Clinical trials: CORE
Acute Heart Failure
Acute Heart Failure - COngestion Repeated Evaluation (AHF-CORE)
The AHF-CORE study is a prospective, non-randomized, multicenter regional study. The main objective of the AHF-CORE study is to identify congestion markers (clinical, biological and ultrasound) at the beginning and at the end of…
- Trial name
- AHF-CORE (NCT03327532)
- Testing
- Clinical examination centered on congestion, Cardio-pulmonary and peritoneal ultrasound, Blood sample retrieved for biological assessment and biobanking
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Central Hospital, Nancy, France
Backache, Low
Core Muscle Stability on Low Back Pain and Quality of Life in Post- Menopausal Women
Low back pain, postural dysfunction, loss of balance control and stability are musculoskeletal changes that occur over life span due to aging process and are inevitable.
- Trial name
- NCT03902132
- Testing
- Core Stability exercises group, Traditional low back physical therapy group
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Plantar Fasciitis of Both Feet
Foot Core Stabilization Exercises Vs. Shockwave Therapy for Pain, Strength, and Function in Plantar Fasciitis
This study aims to evaluate the effectiveness and feasibility of two distinct approache extracorporeal shock wave therapy and foot core stabilization exercises in the treatment of plantar faciitis (PF) by comparing their impacts…
- Trial name
- NCT06890806
- Testing
- Foot Core Stabilization Exercise Group (FCSEG), Extracorporeal Shock Wave Therapy Group (ESWTG)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Neck Pain
Investigation of the Efficacy of Thoracic Mobilization Exercises Performed in Addition to Core Stabilization Exercises in Individuals With Chronic Non-Specific Neck Pain
Neck pain is one of the most common musculoskeletal complaints worldwide and is an important health problem that restricts the daily life activities of individuals.
- Trial name
- NCT06991140
- Testing
- Thorocal Mobilization Exercises, Core Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Ischemic Stroke
Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke
The purpose of the study is to understand whether a new treatment of stroke - endovascular clot removal - can be added to the current standard of care to improve patient outcomes.
- Trial name
- ESCAPE (NCT01778335)
- Testing
- Endovascular thrombectomy/thrombolysis
- Where
- Canada
- Volunteers
- 316 people
- Sponsor
- University of Calgary
Asthma
The Effects of Core Stabilization Training Among Patients With Asthma: A Randomized Controlled Trial
Objective: To investigate the effectiveness of core stabilization exercises combined with the patient education program (AEP) and breathing exercises in patients with asthma.
- Trial name
- NCT03335891
- Testing
- Core Stabilization Exercises, Control
- Volunteers
- 51 people
- Sponsor
- Yeditepe University
Amphetamine Use Disorders
Closed-loop tACS Modulation for the Core Clinical Features of Drug Addiction
Using specific EEG biomarkers in methamphetamine-dependent individuals, this study systematically probes the effect of closed-loop tACS based on brain states
- Trial name
- NCT06454474
- Testing
- Closed-loop tACS stimulation based on addiction-induced states
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Shanghai Mental Health Center
Inspiratory Muscle Training
Inspiratory Muscle Training in American Football Players
The aim of the randomized controlled study is to investigate the effects of high-intensity inspiratory muscle training on respiratory strength, balance, and core endurance in American Football (Tackle Football) athletes.
- Trial name
- NCT07246655
- Testing
- High-Intensity Inspiratory Muscle Training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Non Specific Low Back Pain
Comparative Effect of Virtual Reality and Core Stability Exercises in Patients With Non-specific Chronic Low Back Pain
Non-specific low back pain (NSLBP) is a prevalent musculoskeletal disorder. (Maher et al., 2017). Globally, 60%-80% of adults' experience low back pain, with 10% developing chronic forms, of which 85% are classified as chronic…
- Trial name
- core stability (NCT07602816)
- Testing
- group A, Group B, Group C
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Emad Eldin Mohamed
Gout
A Study of the Efficacy of Canakinumab in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy (Core Study) and a Long-term Study of the Efficacy and Safety of Canakinumab in Patients With Gout (Extension Study)
The 24-week, dose-ranging, multi-center, double-blind, double-dummy, active-controlled core study investigated the prophylactic effect of canakinumab on the signs and symptoms of acute flares in chronic gout patients initiating…
- Trial name
- NCT00819585
- Testing
- Canakinumab, Colchicine, Allopurinol
- Where
- 89 sites in United States, Argentina and 16 more
- Volunteers
- 432 people
- Sponsor
- Novartis Pharmaceuticals
Sacroiliac Joint Dysfunction
Comparison of Core Stability and Hip Strengthening Protocols in Sacroiliac Joint Dysfunction
The aim of this research is to compare the effects of core stability exercises and hip strengthening exercises on pain, posture, balance, proprioception, and functional status in patients with sacroiliac joint dysfunction.
