Clinical trials: CORE
Cesarean Section
Determination of Core Body Temperature in Parturient Warmed With Upper or Underbody Forced Air Cover (Bair Hugger)
This study is intended to calculate the core body temperature in patients who are having a Cesarean Section (C/S) and are kept warm with an Upper Body Forced Air Warming device (Bair Hugger) or underbody forced air warmer.
- Trial name
- NCT05314075
- Testing
- Upper Body Forced Air Warming device, Under Body Forced Air Warming device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Virginia Commonwealth University
Low Back Pain
ELDOA Technique Versus Lumbar SNAGS With Motor Control Exercises
Study will be a Randomized clinical trial to check the effects of ELDOA technique versus lumbar SNAGS with motor control exercises on pain, function and mobility in patients with chronic low back pain.
- Trial name
- NCT06049251
- Testing
- ELDOA exercises, Lumbar SNAGS and motor control exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Temporomandibular Joint Disorders, Core Stability
Temporomandibular Joint Problems and Core Stabilization
This study aimed to investigate the relationship between temporomandibular joint problems, head posture, tongue strength, and endurance with core stabilization.
- Trial name
- NCT06034756
- Testing
- TMJ dysfunction, Maximum pain-free mouth opening (MMO), Forward head posture
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Healthy Volunteers
A Phase 1a Trial Assessing the Safety, Tolerability, and Immunogenicity of GS-4774 (GI-13020) at Various Dose Levels and Regimens in Healthy Adults
This trial will be test the safety, tolerability, and immunogenicity of GS-4774 (GI-13020) in various doses and dosing regimens in healthy adults at one center in the US.
- Trial name
- NCT01779505
- Testing
- GS-4774
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Tuberculosis, Diagnoses Disease
TB-CAPT CORE Truenat Trial
A cluster randomized controlled trial to evaluate the effect of placing Truenat platform/TB assays at primary health care clinics combined with rapid communication of results on time to treatment initiation of microbiologically…
- Trial name
- NCT04568954
- Testing
- Truenat TB platform/TB assays
- Where
- 4 sites in Mozambique, Tanzania
- Volunteers
- 3,987 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Runner's Knee
McGill Core and Proprioception Training in Runner's Knee.
Runner's knee, most common condition causing knee pain; is defined by pain around or behind patella in young and physically active individuals. Runner's knee affects 25 to 40% knee patients reported in sports clinic.
- Trial name
- NCT07909694
- Testing
- McGill Core stability exercises, Proprioception Training
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- University of Management and Technology Lahore
Hiv
A Phase 1 Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core)
A Phase 1, Randomized, First-in-human, Open-label Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core) in HIV-1 Uninfected Adults in Good…
- Trial name
- NCT05001373
- Testing
- Core-g28v2 60mer mRNA Vaccine, eOD-GT8 60mer mRNA Vaccine
- Where
- 4 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
Healthy, Sport
Static vs Dynamic Core Exercises for Improving Serve and Spike Speed in Elite Young Male Volleyball Players
Volleyball performance at the elite level will depend heavily on the speed and efficiency of overhead actions, particularly the serve and the spike.
- Trial name
- CORE-VOLLEY (NCT07641439)
- Testing
- Static Core Exercise Training, Dynamic Core Exercise Group (DCEG), Velocity Speed Gun
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Hypermobility, Joint, Muscle Weakness
"Core" Muscle Endurance, Upper Extremity Muscle Strength, Grip Strength, and Hand-eye Coordination in Generalized Joint Hypermobility
Every individual with joint hypermobility may not apply to a health institution because they do not have a complaint that will affect their daily life.
- Conditions
- Hypermobility, Joint, Muscle Weakness, Coordination Lack
- Trial name
- NCT05896722
- Testing
- Core muscle endurance, Upper extremity muscle strength, Grip strength
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Body Temperature Changes, Anesthesia
Core Temperature Variations During Midazolam vs Propofol Sedation for Neuraxial Anesthesia
The present study is a pilot study aiming to compare the variation in core temperature (measured through the non-invasive device Spot-OnTM3MTM) in patients submitted to neuraxial anesthesia for orthopedic procedures, during…
- Trial name
- NCT02502877
- Testing
- Midazolam, Propofol, Standard
- Where
- Portugal
- Volunteers
- 27 people
- Sponsor
- Hospital da Luz, Portugal
Neck Pain
Diaphragmatic Doming vs Breathing Exercises on Ventilatory Function & Core Endurance in Chronic Neck Pain
The purpose of the study is to investigate if there is any difference between effect of diaphragmatic doming versus breathing exercises on ventilatory function and core endurance in patients with chronic neck pain
- Trial name
- NCT06119399
- Testing
- Diaphragmatic Breathing Exercise, Pursed Lip Breathing Exercise, Doming of the diaphragm
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Mina Atef Georgui Elias
Healthy Lifestyle, Health Behavior
Effects of Online Pilates and Face-To-Face Pilates on Healthy Individuals
Many studies on pilates have shown that these exercises positively affect the endurance of core muscles, mental health, and quality of life in healthy individuals when applied face-to-face.
