Clinical trials: CORE
Healthy Children
Fine Motor Performance in School-aged Children
The goal of this observational cross-sectional study is to investigate the relationship between core stability, hand grip strength, and handwriting performance in typically developing school-aged children aged 8 to 12 years.
- Trial name
- HGS/HLS (NCT07767656)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Lymphocytic Leukemia (CLL)
A Study Evaluating the Impact of Venetoclax on the Quality of Life for Subjects With Relapsed (Your Cancer Has Come Back) or Refractory (no Response to Previous Cancer Treatments) Chronic Lymphocytic Leukemia (CLL) While Receiving Venetoclax Monotherapy (a Single Agent).
The purpose of this open-label, single-arm study was to evaluate the impact of venetoclax on the quality of life of participants including those with with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL; a type of…
- Trial name
- VENICE II (NCT02980731)
- Testing
- Venetoclax
- Where
- 33 sites in Argentina, Australia and 8 more
- Volunteers
- 210 people
- Sponsor
- AbbVie
Breast Cancer
Accuracy of VABB Elite 10G Versus BARD 14G CNB
In this study, patients whose breast ultrasound showed a space-occupying lesion and needed biopsy to clarify the pathology were selected as the research subjects.
- Trial name
- NCT04612439
- Testing
- VABB Elite 10G, BARD 14G CNB
- Where
- China
- Volunteers
- 1,470 people, healthy volunteers welcome
- Sponsor
- Fudan University
Vitamin D Absorption
Effect of Core Stability Exercise Versus Whole Body Vibration in Improving Vitamin D Absorption in Women
This study was conducted to explore the influence of core stability exercise versus whole body vibration in improving vitamin D absorption in women.
- Trial name
- NCT06721637
- Testing
- Group A (n = 20): received core stability exercise trained three times a week for 8 weeks., Group B (n = 20): received whole body vibration trained three times a week for 8 weeks
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- October 6 University
Bladder Urothelial Carcinoma
Ultrasound-Guided Core Needle Biopsy to Stage Urothelial Carcinoma of the Bladder (US UCB)
This study is being done to test the feasibility and accuracy of using an ultrasound-guided core needle biopsy technique as a potential tool for staging urothelial carcinoma of the bladder (UCB).
- Trial name
- NCT07029256
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Chondromalacia Patellae
Temporal Activation of Core Muscles and Vasti in Isolated Patellofemoral Osteoarthritis
Objective: To compare the temporal muscle activation between females with PF OA and normal controls during stair ascent. Methods: An observational comparative study was conducted with thirty-one females with PF OA and 11 healthy…
- Trial name
- NCT04589702
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Axial Spondyloarthritis, Telerehabilitation
Comparison of Tele-rehabilitation or Video-Based Core Exercises in Individuals With Axial Spondyloarthritis
Exercise is a core treatment method in the management of Axial Spondyloarthritis. Clinical guidelines recommend a combination of pharmacologic and non-pharmacologic approaches to reduce disease activity and symptoms and improve…
- Conditions
- Axial Spondyloarthritis, Telerehabilitation, Exercise
- Trial name
- NCT06000072
- Testing
- Core Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Acibadem University
Ankylosing Spondylitis
The Effects of Clinical Pilates Training in Patients With Ankylosing Spondylitis
The objective of this study was to examine the effects of 8-week clinical Pilates training on disease-specific indices, core stability, and balance in ankylosing spondylitis (AS) patients.
- Trial name
- NCT04292028
- Testing
- Pilates, Home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dokuz Eylul University
Multiple Sclerosis
Rex Robot Assisted Rehabilitation to Enhance Balance and Mobility for People With Multiple Sclerosis, Clinical and Biomarker Study - RAPPER IV
Multiple Sclerosis (MS) poses challenges to balance and mobility, impacting the daily lives of affected individuals. The RAPPER IV study is a clinical trial to evaluate a balance and mobility training intervention supported by a…
- Trial name
- RAPPER IV (NCT06429085)
- Testing
- Rex robotic assisted balance exercises
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Lupus Nephritis
Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension)
The purpose of this up to 6-year extension study is the evaluation of the efficacy and safety 1. after study treatment withdrawal in patients with lupus nephritis (LN) who achieved response (complete renal response [CRR] or…
- Trial name
- SIRIUS-LN ext (NCT06711887)
- Testing
- Ianalumab
- Where
- 51 sites in United States, Brazil and 16 more
- Volunteers
- 348 people
- Sponsor
- Novartis Pharmaceuticals
Postural Balance, Core Strength
Core Strength and Coordinative Skills
Evaluation of healthy young adults regarding balance, core strength/core stability and physical fitness. Correlation of primary outcome parameters and selected secondary parameters.
