Clinical trials: CORE
Diplegia
Scooter Board Activities in Diplegic Cerebral Palsy
Children with CP may have muscle weakness, changes in mobility, posture, muscle tone, motor coordination and deficits in postural control. These changes, individually or collectively, affect psychomotor function.
- Trial name
- NCT05609422
- Testing
- Physical therapy program, scooter board activities
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Badr University
Alzheimer Disease
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic amyloid deposition using the PET tracer [C-11]PiB in participants in the UAB Alzheimer's Disease Center cohort.
- Trial name
- PiB ADC (NCT03503331)
- Testing
- [C-11]PiB-PET/MRI
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hand Functions on Hemiplegic Cerebral Palsy
Effect of Action Observation Training Versus Core Stability Training on Hand Functions in Children With Hemiplegic Cerebral Palsy
This study will be conducted to compare between the effectiveness of Action observation therapy (AOT) and core stability training and the combination of Action observation therapy (AOT) and core stability training on hand…
- Trial name
- NCT06930053
- Testing
- Core stability training, Action observation therapy, combination of Action observation therapy and core stability training .
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Kafrelsheikh University
Breast Cancer, Breast Neoplasms
Integrated Patient Avatars for Guiding Systemic Therapy Treatments in Metastatic Breast Cancer Patients
The investigators propose to use clinically validated patient avatar technology ("PDXovo") that can test multiple drugs against patients' cancers to identify the most promising systemic therapy for each individual.
- Conditions
- Breast Cancer, Breast Neoplasms, Metastatic Breast Cancer, Cancer, Breast
- Trial name
- NCT04608357
- Testing
- Needle Core Biopsies
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Sunnybrook Health Sciences Centre
Core Stability
Chronic Effect of Individualized Core Stability Programs in Recreational Athletes.
Core stability (CS) training is nowadays largely used in several fields, mainly to enhance athletic performance and to prevent and rehabilitate musculoskeletal injuries.
- Trial name
- NCT03459430
- Testing
- Core stability training
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CASTO JUAN RECIO
Cardiac Rehabilitation, Motivational Interviewing
Motivational Interviewing & Clinician Centered Interviewing on Cardiac Rehab
The purpose of this project is to examine the differences in outpatient cardiac rehab (OPCR) core component outcomes on different intervention conditions.
- Trial name
- MIOPCR (NCT04899752)
- Testing
- Motivational Interviewing
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Auburn University
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Dynamic Q Angle and Core Endurance in Adolescent Athletes With Patellofemoral Pain Syndrome
This observational, cross-sectional study aimed to compare dynamic Q-angle, trunk/core endurance, and lower-extremity flexibility between elite adolescent female and male sprinters with and without patellofemoral pain syndrome…
- Trial name
- PFPS-QCORE (NCT07328750)
- Testing
- Patellofemoral Pain Syndrome Status
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Stroke
Intravenous Thrombolysis With Tenecteplase Plus Thrombectomy Versus Thrombectomy Alone In Patients With A Large Ischemic Stroke: A Multicenter Randomized Controlled Trial (IVT-ALL-IN)
Stroke is a frequent and severe disease worldwide, representing the second leading cause of death and the leading cause of acquired disability.
- Trial name
- IVT-ALL-IN (NCT07603440)
- Testing
- Intravenous administration, MT alone
- Where
- 36 sites in France
- Volunteers
- 486 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sacroiliac Joint Pain
CMCT Versus CSE in Treatment of SIJ Pain
This study aims to investigate the difference between integrating lumbopelvic cognitive movement control training versus core stabilization exercises to the conventional physiotherapy program on pain, function, lumbopelvic…
- Trial name
- NCT07370272
- Testing
- The conventional Physiotherpay Program (US & MET), Core Stability Exercises (CSE), Lumbopelvic cognitive movement control training (CMCT)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Bone Marrow Biopsy Procedures
Powered Bone Marrow Aspiration and Core Biopsy System Compared to Manual Devices
This is a randomized study evaluating use of a powered bone marrow biopsy and aspiration system (OnControl by Vidacare) compared to traditional manual devices.
- Trial name
- NCT01312519
- Testing
- OnControl Bone Marrow Biopsy and Aspiration System, Manual bone marrow sampling device
- Where
- 2 sites in United States, Spain
- Volunteers
- 50 people
- Sponsor
- Vidacare Corporation
Athletic Performance
Effect of Instability Resistance Training on Balance, Core Muscle Strength, and Athletic Performance
The goal of this experimental study is to examine the effect of instability resistance training (IRT) on balance ability, core muscle strength, and athletic performance of young Chinese male kayak canoeists.