- Trial name
- NCT07716215
- Testing
- Core Stabilization, Hip Strengthening Exercises
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Parkinson's Disease
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD)
The purpose of this study is to investigate genetic and environmental risk factors that increase susceptibility to the development of early-onset Parkinson's disease (developed at or before age 50).
- Trial name
- NCT00104585
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Columbia University
Core Competency, Reflective Thinking
A Mixed-Methods Analysis of the Six Core Competencies and AI Literacy Reflected in Medical Students' Self-Assessment During Small-Group Discussions
This study aims to examine how the six Accreditation Council for Graduate Medical Education (ACGME) core competencies and AI literacy are reflected in medical students' self-assessment narratives following small-group…
- Trial name
- NCT07775885
- Where
- Taiwan
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Chronic Low Back Pain
Home-Based Rehabilitation Training for Chronic Low Back Pain Patients
The goal of this clinical trial is to test the effectiveness of a new digital therapy for managing chronic low back pain in adults.
- Trial name
- NCT05998434
- Testing
- Improving Low Back Pain Through Motor Control Training
- Volunteers
- 104 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Pelvic Floor, Functional Constipation
The Effect of Pelvic Floor Muscle Training in Functional Constipation
The aim of this study is to examine the effect of individualized pelvic floor muscle training on symptoms, core muscle function, and quality of life in patients with functional constipation.The research is being conducted at the…
- Conditions
- Pelvic Floor, Functional Constipation, Biofeedback, Chronic Constipation
- Trial name
- NCT07603414
- Testing
- Lifestyle change training, Diaphragmatic Breathing Exercise, Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Selin Koşan
Parkinson Disease, Pilates
Effect of Pilates Application on Abdominal Muscle Function, Core Stability, Musculoskeletal Pain, Quality of Life, Anxiety and Depression in Parkinson's Patients
In this study, it is aimed to investigate the effect of Pilates application on abdominal muscle function, core stability, musculoskeletal pain, quality of life, anxiety and depression in Parkinson's Patients.
- Conditions
- Parkinson Disease, Pilates, Muscle Function
- Trial name
- NCT04619784
- Testing
- Pilates Exercises, control
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Dokuz Eylul University
Breast Cancer
Chemoprevention Therapy Plus Surgery in Treating Women With Breast Cancer
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of fenretinide and tamoxifen before surgery may be an effective way to prevent the recurrence of or…
- Trial name
- NCT00003099
- Testing
- Fenretinide, Tamoxifen Citrate
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- M.D. Anderson Cancer Center
Healthy
Evaluation of Injury Profile, Core Stability and Balance in Female Hip-Hop Dancers
The objectives of the study are to evaluate core stability and static and dynamic balance performance in adult female hip-hop dancers and compare these scores with those of healthy non-dancer females; to obtain the injury history…
- Trial name
- NCT06528652
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ege University
Body Temperature Regulation
Non-invasive Sensor for Core Temperature Measurement
Soldiers are required to perform and maintain alertness in difficult environmental conditions. The sensor examined in this trail may indicate body core temperature elevation during exertion.
- Trial name
- Drager (NCT02017184)
- Testing
- Noninvasive core temperature thermistor
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Spinal Cord Injury
Wheelchair Indoors Curling With SCI patients_RCT
This study investigates if, patients with diagnosed chronic spinal cord injury will benefit from an Indoor Curling Exercise program on their control capabilities of trunk movements and on their intrinsic motivation for physical…
- Trial name
- SCI-RCT (NCT02550834)
- Testing
- Wheelchair indoors curling training
- Where
- 2 sites in Switzerland
- Volunteers
- 32 people
- Sponsor
- HES-SO Valais-Wallis
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