- Conditions
- Postural Balance, Core Strength, Core Stability, Physical Fitness
- Trial name
- NCT05719532
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johannes Kepler University of Linz
Breast Cancer
Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy
The objective of the proposed research is to develop new diagnostic modalities based on optical spectroscopy (auto fluorescence, absorption, and scattering) for the diagnosis of breast cancer and test its performance as an…
- Trial name
- NCT00734838
- Testing
- High Resolution Microendoscope
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Duke University
Urinary Incontinence
Core Muscle Strength, Endurance, and Balance in Women With Urinary Incontinence
Urinary incontinence (UI) is defined as the involuntary loss of urine that occurs outside the individual's control and negatively affects both hygiene and social life.
- Trial name
- NCT07127549
- Testing
- Muscle strength, endurance and balance assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Seda Saka
Hemiplegic Cerebral Palsy, Cerebral Palsy (CP)
Effects of Fun-Core (Child-Friendly Core Stabilization) Exercises on Balance and Functional Mobility in Children With Spastic Cerebral Palsy
A total of 54 children, aged between 6 and 12 years, diagnosed with hemiplegic cerebral palsy and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical Medicine and…
- Conditions
- Hemiplegic Cerebral Palsy, Cerebral Palsy (CP), Core Stabilization, Exercise
- Trial name
- NCT07233824
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University
Hallux Valgus
Improving the Function of the Foot by Core Foot System (CFS) Exercise Theory in Patients After Hallux Valgus Surgical Procedure
The aim of the study is to identify the impact of CFS foot muscle training on time-space parameters, anthropometric parameters and bioelectrical activity (EMG) of the foot muscles during walking and to develop an algorithm for an…
- Trial name
- NCT05210127
- Testing
- Scarf osteotomy for Hallux Valgus deformity
- Volunteers
- 60 people
- Sponsor
- Józef Piłsudski University of Physical Education
Acute Myeloid Leukemia, Core-Binding Factor
Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AML
The purpose of the study is to determine whether Fludarabine in combination with cytarabine is more effective than high-dose cytarabine in post-remission therapy for patients with core-binding factor acute myeloid leukemia
- Trial name
- NCT02926586
- Testing
- Fludarabine, Cytarabine
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques
Ticin Pilot Study: Sirolimus-Eluting Balloon for Stabilization and Regression of Non-Obstructive Coronary Plaques.
The goal of this pilot clinical trial is to evaluate the use of the Selution SLR sirolimus-eluting balloon, in addition to guideline-directed medical therapy (GDMT), for the preventive treatment of non-flow-limiting vulnerable…
- Conditions
- Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques, Multivessel Coronary Artery Disease, Coronary Vessel
- Trial name
- NCT06928883
- Testing
- Sirolimus drug eluting ballooon therapy, Optimal guidelines-directed medical therapies (GDMT)
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Cardiocentro Ticino
Rotator Cuff Tear
Surgical Safety and Effectiveness in Orthopedics: Swiss-wide Multicenter Evaluation and Prediction of Core Outcomes in Arthroscopic Rotator Cuff Reconstruction
Surgical safety and effectiveness in orthopedics: Swiss-wide multicenter evaluation and prediction of core outcomes in arthroscopic rotator cuff reconstruction.
- Trial name
- ARCR_Pred (NCT04321005)
- Testing
- arthroscopic rotator cuff reconstruction
- Where
- 20 sites in Germany, Switzerland
- Volunteers
- 973 people
- Sponsor
- University Hospital, Basel, Switzerland
Temporomandibular Joint Dysfunction, TMD
Effects of Core Strengthening Exercises for Treating TMD
Temporomandibular disorders (TMD) are commonly managed with non-invasive interventions such as manual therapy, therapeutic exercise, relaxation techniques, and patient education.
- Conditions
- Temporomandibular Joint Dysfunction, TMD, TMJ Internal Derangement, Myofascial Pain
- Trial name
- NCT07226505
- Testing
- Experimental: Group 1: Core Strengthening, Group 2: Standard TMD PT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loyola University
Septic Shock, Sepsis
Core-to-Big-Toe Temperature Gradient as a Marker of Peripheral Perfusion in Adult Patients With Septic Shock
Septic shock is a life-threatening condition caused by severe infection that leads to dangerously low blood pressure and impaired blood flow to body tissues and organs.
- Trial name
- NCT07871305
- Volunteers
- 54 people
- Sponsor
- Assiut University
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