- Trial name
- NCT06432595
- Testing
- Instability resistance training and Traditional resistance training
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Ankle Sprains, Ankle Injuries
Effect of Chronic Ankle Instability on Core Stabilization, Dynamic Balance and Agility
Ankle sprains are the most common injury in basketball, especially involving repetitive maneuvers such as acceleration, deceleration, jumping, and landing.
- Conditions
- Ankle Sprains, Ankle Injuries, Chronic Ankle Instability
- Trial name
- NCT05441319
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Surgery
Efficacy of Warming Device During Surgery
This study will test the hypothesis that an electric heating device, the Hot Dog warming system is as effective as the Bair Hugger forced air heating system.
- Trial name
- NCT00715728
- Testing
- Intraoperative warming with Bair Hugger forced air system, Intraoperative warming with Hotdog resistive heating system
- Where
- Austria
- Volunteers
- 28 people
- Sponsor
- The Cleveland Clinic
Mood Disorders
Virtual Reality VAlidation Tool for Cognitive Rehabilitation, Oriented Project for People With Psychosocial Disabilieties
Randomized controlled open-label cross-over clinical feasibility study with waiting list, 60 people will be recruited from the Consultation and Psychosomatic Psychiatry Center of the University Hospital of Cagliari (San Giovanni…
- Trial name
- NCT05070065
- Testing
- Cognitive remedy intervention with virtual reality (CEREBRUM)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Cagliari
Covert Cerebrovascular Disease
Reducing Risk of Stroke and DementIa In patientS With COVert cERebrovascular Disease
The purpose of the DISCOVER study is to pilot acceptable approaches to people with covert cerebrovascular disease (CCD) and their follow-up.
- Trial name
- DISCOVER (NCT06878430)
- Testing
- Functional and Cognitive scores
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Pain
A Study to Investigate Delayed-release Tablets
This is a single-centre, open-label, non-randomised, two-arm study in 12 healthy male volunteers. This study is designed to correlate the gastrointestinal transit behaviour of delayed-release diclofenac potassium tablets with…
- Trial name
- NCT02004301
- Testing
- Radiolabelled T4 Tablet, Radiolabelled T6 Tablet
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BDD Pharma Ltd
Interprofessional Approach, Ultrasound
Interprofessional Approach to Ultrasound Diagnosis and Intervention in Critical Care Patients With Pneumothorax and/or Hemothorax
Investigate the efficacy of interprofessional team approach to ultrasound guided diagnosis and intervention (pigtail or chest tube insertion) in critical care patients with Pneumothorax and/or hemothorax.
- Conditions
- Interprofessional Approach, Ultrasound, Intervention, Critical Care
- Trial name
- NCT06825299
- Testing
- Chest-Tube Insertion
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Acute Myeloid Leukemia
Dasatinib in Combination With Chemotherapy for Relapsed or Refractory Core Binding Factor Acute Myeloid Leukemia
This study will examine the appropriate dose and side effects of dasatinib, when it is given with the standard of care chemotherapy for children and adolescents with Acute Myeloid Leukemia (AML).
- Trial name
- NCT02680951
- Testing
- Dasatinib, Fludarabine, Cytarabine
- Sponsor
- Emory University
Hypothermia
Impact of Prewarming on Perioperative Body Core Temperature and the Outcomes of Cytoreductive- and Major Open Abdominal Surgery: A Randomised Trial
The primary purpose of this study is to determine whether a prewarming period of at least 30 minutes during induction of general and combined epidural anesthesia reduces the core temperature drop normally occuring in patients…
- Trial name
- PREWARM (NCT02364219)
- Testing
- Prewarming, Microdialysis
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Charite University, Berlin, Germany
Scoliosis Idiopathic Adolescent
Effect of a 16-Week Physiotherapeutic Corrective Exercise Program on Spinal Deformities in Adolescent Idiopathic Scoliosis
Brief Summary Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that may progress during adolescence and lead to postural asymmetry, spinal rotation, pelvic imbalance, reduced spinal mobility, and…
- Trial name
- SPINE-AIS16 (NCT07736456)
- Testing
- Structured Physiotherapeutic Corrective Exercise Program, Standard Physiotherapy Exercise Program
- Where
- Kosovo
- Volunteers
- 68 people
- Sponsor
- Alma Mater Europaea - Slovenia
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