing
- Multi-component intervention package
- Where
- China
- Volunteers
- 9,319 people
- Sponsor
- Peking Union Medical College
Severe Mental Disorder, Smoking Cessation
Tobacco Intensive Motivational and Estimate Risk
Randomized, open label, prospective study with a 12-month follow-up period. The primary objective evaluates the effectiveness of an intensive anti-smoking programme that informs patients of their individual risk of lung damages…
- Conditions
- Severe Mental Disorder, Smoking Cessation, COPD
- Trial name
- NCT03583203
- Testing
- personalized information about lung damage
- Where
- Spain
- Volunteers
- 230 people
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
COPD
Rhodiola Crenulata as an Adjunctive Therapy in COPD
We hypothesize that add-on Rhodiola L extract capsule to the regimen of patients with moderate-to-severe COPD (1) may provide a potential of systemic effects of anti-inflammation and anti-oxidation for these patients, and these…
- Trial name
- COPD (NCT02242461)
- Testing
- Rhodiola Crenulata
- Where
- Taiwan
- Volunteers
- 57 people
- Sponsor
- Chung Shan Medical University
Chronic Obstructive Pulmonary Disease
Change of Inspiratory Peak Flow in COPD
Chronic obstructive bronchitis and emphysema (COPD) are pathophysiologically characterized by inflammatory and structural changes in the lung.
- Trial name
- NCT00561886
- Testing
- Formoterol
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johannes Gutenberg University Mainz
COPD, COPD (Chronic Obstructive Pulmonary Disease)
Pulmonary Rehabilitation Frequency in COPD Patients
Chronic obstructive pulmonary disease (COPD) is a common condition that can cause breathlessness and reduced physical capacity. Pulmonary rehabilitation (PR) is an effective treatment, but traditional programs often require…
- Trial name
- NCT07575841
- Testing
- Pulmonary Rehabilitation
- Volunteers
- 158 people
- Sponsor
- Hospital Universitario Fundación Alcorcón
COPD
Causes of Appetite Loss in Patients With Chronic Obstructive Pulmonary Disease (COPD)
The project looks at causes of appetite loss in patients with COPD. It is know that active systemic inflammation can lead to appetite loss and COPD is classified as a disease lead by inflammation.
- Trial name
- NCT04754256
- Testing
- Council of Nutrition Appetite Questionnaire - test for applicability in Danish COPD patients
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Jens Rikardt Andersen
Pulmonary Disease, Chronic Obstructive
A Study for GSK3862995B in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease
The primary objective of the study is to investigate the safety and tolerability of ascending doses of GSK3862995B following single dose in healthy participants and repeat doses in participants with Chronic obstructive pulmonary…
- Trial name
- NCT06154837
- Testing
- GSK3862995B
- Where
- 32 sites in United States, Germany and 1 more
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Shortness of Breath
Effect of Senobi Versus Buteyko Technique on Functional Performance of Chronic Obstructive Pulmonary Disease Patient.
Effect of Senobi breathing exercise versus Buteyko breathing technique on functional performance among chronic obstructive pulmonary patient.
- Trial name
- NCT06196957
- Testing
- pursed lip breathing
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Hypoxemia, COPD
The Effectiveness of Two Distinct Ventilation Strategies Escalating Positive End Expiratory Pressure (PEEP) and Lung Recruitment Maneuvers in Improving Oxygenation
This study evaluates and compares the effectiveness of two distinct ventilation strategies-escalating PEEP and lung recruitment maneuvers-in improving oxygenation (i.e., managing hypoxemia) in COPD patients undergoing VATS.
- Trial name
- NCT06847412
- Testing
- Escalating PEEP, Sustained inflation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
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