Clinical trials: COPD (Chronic Obstructive Pulmonary Disease)
Chronic Obstructive Pulmonary Disease
Cross-sectional Study to Investigate the Effects of Chronic Obstructive Pulmonary Disease on Daily Life Activities
The purpose of this study is to investigate the effects of Chronic Obstructive Pulmonary Disease (COPD) on daily life activities in patients with COPD and also to determine the socio-demographic profile, daily life style and…
- Trial name
- COPD LIFE (NCT01325948)
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 497 people
- Sponsor
- AstraZeneca
COPD, COVID-19
Impact of COVID-19 on Lung Function in COPD Patients.
Background: In 2019, a novel coronavirus (SARS-COV2) was detected in Wuhan, China as a cause of acute respiratory distress syndrome (COVID-19).
- Trial name
- EspirCOVID (NCT05770440)
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Acute Respiratory Distress Syndrome (ARDS), Pneumonia
Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.
Pre-market clinical trial on 81 aldults participants to evidence safety and performance of the non-CE-marked medical device INBENTUS VERSATILE ventilator.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Pneumonia, COPD (Chronic Obstructive Pulmonary Disease), Postoperative Respiratory Distress
- Trial name
- NCT07432191
- Testing
- INBENTUS VERSATILE
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Iconic Solutions By Murcia SL
Chronic Obstructive Pulmonary Disease
Vowel Segmentation for Classification of Chronic Obstructive Pulmonary Disease Using Machine Learning
This work aims to evaluate whether the segmentation of vowel recordings collected from patients diagnosed with COPD and healthy control groups can increase the classification precision of machine learning techniques.
- Trial name
- NCT06160674
- Testing
- COPD
- Where
- Sweden
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Tolerability Study in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients
Efficacy and tolerability study in severe chronic obstructive pulmonary disease (COPD) patients.
- Trial name
- SECURE2 (NCT01415518)
- Testing
- Drug: Budesonide/formoterol (Symbicort Turbuhaler, Drug: ipratropium (AtroventTM), theophylline SR
- Where
- 21 sites in China
- Volunteers
- 581 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
A Study on the Microcirculatory Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With COPD
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04045418
- Testing
- Laser doppler
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhejiang Chinese Medical University
Emphysema
Ventilation-Perfusion Discrepancy Index Versus Conventional Anatomic-Physiologic Assessment for Target Lung Lobe Selection in Endobronchial Valve Placement: A Multicenter, Randomised Controlled Trial
The goal of this clinical trial is to learn if a Ventilation-Perfusion Discrepancy Index (VQDI)-guided strategy for selecting the target lung lobe can improve outcomes compared to the standard strategy in patients with severe…
- Trial name
- NCT07403617
- Testing
- VQDI-assisted target lung lobe selection strategy, Conventional target lung lobe selection strategy
- Where
- China
- Volunteers
- 285 people
- Sponsor
- China-Japan Friendship Hospital
Chronic Obstructive Pulmonary Disease
Inspiratory Muscle Training and Neuromuscular Electrical Stimulation in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a significant current public health problem, characterized by the presence of limited airflow.
- Trial name
- NCT04387318
- Testing
- Multimodal training, IMT + Pulmonary Rehabilitation, NMES + Pulmonary Rehabilitation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal de Santa Maria
COPD (With - Without Rehabilitation)
Effects of Structural Integration on Chest Wall Expansion Among COPD Patients
The present study aims to investigate the effects of the 10-Series of Structural Integration on chest wall expansion in patients with stable COPD using a randomized controlled trial design.
- Trial name
- NCT07752420
- Testing
- Structural Integration with Conventional Pulmonary Rehabilitation, Pulmonary Rehabilitation only
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Green International University
Non-cystic Fibrosis Bronchiectasis, Chronic Obstructive Pulmonary Disease
A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease
This study evaluates the safety, tolerability, and activity of inhaled GDC-6988 in participants with muco-obstructive disease.
- Trial name
- NCT06603246
- Testing
- GDC-6988
- Where
- 6 sites in United States
- Volunteers
- 17 people
- Sponsor
- Genentech, Inc.
Pulmonary Disease, Chronic Obstructive
Efficacy and Safety of Mepolizumab as an Add-on Treatment in Chronic Obstructive Pulmonary Disease (COPD)
This is a multi-centered, randomized, placebo-controlled, double-blind, parallel group, trial evaluating 2 doses of mepolizumab against placebo given every 4 weeks through subcutaneous (SC) injection.