- Trial name
- COVID (NCT05309486)
- Testing
- Online and Face-to-face Pilates trainings
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Temperature Change, Body, Anesthesia
Correlation Between Core Temperature and Skin Temperature in Pediatrics
During general anesthesia, temperature monitoring is critical especially in pediatrics. Recently developed 3M™ Bair Hugger™ skin temperature which is applied on temporal artery is correlated with core temperature measure by…
- Conditions
- Temperature Change, Body, Anesthesia, Children, Only
- Trial name
- temperature (NCT04057612)
- Testing
- Esophagus temperature monitoring, Carotid artery temperature monitoring
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Ajou University School of Medicine
Systemic Sclerosis (SSc), ANCA Associated Vasculitis (AAV)
Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases
This study is a single-center, open-label, single-arm, dose-escalation trial. The aim of this study is to investigate the safety and efficacy of Anti-CD19 IL-10/IL15 CAR-NK cells in patients with refractory/relapsed autoimmune…
- Conditions
- Systemic Sclerosis (SSc), ANCA Associated Vasculitis (AAV), Idiopathic Inflammatory Myopathy (IIM), Sjogren's Syndrome
- Trial name
- NCT06614270
- Testing
- Anti-CD19 IL-10/IL15 CAR-NK
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cystic Fibrosis
A Single Arm 48-Week Follow-on Safety Study to a Core Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI®
This is a 48-week extension study to CMA-0631-PR-0010 Core Study. Patients who have a positive culture for P. aeruginosa at visit 4 of the first 8-week core study period and/or if deemed appropriate by the Investigators will be…
- Trial name
- CT03Ext (NCT01111383)
- Testing
- tobramycin
- Where
- 20 sites in France, Poland and 1 more
- Volunteers
- 209 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Post and Core Failure
Clinical Comparison of Endodontically Treated Teeth Restored With Fiber Posts or Cast Metal Posts
There are few randomized controlled trials comparing intraradicular posts used to restore endodontically treated teeth, especially considering cast posts and glass fiber posts.
- Trial name
- NCT01461239
- Testing
- fiber post and resin core - self-adhesive cement, cast post and core, fiber post luted with conventional resin cement
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Anterior Cruciate Ligament Reconstruction Rehabilitation
Effects of Core Exercises on Balance in People With and Without ACL Surgery
The main purpose of this study is to evaluate and compare the effects of an 8-week core stabilization exercise program on balance, trunk muscle endurance, and lower body strength.
- Trial name
- NCT07328139
- Testing
- Core Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biruni University
Adolescent
The Effect of Motor Imagery Training in Addition to Core Stabilization Exercises on Core Performance, Balance, Functional Capacity, and Quality of Life in Healthy Adolescents Girls
Adolescence is the period in which a person grows and develops the fastest, covering the transition from childhood to maturity. Compared to sedentary adolescents who regularly exercise, there were significant differences in…
- Trial name
- NCT05986175
- Testing
- Motor Imagery Training, Core Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Biruni University
Injury of Body Region, Performance Enhancement
Multicomponent Exercise Program Effects on Performance and Injury Reduction in Recreational Runners
Study aim was to evaluate effectiveness of two home-based exercise programs upon athletic performance, physical parameters and injury reduction in recreational runners.
- Conditions
- Injury of Body Region, Performance Enhancement, Aerobic Fitness (VO2max), Muscle Strength Development
- Trial name
- NCT07741539
- Testing
- Multicomponent Exercise Program, Traditional Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Frailty, Cancer
ReVital-CORE Program
Pilot feasibility study of the ReVital Chemotherapy Online Resiliency Evaluation (CORE) program. As part of standard of care, patients starting a new chemotherapy regimen are referred to complete a pre-chemotherapy cancer…
- Conditions
- Frailty, Cancer, Chemotherapy-Induced Change
- Trial name
- ReVital-CORE (NCT04852575)
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Kessler Foundation
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