Clinical trials: CORE
Chronic Hepatitis B
NASVAC Phase-III Trial in Chronic Hepatitis B (CHB) Patients
The general objective of the present clinical trial is to compare the therapeutic efficacy of a combination therapeutic vaccine containing hepatitis B surface antigen (HBsAg) and hepatitis B core antigen (HBcAg) [later called…
- Trial name
- NASVAC (NCT01374308)
- Testing
- NASVAC, Pegylated interferon alpha 2b
- Where
- Bangladesh
- Volunteers
- 160 people
- Sponsor
- Clinical Research Organization, Dhaka, Bangladesh
Low Back Pain
Office Program Effects on Pain, Posture, Muscle Physiology, Stress, Ergonomics, and Quality of Life in LBP Workers
This interventional study aims to evaluate the effectiveness of an office worker's program in reducing low back pain and improving physical and psychosocial outcomes among office employees.
- Trial name
- NCT07250568
- Testing
- Exercise, Education, Advice
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Suci Wahyu Ismiyasa
Hypothermia; Anesthesia, Hypothermia Following Anesthesia
Can the SpotOn™ Zero-Heat-Flux-Thermometry Sensor Accurately Measure Core Temperature in Children?
The present study aims to assess the accuracy of the SpotOn™ Zero-heat-flux-thermometry sensor in measuring core temperature in the paediatric population in the perioperative period.
- Conditions
- Hypothermia; Anesthesia, Hypothermia Following Anesthesia, Children
- Trial name
- NCT03157609
- Testing
- Thermometry
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universitair Ziekenhuis Brussel
Autonomic Dysfunction, Orthostatic Intolerance
Continuous and Non-invasive Measurements by Task Force® CORE/CARDIO in Autonomic Function Testing (AFT)
Background: The investigational device, "Task Force® CORE" (TFC, CNSystems Medizintechnik GmbH, Graz, Austria) together with the "Task Force® CARDIO" (TFCARDIO, CNSystems Medizintechnik GmbH, Graz, Austria) medical device…
- Trial name
- NCT05977335
- Testing
- Autonomic Function Testing
- Volunteers
- 75 people
- Sponsor
- CNSystems Medizintechnik GmbH
Colorectal Cancer
Core Stability Program in Colorectal Cancer Survivors
The purpose of this study is to determine the effects of physical training program to improve deep stabilizer muscle in colorectal cancer survivors
- Trial name
- NCT02052050
- Testing
- core stability
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Postoperative Hypothermia, Thermal Comfort
The Effects of Active Warming on Temperature on Core Body and Thermal Comfort
Purpose: This study was conducted to examine the effect of warmed intravenous fluids (WIVF) on the core body temperature and the patients' thermal comforts during the postoperative period in patients undergoing transurethral…
- Conditions
- Postoperative Hypothermia, Thermal Comfort, Body Temperature Changes
- Trial name
- NCT04985617
- Testing
- Warmed Fluids
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Ege University
Chronic Hepatitis B
A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Negative Chronic Hepatitis B
This primary objectives of this study are to compare the efficacy, safety, and tolerability of tenofovir disoproxil fumarate (TDF) versus adefovir dipivoxil (ADV) for the treatment of pre-core mutant chronic hepatitis B.
- Trial name
- NCT00117676
- Testing
- TDF, ADV, FTC/TDF
- Where
- 80 sites in United States, Australia and 13 more
- Volunteers
- 382 people
- Sponsor
- Gilead Sciences
Diaphragm; Relaxation
The Influence of the Diaphragm Muscle and Pain Perception on Lower Limb Neuromuscular Control in Sports Practice.
Core stability is maintained mainly by muscle function of abdominal and lumbar region, including the diaphragm muscle. It is known that exists a connection between trunk's muscle activity and the movement of lower limb and lower…
- Trial name
- NCT05982210
- Testing
- Breathing Exercises and Manual Therapy of the Muscle Diaphragm and Ribs Protocol
- Where
- Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Non Traumatic Osteonecrosis of the Femoral Head (Hip)
Controlled Study of Stage 3 Osteonecrosis Treatment by Bone Marrow
In stage 3 Osteonecrosis (ON) of the femoral head, a beneficial effect of bone marrow grafting was reported with a reduction of the functional evolution and the necessity of a total prosthesis placement in a non-controlled…
- Trial name
- NCT01544712
- Testing
- core decompression with autologous bone marrow implantation, core decompression of the femoral head
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege
Coronary Artery Disease
Screening For Asymptomatic Obstructive Coronary Artery Disease Among High-Risk Diabetic Patients Using CT Angiography, Following Core 64
Patients with a known history of diabetes mellitus and no prior documented evidence of cardiovascular disease will be evaluated for inclusion in the study.