- Trial name
- NCT02105961
- Testing
- Mepolizumab
- Where
- 169 sites in United States, Argentina and 13 more
- Volunteers
- 674 people
- Sponsor
- GlaxoSmithKline
COPD
Efficacy of AZD3199 in Chronic Obstructive Pulmonary Disease (COPD) Patients
The purpose of this study is to investigate the efficacy, safety and tolerability of 4 weeks treatment with AZD3199 in moderate to severe COPD.
- Trial name
- GLAD (NCT00929708)
- Testing
- AZD3199, formoterol
- Where
- 38 sites in Bulgaria, Canada and 3 more
- Volunteers
- 329 people
- Sponsor
- AstraZeneca
COPD
Estimation of the VQ11 Auto-questionnaire, to Follow Patients With Chronic Obstructive Pulmonary Disease
The purpose of this study is to estimate the capacity of the auto-questionnaire of quality of life, VQ11, to follow the evolution of patients with COPD (Chronic obstructive pulmonary disease) in stable state (without exacerbation…
- Trial name
- EPIC (NCT01651676)
- Testing
- VQ11 validation
- Where
- 17 sites in France
- Volunteers
- 57 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Chronic Obstructive Pulmonary Disease
A Study on the Heat Transport Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With Stable Angina Pectoris
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04046640
- Testing
- Infrared thermal imaging
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhejiang Chinese Medical University
Respiratory Disease, Asthma
A System to Classify Treatable Traits in Primary Care
This study proposes an approach to address an urgent unmet need in clinical practice, namely a pragmatic method of establishing what is the cause of a patient's complaint and the next steps to address this problem.
- Conditions
- Respiratory Disease, Asthma, Copd
- Trial name
- SMART (NCT05357274)
- Testing
- Diagnostic testing
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- Royal College of Surgeons, Ireland
Copd
Impact of Inhaled PT003 on Complexity and Variability of Tidal Breathing and Oscillatory Mechanics in Stable COPD Patient
Prospective, single-arm, open label, multicentre, phase II pilot study to evaluate the immediate and short term (one month) impact of a new long acting double bronchodilator on innovative parameters in stable and moderate to…
- Trial name
- OSCIVARI (NCT04087590)
- Testing
- Formoterol-glycopyrronium co suspension (PT003)
- Where
- France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Lille
Chronic Obstructive Pulmonary Disease, COPD
Predictors of Acute Exacerbation in Patients With COPD - an Observational Study
Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by respiratory problems and poor airflow with dyspnea and cough being the main symptoms.
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, COPD Exacerbation, COPD Exacerbation Acute
- Trial name
- PACE (NCT04140097)
- Testing
- Prospective monitoring of a large variety of parameters
- Where
- Germany
- Volunteers
- 355 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Cardiovascular Diseases, Pulmonary Disease
Improving Physical Activity in Rehabilitation
Cardiac rehabilitation is a programme of exercise and health advice for people recovering from heart disease. Pulmonary rehabilitation is a similar programme for people with chronic lung disease.
- Conditions
- Cardiovascular Diseases, Pulmonary Disease, Chronic Obstructive Pulmonary Disease
- Trial name
- IPAiR (NCT03264924)
- Testing
- IPAIR
- Where
- United Kingdom
- Volunteers
- 82 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Chronic Obstructive Pulmonary Disease
A 26-week Treatment Randomized, Double-blind, Double Dummy Study to Assess the Efficacy and Safety of QVA149
To demonstrate the non-inferiority of QVA149 110/50 µg o.d. to fluticasone/salmeterol 500/50 µg b.i.d. in terms of trough Forced Expiratory Volume in one second (FEV1) (mean of 23 hours 15 min and 23 hours 45 min post QVA149…
- Trial name
- NCT01709903
- Testing
- QVA149, Fluticasone/salmeterol
- Where
- 55 sites in Argentina, Chile and 2 more
- Volunteers
- 744 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease
Individualized Dosing Schedule of Inhaled Bronchodilator for Endotracheally Intubated COPD Patients
This study evaluates whether individualized dosing schedule of inhaled bronchodilator is more effective than fixed dosing in reducing airway resistance of intubated COPD patients.
- Trial name
- NCT01933984
- Testing
- Bronchodilators inhalation
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Shin-hwar Wu
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