- Trial name
- faCTor-64 (NCT00488033)
- Testing
- CT Angiography
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Intermountain Health Care, Inc.
Amputation
The Investigations of Core Muscles, Gait, Balance and Proprioception in Transtibial Amputees
The goal of this observational study is to investigate the effects of transtibial amputation on core function and endurance, and their relationship with proprioception, balance, and gait in adults with transtibial amputation and…
- Trial name
- NCT07203235
- Testing
- evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- sevilay seda bas
Cardiac Arrest, Postresuscitation Encephalopathy
Prehospital Non-invasive Cooling of Comatose Patients After Cardiac Arrest
Single centre randomized controlled two arm clinical trial of patients after out of hospital cardiac arrest with return of spontaneous circulation.
- Trial name
- NCT03829215
- Testing
- CAERVest cooling device
- Where
- Austria
- Sponsor
- Medical University of Vienna
Diastasis Recti
Efficiency of Abdominal Corset and Core Stabilization Exercises in the Treatment of Postpartum Diastasis Recti Abdominis
Participants will be randomly divided into three groups as core stabilization group, combination of core stabilization and corset group and only corset group.
- Trial name
- NCT05195463
- Testing
- Exercise intervention, Exercise intervention by wearing abdominal corset, Corset intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Medipol University Hospital
Attention-deficit/Hyperactivity Disorder
Attention-deficit/Hyperactivity Disorder Translational Center for Identifying Biomarkers
The purpose of this study was to identify genetic, brain morphologic, and environmental biomarkers that contribute to the pathophysiology of attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT02623114
- Testing
- methylphenidate, atomoxetine
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Seoul National University Childrens Hospital
Core Body Temperature
Pill Study Hyperthermia Device (Heckel HT 3000): Monitoring Core Body Temperature Using Wireless Technology
The primary objective of the proposed study is to determine the use of a wireless method to monitor and record core body temperature during a Whole Body Hyperthermia treatment, compared to an indwelling rectal thermometer.
- Trial name
- NCT02340377
- Testing
- ELITE 3 HQ
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arizona
ADHD
Effects of an Aerobic Exercise Intervention on Core Symptoms, Executive Functioning, and Quality of Life in Children With Attention Deficit Hyperactivity Disorder
Selecting a maternal and child healthcare hospital in Shenzhen City, Guangdong Province, 50 cases of ADHD children as the study subjects, according to the inclusion and exclusion criteria to screen the eligible study subjects…
- Trial name
- NCT06553430
- Testing
- aerobics exercises
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Harbin Medical University
Postpartum Lumbopelvic Pain, Postpartum Pelvic Girdle Pain
Osteopathy in Postpartum Lumbopelvic Pain
Postpartum lumbopelvic pain is a common condition after childbirth and may affect pain levels, physical function, daily activities, and quality of life.
- Conditions
- Postpartum Lumbopelvic Pain, Postpartum Pelvic Girdle Pain, Postpartum Low Back Pain
- Trial name
- NCT07631949
- Testing
- Core Stabilization Exercises, Patient Education, Osteopathic Manipulative Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Halic University
Low Back Pain
Effect of Core Engagement Exercises and Routine Exercise Therapy on Low Back Pain in Middle School Children
Low back pain is defined as the region of pain between the lower ribs and hips. Low back pain with respect to middle school children corresponds to the age where children and adolescents go to school for longer periods of time…
- Trial name
- NCT06182826
- Testing
- Core Stability protocol, Routine exercise therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Systemic Sclerosis
Conception of an ICF Core Set for Systemic Sclerosis
The purpose of this study is to create and validate an ICF core Set for Systemic sclerosis
- Trial name
- SCISCIF (NCT01848418)
- Where
- France
- Volunteers
- 113 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rugby
Core Work and Sports Bandage in Rugby Players
Introduction. Lower limb injuries are characteristic of rugby players. Core exercises aim to improve ankle stability. The ankle bandage in 8 is used in the approach to injuries to provide better stability in the joint.
- Trial name
- NCT03865797
- Testing
- Experimental, Control active
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
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